ライフサイエンスコーパス: major organ

1 sothelial/serosal/capsular surfaces of every major organ.

2 amine hormones affects the function of every major organ.

3 ow precise delineation and identification of major organs.

4 o quantify the probe uptake in the tumor and major organs.

5 to be taken up by the tumor as well as many major organs.

6 of UPS proteolytic function in virtually all major organs.

7 m of pathological states that affect all the major organs.

8 G biodistribution into interscapular BAT and major organs.

9 ced infiltrates of the bone marrow and other major organs.

10 educe the uptake of the agent into tumor and major organs.

11 ript in the kidney and testis, but not other major organs.

12 survival and decreasing bacterial counts in major organs.

13 led [(124)I]-SHPP-VG76e distributions in the major organs.

14 pathological fibrotic conditions of several major organs.

15 lymphocytic infiltration and destruction of major organs.

16 uced pathology in the lungs but not in other major organs.

17 red treatment for the chronic failure of the major organs.

18 the blood and displayed minimal retention in major organs.

19 scans provided time-activity curves for the major organs.

20 and histopathologic assessments of all other major organs.

21 cluding lung, liver, nasal cavity, and other major organs.

22 consistent histopathological changes in any major organs.

23 sayed the expression of family members in 20 major organs.

24 e pollen and at very low levels in the other major organs.

25 gram was increased more than twofold in the major organs.

26 METH also accumulates extensively in major organs.

27 the entire head and body, in addition to all major organs.

28 rovide information on blood flow patterns in major organs.

29 nfirmed uncontrolled BDBV replication in the major organs.

30 and a decrease in the numbers of bacteria in major organs.

31 66% in the skin without accumulation in the major organs.

32 analysis to be ubiquitously expressed in the major organs.

33 ion in the blood and their distribution into major organs.

34 TTV1, since STTV1 was found in blood and all major organs.

35 ssential functional component of many of the major organs.

36 : perforation, haemorrhage, or infarction of major organs) 24 h or 48 h post-ablation.

37 INPP5E localized to cilia in major organs affected by Joubert syndrome, and mutations

38 The lung is one of the major organs affected in sickle cell disease and the pul

39 sicochemical properties and global uptake in major organs after systemic circulation and biodistribut

40 Major organs, along with the nasal tissue and trigeminal

41 obust mRNA and protein expression within all major organs analyzed (brain, lung, spleen, and kidney).

42 ytes can replace resident macrophages in all major organs and adopt their tissue-specific gene expres

43 All of the major organs and bones were semiautomatically segmented

44 Pathology of the major organs and E1 RNA levels in the liver were also st

45 exposure, reduction in biodistribution into major organs and enhanced tumor exposure in murine tumor

46 ine learning models, we analysed aging in 11 major organs and estimated organ age reproducibly in fiv

47 fit the data, including retention, in three major organs and excretion.

48 n inhibit their target protein expression in major organs and greatly improve the clinical outcome, i

49 Furthermore, high nonspecific uptake in the major organs and persistent background retention results

50 ncipal innate immune cells that populate all major organs and provide the first line of cellular defe

51 determined by monitoring bacterial growth in major organs and recording host survival times.

52 educes the capacity to clear Salmonella from major organs and retards recovery of hematopoietic stem

53 10 broad diagnostic categories involving all major organs and systems.

54 phenotypic differences between species, yet major organs and tissues generally have conserved gene e

55 ic rates (K(i); in kcal . kg(-1 ). d(-1)) of major organs and tissues in adults were suggested by Eli

56 was developed to evaluate the K(i) values of major organs and tissues on the basis of a mechanistic m

57 ed ferroptotic death eliminates cells in all major organs and tissues with imbalanced redox metabolis

58 radiation doses from therapy for total body, major organs and tumors.

59 n 18 of 20 human normal tissues representing major organs, and 55 of 58 (95%) malignant cell lines.

