ライフサイエンスコーパス: male sterility

1 n about the mechanisms underlying stress and male sterility.

2 and reduction of its levels correlates with male sterility.

3 ellular bridges in all germ cells and causes male sterility.

4 with pollen production and results in plant male sterility.

5 ependent incompatibilities that cause hybrid male sterility.

6 koencephalopathy in multiple brain areas and male sterility.

7 position and subsequently collapsed, causing male sterility.

8 tin degeneration of germ cells, resulting in male sterility.

9 ci for both behavioural isolation and hybrid male sterility.

10 sis, spermatid individualization, and causes male sterility.

11 global chromatin status, leading to complete male sterility.

12 hich displayed maternal-effect lethality and male sterility.

13 s the most likely mechanism producing hybrid male sterility.

14 M. musculus X chromosome involved in hybrid male sterility.

15 e phenotype, producing stable, nontransgenic male sterility.

16 on between species by contributing to hybrid male sterility.

17 ric ORFs are candidate genes for cytoplasmic male sterility.

18 tion in male reproductive organs, leading to male sterility.

19 (hms2) locus to cause nearly complete hybrid male sterility.

20 nding to nematode proteins, 37% (7/19) cause male sterility.

21 rescues sDMA modification of Sm proteins and male sterility.

22 at targeted mutation of the Tenr gene causes male sterility.

23 ich accounts for the microspore abortion and male sterility.

24 stamen development that results in complete male sterility.

25 sive gene expression, delayed flowering, and male sterility.

26 togonia to differentiate, resulting in adult male sterility.

27 ble and the only observed defect is complete male sterility.

28 m for genetic factors contributing to hybrid male sterility.

29 al structure and functions, hypotension, and male sterility.

30 , almost there (amo), caused nearly complete male sterility.

31 and block sperm maturation in vivo, causing male sterility.

32 bit reduced lifespan, locomotor defects, and male sterility.

33 lock the pathway of JA synthesis result into male sterility.

34 nts exhibit defective spermatogenesis and/or male sterility.

35 s, resulting in failed microsporogenesis and male sterility.

36 and the restoration of Texas cytoplasm-based male sterility.

37 l known selfish genetic element, cytoplasmic male sterility.

38 , which is necessary for T cytoplasm-induced male sterility.

39 express novel mitochondrial genes that cause male sterility.

40 al protein necessary for T cytoplasm-induced male sterility.

41 ural defects and functions, hypotension, and male sterility.

42 nd genetic mechanisms underlying t haplotype male sterility.

43 0 Mb of DNA but has only six loci mutable to male sterility.

44 ption causes renal atrophy, hypotension, and male sterility.

45 ecause homozygosity of the distorters causes male sterility.

46 levant to the meiotic drive theory of hybrid male sterility.

47 ntional myosin, 95F myosin, which results in male sterility.

48 unctions in the point mutants, that leads to male sterility.

49 anther-specific Ms2 activation that confers male sterility.

50 me translocations (T(Y;A)) to cause complete male sterility.

51 us thymidine kinase, which is known to cause male sterility.

52 sis, prevents spermiogenesis, and results in male sterility.

53 n and testosterone production and results in male sterility.

54 utant flies exhibit complete azoospermia and male sterility.

55 ent stages are affected, leading to complete male sterility.

56 s (BnMS5(b) and BnMS5(d) ) that could induce male sterility.

57 Taf1 contribute about equally to HMS1 hybrid male sterility.

58 One of the most common HIs is male sterility.

59 n, resulting in pollen abortion and complete male sterility.

60 contradictory observations exist for hybrid male sterility.

61 6 in mice leads to acephalic spermatozoa and male sterility.

62 d flower development, delayed flowering, and male sterility.

63 ion of a phytotoxic barnase and provides for male sterility.

64 al differentiation and resulted in increased male sterility.

65 Gnat3(-/-) doubly null mice led to inducible male sterility.

66 plants overexpressing PAE1 exhibited severe male sterility.

