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1 m determined using a fusion strategy with T4 lysozyme.
2 RsiV acts as a receptor for lysozyme.
3 ikticus is a typical enzymatic substrate for lysozyme.
4 gg phosphatidylcholine monolayer compared to lysozyme.
5 mune system, such as the cell wall hydrolase lysozyme.
6 ein model systems: barnase, spectrin, and T4 lysozyme.
7 d at a control line comprised of the protein lysozyme.
8 secreting antimicrobial proteins, including lysozyme.
9 gy landscape of the L99A cavity mutant of T4 lysozyme.
10 lfide bonds of intact human insulin (HI) and lysozyme.
11 tants that are resistant to the PG hydrolase lysozyme.
12 nor changes to the native-state stability of lysozyme.
13 g an antimicrobial peptide, B. tabaci c-type lysozyme.
14 he observation of the aggregation process of lysozyme.
15 leading to increased cell susceptibility to lysozyme.
16 th lytic transglycosylases and hen egg white lysozyme.
17 istograms between spin-labels attached to T4 lysozyme.
18 hanced resistance to the antimicrobial agent lysozyme.
19 DTA, sodium ascorbate, hydrogen peroxide and lysozyme.
20 vine serum albumin, human serum albumin, and lysozyme.
21 the wines was not altered by the presence of lysozyme.
22 th more effectively than treatment with free lysozyme.
23 . difficile and the consequent resistance to lysozyme.
24 nism for regulating bacterial sensitivity to lysozyme.
25 eutrophil granule proteins, haptoglobin, and lysozyme.
26 d in MG with a predominance of defensins and lysozymes.
28 aneth cells are the primary source of C-type lysozyme, a beta-1,4-N-acetylmuramoylhydrolase that enzy
29 protects bacteria from the lytic activity of lysozyme, a mammalian innate immune enzyme, and as such
31 e color is formed during the fibrillation of lysozyme, a well-studied protein lacking a prosthetic gr
36 hat SP and SP-XL adsorbents achieved optimum lysozyme adsorption at pH 9 with capacity of ~139.77 and
37 ied out to understand the characteristics of lysozyme adsorption by adsorbents under various conditio
43 first enzyme structure to be determined was lysozyme, also known as the chicken food allergen Gal d
45 exhibited strong binding (Kd </= 2 nm) with lysozyme and abrogated its lytic activity completely, th
47 plete mapping of all four disulfide bonds in lysozyme and all 17 disulfide bonds in human serum album
48 fied the ACE-binding protein in the blood as lysozyme and also a Low Molecular Weight (LMW) ACE effec
49 ilable laboratory diagnostic biomarkers (eg, lysozyme and angiotensin-converting enzyme [ACE]) are la
50 g 6 and 8 glucose moieties were observed for lysozyme and beta-casein, respectively in various heatin
52 l, but these cultures were less resistant to lysozyme and cold treatments than those of the wild-type
54 y, the beta-hairpin region resembles that of lysozyme and contains an aspartate that aligns with lyso
55 investigated in the L99A cavity mutant of T4 lysozyme and derivatives thereof using site-directed spi
56 enerated by tryptic and peptic digestions of lysozyme and insulin, respectively, without prior separa
59 formation of electrostatic complexes between lysozyme and low methoxyl (LM) pectin, mixtures were pre
60 We evaluated constitutive immunity testing lysozyme and natural antibody levels, and blood bacteric
61 ume changes upon unfolding of model proteins lysozyme and ribonuclease A, in solutions containing var
63 isomers located within the binding cleft of lysozyme and those produced from an amyloid-beta segment
64 ere immunohistochemically co-stained for PC (lysozyme) and apoptosis, and PC/crypt and lysozyme inten
66 proteins, BSA, alpha-lactalbumin (alphaLA), lysozyme, and beta-lactoglobulin (betaLG), were studied
67 alt (sodium potassium tartrate), the protein lysozyme, and has been employed for routine crystallogra
69 as accurately mapped to the binding cleft of lysozyme, and in a more complex example, the interaction
70 nocyte-derived macrophages, known to secrete lysozyme, and in the presence of exogenously added lysoz
71 ein-ligand systems (maltose binding protein, lysozyme, and nitrogen regulatory protein) and obtained
73 ss lytic transglycosylases and hen egg white lysozyme, and this differentiating aspartate diminishes
74 hod gives good quantitative results; e.g., a lysozyme-antibody interaction was found to have Kd = 24
