ライフサイエンスコーパス: mRNA decay

1 ffective organization strategy for bacterial mRNA decay.

2 sense mutation, indicating nonsense-mediated mRNA decay.

3 in the 3' untranslated region and promoting mRNA decay.

4 r.796c>u were degraded by nonsense-mediated mRNA decay.

5 on, suggesting escape from nonsense-mediated mRNA decay.

6 not support translation but instead promotes mRNA decay.

7 is required for efficient growth and normal mRNA decay.

8 Xrn1, the main 5'-3' exonuclease involved in mRNA decay.

9 poly-(A) tails, the first obligatory step in mRNA decay.

10 enic genes, which triggers nonsense-mediated mRNA decay.

11 e in the cytoplasm and plays a major role in mRNA decay.

12 lational repression in the context of robust mRNA decay.

13 o, how much they contribute to miRNA-induced mRNA decay.

14 d, unexpectedly, enhanced TIS11b activity on mRNA decay.

15 s that recognize a PTC to those that promote mRNA decay.

16 complex, that catalyzes the first step of 5'mRNA decay.

17 initiation and to inhibit nonsense-mediated mRNA decay.

18 attention has been paid to the regulation of mRNA decay.

19 sion of decapping factors, and gene-specific mRNA decay.

20 d innocuous as a result of nonsense-mediated mRNA decay.

21 exon 8 skipping, causing non-sense-mediated mRNA decay.

22 e a required molecule for regulation of SOX2 mRNA decay.

23 hat HIPK2 and HIPK1 restrict CNOT2-dependent mRNA decay.

24 agments may be generated by co-translational mRNA decay.

25 regulation of COX17 demonstrate its role in mRNA decay.

26 d to result in escape from nonsense-mediated mRNA decay.

27 function for ubiquitin in the regulation of mRNA decay.

28 TS1 did not slow the rate of glucose-induced mRNA decay.

29 rotein but was degraded by nonsense-mediated mRNA decay.

30 kinase, an event that is central to trigger mRNA decay.

31 the idea that PA-X induces host shutoff via mRNA decay.

32 ic processing (P) bodies which are sites for mRNA decay.

33 In turn, AGO2-let-7 triggered target mRNA decay.

34 the association of key NMD factors to elicit mRNA decay.

35 n, and termination, ribosome biogenesis, and mRNA decay.

36 SIRT1 and VHL mRNAs, and accelerating target mRNA decay.

37 oligo-U-tail as a molecular mark for global mRNA decay.

38 ptional process that occurs in the cytoplasm-mRNA decay.

39 nd how this binding is transformed to induce mRNA decay.

40 MqsA controls GhoT/GhoS through differential mRNA decay.

41 and MEF2C, independently of Staufen-mediated mRNA decay.

42 nds the DCP2 decapping enzyme and stimulates mRNA decay.

43 ture stop codon affects both translation and mRNA decay.

44 nduced chemokine expression due to increased mRNA decay.

45 th strong contexts promote nonsense-mediated mRNA decay.

46 d in 3'untranslated regions (UTR) to mediate mRNA decay.

47 rmination codon leading to nonsense-mediated mRNA decay.

48 KILLER complex (SKI3), which participates in mRNA decay.

49 on of muscle fibers through targeted, staged mRNA decay.

50 odon which is subjected to nonsense-mediated mRNA decay.

51 e-mRNA splicing, translation repression, and mRNA decay.

52 mechanisms that balance mRNA synthesis with mRNA decay.

53 trolled in their expression by AUF1-targeted mRNA decay.

54 duce host gene expression through widespread mRNA decay.

55 show how it activates multiple steps in late mRNA decay.

56 re phenotypes than alleles displaying mutant mRNA decay.

57 encing multiple steps in AGO2-miRNA-mediated mRNA decay.

58 known for degrading the poly(A) tail during mRNA decay.

59 f translation, which triggers messenger RNA (mRNA) decay.

60 ther slicer-independent mechanisms of target mRNA decay also exist, and, if so, how much they contrib

61 NAs are natural products of RNase E-mediated mRNA decay and associate with major RNA-binding proteins

62 cluding those that led to new insights about mRNA decay and discovery of functional contributions at

63 Erh1-Mmi1 complex (EMC), to promote meiotic mRNA decay and facultative heterochromatin assembly.

64 e role of PARN in miRNA-dependent control of mRNA decay and into the mechanisms behind the regulation

65 lele (C) predicted to cause nonstop-mediated mRNA decay and lower expression of UBASH3A.

