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1 11-member cyclic peptide, whereas FK506 is a macrolide antibiotic.
2 rophylactic treatment with clarithromycin, a macrolide antibiotic.
3 translocation pathways for a bile acid and a macrolide antibiotic.
4                  Tylosin is a broad-spectrum macrolide antibiotic.
5 e novel form of proarrhythmia seen with this macrolide antibiotic.
6 to the first total synthesis of this complex macrolide antibiotic.
7 s such as cyclosporin, statins, taxanes, and macrolide antibiotics.
8 hylamino)-3,4,6-trideoxyhexose found in some macrolide antibiotics.
9 ents with acute coronary syndrome when given macrolide antibiotics.
10 duct ions of explosives, acylcarnitines, and macrolide antibiotics.
11 ed activity of the broader spectrum group of macrolide antibiotics.
12 ng antibiotic resistance against a number of macrolide antibiotics.
13      Ketolides represent a new generation of macrolide antibiotics.
14  contributes to its ability to generate four macrolide antibiotics.
15 odular PKSs, which catalyze the synthesis of macrolide antibiotics.
16 ts ability to produce two distinct groups of macrolide antibiotics.
17  insights for future development of improved macrolide antibiotics.
18 ally involved in the biosynthesis of diverse macrolide antibiotics.
19 hat it would overlap with the ribosome-bound macrolide antibiotics.
20 hrough genetic analysis to be susceptible to macrolide antibiotics.
21 nthesis may modulate site-specific action of macrolide antibiotics.
22 al cells treated with high concentrations of macrolide antibiotics.
23 tunnel is the target of clinically important macrolide antibiotics.
24 tcomes in a mouse model with beta-lactam and macrolide antibiotics.
25 increasingly resistant to currently marketed macrolide antibiotics.
26 clav, clindamycin, and fluoroquinolones) and macrolide antibiotics; a hand hygiene campaign; hospital
27 tion of 8-deoxyamphotericin B to the polyene macrolide antibiotic, amphotericin B.
28                  Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves
29 trE efflux pump system confers resistance to macrolide antibiotics and antimicrobial substances of th
30 iation pathways of a variety of ions such as macrolide antibiotics and hydrogen-bonded complexes.
31 rrent use of terfenadine and contraindicated macrolide antibiotics and imidazole antifungals continue
32 provides a platform for the discovery of new macrolide antibiotics and may also serve as the basis fo
33 atal cases were less likely to have received macrolide antibiotics and more likely to have received s
34 transporter has been implicated in efflux of macrolide antibiotics and secretion of enterotoxin STII.
35 one-year study on the occurrence and fate of macrolide antibiotics and their metabolites, synthesis b
36 S) genes: derivatives of medically important macrolide antibiotics and unusual polycyclic aromatic co
37 ition of carbamazepine metabolism by certain macrolide antibiotics, antifungals, verapamil, diltiazem
38                         Prior treatment with macrolide antibiotics appeared to be protective against
39                              Beta-lactam and macrolide antibiotics are considered safe in pregnancy a
40                      The efficacies of these macrolide antibiotics are markedly reduced in the absenc
41                                      Polyene macrolide antibiotics are naturally occurring antifungal
42                             Although several macrolide antibiotics are proarrhythmic and associated w
43 natives to erythromycin, including the newer macrolide antibiotics, are now part of the recommendatio
44 6-trideoxyhexose found, for example, in such macrolide antibiotics as erthyromycin, azithromycin, and
45 hromboembolism (VTE), using roxithromycin, a macrolide antibiotic, as comparator.