67 irst cycles of spermatogenesis, resulting in male sterility.

68 )) and observed disrupted spermiogenesis and male sterility.

69 susceptible to perturbations that result in male sterility.

70 NbSACPD-C expression caused female, but not male, sterility.

71 effect: the M. guttatus allele at the hybrid male sterility 1 (hms1) locus acts dominantly in combina

72 stream of the transcriptional activator MS1 (MALE STERILITY 1), which contains a PHD domain associate

73 h recessive M. nasutus alleles at the hybrid male sterility 2 (hms2) locus to cause nearly complete h

74 MALE STERILITY 5 (MS5) in Brassica napus is a fertility-

75 gical processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian in

76 c) that depends strongly on the dominance of male sterility alleles, while N(en) remains equal to the

77 pecies carries any autosomal dominant hybrid male sterility alleles: reciprocal F(1) hybrid males are

78 Here I show that recessive male-sterility alleles at individual loci are common in

79 Male-sterility alleles contribute to 31% of the inbreedi

80 e restorer loci with complementary recessive male-sterility alleles, as well as a locus with duplicat

81 osely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y h

82 Loss of Six5 results in male sterility and a progressive decrease in testicular

83 ceptor alpha (RARalpha) function resulted in male sterility and aberrant spermatogenesis, which resem

84 results in a novel syndrome characterized by male sterility and brachydactyly.

85 n two of the helicase motifs, causes partial male sterility and complete female sterility.

86 can be used to engineer plant traits such as male sterility and disease resistance.

87 a strong association between X-linked hybrid male sterility and disruption of MSCI and suggest that t

88 cin operon in transgenic male flies induces male sterility and embryonic defects typical of CI.

89 hibited JA-insensitive phenotypes, including male sterility and enhanced resistance to P. syringae in

90 t prevent gene exchange, particularly hybrid male sterility and female species preferences.

91 The recessive male sterility and histoincompatibility (mshi) mutation

92 sgene selection was used to bypass F1 hybrid male sterility and introgress the sex distorter I-PpoI i

93 ster and to show that the insertion leads to male sterility and male mating behavior defects that inc

94 er, we discover at least six genes of hybrid male sterility and none for female sterility by deficien

95 tic basis of association between cytonuclear male sterility and other floral traits in Mimulus hybrid

96 f the genetic architecture underlying hybrid male sterility and segregation distortion between the Bo

97 to be necessary but not sufficient for both male sterility and segregation distortion in F(1) hybrid

98 w that the same gene, Overdrive, causes both male sterility and segregation distortion in F1 hybrids

99 al a complex genetic architecture for hybrid male sterility and suggest a prominent role for reproduc

100 pleiotropic phenotypes, including dwarfism, male sterility and the development of swellings at branc

101 ex determining genes are involved, including male-sterility and female-sterility factors.

102 KEY MESSAGE: We have developed a unique male-sterility and fertility-restoration system in rice

103 with diseases such as cystic kidney disease, male sterility, and hydrocephalus in humans and model ve

104 Coarse fur, male sterility, and low body weight were other abnormali

105 ifferent from most described cases of hybrid male sterility, and may represent an earlier stage of hy

106 ice, which display behavioral abnormalities, male sterility, and perturbed breast development during

107 dation, neurodegeneration, muscular atrophy, male sterility, and reduced life span.

108 ve thus far focused on maternal inheritance, male sterility, and seed sterility.

109 the molecular and functional basis of hybrid male sterility, and strongly reinforce the role of DNA-b

110 ficant reductions in DAZL protein levels and male sterility, and the knockdown was stable over multip

111 s that include facial dysmorphism, dwarfing, male sterility, anemia, and cystic choroid plexus.