66 y recruiting enzymes that function in normal mRNA decay and mRNA degradation is widely thought to occ

67 nding protein Vts1, an important mediator of mRNA decay and mRNA repression whose expression is corre

68 e expression that are supported by regulated mRNA decay and new transcription.

69 ity, as well as gene expression by mediating mRNA decay and protein quality control pathways.

70 tained following silencing of broadly acting mRNA decay and repression factors, and with available CL

71 demonstrate that the regulations of cellular mRNA decay and RNA splicing are compromised by Zika viru

72 the selective influence of RppH on bacterial mRNA decay and show that RppH-dependent degradation has

73 CISH were marked by m(6)A, exhibited slower mRNA decay and showed increased mRNAs and levels of prot

74 f RNA and protein with proposed functions in mRNA decay and storage.

75 We conclude that mRNA decay and surveillance mechanisms collaborate in ac

76 rectly interferes with miR396-mediated AtSVP mRNA decay and synergizes with other effects (e.g. MADS

77 we propose a link between CCR4-NOT-mediated mRNA decay and T cell selection in the thymus.

78 are predicted to result in nonsense-mediated mRNA decay and the absence of WNT1.

79 mRNA turnover keeps a constant ratio between mRNA decay and the dilution of [mRNA] caused by cellular

80 he recent evidence for transcription-coupled mRNA decay and the possible involvement of Snf1, the Sac

81 gous enzymes have important implications for mRNA decay and the regulation of protein biosynthesis in

82 s is further regulated by non-sense-mediated mRNA decay and transcription speed.

83 mRNA decay and translation repression, are independent p

84 avily on RNA-binding proteins that influence mRNA decay and translation.

85 ssociate with decapping factors, and promote mRNA decay and translational repression.

86 sidered the major 3' exonuclease activity in mRNA decay and which is one of four known 3' exonuclease

87 ondensation of Vts1 enhances its function in mRNA decay, and its self-assembly properties are conserv

88 ts precursors, mRNA silencing, regulation of mRNA decay, and regulation of translation.

89 rs of molecular functions like RNA splicing, mRNA decay, and translation control.

90 We find these effects on mRNA decay are sensitive to the number of slow-moving ri

91 nd transcriptome analyses suggested nonsense mRNA decay as a main impact of mutations.

92 process requires factors involved in mutant mRNA decay, as in zebrafish and mouse.

93 An mRNA decay assay demonstrated that disruption of T (porA

94 RNA immunoprecipitation (RIP) and mRNA-decay assays reveal that QKI-7 binds and promotes m

95 iles throughout mRNA lifespan with impact on mRNA decay at short lengths known to sensitize PABP diss

96 rve that BR-body formation promotes complete mRNA decay, avoiding the buildup of toxic endo-cleaved m

97 ly, mRNA 3'-end processing, gene looping and mRNA decay, but they have also been shown to enter the n

98 cells respond to this widespread cytoplasmic mRNA decay by altering RNA Polymerase II (RNAPII) transc

99 regions of select transcripts mediate rapid mRNA decay by recruiting the protein CELF1/CUGBP1.

100 he processes of translational elongation and mRNA decay communicate is unclear.

101 lly colocalizes with DCAP-1, suggesting that mRNA decay components form at least two types of cytopla

102 effects on endonucleolytic nonsense-mediated mRNA decay components, suggesting that de novo CNOT1 var

103 veal the global landscape of cotranslational mRNA decay during Arabidopsis (Arabidopsis thaliana) see

104 sine RNA binding protein 2 (YTHDF2) promotes mRNA decay during cell cycle.

105 t target mRNAs to the cytoplasmic foci where mRNA decay enzymes are active.

106 foci act as mRNA storage depots rather than mRNA decay facilities.

107 function by promoting degradation of the ARE-mRNA decay factor AUF1 by proteasomes.

108 ates these effects by collaborating with the mRNA decay factor KSRP to destabilize the PGC-1alpha mRN

109 most significantly changed and included the mRNA decay factor Tristetraprolin.