46                                          The macrolide antibiotic azithromycin has anti-inflammatory
47 udy was to assess whether treatment with the macrolide antibiotic azithromycin improves endothelial f
48                              The widely used macrolide antibiotic azithromycin increases risk of card
49                             We show that the macrolide antibiotic azithromycin reduced viral prolifer
50                               Rationale: The macrolide antibiotic azithromycin reduces exacerbations
51 assess whether short-term treatment with the macrolide antibiotic azithromycin reduces recurrent isch
52           Here we tested the capacity of the macrolide antibiotic azithromycin to neutralize the dele
53                                          The macrolide antibiotic bafilomycin A1 inhibited CS-induced
54                  Treatment of cells with the macrolide antibiotic bafilomycin A1, an inhibitor of vac
55                                              Macrolide antibiotics benefit patients with a variety of
56                                              Macrolide antibiotics bind in the nascent peptide exit t
57 giogenesis stimulation can be blocked by the macrolide antibiotic borrelidin (BN), which exhibits a b
58  Moreover, high-resolution structures of two macrolide antibiotics bound to the unmodified ribosome r
59 resent a practical, fully synthetic route to macrolide antibiotics by the convergent assembly of simp
60 nt data challenged this view by showing that macrolide antibiotics can differentially affect synthesi
61                            More than 300 new macrolide antibiotic candidates, as well as the clinical
62  an opportunity to potentially repurpose the macrolide antibiotic clarithromycin to treat tuberculosi
63 ing reports regarding the association of the macrolide antibiotic clarithromycin with cardiovascular
64 he potential anti-inflammatory activity of 3 macrolide antibiotics, clarithromycin, roxithromycin, an
65                                          The macrolide antibiotic concanamycin is a potent and specif
66  patient group with common coprescription of macrolide antibiotics.Conclusions: This pilot study supp
67                             Glycosylation of macrolide antibiotics confers host cell immunity from en
68 somes, (ii) inhibition of CD4 degradation by macrolide antibiotics does not restore surface expressio
69 pite only 3.7% of children having received a macrolide antibiotic during the hospitalisation.
70  an antifungal drug of the family of polyene macrolide antibiotics, elevated YFP expression by the re
71                                          The macrolide antibiotic erythromycin A and its semisyntheti
72                                          The macrolide antibiotic erythromycin also interacted with t
73  megalomicea and differs from the well-known macrolide antibiotic erythromycin by the addition of a u
74 oxyglucose, is an unusual sugar found on the macrolide antibiotic erythromycin, and it has been shown
75 ), the parent aglycone of the broad spectrum macrolide antibiotic erythromycin.
76               Further, our structures of the macrolide antibiotics erythromycin and azithromycin in c
77  these proteins can confer resistance to the macrolide antibiotic, erythromycin.
78  intriguing class of mutants is resistant to macrolide antibiotics even though these drugs still bind
79                                              Macrolide antibiotics, exemplified by erythromycin, bind
80                            This new class of macrolide antibiotics exhibited potent activity against
81 During antibiotic stewardship, use of 4C and macrolide antibiotics fell by 47% (mean decrease 224 def
82  as many commonly used drug classes, such as macrolide antibiotics, fluoroquinolone antibiotics, anti
83                                              Macrolide antibiotic for 3 months was associated with im
84 ation and disease progression, we tested two macrolide antibiotics for their ability to inhibit Nef f
85 ermination of azithromycin, a broad-spectrum macrolide antibiotic, from various biological samples (u
86 Growing resistance toward ribosome-targeting macrolide antibiotics has limited their clinical utility
87                                              Macrolide antibiotics have been shown beneficial in cyst
88 reviously to be involved in interaction with macrolide antibiotics, have been modeled in the crystall
89                     The cladinose-containing macrolide antibiotic in the tunnel positions the nascent
90  confer resistance to erythromycin and other macrolide antibiotics in a variety of bacteria.
91 nd, randomised, placebo-controlled trials of macrolide antibiotics in adult patients with bronchiecta
92 site-specific oxidation of the precursors to macrolide antibiotics in the genus Streptomyces introduc
93 cts, and TPs for the overall mass balance of macrolide antibiotics in urban wastewater systems.