77 levels of angiotensin converting enzyme and lysozyme are considered as inflammatory markers for diag
78 ative example shows that amyloid deposits of lysozyme are only the tip of an iceberg hiding a crowd o
80 unoglobulin G, alpha-chymotrypsinogen A, and lysozyme, are shown to generate forces much larger than
81 the performance of this method with hen egg lysozyme as a model system, reproducing its well-known i
85 g/mL and higher), the proteins ubiquitin and lysozyme, as well as the protein domains third IgG-bindi
86 e and contains an aspartate that aligns with lysozyme Asp-52 (a residue critical for catalysis), a co
91 study is the abrogation of lytic activity of lysozyme by a novel glycosylated and surface-localized l
92 on several peptide standards and the protein lysozyme by detecting their thermal decomposition produc
93 enzymes pancreatic ribonuclease (RNASE1) and lysozyme C (LYZ), originally involved in immune defense,
97 M) pectin, mixtures were prepared at a fixed lysozyme concentration (0.714g.L(-1)) by progressive add
99 cific advantage against macrophage-generated lysozyme, conferred by the combination of LprI-HbN durin
100 orption spectroscopy showed modifications in lysozyme conformation during both the aggregation phase
103 strategy developed by pathogens to resist to lysozyme degradation and thus to escape from the host in
105 eric receptors in complex with hen-egg white lysozyme demonstrate how nanomolar affinity binding of a
107 arable concentration gradients, the measured lysozyme diffusion coefficient decreased drastically as
108 At low pH and ionic strength, the measured lysozyme diffusion coefficient increased with the protei
110 sonance (SPR) sensor for the quantitation of lysozyme dimer in monomer-dimer mixtures, reaching a det
111 other methods were used to characterize the lysozyme dimer obtained by cross-linking and confirm the
112 ibrio bacteriovorus, we report a diversified lysozyme, DslA, which acts, unusually, upon (GlcNAc-) de
113 ovine serum albumin, beta-lactoglobulin, and lysozyme, each of which contains multiple internal disul
114 ied proteolytic fragments from ovalbumin and lysozyme, exhibiting varied resistance to pepsinolysis.
115 response to a high-fat diet required TLR9 on lysozyme-expressing cells, and a clinically applicable T
116 l the importance of the beta-sheet region of lysozyme for initiating self-assembly into amyloid fibri
130 TCR-transgenic Th cells specific to hen egg lysozyme (HEL) are adoptively transferred to recipients
131 ells, which express BCRs specific to hen egg lysozyme (HEL) display diminished responsiveness to HEL
133 eic RBCs expressing the HOD antigen (hen egg lysozyme [HEL]-ovalbumin-human transmembrane Duffy(b)) w
134 antigens that are (insulin) or not (hen egg lysozyme; HEL) expressed by ss-cells have proven useful
136 t a dose rate of 40.3 MGy/s on hen egg white lysozyme (HEWL) crystals at RT and cryotemperature, resp
138 -/-) , and Daf1(-/-) B2 cells and in hen egg lysozyme-immunized muMT recipients of MD4 B2 cells on ea
143 d in secondary cell lines in the presence of lysozyme in comparison with isogenic cells expressing th
145 ng of 1,2-azaborines to model cavities in T4 lysozyme in direct comparison to their carbonaceous coun
146 me, and in the presence of exogenously added lysozyme in secondary cell lines where lysozyme levels a
147 e native-state dynamical properties of human lysozyme in the context of its propensity to populate th
148 (CEW) was applied as the crude feedstock of lysozyme in the optimized dynamic membrane chromatograph
151 ginate hydrogel (Si-ALG) and the addition of lysozyme in wines inoculated with encapsulated bacteria
154 nd subsequently applied to chicken egg white lysozyme, in which one biotinylated electrochemistry (EC
155 ncreased, and that the absolute stability of lysozyme increased, whereas the stabilizing effect per m
156 gmatis (8-10-fold) protected its growth from lysozyme inhibition in vitro and enhanced its phagocytos
157 ociated with PTSD in combat veterans: PBMCs' lysozyme inhibition on the lysozyme suppression test, pl
158 ous ACP domains in Dn-ACP with potent C-type lysozyme inhibitor function, and homology of Dn-MIP to o
162 a larger decline in PC/crypt (P = 0.08) and lysozyme intensity (P = 0.08) in W1 in patients who late
169 clohexyl labels were attached to sites on T4 lysozyme introduced by site-directed spin labeling.