110 mRNAs by phosphorylation and inactivation of mRNA decay factor, Tristetraprolin (TTP) in G0.

111 ding surface to successively recruit several mRNA decay factors and show that interaction between tho

112 response to certain stress conditions, many mRNA decay factors are enriched in processing bodies (PB

113 ctivity and impairs the interaction with the mRNA decay factors DCP2, EDC4, and XRN1, but not EDC3, t

114 Suppression of mRNA decay factors leads to the accumulation of oligo-ur

115 mRNA decay factors regulate mRNA turnover by recruiting

116 nslation termination machinery, and multiple mRNA decay factors, but the precise mechanism allowing t

117 Here, we show that C. elegans mRNA decay factors, including the translational represso

118 anslationally repressed mRNAs assembled with mRNA decay factors.

119 dation by recruiting cellular messenger RNA (mRNA) decay factors such as the exosome complex and XRN1

120 mputational model demonstrates that the MazF mRNA-decay feedback loop enables proportional control of

121 thod for estimating the rate of differential mRNA decay from RNA-seq data and model mRNA stability in

122 Cotranslational mRNA decay globally shapes the transcriptome in differen

123 t AUF1 functions in promoting miRNA-mediated mRNA decay globally.

124 readily detectable, and previous studies on mRNA decay have used a handful of highly expressed trans

125 from degradation, uORF translation triggers mRNA decay in a UPF1-dependent manner.

126 sults provide a first step in characterizing mRNA decay in B. burgdorferi and in investigating its ro

127 In this study, we monitored mRNA decay in B. burgdorferi following transcriptional a

128 ng that amlexanox inhibits nonsense-mediated mRNA decay in cells from patients with RDEB that respond

129 tions and structural features reminiscent of mRNA decay in living cells.

130 on with the stim1 3'-UTR and regulated stim1 mRNA decay in opposite directions.

131 ry elements with G-quadruplexes as marks for mRNA decay in P-bodies.

132 emonstrate the prevalence of cotranslational mRNA decay in plant development and its role in translat

133 veal the global landscape of cotranslational mRNA decay in the Arabidopsis thaliana transcriptome.

134 How could mRNA synthesis in the nucleus and mRNA decay in the cytoplasm be mechanistically linked?

135 Patterns of mRNA decay in the wild type were compared with patterns

136 al decreased efficiency of nonsense-mediated mRNA decay in umbilical cord blood, which may reflect sp

137 gnitude of both translational repression and mRNA decay induced by miRNA binding varies greatly betwe

138 Both events reduce the nonsense-mediated mRNA-decay-induced degradation of exon 3*-containing mRN

139 teamine A, an inhibitor of nonsense-mediated mRNA decay, inhibits degradation of aberrant Muc19 trans

140 , Pelechano et al. report that sequencing of mRNA decay intermediates shows surprisingly tight coupli

141 , avoiding the buildup of toxic endo-cleaved mRNA decay intermediates.

142 thway that requires extensive uridylation of mRNA decay intermediates.

143 r of N(6)- methylation, facilitates maternal mRNA decay, introducing an additional facet of control o

144 mRNA decay is an essential and active process that allow

145 licing occurs only exceptionally, and target mRNA decay is induced via AGO-dependent recruitment of d

146 As cotranslational mRNA decay is interconnected with translation, we also a

147 This is surprising, since mRNA decay is known to be a complex process.

148 We demonstrated that cotranslational mRNA decay is regulated by developmental cues.

149 Eukaryotic mRNA decay is tightly modulated by RNA-binding proteins

150 actions between TIS11b and components of the mRNA decay machinery revealed that mimicking phosphoryla

151 ar condensate containing the RNA degradosome mRNA decay machinery, but the biochemical function of su

152 By accelerating global mRNA decay, many viruses impair host protein synthesis,

153 ay of specific transcription termination and mRNA decay mechanisms suggests selection for fine-tuning

154 ng noncoding RNAs, RNA binding proteins, and mRNA decay-mediated control of epidermal stem and progen

155 ll during elongation and trigger pathways of mRNA decay, nascent protein degradation and ribosome rec

156 se with essential roles in nonsense-mediated mRNA decay (NMD) and embryonic development.