112 ects including facial dysmorphism, dwarfing, male sterility, anemia, and progressive polycystic kidne

113 fects in mitochondrial function resulting in male sterility, apoptotic muscle degeneration, and minor

114 Therefore, although F1 male sterility appears to be caused mainly by X-autosome

115 This reduction of 95F myosin causes male sterility as a result of defects in spermatid indiv

116 enetic screens for modifiers of dfxr-induced male sterility, as a means to efficiently dissect FMRP-m

117 ow that knockdown of Gld2 transcripts causes male sterility, as GLD2-deficient males do not produce m

118 later generation (backcross and F(2)) hybrid male sterility between D. virilis and D. americana is no

119 hromosome has only a modest effect on hybrid male sterility between D. virilis and D. americana.

120 tion distortion is similar to that of hybrid male sterility between the same subspecies.

121 Here, I examine the genetic basis of hybrid male sterility between two species of Drosophila, Drosop

122 monocot rice (Oryza sativa) causes complete male sterility, but not in the dicot model Arabidopsis (

123 ines segregating for the restorer region and male sterility, but with unique flanking introgressions.

124 eriments revealed that the slcer6 mutant has male sterility caused by (1) hampered pollen dispersal a

125 It provides the first in vivo model for male sterility caused by a discrete signalling pathway d

126 exhibit the meiotic arrest, DNA damage, and male sterility characteristic of mice lacking piRNAs.

127 d perception mutants is profound sporophytic male sterility characterized by failure of stamen filame

128 plex sex determination involving cytoplasmic male sterility (CMS) alleles interacting with nuclear re

129 e CMS-92 mitochondria that cause cytoplasmic male sterility (CMS) by homeotic transformation of the s

130 al to asexual continuum, whether cytoplasmic male sterility (CMS) facilitates the evolution of patern

131 tima, sex determination involves cytoplasmic male sterility (CMS) genes and nuclear restorers of male

132 olus spp and the degree to which cytoplasmic male sterility (cms) has been characterized in the commo

133 The plant trait cytoplasmic male sterility (CMS) is determined by the mitochondrial

134 hondrial-encoded genes can cause cytoplasmic male sterility (CMS), resulting in the coexistence of fe

135 These results suggest that the cytoplasmic male sterility (CMS)-PPR interaction is highly conserved

136 ochondrial genes associated with cytoplasmic male sterility (CMS).

137 llen abortion, which is known as cytoplasmic male sterility (CMS).

138 Type C cytoplasmic male sterility (CMS-C) is the most commonly used form of

139 ertility (Rf) alleles for S-type cytoplasmic male sterility (CMS-S) are prevalent in Mexican races of

140 S-type cytoplasmic male sterility (CMS-S) in maize is associated with high

141 In the S-cytoplasmic male sterility (CMS-S) system of maize, expression of mi

142 undulata cytoplasm that confers cytoplasmic male sterility (CMS92) or (ii) normal, with the fertile

143 In addition to embryo death and male sterility, conditional psp1 mutants displayed a sho

144 viability, with surviving adults displaying male sterility, decreased female fertility, wing pattern

145 triple knockout mutants suffer from a strong male sterility defect as a consequence of pollen tubes t

146 Male sterility, defined as the absence of viable pollen,

147 nt and cell-wall properties, and resulted in male sterility due to complete disruption of formation o

148 In addition, the mutant showed severe male sterility due to defects in anther and pollen devel

149 defects, while Loxl2 overexpression triggers male sterility due to epididymal dysfunction caused by e

150 utations in the sneaky (snky) gene result in male sterility due to failure in PMBD.

151 ting and that TTC29 mutations are a cause of male sterility due to MMAF.

152 eletion of the SSTK gene in mice resulted in male sterility due to profound impairment in motility an

153 asymmetric genetic basis to X-linked hybrid male sterility during the early stages of speciation in

154 e control of the expression of a cytoplasmic male sterility-encoding gene.

155 pecific genetic divergence underlying hybrid male sterility, especially in contrast with the low degr

156 ity can be highly polygenic and complex, and male sterility evolves substantially faster than female

157 luence mitochondrial genome organization and male sterility expression.