60 Macrophages inhabit all major organs, and are capable of adapting their function

61 t 20-60 min after tracer injection, and BAT, major organs, and blood were extracted, weighed, and mea

62 the animals were sacrificed, and BAT, other major organs, and blood were extracted.

63 y-tissue ratios of more than 5 times for all major organs, and live animal studies demonstrated 65%-9

64 of hematologic parameters, histopathology of major organs, and liver and kidney function tests (ALT,

65 cterial loads below detectable levels in all major organs, and mice appeared otherwise healthy.

66 Cells engraft in major organs, and none of the recipients mount immune re

67 S. and that accumulates in the human plasma, major organs, and ocular tissues.

68 CML24 expression occurs in all major organs, and transcript levels are increased from 2

69 Metastases to other major organs are also suppressed, which can be ascribed

70 ests, complete blood counts, or pathology of major organs are observed from long-term, low-pressure,

71 nd renal clearance with low retention in all major organs at 1, 2, and 4 h after injection.

72 o-intravenous ratios of (18)F-FDG uptake for major organs at 45 min were 1.07 +/- 0.24 for blood, 0.9

73 sion atlas, capturing gene expression in its major organs at different developmental stages.

74 say and an unappreciable chronic toxicity to major organs based on histological analyses.

75 by widespread infiltration of macrophages in major organs causing tissue injury and reduced survival

76 ns in the brain and in select cells of other major organs, challenging the view that 4.1R expression

77 ishing features in clinical presentation and major organ complications that should be recognized.

78 Unlike patients with diseases of other major organs, critically ill patients with ESKD were not

79 with the standard Patlak K(i) in lesions and major organs, demonstrating its quantitative potential a

80 acrophage accumulation nor fibrosis in other major organs despite the presence of higher levels of uP

81 Uptake of (18)F-FDG in most other major organs did not change significantly.

82 for WG-associated SGS and, in the absence of major organ disease activity, should be used without con

83 Major organ disease uniformly associated with increased

84 ck patients, for whom ESKD (compared with no major organ disease) was associated with a 62% (aOR, 1.6

85 ompared with critically ill patients without major organ disease, patients with stroke, cancer, heart

86 ity Score >0, and involvement of one or more major organs, disease-related life-threatening events, o

87 We measured tumor incidence in major organs, DNA mutation rates, DNA mutation spectra,

88 ead to rapid alteration of cellular fitness, major organ dysfunction, and ultimately lethality in mic

89 e older, with a greater prevalence of shock, major organ dysfunction, bacteremia, inflammatory marker

90 fication (ICD-9-CM) codes for septicemia and major organ dysfunction, we identified 8,403,766 patient

91 plant was considered, and had no evidence of major organ dysfunction.

92 performance status of 0 to 2; no significant major organ dysfunction; and at least 3 weeks elapsed si

93 retention of radioactivity in both tumor and major organs except kidney.

94 ing of mice, RA190 distributed to plasma and major organs except the brain and inhibited proteasome f

95 ells contributed significantly to all of the major organs except the lungs.

96 rt surgery in reducing the risk of death and major organ failure.

97 until the occurrence of death or persistent major organ failure.

98 The liver is a major organ for lipid synthesis and metabolism.

99 Skeletal muscle is a major organ for maintaining whole-body energy balance, y

100 Liver was the major organ for removal of circulating nucleosomes, acco

101 Although the kidney is a major organ for vitamin D metabolism, activity, and calc

102 n showing that the liver and kidneys are the major organs for removal of S-ODN and these organs are s

103 Liver is one of the major organs for the detoxification of arsenic.

104 low variability in radiotracer uptake in all major organs for the mouse hotel versus the single mouse

105 ata demonstrate that the liver is one of the major organs for the production of soluble CD14.

106 Major organs from Cdc42GAP(-/-) mice were proportionally

107 nce distinctly different transport among the major organs from that of their d-and dl-counterparts, d

108 sk force, including representatives of all 4 major organs from various AST communities of practice, t

109 inuous blood flow and reduced pulsatility on major organ function have not been studied in detail.