157 rotein Y14 is required for nonsense-mediated mRNA decay (NMD) and promotes translation.

158 Exon 5 inclusion triggers nonsense-mediated mRNA decay (NMD) and unproductive translation of Bak1 tr

159 19) report that inhibiting nonsense-mediated mRNA decay (NMD) contributes to the pathogenesis of neur

160 otein synthesis coupled to nonsense-mediated mRNA decay (NMD) controls a switch in Robo3.2 expression

161 Nonsense-mediated mRNA decay (NMD) controls the quality of eukaryotic gene

162 Nonsense-mediated mRNA decay (NMD) degrades EJC-bound mRNA, but the lack o

163 owed that depletion of the nonsense-mediated mRNA decay (NMD) factor SMG7 or UPF1 significantly induc

164 icase that is required for nonsense-mediated mRNA decay (NMD) in eukaryotes, and the predominant view

165 g repression by hnRNPC and nonsense-mediated mRNA decay (NMD) in the quality control and evolution of

166 Nonsense-mediated mRNA decay (NMD) is a cellular quality-control mechanism

167 Nonsense-mediated mRNA decay (NMD) is a cellular surveillance pathway that

168 Nonsense-mediated mRNA decay (NMD) is a conserved translation-coupled qual

169 Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA quality control an

170 Nonsense-mediated mRNA decay (NMD) is a eukaryotic process that targets se

171 Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism

172 Mammalian nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism

173 Nonsense-mediated mRNA decay (NMD) is a quality control mechanism responsi

174 NA regulatory machineries, nonsense-mediated mRNA decay (NMD) is a stress responsive cellular surveil

175 Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that degrades

176 Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recogniz

177 Nonsense-mediated mRNA decay (NMD) is a translation-dependent RNA quality-

178 Nonsense-mediated mRNA decay (NMD) is an essential eukaryotic process regu

179 Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved RNA deca

180 n codon (PTC) mutations by nonsense-mediated mRNA decay (NMD) is an important mechanism of long QT sy

181 Nonsense-mediated mRNA decay (NMD) is the cell's natural surveillance mech

182 Nonsense-mediated mRNA decay (NMD) limits the production of aberrant mRNAs

183 by MoMLV RNase H prevents nonsense-mediated mRNA decay (NMD) of mRNAs.

184 I3K) involved in mediating nonsense-mediated mRNA decay (NMD) of transcripts containing premature sto

185 scripts is mediated by the nonsense-mediated mRNA decay (NMD) pathway and requires a conserved set of

186 We inhibit the nonsense-mediated mRNA decay (NMD) pathway and show that the PTC-containin

187 e evolutionarily conserved nonsense-mediated mRNA decay (NMD) pathway degrades aberrant mRNAs, but al

188 The nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs containing long

189 The nonsense-mediated mRNA decay (NMD) pathway degrades some but not all mRNAs

190 The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnor

191 iple mental illnesses, the nonsense-mediated mRNA decay (NMD) pathway presents an unexplored regulato

192 The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harb

193 The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harb

194 The nonsense-mediated mRNA decay (NMD) pathway selectively eliminates aberrant

195 a predicted target of the nonsense-mediated mRNA decay (NMD) pathway.

196 Nonsense-mediated mRNA decay (NMD) represents a eukaryotic quality control

197 Nonsense-mediated mRNA decay (NMD) represents a highly conserved RNA surve

198 include a class of cryptic nonsense-mediated mRNA decay (NMD) substrates with extended 3'UTRs that ge

199 nd resulting efficiency of nonsense-mediated mRNA decay (NMD) to eliminate potentially toxic proteins

200 he principal regulators of nonsense-mediated mRNA decay (NMD), a cytoplasmic surveillance pathway tha

201 , in some cases triggering nonsense-mediated mRNA decay (NMD), a highly conserved RNA degradation pat

202 ty control pathway, termed nonsense-mediated mRNA decay (NMD), by phosphorylating the NMD factor UPF1

203 plifying this continuum is nonsense-mediated mRNA decay (NMD), the process wherein a premature stop c

204 ontrol mechanisms, such as nonsense-mediated mRNA decay (NMD), which degrades both abnormal as well a

205 Nonsense-mediated mRNA decay (NMD), which degrades transcripts harboring a

206 Here, we review nonsense-mediated mRNA decay (NMD), which is the best-characterized posttr

207 Transcriptomes of nonsense-mediated mRNA decay (NMD)-impaired and heat-stressed plants share

208 nscript for degradation by nonsense-mediated mRNA decay (NMD).

