1 n about the processes that control levels of
mTOR protein.
2 different levels of total and phosphorylated
mTOR protein.
3 vation of the mammalian target of rapamycin (
mTOR) protein,
a serine/threonine protein kinase that re
4 phorylation of retinoblastoma, Skp2, and Akt-
mTOR proteins,
accumulation of p27(Kip1), and induction
5 p53 activity, altered translation of AKT and
mTOR proteins,
and the stress response of the endoplasmi
6 The raptor-
mTOR protein complex is a key component of a nutrient-se
7 hibitors of mTOR, only partially inhibit one
mTOR protein complex.
8 modifies GbetaL, influences the assembly of
mTOR protein complexes, and regulates mTOR activity.
9 We found a reduction in AKT and
mTOR protein expression and/or phosphorylation state in
10 Deletion of IR elevated FoxO and decreased
mTOR protein expression, which further decreased the exp
11 effector S6K1, maintenance of cell size, and
mTOR protein expression.
12 was associated with upregulation of RyR2 and
mTOR protein expression.
13 and protein levels and the shuttling of the
mTOR protein from its normal, predominantly mitochondria
14 Conversely, loss of
mTOR protein induced apoptosis due to up-regulation of c
15 The
mTOR protein is a master regulator of cell growth and pr
16 Targeting the mammalian target of rapamycin (
mTOR) protein is a promising strategy for cancer therapy
17 The mammalian Target of Rapamycin (
mTOR) protein is a serine-threonine kinase that regulate
18 For example, PKA (protein kinase A) and AKT/
mTOR (protein kinase B/mammalian target of rapamycin) pa
19 The effects of insulin on increasing
mTOR protein kinase activity and on decreasing mTAb1 rea
20 mTOR protein kinase activity was measured in immune comp
21 The
mTOR protein kinase forms two multiprotein complexes, mT
22 The
mTOR protein kinase has emerged as a critical growth-con
23 The
mTOR protein kinase is the target of the immunosuppressi
24 gs indicate that Pro is a determinant of the
mTOR protein kinase specificity and that mTOR contribute
25 R with mTAb1, an antibody that activates the
mTOR protein kinase.
26 ralfold, indicating that mTAb1 activates the
mTOR protein kinase.
27 imately 25 y ago led to the discovery of the
mTOR protein kinase.
28 ar to that of mammalian target of rapamycin (
mTOR) protein kinase deletion or mTOR inhibition.
29 The mammalian target of rapamycin (
mTOR) protein kinase is a master growth promoter that nu
30 The mammalian target of rapamycin (
mTOR) protein kinase responds to diverse environmental c
31 Even though
mTOR/protein kinase B signaling is important for adipoge
32 responses 1 (REDD1), a negative regulator of
mTOR/protein kinase B, is poorly understood.
33 In accordance with this, reduction in the
mTOR protein level by small interfering RNA resulted in
34 The
mTOR protein level increases 10-fold during differentiat
35 ived from these mice show a 50% reduction in
mTOR protein levels and phosphorylation of S6 kinase 1 T
36 Together, miR-100 and miR-101 reduced
mTOR protein levels.
37 growth, the mechanistic target of rapamycin (
mTOR) protein operates as part of two molecularly and fu
38 F-kappaB, ERK, IL-1beta and enhanced Akt and
mTOR proteins phosphorylation.
39 OR ASO resulted in a significant decrease in
mTOR protein,
pS6 and pAktSer(473).
40 levels of the S100B calcium-binding protein,
mTOR proteins RAPTOR and P70S6, the AMP-kinase catalytic
41 We discover unique expansions in
mTOR protein sequence among urodele amphibians.
42 nd that both endogenous and recombinant FRAP/
mTOR proteins show localization predominantly in the end
43 Increased phospho-
mTOR protein was detected in irradiated human umbilical
44 Unexpectedly,
mTOR proteins with those conserved leucines mutated to a