ライフサイエンスコーパス: male mice

1 sociated with thinner cortical bone in adult male mice.

2 ereas these drastic changes did not occur in male mice.

3 using an operant temporal production task in male mice.

4 oves metabolic parameters and slows aging in male mice.

5 umorigenic niche in the livers of Ncoa5(+/-) male mice.

6 ver steatosis in high-fat diet (HFD)-treated male mice.

7 pinephrine reuptake inhibitor venlafaxine in male mice.

8 Females were caged with male mice.

9 during food-seeking and food consumption in male mice.

10 and key mediators for mating and fighting in male mice.

11 ill S. aureus ex vivo compared with those of male mice.

12 ne neurons to auditory-cued fear learning in male mice.

13 was almost exclusively seen in group-housed male mice.

14 strocytes, leads to autism-like behaviors in male mice.

15 s significantly higher in female compared to male mice.

16 ely normalized the tumor burden in castrated male mice.

17 Similar results were observed in intact male mice.

18 redictor of lifetime stress vulnerability in male mice.

19 conditioned place preference (CPP) in adult male mice.

20 ranches of these neurons in C57/Bl6 Thy1-YFP male mice.

21 1e1 induction in the kidney occurred only in male mice.

22 ns, thereby governing aggressive behavior in male mice.

23 signs of increased anxiety in female but not male mice.

24 nother major prostaglandin, PGE(2), than did male mice.

25 FL) impairs, hippocampal-dependent memory in male mice.

26 te sodium (AOM/DSS)-induced tumorigenesis in male mice.

27 e a gene that is highly enriched in ECs from male mice.

28 omotor activity and normal sleep patterns in male mice.

29 mproves motor functions in dopamine-depleted male mice.

30 cial effects of L. reuteri on bone health in male mice.

31 of monoaminergic axons in female, but not in male mice.

32 genetic approaches to disrupt this enzyme in male mice.

33 ductive tract were housed with unmanipulated male mice.

34 spectively, with no effect on sexually naive male mice.

35 ity-induced insulin resistance compared with male mice.

36 owing cocaine or food self-administration in male mice.

37 on and improved glucose tolerance in znt7-KO male mice.

38 ctivity persisting into the chronic phase in male mice.

39 of partial damage adjacent to the infarct in male mice.

40 CCSNs induced by peripheral axonal damage in male mice.

41 by TLR9 antagonism or Tlr9 mutation only in male mice.

42 glycemia, and liver steatosis in HFD-treated male mice.

43 nd assessed their temporal dynamics in awake male mice.

44 rom female mice and about 150% (p < 0.05) in male mice.

45 inking across a binge-drinking experience in male mice.

46 points after contextually fear conditioning male mice.

47 rogressively disrupts glucose homeostasis in male mice.

48 ice, consistent with our earlier findings in male mice.

49 behavioral choice, and reward information in male mice.

50 rformed in GRP::cre and GRP::eGFP transgenic male mice.

51 ound hearing loss in female mice compared to male mice.

52 technique of positron emission tomography in male mice.

53 cauda epididymis, leading to infertility in male mice.

54 d motor coordination during pole climbing in male mice.

55 difference in lean body mass was detected in male mice.

56 aeffer-collateral pathway in both female and male mice.

57 and Smad158;Alb-Cre(+) female compared with male mice.

58 g knockout (lack mature T and B lymphocytes) male mice.

59 cade, on cocaine self-administration (SA) in male mice.

60 cAMP and reduction in spike accommodation in male mice.

61 LM is TNFR2-dependent in female, but not in male mice.

62 essing at least DRG Kcna2 gene expression in male mice.

63 a in the hippocampus of cognitively impaired male mice.

64 ntified cerebellar nuclei neurons in vivo in male mice.

65 and 3) manipulation increases aggression in male mice.

66 equently reduced HCC incidence in Ncoa5(+/-) male mice.

67 and for pairing of homologous chromosomes in male mice.

68 s and estrogen-DNA adducts in female but not male mice.