94 o)-3,4,6-trideoxyhexose found in a number of macrolide antibiotics including methymycin (2), neomethy
95                                              Macrolide antibiotics, including azithromycin, can reduc
96                                              Macrolide antibiotics, including azithromycin, have been
97                                              Macrolide antibiotics, including erythromycin, clarithro
98 induced lethality and identified a series of macrolide antibiotics, including roxithromycin, that pot
99 ion leading to the production of a series of macrolide antibiotics, including the natural ketolides n
100 ptide sequence and the chemical structure of macrolide antibiotic, indicating possible interaction be
101                     Rapamycin, a lipophilic, macrolide antibiotic, induces autophagy by inactivating
102 ing "plug-in-the-bottle" model suggests that macrolide antibiotics inhibit translation by binding ins
103                Ceftriaxone with or without a macrolide antibiotic is a recommended treatment for pati
104                                Resistance to macrolide antibiotics is a global concern in the treatme
105                                Resistance to macrolide antibiotics is conferred by mutation of A2058
106 resistance of group A Streptococcus (GAS) to macrolide antibiotics is now a worldwide problem.
107   A key mechanism of bacterial resistance to macrolide antibiotics is the dimethylation of a nucleoti
108                               A new class of macrolide antibiotics, known as ketolides, show improved
109                                              Macrolide antibiotics, like erythromycin, clarithromycin
110                                              Macrolide antibiotics, long recognized for antibacterial
111             A prolonged course (3 months) of macrolide antibiotic may be considered for patients with
112                   Previous studies show that macrolide antibiotics may be efficacious in the treatmen
113 - and 14-membered aglycone precursors of the macrolide antibiotics methymycin and picromycin, respect
114 nsferase involved in the biosynthesis of the macrolide antibiotics methymycin, neomethymycin, narbomy
115            Increasing evidence suggests that macrolide antibiotics might be beneficial in patients wi
116                     Rapamycin, an antifungal macrolide antibiotic, mimics starvation conditions in Sa
117  oxidative tailoring of the 16-membered ring macrolide antibiotic mycinamicin II in the actinomycete
118 or the production of hybrid glycopeptide and macrolide antibiotics, novel anthelminthic agents and no
119                                These include macrolide antibiotics, omalizumab, tumor necrosis factor
120 lipidemic medications (OR = 0.39, P = .004), macrolide antibiotics (OR = 0.40, P = .03), and calcium
121 ed by prescription fills for a penicillin or macrolide antibiotic, or for trimethoprim-sulfamethoxazo
122 ycin was associated with previous use of any macrolide antibiotic (P < 0.001), and resistance to metr
123         Emergence of bacterial resistance to macrolide antibiotics, particularly in Gram-positive bac
124                                              Macrolide antibiotics penetrate cells, but the mechanism
125 MtrE multidrug-resistance efflux pump expels macrolide antibiotics, penicillin, and antimicrobial eff
126    The total synthesis of the potent polyene macrolide antibiotic pentamycin was accomplished by an e
127  epoxidation of 4,5-desepoxypimaricin to the macrolide antibiotic, pimaricin, reveals key catalytic s
128      Telithromycin (2) is a third-generation macrolide antibiotic prepared from erythromycin (1) and
129                            The proportion of macrolide antibiotics prescribed increased from 36.8% to
130                         Associations between macrolide antibiotics prescribing during pregnancy and a
131            However, long-term treatment with macrolide antibiotics presents a considerable risk for p
132 ch as the prostanoids, indole alkaloids, and macrolide antibiotics, provide ample evidence for the en
133                                          The macrolide antibiotic rapamycin effectively blocks oncoge
134                                          The macrolide antibiotic rapamycin inhibits the mammalian ta
135 The potent antiproliferative activity of the macrolide antibiotic rapamycin is known to involve bindi
136 t has been suggested that the ability of the macrolide antibiotic rapamycin to inhibit 4BP-1 phosphor
137             Previously, we reported that the macrolide antibiotic rapamycin, but not the related comp
138                                              Macrolide antibiotic rapamycin, in complex with a cytoso
139                                              Macrolide antibiotics reduced the frequency of exacerbat
140  have demonstrated that chronic therapy with macrolide antibiotics reduces the morbidity of patients
141 erties of the ribosomal exit tunnel and that macrolide antibiotics reshape the cellular proteome rath
142 onas vaginalis Sequencing was used to assess macrolide antibiotic resistance among M. genitalium-posi
143 lly transmitted organisms, and high rates of macrolide antibiotic resistance in a diverse sample of s
144 transmitted organisms and the frequency of a macrolide antibiotic resistance phenotype were determine
145 ositions has previously been associated with macrolide antibiotic resistance.