170 he leucine-99-to-alanine (L99A) mutant of T4 lysozyme is a model system that has an experimentally we
173 ere we show that during bacterial infection, lysozyme is rerouted via secretory autophagy, an autopha
175 ions of GIT antimicrobials, like cholate and lysozyme, leading us to hypothesize that resistance to i
181 s in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of o
182 ils formed from pathogenic variants of human lysozyme linked with a rare but fatal hereditary systemi
183 ectrostatic interactions in the formation of lysozyme/LM pectin complexes is discussed in relation to
184 d to determine specific conditions of pH and lysozyme/LM pectin ratio for optimal complex aggregation
186 Cox-2 over-expression driven by the chicken lysozyme locus (cLys-Cox-2), which directs integration s
187 eria toxin receptor gene inserted into the P-lysozyme locus, does not affect the maintenance of Lgr5(
188 ith two homologous proteins, namely cationic lysozyme (Lys) and anionic alpha-lactalbumin (aLac), bot
190 s for the release of either Nile Red (NR) or lysozyme (LYS), loaded with gel precursors such as semi-
191 these modified electrodes, a model protein, lysozyme (Lys), was selected as the biological agent to
194 beta-lactoglobulin (betalg) and egg protein lysozyme (Lyso) were developed, using electrostatic inte
195 motrypsin (chy), bovine serum albumin (BSA), lysozyme (lyz) and cytochrome c (cyt c) in singular and
197 iated excision of floxed Ppard driven by the lysozyme M (LysM) promoter (LysM (Cre) :Ppard (fl/fl)).
198 diating NF-kappaB activation, was deleted in lysozyme M (Lysm)-expressing cells, which were found to
199 3 gene in either myeloid cells (by using the lysozyme M [LysM] promotor) or specifically in DCs (by u
200 factor (TNF)-alpha and anti-microbial genes Lysozyme M and SLPI in the colon of Muc4(-/-) mice compa
201 ditional deletion of Stat3 in myeloid cells (lysozyme M Cre mice Stat3(fl/fl) mice), corroborating th
202 Reduced lymphangiogenesis in IL-10(-/-) and lysozyme M Cre Stat3(fl/fl) mice is associated with more
207 re that interacts with the IR via MxiG(C) T4 lysozyme-mediated insertional mutagenesis of MxiK reveal
209 mentation of seed fibrils in the presence of lysozyme monomers at short time scales, followed by the
210 dated using calorimetry data for chicken egg lysozyme, mutated Protein A, three wild-types of haloalk
212 were orally dosed with breastmilk components lysozyme (N-S-LYS) or docosahexaenoic acid (N-S-DHA).
213 nique using different biomolecules including lysozyme, N,N',N"-triacetylchitotriose (TriNAG), aptamer
214 negative co-protein effect with addition of lysozyme, no co-protein effect with soy glycinin or egg
215 percent recovery and purification factor of lysozyme obtained from the chromatography were 93.28% an
216 e that ACC is stabilized by ovalbumin and/or lysozyme or additional vesicle proteins identified in th
217 f protein adsorbed onto these surfaces using lysozyme or fibrinogen as prototype common contaminants.