69 ion therapeutically in the brains of APP/PS1 male mice.

70 n female mice, it had the opposite effect in male mice.

71 without affecting basal neurotransmission in male mice.

72 ration, only reduces macrophage expansion in male mice.

73 othalamus to improve metabolic parameters in male mice.

74 significantly reduced by Keap1 deficiency in male mice.

75 cle (ZT14 and ZT21) from adult (12-18 weeks) male mice.

76 d bone mass by regulating bone remodeling in male mice.

77 osterior parietal cortex (PPC) in adolescent male mice.

78 hepatic gluconeogenic enzymes in female and male mice.

79 e of BMN were higher in female compared with male mice.

80 eneficial metabolic effects of 17alpha-E2 in male mice.

81 P2 antagonism blocks monocyte brain entry in male mice.

82 leads to a reduction in Abeta deposition in male mice.

83 nge-like ethanol drinking in female, but not male, mice.

84 nical hypersensitivity in female, but not in male, mice.

85 t of hyperalgesic priming in female, but not male, mice.

86 nge-like alcohol drinking by female, but not male, mice.

87 for hyperalgesic priming in female, but not male, mice.

88 (35%) than females mated with sham-infected male mice (0%) were infertile (P < 0.05).

89 PMUCs isolated from male mice (14-16 weeks) were used for live-cell fluoresc

90 Aged male mice (18-20 months) were subjected to ischemic stro

91 We found that, in male mice, 2 weeks of social isolation immediately follo

92 ore females mated with C. muridarum-infected male mice (35%) than females mated with sham-infected ma

93 nje cells in cerebellar slices prepared from male mice ~48 h after they learned a delay eye-blink con

94 Our studies demonstrate that, in male mice, a history of chronic binge alcohol-drinking e

95 , and optogenetic approaches to establish in male mice, a wiring chart between the insula cortex (IC)

96 s (NAc), a key brain reward region, of adult male mice after cocaine administration.

97 urons causes decreased sucrose preference in male mice after subchronic variable stress, whereas DREA

98 lls, and increased susceptibility of old and male mice, all features of IPF.

99 e Lrp4 gene augmented Abeta plaques in 5xFAD male mice, an AD mouse model, and exacerbated the defici

100 sociated with the chronic phase of stroke in male mice and both genders of humans.

101 e X-zone that should disappear at puberty in male mice and during the first pregnancy in female anima

102 Adult male mice and hippocampal brain slices.

103 ss for the opportunity to attack subordinate male mice and relapse to aggression seeking during absti

104 with (2S,6S)-HNK attenuating learned fear in male mice, and (2R,6R)-HNK preventing stress-induced dep

105 ively correlated with liver triglycerides in male mice, and Mogat1 and Cd36 expression were positivel

106 ns in the central nucleus of the amygdala of male mice are activated by in vivo ethanol consumption a

107 e demonstrated that macrophages derived from male mice are intrinsically more migratory.

108 We report that Tug1-knockout male mice are sterile with underlying defects including

109 xamined the strategies adopted by female and male mice as they learned the value of stimuli that vari

110 AdipoR1 in 5-HT neurons induced anhedonia in male mice, as indicated by reduced female urine sniffing

111 nimise aggressive behaviour in group-housed, male mice based upon the results of the study and taking

112 Male mice became overtly diabetic at ~5 weeks of age, wh

113 Although male mice brains demonstrated an increase in CD36 protei

114 g an inhibitor rescues cognitive deficits in male mice but has no effect on female mice.

115 e1 knockout mice abolished the protection in male mice but not in female mice, indicating that Sult1e

116 upregulated in both DRN projection fields of male mice but only in the mPFC of female mice.

117 bitor AT-56 caused intense pain behaviors in male mice but was only effective at high doses in female

118 el to analyze the within-a-cage hierarchy in male mice, but also as a paradigm of novel territorial c

119 nds exchange during meiotic recombination in male mice by analyzing patterns of heteroduplex DNA in r

120 sensitivity to alcohol-aversion exhibited by male mice can be mimicked by the local inhibition of ERK

121 ICH induction in male mice caused profound HN loss in the affected hemisp

122 l contacts and corneal edema, in female than male mice, characteristic of late-onset FECD.