209 the phenomenon is known as nonsense-mediated mRNA decay (NMD).

210 irst degradative event in non-sense-mediated mRNA decay (NMD).

211 to elicit degradation via nonsense-mediated mRNA decay (NMD).

212 with poor translation and nonsense-mediated mRNA decay (NMD).

213 efore potential targets of nonsense-mediated mRNA decay (NMD).

214 unction as a suppressor of nonsense-mediated mRNA decay (NMD).

215 of DNA damage response and nonsense-mediated mRNA decay (NMD).

216 e rapidly degraded through nonsense-mediated mRNA decay (NMD).

217 ression via nonsense-mediated messenger RNA (mRNA) decay (NMD).

218 either the 5' terminus or an internal site, mRNA decay occurs at diverse rates that are transcript s

219 breast tumor cells by selectively enhancing mRNA decay of antiapoptotic gene transcripts, including

220 ated AS event leading to a nonsense-mediated mRNA decay of BARD1.

221 ons to exon 11 resulted in nonsense-mediated mRNA decay of full-length, but not the BRCA1-Delta11q is

222 NA stress response, resulting in accelerated mRNA decay of IkappaBalpha, an inhibitor of proinflammat

223 repression at 5' coding regions with limited mRNA decay or cleavage.

224 r with seed sites in target mRNAs to trigger mRNA decay or inhibit translation.

225 The human nonsense-mediated mRNA decay pathway (NMD) performs quality control and re

226 n, discovery of the 5' to 3' cotranslational mRNA decay pathway demonstrated that both processes are

227 At least one additional mRNA decay pathway is also involved.

228 hat upf3a (a member of the nonsense-mediated mRNA decay pathway) and components of the COMPASS comple

229 s plakoglobin bypassed the nonsense-mediated mRNA decay pathway, resulting in normal levels of the tr

230 two known mediators of the nonsense-mediated mRNA decay pathway.

231 ich functions in the last step of the 3' end mRNA decay pathway.

232 stabilizing it through the nonsense-mediated mRNA decay pathway.

233 licing to surveillance via nonsense-mediated mRNA decay pathway.

234 F1 and UPF3 act in a translation-independent mRNA decay pathway.

235 the importance of translational control and mRNA decay pathways for the successful establishment of

236 A critical step in all 5'-3' mRNA decay pathways is removal of the 5' cap structure,

237 How mRNA decay pathways regulate cellular function in vivo w

238 nthesis and were differentially regulated by mRNA decay pathways, raising the possibility that one di

239 Regulated mRNA decay plays a vital role in determining both the le

240 Eukaryotic 5'-3' mRNA decay plays important roles during development and

241 ity could be linked to mRNA silencing and/or mRNA decay processes.

242 of TIS11b plays a key regulatory role in its mRNA decay-promoting function.

243 reviously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyu

244 h are aggregates whose core constituents are mRNA decay proteins and RNA.

245 her with the stimulation of the sub-steps of mRNA decay provide an effective organization strategy fo

246 thod for unbiased estimation of differential mRNA decay rate from RNA-sequencing data by modeling the

247 BR-bodies stimulate the mRNA decay rate of enriched mRNAs, helping to reshape th

248 Control of messenger RNA (mRNA) decay rate is intimately connected to translation

249 ts demonstrate that heritable differences in mRNA decay rates are widespread and are an important tar

250 mine changes in steady-state mRNA levels and mRNA decay rates following 24-hr exposure to noncytotoxi

251 h significant allele-specific differences in mRNA decay rates have higher levels of polymorphism comp

252 Collectively, these results indicate that mRNA decay rates impact transcription and that gamma-her

253 and measured allele-specific differences in mRNA decay rates in a diploid yeast hybrid created by ma

254 , the contribution of heritable variation in mRNA decay rates to gene expression variation has receiv

255 ta instead arose from 50% increased IL-1beta mRNA decay rates, mediated by Hsp27.