146        The total synthesis of the antifungal macrolide antibiotic roxaticin has been accomplished.
147              The asymmetric synthesis of the macrolide antibiotics (+)-rutamycin B (1) and (+)-oligom
148  new class of macrocyclic HDACi based on the macrolide antibiotics skeletons.
149 reactionary sites which are complementary to macrolide antibiotic spiramycin (SPI) were synthetized b
150                                              Macrolide antibiotics such as erythromycin may improve c
151 r aromatic compounds such as mithramycin and macrolide antibiotics such as erythromycin.
152              The antibacterial properties of macrolide antibiotics (such as erythromycin, tylosin, an
153                                              Macrolide antibiotics, such as erythromycin and josamyci
154 ling in the presence of clinically important macrolide antibiotics, such as erythromycin, leading to
155 desosamine are aminohexoses found in several macrolide antibiotics, such as tylosin and methymycin, r
156 of which were predicted to be susceptible to macrolide antibiotics, suggesting that different strains
157                          Management includes macrolide antibiotics, supplemental oxygen, modest hydra
158                               Rapamycin is a macrolide antibiotic that inhibits vascular smooth muscl
159                            Azithromycin is a macrolide antibiotic that is active against several peri
160                      Rapamycin, a lipophilic macrolide antibiotic that regulates mitochondrial transm
161 lav, and third-generation cephalosporins, or macrolide antibiotics that exceeded hospital-specific th
162  means to control the biological activity of macrolide antibiotics, the availability of macrolide gly
163 rate specificity of oxidative enzymes toward macrolide antibiotics, the x-ray structure of CYP154C1 f
164                         Treatment depends on macrolide antibiotic therapy and intubation, with assist
165     Here we demonstrate that a single pulsed macrolide antibiotic treatment (PAT) course early in lif
166 ne (1), the parent aglycone precursor of the macrolide antibiotic tylosin.
167                                          The macrolide antibiotic, tylosin (Ty), is produced by Strep
168 proved latrine (0.89; 0.82-0.97), and recent macrolide antibiotic use (0.68; 0.63-0.74).
169                       BOTTOM LINE Continuous macrolide antibiotic use for prophylaxis was associated
170 not, which makes comparisons between these 2 macrolide antibiotics useful in assessing clinically imp
171 ide synthase (PKS) biosynthetic tailoring of macrolide antibiotics usually involves one or more oxida
172 uvenimicin, M-4365, and rosamicin classes of macrolide antibiotics via late-stage diversification.
173  and actively extrudes substrates, including macrolide antibiotics, virulence factors, peptides and c
174   The completion of the synthesis of the two macrolide antibiotics was accomplished by the union of t
175                                              Macrolide antibiotics were discovered over 50 years ago
176 xposure has ceased.High or multiple doses of macrolide antibiotics, when given early in life, can per
177                                              Macrolide antibiotics, which have anti-inflammatory and
178 e observed after exposure to clindamycin and macrolide antibiotics, which have been proposed to targe
179 ion experiment over 25 days except for three macrolide antibiotics, which reached saturation at 300 n
180                          Clarithromycin is a macrolide antibiotic widely used for eradication of Heli
181                       Solithromycin, a novel macrolide antibiotic with both intravenous and oral form
182                              Azithromycin, a macrolide antibiotic with immunomodulatory effects, is u
183 , led to the discovery of gladiolin, a novel macrolide antibiotic with potent activity against Mycoba
184                              Interactions of macrolide antibiotics with biological membranes contribu
185 ally contribute to a new generation of novel macrolide antibiotics with enhanced antifungal and/or an
186 the interaction strength and localization of macrolide antibiotics with membrane-mimetics.
187 and potency by bafilomycin and concanamycin, macrolide antibiotics with similar structures.
188  our knowledge of the mode of interaction of macrolide antibiotics with their ribosomal target and of
189 eceptor (e.g., some anticancer compounds and macrolide antibiotics), with subsequent effects on trans
190 olactones and fluorinated derivatives of the macrolide antibiotics YC-17 and methymycin.
191                                              Macrolide antibiotics yield high concentrations in infla

 
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