123 In male mice, compared with their age-matched littermate WT

124 Nests from cages of group housed male mice contain a variety of proteins that primarily o

125 essed by X-gal staining in R6/2-OPN4(Lacz/+) male mice, contributed to the diminished light-induced c

126 The treatment led to male mice developing accelerated diabetes.

127 conditional genetic ablation of gp78/AMFR in male mice disrupts P450 ERAD, resulting in statistically

128 erformed ventral neck surgery in 21 C57BL/6J male mice, divided into two groups: Unilateral RLN Trans

129 Technicians observed group-housed, male mice during daily routine cage checks and recorded

130 llularly from CA2 pyramidal neurons (PNs) in male mice during social behavior.

131 ngthened displays of aggressive behaviors by male mice during the resident intruder paradigm.

132 However, in AOM/DSS-treated male mice, E2 supplementation showed significantly lower

133 uprizone and rapamycin (Cup/Rap) in C57BL/6J male mice efficiently demyelinated and remyelinated the

134 optic nerve head was measured in 8-week-old male mice every 2 weeks until age 20-week.

135 GluN2D(-/-) male mice exhibit evidence of exacerbated negative emoti

136 the BNST, we find that BNST-GluN2D(flx/flx) male mice exhibit increased depressive-like behaviors, a

137 teroid levels in the circulation, TRPM8(-/-) male mice exhibit increased mounting frequency indiscrim

138 of single CA2/CA3 neurons from freely-moving male mice, exploring a familiar environment.

139 gical recordings of single units in behaving male mice exposed to a rat to investigate the encoding o

140 minogen inhibitor-1 (PAI-1) was increased in male mice expressing the Swedish mutation of the amyloid

141 We previously determined that male mice fed a high-fat diet exhibit macrophage infiltr

142 iver was also altered in myonectin-deficient male mice fed an HFD.

143 Notwithstanding these defects in male mice, females were resilient to OFC (but not hippoc

144 c of stress-susceptible and stress-resilient male mice following 10 d of CSDS.

145 significant dendritic spine loss observed in male mice following irradiation is microglia complement

146 cutely prepared brain slices from female and male mice following METH-associated learning as a readou

147 edial prefrontal cortex (mPFC) during SWS in male mice following repeated learning trials in a weakly

148 Female and male mice from 18 CC strains were evaluated using a mult

149 449 male mice from 33 inbred strains underwent MCAO for 6 ho

150 In male mice, genetic ablation of Pramef12 arrests spermato

151 Additionally, male mice had greater CD36 mRNA expression than females

152 Elafin-overexpressing HFD-treated male mice had increased serum leptin levels, and serum e

153 le mice had only intracellular pathology and male mice had less pathology, particularly in the dorsal

154 All C. muridarum-inoculated male mice had positive urine cultures.

155 hen stressed with an HFD, myonectin-knockout male mice had significantly elevated VLDL-triglyceride (

156 To address this, we have used male mice harboring an inactivating mutation of mitogen-

157 Wild and laboratory male mice have been shown to develop linear hierarchies,

158 the orthologous Q140K Abcg2 variant and find male mice have significant hyperuricemia and metabolic a

159 were performed in the following 12-week-old male mice: (i) NK1R(-/-); (ii) Mdr2(-/-); and (iii) NK1R

160 nstrated that PCB-77 administration to obese male mice impaired glucose tolerance during weight loss.

161 demyelination, showed that PAR1 knock-out in male mice improves replenishment of myelinating cells an

162 Here, we trained adult male mice in a cortex-dependent auditory discrimination

163 Male mice in which Nell2 had been knocked out were infer

164 n, we observed that DA neurons in female and male mice in which VGluT2 was conditionally removed esta

165 ual cortex (V1) of awake, passively behaving male mice increase as a function of arousal and are larg

166 the medial prefrontal cortex (mPFC) of adult male mice induces depressive-like behaviors.