158 etermination region and included a candidate male sterility factor and additional genes with sex-spec

159 Because male sterility factors in hybrids between these species

160 a confirm that the X is a hotspot for hybrid male sterility factors, providing a proximate explanatio

161 d in the general location of the two major t male sterility factors, S1 and S2, within inversions 1 a

162 andard models often find an excess of hybrid male sterility factors, we found no QTL for sterility an

163 inary screen to find additional small-effect male sterility factors, we identified one additional loc

164 genetic basis involving several cytoplasmic male-sterility factors and nuclear restorers.

165 that balancing selection acts on cytoplasmic male-sterility factors in several gynodioecious species

166 cy-dependent selection on linked cytoplasmic male-sterility factors, the putative molecular basis of

167 results clearly suggest that the customized male-sterility & fertility-restoration system can be exp

168 g this gene and its promoter for engineering male sterility for hybrid production of various plant sp

169 We show that the hybrid male sterility gene Odysseus-site homeobox (OdsH) encode

170 to strict outcrossing using the ms1b nuclear male sterility gene.

171 Finally, we describe how male sterility generated by this type of two-component s

172 cy-dependent selection on linked cytoplasmic male sterility genes is a potential candidate.

173 taxa and may affect selection on cytoplasmic male sterility genes when they initially arise.

174 ined by an interaction between mitochondrial male-sterility genes (CMS) that arise via recombination

175 iations between marker loci and the inferred male-sterility genes can be maintained only with very lo

176 istence of nuclear restorers and cytoplasmic male-sterility genes in a population where females are v

177 ovide evidence that evolution of cytoplasmic male sterility has been characterized by frequent turnov

178 osphinothricin (5 mg/l), confirming that the male sterility has been successfully engineered in rice.

179 In diverse crop plants, male-sterility has been exploited as a useful approach f

180 hile X-linked loci that contribute to hybrid male sterility have been precisely localized in many ani

181 ry reproductive barrier in house mice-hybrid male sterility-have been restricted to a single subspeci

182 Hybrid male sterility (HMS) is a rapidly evolving mechanism of

183 in regulatory pathways may result in hybrid male sterility (HMS) when dominance and epistatic intera

184 ous reports of the rapid evolution of hybrid male sterility (HMS).

185 le germ cells, but alpha 85E causes dominant male sterility if it makes up more than one-half of the

186 that dominantly interact with piwi2 to cause male sterility, implying that dosage-sensitive regulatio

187 . musculus domesticus Y chromosome to hybrid male sterility in a cross between wild-derived strains i

188 We then induced male sterility in Arabidopsis plants using the antisense

189 that mutation in one Lectin RLK gene led to male sterility in Arabidopsis.

190 specific Y chromosome, Ymal(+), that induces male sterility in combination with rDNA deletions.

191 n, the D. virilis Y chromosome causes hybrid male sterility in combination with recessive D. american

192 cally, we show that the occurrence of hybrid male sterility in crosses between Drosophila mojavensis

193 TL do not contribute significantly to hybrid male sterility in crosses between the sympatric species

194 t site of the Odysseus (Ods) locus of hybrid male sterility in Drosophila contains such a homeobox ge

195 analyzed the Odysseus (OdsH) gene of hybrid male sterility in Drosophila.

196 ides a valuable tool for the manipulation of male sterility in higher plants.

197 important clues about the genetics of hybrid male sterility in house mice, they have been restricted

198 lved in genetic incompatibilities leading to male sterility in hybrids between Drosophila simulans an

199 Previous work has shown that male sterility in hybrids between Mimulus guttatus and M

200 , we demonstrate that nearly complete hybrid male sterility in Mimulus results from a simple genetic

201 nce pollen development and the occurrence of male sterility in natural plant populations.

202 ernative hypotheses for the lack of observed male sterility in natural populations.

203 Targeted disruption of the gene results in male sterility in otherwise normal mice.

204 potential method for generating maintainable male sterility in plants by using existing agrochemicals

205 ociated with naturally occurring cytoplasmic male sterility in plants, a transgenic approach for RNAi

206 nerative syndromes, senescence in fungi, and male sterility in plants.