256 31% of genes exhibit allelic differences in mRNA decay rates, of which 350 can be identified at a fa

257 gions contributing to allelic differences in mRNA decay rates.

258 o control output dynamics by altering output mRNA decay rates.

259 profiles revealed that miR396 triggers AtSVP mRNA decay rather than miRNA-mediated cleavage, implying

260 sion through coupling with nonsense-mediated mRNA decay, rather than encode different proteins.

261 a dominant-negative strategy prevented PER1 mRNA decay, reduced tumorigenesis, and increased surviva

262 KA) in the control of TTP family activity in mRNA decay remains largely unknown.

263 How ubiquitin regulates mRNA decay remains unclear.

264 We show that Edc3-mediated RPS28B mRNA decay requires either of two orthologous proteins,

265 iptome analysis in alleles displaying mutant mRNA decay reveals the upregulation of a substantial pro

266 inositol-requiring enzyme 1 (IRE1)-dependent mRNA decay (RIDD), which reduce the load of proteins ent

267 degradation, termed regulated IRE1-dependent mRNA decay (RIDD).

268 as the master regulator of 5'-end-dependent mRNA decay, RppH is important for the ability of pathoge

269 of bound mRNA from the translatable pool to mRNA decay sites, such as processing bodies.

270 Staufen1-mediated mRNA decay (SMD) degrades mRNAs that harbor a Staufen1-b

271 Staufen (STAU)1-mediated mRNA decay (SMD) is a posttranscriptional regulatory mec

272 YHB1 mRNA decay stimulation by Puf proteins is also responsiv

273 derived platelet-like particles to show that mRNA decay strongly shapes the nascent platelet transcri

274 Data from mRNA decay studies and quantitative primer extension ass

275 A helicase associated with nonsense-mediated mRNA decay, suggesting that amlexanox inhibits nonsense-

276 LIN41 triggers repression of translation or mRNA decay, suggesting that one factor may use two indep

277 at synaptic activity simultaneously triggers mRNA decay that eliminates Arc mRNA from inactive dendri

278 t1 protein is a central player of eukaryotic mRNA decay that has also been implicated in translationa

279 NA decapping is a central step in eukaryotic mRNA decay that simultaneously shuts down translation in

280 ion programs by modulating transcription and mRNA decay.The regulation of overall mRNA turnover keeps

281 ome biogenesis and translation by modulating mRNA decay through a balance of PKA and Hog1 signalling.

282 The Ccr4-Not complex initiates mRNA decay through deadenylation and activation of decap

283 MCPIP1 promotes Gata3 mRNA decay through the RNase domain.

284 Deadenylases promote miRNA-induced mRNA decay through their interaction with miRNA-induced

285 ed phagocytosis by lung macrophages, linking mRNA decay to adaptation and immune evasion.

286 ite, is sufficient to confer glucose-induced mRNA decay upon heterologous transcripts.

287 ow that miR396 triggers AtSVP messenger RNA (mRNA) decay using genetic approaches, a reporter assay,

288 tical step in mRNA turnover, linking MPK4 to mRNA decay via PAT1 provides another mechanism by which

289 ACOT7 mRNA decay was triggered by the microRNA miR-9 in a WIG1

290 proaches to measure exogenous and endogenous mRNA decay, we define which codons are associated with s

291 MicroRNAs able to induce hOCT1 mRNA decay were analyzed in paired samples of TCGA-CHOL

292 nation codon that triggers nonsense-mediated mRNA decay when included in the transcript.

293 ediated repression of protein expression and mRNA decay, whereas depletion of other CNOT components h

294 R sensor IRE1alpha transiently catalyzed DR5 mRNA decay, which allowed time for adaptation.

295 SF2 Pro95 hot spot mutations elicit enhanced mRNA decay, which is dependent on sequence-specific RNA

296 to suppress host protein synthesis via host mRNA decay, which is mediated by endonuclease activity i

297 lization of EGFR transcripts as PLD2 delayed mRNA decay, which prolonged their half-lives.

298 -466i functioned to mediate GM-CSF and IL-17 mRNA decay, which was confirmed by in vitro luciferase a

299 ing demonstrated that Msi2 promotes targeted mRNA decay without affecting translation efficiency.

300 the ADH2 promoter prevented glucose-induced mRNA decay without altering the start site of transcript