167 Here, we assessed the sleep architecture of male mice infected with T. brucei and found that infecte

168 fecal microbiota from age-matched APPPS1-21 male mice into ABX-treated APPPS1-21 male restores the g

169 ation of excitatory/inhibitory balance in KO male mice is most likely responsible for impaired sociab

170 hibition of GABA interneurons in the mPFC of male mice is sufficient to produce antidepressant action

171 s the basal levels of depressive behavior in male mice, it reduces in female mice evoked-depression o

172 e whether subchronic 7-day CORT treatment of male mice just prior to mating would be sufficient to in

173 Here we report that male mice knock-out (KO) for Ophn1 display hippocampal e

174 While microglia in brain slices from male mice lack C3aR1 receptors, both receptors are expre

175 However, the phenotype of male mice lacking Dax1 is strain-dependent due to the ba

176 In male mice lacking HELLS, DSBs are retargeted to other si

177 Male mice lacking myonectin, however, had reduced physic

178 BP (using 24-hour telemetric monitoring) in male mice lacking slc26a6 (a transporter that inhibits t

179 Male mice lacking sperm-specific calcineurin (PP2B), a c

180 Strikingly, mutant male mice lacking the p75 neurotrophin receptor (p75(NTR

181 Mimicking this decrease in young adult male mice led to age-like memory deficits in hippocampus

182 n days), we performed proteomic profiling of male mice liver with quantitative liquid chromatography

183 Macrophages from male mice maintained migratory capacity when cultured wi

184 Male mice Mus musculus fed a high-fat diet rich in SFAs

185 Virgin male mice naturally kill another male's pups so they can

186 Here, we show that in castrated male mice, neutrophil maturation and function are impair

187 In juvenile male mice, NMDAR ablation results in several pathophysio

188 In male mice, nPM exposure increased food intake, body weig

189 Aggression in male mice often leads to injury and death, making social

190 xcitability of PDYN neurons was increased in male mice only.

191 the first phase of the formalin test, but in male mice only.

192 9-/- female mice, but not in aged Tmprss9-/- male mice or younger adult Tmprss9-/- mice in both sexes

193 In this study, we showed that, in male mice, orexin neurons in the lateral hypothalamus ac

194 ricular nucleus of the hypothalamus (PVH) of male mice (OT-Ires-Cre) enhanced social investigation du

195 lation of Fos expression in hippocampus from male mice overexpressing SORLA by RNAseq analysis.

196 rozygous deletion of Il-6 gene in Ncoa5(+/-) male mice partially improved spermatozoa motility and mo

197 We found that in Cc2d1a-deficient male mice PDE4D is hyperactive, leading to a reduction i

198 distinct patterns of vocalization emerge as male mice perform specific social actions.

199 s stress-induced depressive-like behavior in male mice, perhaps by altering alpha-amino-3-hydroxy-5-m

200 Here we show that male mice, pigs, goats, and cattle harboring knockout al

201 t image-value associations more quickly than male mice, preferring a fundamentally different strategy

202 e present study, we have found that in adult male mice, prefrontocortical PV+ cells surrounded by PNN

203 In neurons of adult male mice pretreated with LPS, the number of action pote

204 tight junction protein claudin-5 (cldn5) in male mice, promoting passage of circulating proinflammat

205 In terms of ethanol response, KI alpha2 male mice recovered faster from the administration of at

206 Chemogenetically activating LJA5 neurons in male mice reduces capsaicin-induced pain and histamine-i

207 y cell content were comparable in lesions in male mice regardless of Fap status.

208 g(-1) for female and 100 +/- 6 mg.kg(-1) for male mice, respectively.

209 and circadian gene expression in female and male mice, respectively.

210 show that the primary visual cortex (V1) of male mice responds to Kanizsa illusory contours.

