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1 pronounced uniaxial anisotropy field in each magnetosome.
2 of new magnetosomes in between pre-existing magnetosomes.
3 inner cell membrane, while McaB localizes to magnetosomes.
4 nctioned as a navigation aid, akin to modern magnetosomes.
5 ic filamentous fossil to construct synthetic magnetosomes.
6 assemblies of magnetic nanoparticles called magnetosomes.
7 their surrounding membranes are referred to magnetosomes.
8 to the intrinsic magnetic properties of the magnetosomes.
9 domain crystals which are incorporated into magnetosomes.
10 magnetic iron-rich mineral particles called magnetosomes.
11 ganization of subcellular organelles, termed magnetosomes.
12 s build-up of cytoskeletal filaments between magnetosomes.
13 nant formation of shorter, doubled chains of magnetosomes.
14 bacteria, to combine their magnetic moments, magnetosomes align along filaments formed by a bacterial
17 The crystalline habit and composition of all magnetosomes analyzed with high-resolution transmission
19 new insight into the biogenesis of bacterial magnetosomes, and links these organelles to a newly reco
20 opment of bioprocesses for the production of magnetosomes, and will increase understanding of this fa
21 ting in magnetosome formation and shows that magnetosomes are assembled in a step-wise manner in whic
25 Using electron cryotomography, we found that magnetosomes are invaginations of the cell membrane flan
27 magnetic minerals identified in prokaryotic magnetosomes are magnetite (Fe(3) O(4) ) and greigite (F
30 spectroscopy studies reveal that full-sized magnetosomes are seen 15 min after formation is initiate
33 this way, we quantitatively characterize the magnetosome arrangement in both wild-type cells and Delt
37 ach to find that MamE, and another predicted magnetosome-associated protease, MamO, likely function a
39 of its conserved core are not essential for magnetosome biogenesis and that nonconserved genes are i
40 en to the host cell, the benefit provided by magnetosome biomineralization beyond magnetotaxis can be
44 h a dramatic increase in cell curvature, and magnetosome chain mislocalization or complete chain disr
46 keleton, the "magnetoskeleton." However, how magnetosome chain organization and resulting magnetotaxi
47 alization originates from a common ancestor, magnetosome chain organization has distinct evolutionari
49 LimJ leads to static filaments, a disrupted magnetosome chain, and an anomalous build-up of cytoskel
50 Here, we show that the fragmented nature of magnetosome chains in Magnetospirillum magneticum AMB-1
51 as well as nano-sized magnetotactic bacteria magnetosome chains, have been reported in clay-rich sedi
56 reason for the persistency of bullet-shaped magnetosomes during the evolutionary development of magn
58 me island (MAI) is known to be essential for magnetosome formation and contains most of the genes pre
59 in understanding the molecular mechanisms of magnetosome formation and magnetite biomineralization.
60 f more than a dozen factors participating in magnetosome formation and shows that magnetosomes are as
63 everal phyla and exhibit diverse phenotypes, magnetosome formation has been mechanistically studied i
66 ed mutants with defects at various stages of magnetosome formation to identify factors involved in co
69 umerous genetic and proteomic studies of the magnetosome-formation process, there have been only limi
70 atrix in which iron accumulates close to the magnetosome forming a continuous layer visually appearin
71 magnetotactic behaviour and characterize the magnetosomes from a flagellated protist using culture-in
72 illum magneticum sp. AMB-1, and other MTB, a magnetosome gene island (MAI) is essential for every ste
74 (MTB), the magnetic properties of magnetite magnetosomes have been extensively studied using widely
76 Here we evaluated the thermal stability of magnetosomes in a temperature range between 150 and 500
80 provides some insight into the stability of magnetosomes in specific environments over geological pe
81 ryotic cytoskeletal filament which organizes magnetosomes into a sensory structure capable of alignin
85 mes of the Magnetospirillum magneticum AMB-1 magnetosome island, MamP and MamT, are essential to thei
88 a diverse group of bacteria that synthesise magnetosomes, magnetic membrane-bound nanoparticles that
89 ain environments after cell death and lysis, magnetosome magnetite crystals contribute to the magneti
94 ne cluster encodes for factors important for magnetosome membrane biogenesis, for targeting of protei
95 leavage of MamD by MamE protease is blocked, magnetosome membrane growth and biomineralization are se
96 the protease activity of MamE is disrupted, magnetosome membrane growth is restricted, which, in tur
101 contrast, MmsF, a previously uncharacterized magnetosome membrane protein encoded within the same reg
102 regulator protein of nanoparticle formation, magnetosome membrane specific F (MmsF), was recently dis
105 required for the subcellular organization of magnetosomes, membrane-bound organelles that aid in navi
107 irillum magneticum str AMB-1 is able to form magnetosome membranes but not magnetite crystals, a defe
109 We therefore propose that the growth of magnetosome membranes is controlled by a protease-mediat
110 unique feat is accomplished with the help of magnetosomes, nanometer-sized magnetic crystals surround
111 teria are characterized by the production of magnetosomes, nanoscale particles of lipid bilayer encap
114 otactic bacteria, is important in organizing magnetosome organelles into chains that are used for nav
115 iron acquisition, sequestration in dedicated magnetosome organelles, and precipitation into magnetite
116 ferrimagnetic nanocrystals, produced within magnetosome organelles, to align and navigate along the
118 e a diverse group of microorganisms that use magnetosomes, organelles composed of magnetite or greigi
121 Together, these results suggest that the magnetosome precisely coordinates magnetite biomineraliz
123 protein with a protease-independent role in magnetosome protein localization and a protease-dependen
124 ep-wise manner in which membrane biogenesis, magnetosome protein localization, and biomineralization
127 um AMB-1 (AMB-1) contains a second island of magnetosome-related genes that was named the magnetosome
129 e enclosed by membrane invaginations to form magnetosomes so they are able to sense and act upon Eart
130 ain and positioned at midcell by a dedicated magnetosome-specific cytoskeleton, the "magnetoskeleton.
131 e reconciled with the recognition that chain magnetosomes tend to be preferentially extracted in the
132 Magnetotactic bacteria contain chains of magnetosomes that comprise a permanent magnetic dipole i
133 esent in a unique lipid-bound organelle (the magnetosome) that functions as a nanosized reactor in wh
134 ges of the chemical and magnetic features of magnetosomes under certain conditions in different envir
135 is required for the formation of functional magnetosome vesicles and displays a dynamic subcellular
136 um sp. AMB-1 as a model system, we show that magnetosome vesicles exist in the absence of magnetite,
137 embrane-bounded magnetic nanocrystals called magnetosomes via a biologically controlled process.
139 c dipole and nanocrystalline orientations of magnetosomes were also shown to be consistently oriented
141 noparticles (MNPs) within membrane vesicles (magnetosomes), which are embedded with dedicated protein
142 n a membrane-encapsulated vesicle termed the magnetosome, which serves as a specialized compartment t
143 iomineralizing its own anisotropic magnetite magnetosomes, which are aligned in complex aggregations
144 means of intracellular magnetic organelles, magnetosomes, which are aligned into a chain and positio
145 tre-sized, membrane-bound organelles, called magnetosomes, which are tasked with the biomineralizatio
146 n microscopy experiments, both accessing the magnetosomes within intact magnetotactic bacteria and co