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1 id, or in cells treated with an inhibitor of lysosomal acid lipase.
2 ined a sequence derived from the propiece of lysosomal acid lipase.
3           The results indicated that 2.5 ppm lysosomal acid lipase, 0.14 ppm liver carboxylesterase,
4    These studies indicate that administrated lysosomal acid lipase affects the atherogenesis by at le
5 evel correlated with increased expression of lysosomal acid lipase, an M2 macrophage marker.
6 not be labeled by commercial probes, such as lysosomal acid lipase and cytosolic phospholipase A2.
7 nriched, as we have previously described, in lysosomal acid lipase and glucocerebrosidase, and locali
8 fic lysosomal signaling mediated by a LIPL-4 lysosomal acid lipase and its lipid chaperone LBP-8 incr
9     This review will focus on the role(s) of lysosomal acid lipase and its use as an enzyme therapy t
10 ction: (a) LDL-CE hydrolysis is catalyzed by lysosomal acid lipase; (b) neither scavenger receptors n
11                                              Lysosomal acid lipase deficiency (LAL-D) is caused by mu
12 n-triggered cell growth and emphysema during lysosomal acid lipase deficiency are partially caused by
13         Fibroblasts from patients with WD (a lysosomal acid lipase deficiency characterized by excess
14 ongation, or desaturation in contrast to the lysosomal acid lipase deficiency found in Wolman disease
15                                              Lysosomal acid lipase deficiency is a rare, autosomal re
16 lacement therapy in children and adults with lysosomal acid lipase deficiency, an underappreciated ca
17  including Fabry's disease, Pompe's disease, lysosomal acid lipase deficiency, and five types of muco
18  of fatty liver, such as HIV, lipodystrophy, lysosomal acid lipase deficiency, familial hypobetalipop
19           Wolman's disease, a severe form of lysosomal acid lipase deficiency, leads to pathologic li
20                                              Lysosomal acid lipase deficiency-which can be diagnosed
21 id abnormalities in children and adults with lysosomal acid lipase deficiency.
22                                By increasing lysosomal acid lipase expression, decreasing metabolic s
23 esteryl ester and triglyceride metabolism in lysosomal acid lipase gene knockout mice (lal-/-) result
24 nsgenic system was used to reintroduce human lysosomal acid lipase (hLAL) expression into LAL gene kn
25 t on protein kinase C-mediated activation of lysosomal acid lipase in Wnt4-deficient bone marrow-deri
26 r the NPC1 or NPC2 protein in NPC disease or lysosomal acid lipase in Wolman disease results in defec
27                                              Lysosomal acid lipase is an essential lipid-metabolizing
28                                              Lysosomal acid lipase (LAL) cleaves cholesteryl esters a
29               The underlying mechanisms that lysosomal acid lipase (LAL) deficiency causes infiltrati
30                                              Lysosomal acid lipase (LAL) deficiency causes systemic e
31                                     Of note, lysosomal acid lipase (LAL) deficiency facilitates melan
32                                              Lysosomal acid lipase (LAL) has been recently identified
33                                              Lysosomal acid lipase (LAL) hydrolyzes cholesteryl ester
34                                              Lysosomal acid lipase (LAL) hydrolyzes cholesteryl ester
35                                              Lysosomal acid lipase (LAL) is a critical lipid hydrolas
36                                              Lysosomal acid lipase (LAL) is a key enzyme that cleaves
37                                              Lysosomal acid lipase (LAL) is essential for the clearan
38                                              Lysosomal acid lipase (LAL) is essential for the hydroly
39                                              Lysosomal acid lipase (LAL) is essential for the hydroly
40                                              Lysosomal acid lipase (LAL) is required for the hydrolys
41                                              Lysosomal acid lipase (LAL) is the critical enzyme for t
42                                              Lysosomal acid lipase (LAL) is the critical enzyme for t
43 eptor CD36 and their subsequent lipolysis by lysosomal acid lipase (LAL) was important for the engage
44                                              Lysosomal acid lipase (LAL), a key enzyme in the metabol
45 cyte fat mobilization, the metabolic role of lysosomal acid lipase (LAL), highly expressed in adipocy
46 e disease (CESD), an inherited deficiency of lysosomal acid lipase (LAL), is an underappreciated caus
47 d a novel downstream transcriptional target, lysosomal acid lipase (LAL).
48  which result from the deficient activity of lysosomal acid lipase (LAL).
49 e studied the effect of lalistat, a specific lysosomal acid lipase (LAL/Lipa) inhibitor on LD degrada
50                                Deficiency of lysosomal acid lipase (LAL; official name Lipa, encoded
51 ion caused by mutations in the gene encoding lysosomal acid lipase (LIPA) that result in reduced or a
52 red for the maintenance of AT; deficiency in lysosomal acid lipase (Lipa), the enzyme required for ly
53  explant culture, establishing dependency on lysosomal acid lipase (LIPA/LAL) and the microphthalmia/
54      In the worm Caenorhabditis elegans, the lysosomal acid lipase LIPL-4 triggered nuclear transloca
55 ulated in mice, genomic clones for the mouse lysosomal acid lipase (mLAL) gene were isolated and char
56  contain 1.5 ppm lipoprotein lipase, 0.1 ppm lysosomal acid lipase, or 0.3 ppm cathepsin D.
57                     RPE-specific knockout of lysosomal acid lipase recapitulates features of AMD.
58 c expression of the lysosomal hydrolase LAL (lysosomal acid lipase) to mobilize FA for FAO and memory
59   Compared with sham-treated mice, the human lysosomal acid lipase-treated mice also have reduced lev
60                      Administration of human lysosomal acid lipase via tail vein into mice with ather
61 essing that involves two lysosomal proteins, lysosomal acid lipase, which hydrolyzes C esters, and NP