211 erestingly, ablation of Bin1 in microglia of male mice resulted in significant reduction in the expre

212 Global deletion of Tiam1 in male mice results in DG granule cells with simplified de

213 ), as measured in whole-cell recordings from male mice running in virtual corridors (Domnisoru et al.

214 Here, we report that CD38(-/-) male mice show an abnormal cortex development, an excita

215 beta4 knock-out (KO) male mice show increased novelty-induced locomotor activ

216 and females both represent sex in the dmPFC, male mice show stronger encoding of female cues, and the

217 neurons and the regulation of aggression in male mice.SIGNIFICANCE STATEMENT Aggression is a behavio

218 CFA supplementation in the drinking water of male mice significantly improved recovery of affected li

219 After the mitosis-to-meiosis transition in male mice, specific ERVs function as active enhancers to

220 t with this finding, Ghrl(-/-) and Ghsr(-/-) male mice studied after either 6 or 16 h of fasting had

221 Similar effects were seen in male mice subjected to RYGB at 5-6 weeks, although growt

222 Preclinical studies in male mice suggest that activity of ventral hippocampus (

223 was greatly reduced compared with those from male mice, suggesting CR3-dependent differences in bacte

224 y did not attenuate HU-induced osteopenia in male mice, suggesting that leptin is not required for bo

225 inhibitor, observed in conditional knockout male mice supports deficient 5-HT transmission underlyin

226 In male mice, territorial and infant-directed aggression ar

227 Here we show in male mice that associative fear learning potentiates syn

228 VTA DA neurons were identified using DAT-Cre male mice that carried an optrode with minimal impact on

229 inding is corroborated in stress-susceptible male mice that have undergone chronic social defeat stre

230 multiciliogenesis, including Foxj 1 and Ccno Male mice that lacked Gemc1, Mcidas or Ccno were found t

231 modulation pathway within the hippocampus of male mice that promotes memory consolidation.

232 tivator of transcription-5 (pSTAT5) in adult male mice that received an intraperitoneal GH injection.

233 ch to test this hypothesis in adult C57BL/6J male mice that received vehicle or Delta9-THC in escalat

234 ansporter (vGAT) and gephyrin, in the NAc of male mice that underwent chronic social defeat stress (C

235 early life exposure using chow-fed C57BL/6J male mice that were exposed to real-world inhaled, conce

236 that, in HD mouse models (R6/2 and N171-82Q male mice), the expression of melanopsin was reduced bef

237 We found that, in hippocampal neurons of male mice, the BAD-BAX-caspase-3 pathway regulates autop

238 of fasting-induced torpor in both female and male mice, their effects on thermoregulation and torpor

239 SCN rhythmicity in these temporally chimeric male mice thus enabled us to determine the contribution

240 Here, we exposed wild-type male mice to 5-60 min of 40 Hz or control flicker and as

241 We 1) exposed adult male mice to an odor, acetophenone (Ace) or Lyral (paren

242 We found that co-exposure of male mice to saccharin and nicotine produced significant

243 ve way, here we exposed 6-month-old C57BL/6J male mice to whole-body space radiation and subsequently

244 AAV vector serotype PHP.B in adult wild-type male mice transduced neurons and astrocytes throughout t

245 We have previously shown that in male mice transient blockade of NMDA receptors (NMDARs)

246 Cdkl5 knockout male mice treated with isoform 1 via intrajugular inject

247 Both HFD female and HFD male mice treated with oestradiol also displayed strikin

248 We also studied HFD male mice treated with oestradiol or vehicle.

249 th authentic and transmitted stress in adult male mice trigger metaplastic facilitation of long-term

250 TAF4b-deficient male mice undergo a complex series of developmental defe

251 When male mice underwent atorvastatin and pravastatin adminis

252 We found that, in male mice, upregulation and downregulation of SOM-IN mTO

253 ns of the aIC projecting to the BLA in adult male mice using a retro-AAV construct and assessed their