110 th inflammation, fibrosis, coagulopathy, and major organ function were evaluated.

111 patients without substantial derangement in major organ function.

112 The larvae develop rapidly, with all major organs having developed by 5-6 days post-fertiliza

113 The kidney was identified as a major organ in catabolism of Lp B-70.5 in New Zealand wh

114 as the highest Smad baseline activity of any major organ in the mouse, and we now demonstrate that th

115 f view (AFOV) of 106 cm, enabling imaging of major organs in 1 bed position.

116 ression of this gene was detected in all the major organs in adult animals.

117 Lipid extraction of the tumors and major organs in both animal models showed the sole prese

118 No obvious abnormalities were found in major organs in hepsin-/- mice in histological examinati

119 ale single-cell profiling of VSNs from seven major organs in mice using multiplexed projection barcod

120 ssive iron storage that results in damage to major organs in the body.

121 n and is differentially expressed in the two major organs in the human body, liver and skin.

122 neutrophil and eosinophil migration through major organs in vivo are fundamentally different, with t

123 ause for progressive degenerative disease of major organs in which affected individuals benefit from

124 onization of the brain, and also invaded the major organs, in line with increases in the severity of

125 ized uptake values (SUV) were calculated for major organs including brain, heart, lungs, liver, kidne

126 levels in the serum, peritoneal cavity, and major organs including the kidney and heart.

127 NV accumulated in major organs, including bone marrow and brain, known san

128 in nonclinical studies to be distributed to major organs, including the brain, bringing about system

129 in mice resulted in EGCG accumulation in all major organs, including the brain.

130 ntibody inhibited Raji cell dissemination to major organs, including the central nervous system, and

131 The tissues of major organs, including the lung, liver, kidney, and spl

132 Here, we discuss the major organs involved in energy metabolism in Drosophila

133 The liver and kidneys were the major organs involved in uptake and removal of S-ODN.

134 corticosteroids as a cornerstone therapy for major organ involvement in childhood SLE, potential comp

135 ecome the gold standard for the treatment of major organ involvement in systemic lupus erythematosus.

136 ients were significantly more likely to have major organ involvement such as renal disease (P < 0.000

137 lmonary function tests and other measures of major organ involvement were stable.

138 of an approach for estimating doses to other major organs is crucial.

139 ake is VEGFR-mediated, whereas uptake in all major organs is not affected by blocking within the marg

140 y expressed in the maturing epithelia of all major organs, localizing to cell membranes.

141 (7) PFU/ml) viral loads were detected in all major organs (lung, liver, spleen, kidney, brain, etc.)

142 to the same level of stationary infection in major organs, mice infected with the Ravenel strain died

143 The bone marrow (BM) is a major organ of breast cancer (BC) dormancy and a common

144 Although, as the major organ of gas exchange, the lung is considered a no

145 expressed primarily within the intestine, a major organ of metabolic and endocrine control, distinct

146 biota is frequently considered an additional major organ of the human body and exerts profound immuno

147 The cereal endosperm is a major organ of the seed and an important component of th

148 Gene sequence and expression data from four major organs of A. amnicola provide novel basal informat

149 pid, with liver and kidneys representing the major organs of accumulation.

150 nes were analyzed for expression profiles in major organs of Arabidopsis plants.

151 AtECA1 to AtECA4, which are expressed in all major organs of Arabidopsis.

152 oth AtVTI1a and AtVTI1b are expressed in all major organs of Arabidopsis.

153 The 1.5-kb TTG1 transcript is present in all major organs of Arabidopsis.

154 Previously, we have shown that, in major organs of both mouse and man, G3 subunit expressio

155 o the liver, kidney, and pancreas, the three major organs of DHBV replication.

156 s were also measured from excised tumors and major organs of euthanized animals.

157 rapidly visualizing transgene expression in major organs of intact live mice that is simple, rapid,

158 P polymerase chain reaction (PCR) in all the major organs of many chimeric mice and visualized in chi

159 hern blots detected kidney and testis as the major organs of RHCG or Rhcg expression.