207 asmic types, one of which appears to produce male sterility in progeny from any hermaphrodite pollen

208 fies that mutation of Fndc3a is the cause of male sterility in sys mice.

209 ant autosomal factors contributing to hybrid male sterility in the allopatric species pair Drosophila

210 of the CMS cytotypes has been sequenced, and male sterility in the cms-S and cms-T cytotypes is linke

211 Cytoplasmic male sterility in the common bean plant is associated wi

212 expression of SEC31A rescued the conditional male sterility in the double mutant.

213 The conditional male sterility in the mutant is a sporophytic trait, and

214 e that the deletion of Pacrg is the cause of male sterility in the qk(v) mutant.

215 ng of the Ms2 gene and show that Ms2 confers male sterility in wheat, barley and Brachypodium.

216 -linked QTL that underlie measures of hybrid male sterility, including testis weight, sperm density,

217 In addition, we show that hybrid male sterility is a complex phenotype; some hybrid males

218 through chemical mutagenesis showed that the male sterility is a distinctive feature of the qk(v) all

219 Cytoplasmic male sterility is a maternally transmitted inability to

220 It has been proposed that t-mediated male sterility is a severe manifestation of TRD caused b

221 Male sterility is a valuable trait for plant breeding an

222 the mitochondrial genes encoding cytoplasmic male sterility is altered in the presence of one or more

223 Male sterility is an important tool for plant breeding a

224 estorer alleles on Linkage Group 7, and that male sterility is associated with reduced corolla size.

225 hat, in a population of hermaphrodites where male sterility is caused by a dominant allele in a nucle

226 reduction in cell size and fewer cells, and male sterility is caused by loss of the pollen coat and

227 ila melanogaster-D. simulans hybrids, hybrid male sterility is caused by the lack of a single-copy ge

228 It is not known, however, whether F1 male sterility is caused by X-Y or X-autosome incompatib

229 Indeed, male sterility is common among aneuploid mice used to st

230 particular interest in plants as cytoplasmic male sterility is controlled by mitochondrial genotypes,

231 In sunflower, PET1-cytoplasmic male sterility is correlated with the presence of a nove

232 l phenotype but a strong influence on hybrid male sterility is discussed in light of Haldane's rule o

233 Male sterility is dominant in both the parental species

234 Known in over 150 species, cytoplasmic male sterility is encoded by aberrant mitochondrial gene

235 In compliance with Haldane's rule, F1 hybrid male sterility is known to occur in all intercrosses amo

236 Mus musculus musculus X chromosome to hybrid male sterility is large.

237 nctional basis of genetic factors for hybrid male sterility is of great interest.

238 process of species divergence and why hybrid male sterility is often the first sign of speciation, we

239 F(1) hybrid male sterility is thought to result from interactions be

240 Male sterility is, in part, regulated by the mitochondri

241 monstrating that the genetic basis of hybrid male sterility largely differs between these closely rel

242 (p.Val16Gly) missense change rescued mutant male sterility less than the wild-type did.

243 However, Cre expression resulted in male sterility, limiting germ line transmission of the k

244 l tremor indicative of neurological defects, male-sterility, low female fertility, but near normal li

245 Male sterility might not be ideal for many pollinators,

246 ene expression data, we identify a candidate male-sterility mutation in the VviINP1 gene and potentia

247 lear restorer genes that reverse cytoplasmic male sterility (nucleocytoplasmic gynodioecy).

248 three of the four QTL associated with hybrid male sterility occur in collinear (uninverted) regions o

249 Male sterility occurs in Texas (T) cytoplasm maize as a

250 on of ACA12 rescues the phenotype of partial male sterility of a null mutant of the plasma membrane i

251 bundance of piRNAs in germline cells and the male sterility of Miwi mutants suggest a role in gametog

252 The synthetic male sterility of the suz1 zwi-3 double mutants suggests

253 nomic CG14620 transgene rescued deafness and male sterility of tilB mutants.