221 Conversely, daily oral administration of lysozyme prevented expansion of E coli during maternal s
222 cell metaplasia in this region and aberrant lysozyme production are hallmarks of inflammatory bowel
225 romoter and several Fkh-binding sites in the lysozyme promoter, and demonstrated that Fkh-binding sit
227 common scaling of structural fluctuations of lysozyme protein embedded in different environments as t
228 orce microscopy to the assembly of Abeta and lysozyme, protofibrils are observed to bind to the later
233 fication processes in VRE that contribute to lysozyme resistance and enhanced virulence for VRE grown
235 us selection pressure for LD-crosslinking or lysozyme resistance in C. crescentus, the correlation be
236 Among several determinants of cholate and lysozyme resistance in E. faecalis, IreK was the only on
238 However, its impact on N-deacetylation and lysozyme resistance is limited, and its physiological ro
239 n PBP A1, we discovered that GpsB influences lysozyme resistance of L. monocytogenes as mutant strain
240 consistently demonstrated that the increased lysozyme resistance of the DeltagpsB mutant was PgdA-dep
241 uramic acid (MurNAc) residues and conferring lysozyme resistance to modified cell wall peptidoglycans
248 us observation that C. crescentus stalks are lysozyme-resistant, we compared the composition of the p
249 determination in complex with hen egg white lysozyme revealed an extended VH binding interface, with
250 the functional implications include loss of lysozyme secretion, reduced mucociliary clearance and ov
251 We present here the development of a novel lysozyme sensing concept based on the use of Micrococcus
252 production in colonic epithelium suppressed lysozyme-sensitive bacteria and exacerbated colitis.
253 ar patterns and resulted in the expansion of lysozyme-sensitive mucolytic bacteria, including Ruminoc
255 observe the initial stages of aggregation of lysozyme solutions at 60 degrees C and pH 2, through the
260 owed improved survival following exposure to lysozyme, suggesting a possible reason for the selection
262 veterans: PBMCs' lysozyme inhibition on the lysozyme suppression test, plasma cortisol decline on th
263 rescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action by unraveling the kinetic and d
264 pared its interfacial properties to those of lysozyme that is taken as a model globular protein of si
265 e study the thermal denaturation of hydrated lysozyme that occurs when the temperature is increased.
266 t and quantify this PTM in the model protein lysozyme, the biotherapeutic filgrastim, and the Fc part
267 mutations are located in the beta-domain of lysozyme, the region that is predominantly unfolded duri
268 a well-characterized antigen, hen egg white lysozyme, then demonstrate the utility of PMD using infl
269 sensors which are based on the detection of lysozyme through bioaffinity interactions, the bioactivi
270 ed thermal transitions, conjugation to human lysozyme through the retained end-group, and moreover sh
273 e SDBC with a gentle procedure consisting of lysozyme treatment and solubilization with the nonionic
274 ient intermediate species of disease-related lysozyme variants, essentially due to the loss of global
275 resistance to the bacteriolytic activity of lysozyme, virulence, and host innate immune responses.
277 cement observed upon binding of LM pectin to lysozyme was correlated with the formation of intermolec
278 when the rotating speed reached 200 rpm and lysozyme was directly recovered from highly viscous CEW
281 lose matrix the Tm for the doubly labeled T4 lysozyme was long enough to measure an interspin distanc
282 ceptibility to pepsinolysis of ovalbumin and lysozyme was markedly enhanced by heating at 80 degrees
283 tion of apo alpha-lactalbumin (alpha-LA) and lysozyme was measured in the absence and presence of mul
284 roteins bovine insulin and chicken egg white lysozyme was observed at 4 out of 4 and 7 out of 9 of th
285 onnectivity by breaking all peptide bonds in lysozyme, we find that the hysteresis shifts towards the
286 Broadening our scope to cytochrome c and lysozyme, we showed that although compact "native" folds
288 levels of angiotensin converting enzyme and lysozyme were analyzed by enzyme-linked immunosorbent as
293 nal directionality with inhibitor binding to lysozyme, whereas the vibrational energy distribution, a
294 complexes and refolding of betaLG, BSA, and lysozyme, while alphaLA changed to its NIS-bound state i
296 he results showed successful purification of lysozyme with a high recovery yield of 98% and a purific
297 aled by our calculations comparing wild-type lysozyme with a higher catalytic rate double deletion mu
299 , we analyze the folding and unfolding of T4 lysozyme with optical tweezers under a chemo-mechanical
300 ampled diffuse scattering map from triclinic lysozyme with unprecedented accuracy and detail, clearly