160 at the host-environment interface and around major organs of the body and produce specific mediators

161 e cancer cells already started affecting the major organs of the body such as lung, liver, spleen, ki

162 gulate mineralization, and is found in other major organs of the body, namely the kidney, brain, live

163 absorption and excessive iron deposition in major organs of the body.

164 n was significantly higher than in any other major organs of the body.

165 As one of the major organs of the excretory pathway, the kidneys repre

166 he tumor site and were not observed in other major organs of the mice, indicating unique tumor specif

167 respiratory tract and systemic spread to all major organs of the mice, resulting in fatal septicemia.

168 ics approach, we present a TF network in the major organs of the mouse, allowing data mining and gene

169 designated AGK1, and is expressed in all the major organs of the plant.

170 veral minor transcripts were detected in all major organs of the plants.

171 gfp expression in specific cell types of all major organs of the rice plant.

172 ding the abdominal wall after removal of the major organs, of wild type, Pitx2 heterozygote and mutan

173 Clinically significant major organ or cumulative toxicities were rare.

174 accumulation, with concurrent clearance from major organs over a period of 72 h.

175 uations confirmed the absence of toxicity in major organs, reinforcing the safety profile of this app

176 In conclusion, although the liver is the major organ responsible for acetaldehyde metabolism, a c

177 evels of expression in the normal liver, the major organ responsible for blood clearance of adenoviru

178 Although muscle is the major organ responsible for insulin-stimulated glucose d

179 The liver was the major organ responsible for plasma clearance, accounting

180 ete apo A-IV, but the small intestine is the major organ responsible for the circulating apo A-IV.

181 ss and size of the skull, brain, and several major organs, show significant bidirectional seasonal ch

182 Histologic analysis of all major organs showed no abnormal proliferation of human c

183 onary vascular endothelial cells and lung, a major organ site for tumor metastasis.

184 y using SEER data, the incidence of GISTs in major organ sites increased in the last 2 decades among

185 For all major organ sites, male and female, we use 1979 to 2003

186 Second, the gene expression profiles reflect major organ-specific functions on the molecular level, i

187 heir target protein expression by 18%-61% in major organs such as liver, heart, and kidney.

188 brain, and were non-toxic to brain and other major organs, such as kidney, lung, liver, and spleen, a

189 he most important contributor to IHM for the major organ surgeries studied.

190 d tissue injury in the liver and kidney, two major organs susceptible to LPS toxicity.

191 by smoking status after adjustment for age, major organ system disease, family history of CHD, and B

192 of evaluation, clinical and laboratory data, major organ system dysfunction, 48-hr patient status, an

193 d toward an increased number of days free of major organ system failures and a significant reduction

194 5HT) signaling regulates processes in every major organ system, but it is most widely known for its

195 s numerous biological functions within every major organ system.

196 greater 10-year cumulative incidences of all major organ-system outcomes versus the general populatio

197 ssense mutations, and the involvement of all major organ systems (central nervous system, thyroid, br

198 include amyloid involvement of more than two major organ systems and predominant cardiac involvement.

199 e and survive in expected numbers, and their major organ systems are normal.

200 Because major organ systems are variable in their functions and

201 ins and are required for construction of all major organ systems during embryogenesis.

202 f sepsis-induced gene expression patterns in major organ systems including lung, liver, kidney, thymu

203 unctionally crippling lesions within various major organ systems of experimental NHPs.

204 terns in 60 distinct tissues representing 11 major organ systems of inbred line B73.

205 ontains quantitative transcript data for all major organ systems of switchgrass throughout developmen

206 ides a global view of gene expression in all major organ systems of this species, with special emphas

207 tinct anatomic niches both within and across major organ systems shapes TRM identity and examine mech

208 h help to regulate the physiology of all the major organ systems within higher eukaryotes.

209 aning age due to severe inflammation in most major organ systems, but the mechanism underlying this d

210 gressed to invasion of the pathogen into all major organ systems, including the brain.