254 in the relative frequencies of mutations to male sterility or in the frequencies of genes with male-

255 While biocontainment might be achieved using male sterility or transgenic mitigation tools, we believ

256 (SCs) leads to severe testicular atrophy and male sterility owing to rapid depletion of both SCs and

257 ing spermatogenesis, resulting in a complete male sterility phenotype.

258 the 95F myosin heavy chain cDNA rescues the male sterility phenotype.

259 linked QTL associated with a range of hybrid male sterility phenotypes, including testis weight, sper

260 Male sterility plays an important role in F1 hybrid seed

261 However, homozygous mutant mice exhibit male sterility, probably because homologous recombinatio

262 rental species, however, the map location of male sterility reflected the maternal donor in one cross

263 Cytoplasmic male sterility/restorer systems have been proven to be a

264 e genes was instead targeted to the tapetum, male sterility resulted.

265 ain (axDHC) gene, Dnahc8, has been linked to male sterility resulting from aberrant sperm motility.

266 f Dnahc8 expression has been associated with male sterility resulting from an early breakdown in sper

267 ize, with its excellent forward genetics and male sterility screens, was used to identify >50 meiotic

268 similar defects as pink1 and parkin mutants: male sterility, shortened lifespan, and reduced climbing

269 tilB, which also causes male sterility, shows structural defects in sperm flagel

270 e mapping of two crosses showed dominance of male sterility similar to the parental species, however,

271 ction in Arabidopsis resulted in conditional male sterility, since pollen coat lipids are responsible

272 ssociated orf107 transcript from cytoplasmic male sterility sorghum.

273 nction has been used to develop a reversible male sterility system applicable to hybrid crop producti

274 results in the first engineered cytoplasmic male-sterility system in plants, offers a new tool for t

275 n the X Chromosome is more likely to produce male sterility than on autosome (so-called large-X theor

276 Targeted disruption of Roc1b causes male sterility that is partially rescued by expression o

277 an nonsense germline variant associated with male sterility that results in loss of NLRP14 function a

278 Production of hybrid wheat seed relies on male sterility, the blocking of pollen production, to pr

279 For engineering nuclear male sterility, the coding region of Brassica napus cyst

280 However, homozygosity for t causes male sterility, thus limiting the spread of t through th

281 extensive recombination, tentatively linking male sterility to orf293, a mitochondrial gene causing h

282 stolonifera L.) and Arabidopsis, conferring male sterility to the transgenic plants.

283 Restoration of one male-sterility type appears to be controlled by a single

284 We demonstrate that multiple cytoplasmic male-sterility types are present in a gynodioecious popu

285 These male-sterility types each have corresponding nuclear all

286 with duplicate action, which cannot produce male sterility unless the plant is also homozygous for t

287 Results are given of genetic studies of male sterility using plants from two natural populations

288 and closely related species, causing hybrid male sterility via misregulation of two different host p

289 The contribution of each gene to hybrid male sterility was assessed by means of germ-line transf

290 In Arabidopsis, male sterility was observed for two cngc18 null mutation

291 The male sterility was, in each case, heritable, associated

292 Male sterility was, in general, unrelated to homozygosit

293 36H), which extended more proximally, caused male sterility when heterozygous with a complete t haplo

294 , which results in virtually complete hybrid male sterility when homozygous in the genetic background

295 hich carries the kl-3 and kl-5 loci, induces male sterility when present in three copies.

296 class of mutants termed CMS (for cytoplasmic male sterility), which is associated with mutations in t

297 pment genes on the X haplotype likely causes male sterility, while the upregulation of a Y allele of

298 Mutation of either Adad resulted in complete male sterility with Adad1 mutants displaying severe tera

299 osome of the hybrid reflects the location of male sterility within the maternal donor species and (3)

300 Targeted disruption of Pkd2 results in male sterility without affecting spermatogenesis.