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1 pole of endomesodermal precursors (2M and 3E macromeres).
2 st quartet micromeres specify the D quadrant macromere.
3 interaction between the micromeres and the D macromere.
4 development because it is too far from the D macromere.
5 MAPK and biasing the specification of the 3D macromere.
6 ve glands, which arise from the fourth order macromeres.
7  parenchyma, is generated by both third duet macromeres.
8  derived from the two diagonally opposed 2M/ macromeres.
9 4d) and some of its derivatives and selected macromeres.
10 cation of 3D among four initially equivalent macromeres.
11 der cell, empowering its great-granddaughter macromere 3D to act as a single-celled organizer that in
12 th quartet micromeres as well as the vegetal macromeres (4A, 4B, 4C, 4D).
13 c Ilyanassa obsoleta demonstrate that the 3D macromere acts as an embryonic organizer, by signaling t
14          As Notch is maternally expressed in macromeres, additional components must be downstream of
15 ends on autonomous beta-catenin signaling in macromeres and does not require micromere or veg2-induct
16 ular, at the eight-cell stage there are four macromeres and four micromeres, and each of these cells
17 g in an embryo comprised of eight cells-four macromeres and four micromeres.
18 n, while high levels persist in their sister macromeres and in the mesomeres.
19 ge, which results in two large vegetal pole 'macromeres' and numerous small animal pole 'micromeres'.
20 yo are larger than the corresponding vegetal macromeres, and generate most of the larval ectoderm.
21 the progeny of animal micromeres and vegetal macromeres are established during the interval between t
22 either the E or the M lineages (the 3E or 2M macromeres) are also required.
23 shape changes involving protrusion of the 3D macromere at the 24-cell suggest that the D quadrant is
24 cell interactions between the micromeres and macromeres at the 24- to 36-cell stage.
25                                        These macromeres become internalized as micromere progeny prol
26 res and the vegetal macromeres specify which macromere becomes the 3D cell during the interval betwee
27 , MAPK activation was not detected in the 3D macromere but was observed in one of its daughter cells,
28 ot influenced by its close position to the D macromere, but is restricted by its polar lobe lineage.
29 xpressed maternally and in all micromere and macromere cells throughout cleavage.
30 cell quadrant on the opposite side, with its macromere centered under the greatest number of the rema
31 en the sister cells DNOPQ and DM, progeny of macromere D' at fourth cleavage: DNOPQ is the segmental
32 cific mechanisms operate, as turnover in the macromeres depends on entry of SoxB1 into nuclei, and on
33 so suppresses accumulation of its message in macromere-derived blastomeres.
34                                              Macromere-derived LvDelta is necessary for blastocoelar
35  which initiates expression in micromere and macromere descendant cells early in cleavage, Tcf1 sites
36 lso demonstrate that LvDelta is expressed by macromere descendants during mesenchyme blastula and ear
37  is required for the specification of the 3D macromere, during the late 16-cell through early 24-cell
38 -competent micromeres fail to induce SMCs if macromeres express dominant-negative Notch.
39 eptive to the micromere inductive signal the macromeres first must transport beta-catenin to their nu
40 ust be downstream of nuclear beta-catenin in macromeres for these cells to receive and transduce the
41                         The two opposing 2M/ macromeres generated a unique set of circumpharyngeal mu
42 three of the macromeres, while the remaining macromere generates the visceral mesoderm.
43 eatments to the LAL to consume unpolymerized macromeres in the LAL.
44 quartet micromere relative to the inducing D macromere is important for determining whether or not it
45 larvae if the prospective D blastomere or 3D macromere is removed.
46  MAPK activation, as does ablation of the 3D macromere itself.
47 meres at the vegetal pole separate from four macromeres just above them in an unequal cleavage.
48 specify 3D potential, but rather makes the D macromere lineage responsive to some intercellular signa
49 beled micromere is placed ectopically at the macromere/mesomere boundary, the PMC progeny ingress ect
50 re induction signal, beta-catenin must enter macromere nuclei.
51  schedule of 3D (relative to the third-order macromeres of the A, B and C quadrants).
52                      Hro-hes is expressed in macromeres, pro-teloblasts, teloblasts and primary blast
53 tion signal is passed from the micromeres to macromere progeny between the eighth and tenth cleavage.
54                                          The macromere progeny receive the micromere induction signal
55                                          For macromere progeny to be competent to receive the microme
56 t the vegetal pole results in the failure of macromere progeny to specify secondary mesenchyme cells
57 tage blastomeres further subdivides fates of macromere progeny to yield major embryonic tissues.
58 condary mesoderm cell (SMC) specification in macromere progeny, and expression of the early endomesod
59 MCs, most likely through direct contact with macromere progeny, or at most a cell diameter away.
60 on of SoxB1, first in micromeres and then in macromere progeny.
61 xpression of an activated Notch construct in macromeres rescues SMC specification in the absence of i
62                                       The 3D macromere serves as a dorsal organizer and gives rise to
63 the first quartet micromeres and the vegetal macromeres specify which macromere becomes the 3D cell d
64    Significantly, misexpression of Lvalx1 in macromeres (the progenitors of NSM cells) is sufficient
65 ctivities and their region of overlap in the macromeres, which specifies these cells as early mesendo
66    The ectoderm originates from three of the macromeres, while the remaining macromere generates the