254 ion, by detecting DA in striatal slices from male mice using fast-scan cyclic voltammetry in the abse

255 llular and parvocellular oxytocin neurons in male mice, validated across anatomical, projection targe

256 We found that colitis in male mice was ameliorated by CMPs and large chitin beads

257 istration of a slow-pressor dose of AngII in male mice was associated with transcriptional and post-t

258 The number of M1 ipRGCs in R6/2 male mice was reduced due to apoptosis, whereas non-M1 i

259 ) readily crossed the blood-brain barrier in male mice, was taken up by brain regions and entered the

260 the anterior cingulate cortex (ACC) of adult male mice we found good coupling, particularly of slow s

261 Using Drd1-Cre mTOR-conditional knockout male mice, we combined behavioral, biochemical, electrop

262 ts in superficial layers of V1 in female and male mice, we demonstrate that 14 d MD during the critic

263 Here, by using male mice, we demonstrate that the metabotropic P2Y(1) r

264 s along the dorsal CA1-DG axis from sleeping male mice, we detected and classified two types of LFP e

265 ion of Cdk5 regulates stress responsivity in male mice, we hypothesized that such a mechanism may be

266 genetic and pharmacological manipulations in male mice, we show that the presence of noradrenaline in

267 Using a stroke model in male mice, we showed that stroke was followed by a trans

268 Using male mice, we tested whether Fragile X Mental Retardatio

269 Both plasma and brain metabolites in male mice were altered following a single peripheral LPS

270 Liver tumors in male mice were enriched in pathways and gene signatures

271 these measures were observed when adolescent male mice were exposed to concomitant ketamine and socia

272 Male mice were exposed to mild head impacts daily for 20

273 In the present study, male mice were fed a low-fat diet (LFD, 10% kcal), HFD (

274 BALB/c male mice were fed either standard chow diet or Western-

275 Ten week old adult C57BL/6 male mice were flown aboard the ISS for 35 days and retu

276 ment a horizontal sexual transmission model, male mice were inoculated in the meatus urethra with Chl

277 Hearts from aged (18-20 months) male mice were isolated at ZT4 and ZT14.

278 Finally, C5ar1(-/-) male mice were largely protected from histamine-induced

279 Conversely, male mice were more likely to be inconsistent, changing

280 Male mice were nearly as effective as female mice at red

281 Forty C57BL/6, male mice were randomized into the following groups: (1)

282 The male mice were then transferred to cages holding 'recipi

283 Male mice were trained to localize a pole using a single

284 C57BL/6 male mice were treated with broad-spectrum antibiotics f

285 Only male mice were used in this study.

286 upregulated only in macrophages derived from male mice when cultured in the presence of FFA to mimic

287 al gray (PAG) that are transiently active in male mice when they produce ultrasonic courtship vocaliz

288 al social competition between two unfamiliar male mice, whereas final social status acquired within a

289 l neurons in astrocyte-specific ephrin-B1 KO male mice, which coincided with a greater vGlut1/PSD95 c

290 were undertaken in these obese adult C57BL/6 male mice, which indicated impaired hepatic gluconeogene

291 increases neuroendocrine stress responses in male mice, while the same treatment increases hyponeopha

292 Using male mice with a mutation in MSK1, we show that MSK1 is

293 d that treatment of diet-induced obese (DIO) male mice with adropin(34-76) (the putative secreted dom

294 Here we show that treatment of male mice with BPA (50 ug/kg/day) during 8 days, decreas

295 Using male mice with Cre-recombinase directed to the oxytocin

296 Non-diabetic and Akita/+ male mice with different duration of diabetes were subje

297 Here, we report that male mice with global heterozygous loss of cacna1c exhib

298 striatum, and ventral striatum of female and male mice with green fluorescent protein-tagged D1 or D2

299 cotine withdrawal in male Wistar rats and in male mice with neuron-specific PPARgamma deletion (PPARg

300 from the habenulo-interpeduncular circuit of male mice withdrawn from chronic nicotine treatment.