211 re no discernible derangements in any of the major organ systems, including the forebrain.

212 d not discern any derangements in any of the major organ systems, including the nervous system, which

213 Among cancers of all major organ systems, only the incidence of hematopoietic

214 riptase and HAI-1 in epithelial cells of all major organ systems, thus strongly supporting a role of

215 besity has pathophysiologic effects upon all major organ systems.

216 causes a range of pathologic effects on all major organ systems.

217 ensive tissue nitros(yl)ation throughout all major organ systems.

218 ults in a massive ischemic insult to several major organ systems.

219 ) help to regulate the physiology of all the major organ systems.

220 significant adverse effects were observed on major organ systems.

221 ak differentiate into the precursor cells of major organ systems.

222 rointestinal tract which then translocate to major organ systems.

223 cts of exposure to tobacco smoke across most major organ systems.

224 injuries and medical complications affecting major organ systems.

225 The liver is a major organ that controls hepatic and systemic homeostas

226 The thymus is a major organ that generates "natural" CD4+CD25+ T regulat

227 The discovery of the placenta as a major organ that generates HSCs and maintains them in an

228 The liver is a major organ that stores RA suggesting that retinoids pla

229 both adipose tissue and skeletal muscle, two major organs that are critical for maintaining energy ho

230 The major organs that remove RIT were identified by live mou

231 bacteria occurs in the liver and spleen, the major organs that remove these bacteria and their lipopo

232 Of the major organs, the highest radionuclide uptake at 1, 2, a

233 Of the major organs, the highest uptake at 1, 2, and 3 h after

234 Given the absence of toxicity to major organs, the minimal myelosuppression or immunosupp

235 action of (111)In-administered activity in 7 major organs, the whole body, and remainder tissues over

236 to predict biodistributions in primates, in major organs, these results in mice and monkeys were sim

237 ) without causing significant weight loss or major organ tissue degeneration.

238 not accompanied by noticeable weight loss or major organ tissue degeneration.

239 bi in terminal arterioles and capillaries of major organ tissues in these mice that were either eutha

240 composition, blood chemistries, condition of major organs, tissues and relevant cell types, behavior,

241 ysis of tissue from the kidney and all other major organs to establish the distribution of the virus

242 o evidence of hemorrhage, anemia, or AVMs in major organs to explain the reduced aortic pressure.

243 Although major organ toxicities frequently arise in patients trea

244 al blood transfusion was associated with all major organ transplants, compared with no transfusion.

245 lications were predominantly associated with major organ transplants.

246 combination of bacterial enumeration in the major organs, two-dimensional bioluminescence imaging, a

247 nctive set of tissue-specific oncotargets in major organs upon (56)Fe (600 MeV/amu; 0.5 Gy/min; 0.8 G

248 The ratio of IsoFs to IsoPs in major organs varies according to normal steady-state tis

249 ferences in growth, numbers of metastases to major organs, vascularity, and perfusion between SU5416-

250 e categorized transplants according to type (major organs versus superficial tissues).

251 selected time points, and FAPI uptake in the major organs was measured ex vivo.

252 ents, including those with diseases of other major organs, we investigated DNR orders on admission to

253 No gross or microscopic abnormalities of major organs were associated with oral colonization of r

254 ora isolate, and tissue samples from various major organs were collected from dams and fetuses for th

255 Residence times for (90)Y in blood and major organs were estimated from (111)In biodistribution

256 All major organs were examined grossly and histologically af

257 Disseminated microabscesses in major organs were found in animals treated with combinat

258 r, the peritoneal cavity was lavaged and the major organs were harvested for culture.

259 Systemic distribution and activity in major organs were low.

260 urinary excretion, and no specific uptake in major organs were observed in 24 h.

261 ion is predominantly in skin, one of the two major organs where type I collagen is expressed.

262 e deposition of both dextran and Doxil(R) in major organs with a concurrent increase in plasma and tu

263 ults: High (11)C-PS13 uptake was observed in major organs with high COX-1 density, including the sple