ライフサイエンスコーパス: maleate

1 oduce high end-group fidelity poly(propylene maleate).

2 er with dimethyl fumarate than with dimethyl maleate.

3 mide/timolol maleate and pilocarpine/timolol maleate.

4 ctive serotonin uptake inhibitor fluvoxamine maleate.

5 eimine, ethylenediamenetetraacetic acid, and maleate.

6 n on the intraocular distribution of timolol maleate.

7 dration half-reactions using citraconate and maleate.

8 beta,gamma-imido)triphosphate (AMP-PNP), and maleate.

9 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate.

10 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate].

11 -dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate].

12 ks 16 and 32, or twice-daily topical timolol maleate 0.5% (n = 198).

13 of subjects received 1 microdrop of timolol maleate 0.5%.

14 of NMDA receptors with dizocilpine hydrogen maleate (1 microm) prevented both OGD- and glutamate-med

15 tudied fatty Zucker rats given rosiglitazone maleate (50 micromol/kg diet; n = 8) for 9-12 weeks (tre

16 e dicarboxylate linkers, these compounds are maleate (7), allene-1,3-dicarboxylate (10), cis,cis-muco

17 With scrupulously pure dimethyl maleate a 2.8:1 endo:exo mixture of maleate DA adducts i

18 ydro-5H-dibenzo[a,d]cyclophenptan-5,10-imine maleate), a noncompetitive NMDAR antagonist, confirmed t

19 ture of fumarase C with beta-(trimethylsilyl)maleate, a cis substrate for fumarase, has led to the di

20 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate] abrogated this effect.

21 ts, the synthesized monomer, terpene-diallyl maleate adduct, was prepared by D-A addition, hydrolysis

22 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate affected both morphine tolerance and neuronal ap

23 combination dispersible tablet of arterolane maleate (AM) 37.5 mg and piperaquine phosphate (PQP) 187

24 A fixed-dose combination of arterolane maleate (AM), a new synthetic trioxolane, with piperaqui

25 As indexed by MK801 (dizocilpine hydrogen maleate), an open channel blocker, this potentiation was

26 ety of a combination of 150 mg of arterolane maleate and 750 mg of piperaquine phosphate (AM-PQP) in

27 samples were prepared from chlorpheniramine maleate and microcrystalline cellulose (Avicel) of diffe

28 products, consisting of dorzolamide/timolol maleate and pilocarpine/timolol maleate.

29 agonist (serotonin, 5-carboxamidotryptamine maleate, and RO-600175) dose responses were characterize

30 applied coupling partners (e.g., maleimide, maleate, and styrene) to materialize the protocol functi

31 oidal anti-inflammatory drugs, rosiglitazone maleate, and the p53 rescue drug CP-31398.

32 -dibenzo[a,d]cyclohepten-5-10-imine hydrogen maleate] and stationary fluctuation analysis of AMPA rec

33 ntramolecular hydrogen bond in the gas-phase maleate anion are in a range of 14-28 kcal/mol depending

34 se (the barrier for the hydrogen transfer in maleate anion is only 0.2 kcal/mol at the QCISD(T)/6-311

35 n (by 1.5-2 times) in the complexed hydrogen maleate anion relative to that in the naked anion.

36 e intramolecular hydrogen bond in Z-hydrogen maleate anion with respect to the normal hydrogen bond i

37 With dimethyl maleate as the starting material, facile stereoselective

38 aceutical ingredient (API), chlorpheniramine maleate, at the 2% m/m (4 mg) level.

39 Rosiglitazone maleate (Avandia, SmithKline Beecham, Philadelphia, Penn

40 ihydro-SH-dibenzo[a,d]cyclohepten-5,10-imine maleate] before memory reactivation subsequently reduced

41 cids (adipate, malonate, methylmalonate, and maleate), biogenic amines, nucleotide derivatives, pheno

42 -dibenzo[a,d]cylohepten-5, 10-imine hydrogen maleate blocked the additional elevation in taurine asso

43 istinct from interaction of macrophages with maleated bovine serum albumin, collagen, laminin, and fi

44 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate), but neither DA receptor antagonists [SCH-23390

45 M(-1) were determined for both phthalate and maleate carboxylates to the bis-(acetylguanidinium)ferro

46 (2-cyanophenyl)piperazinyl-3-methylbenzamide maleate caused a reversible decrease in postsynaptic GAB

47 The dicarboxylic acid maleate (cis-butenedioic acid) was not an inhibitor of o

48 tereospecificity in the reaction with methyl maleate comes from a less hindered coordination around t

49 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate compared with wild-type controls.

50 gy differences between the E- and Z-hydrogen maleates complexed to Me4N+, Et4N+, and Bu4N+ cation are

51 tment of 14 with HOAc in commerical dimethyl maleate (contains 5% dimethyl fumarate) leads to a nearl

52 hydronaphthalene hydrobromide, or PD 168,077 maleate (D(2)-like, D(2), D(3), and D(4) receptor agonis

53 dimethyl maleate a 2.8:1 endo:exo mixture of maleate DA adducts is still obtained.

54 Perhexiline maleate decreases SREBP2 expression levels and reverses

55 he actions of 2 other GSH depleters, diethyl maleate (DEM) and buthionine sulphoximine (BSO), only 1

56 LY-ar cells treated with diethyl maleate (DEM) or diamide, agents that deplete cellular t

57 Cells treated for 1 h with 1 mM diethyl maleate (DEM) showed a 34 and 53% decrease in GSH and DN

58 xemia, mice were treated with either diethyl maleate (DEM), a glutathione-depleting agent, or buthion

59 were modified by treating cells with diethyl maleate (DEM), D,L-buthionine sulfoximine (BSO), or tert

60 -tributyl phosphorotrithioate (DEF), diethyl maleate (DEM), piperonyl butoxide (PBO) and cyclosporin

61 epletion by 1 hour pretreatment with diethyl maleate (DEM), which conjugates GSH by the GSH-S-transfe

62 ine sulphoximine (BSO; 7.2 mmol/kg), diethyl maleate (DEM; 4.2 mmol/kg), paracetamol (APAP; 3.5 and 1

63 Arg25 in the double mutant, was protected by maleate demonstrating the presence of an additional site

64 This study reports the invention of a simple maleate-derived blocking group for pyridines that enable

65 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate did not prevent induction of the thalamic LTP, s

66 hydronaphthalene hydrobromide and PD 168,077 maleate did not produce such an effect, indicating the i

67 r, 0.25-fold; 4 hours, 0.45-fold) of timolol maleate drug concentrations in intraocular tissues (aque

68 azobenzene derivatives, with maleimides and maleate esters.

69 Quantitative isomerization of the cis-maleate form of all polymers affords the trans-fumarate

70 One of our synthesized maleates has been unambiguously established by single-cr

71 Methergine (methylergonovine maleate) has been advocated for postdural puncture heada

72 confidence interval, 0.63-1.57); fluvoxamine maleate, hazard ratio = 0.98 (95% confidence interval, 0

73 Specifically, we synthesize copper maleate hydrate nanoflakes via bottom-up self-assembly f

74 More impressively, Li(+)-implanted copper maleate hydrate solid-state electrolytes are demonstrate

75 Thus, the Li(+)-implanted copper maleate hydrate solid-state electrolytes shows remarkabl

76 arly equimolar mixture of fumarate- (15) and maleate-IBF Diels-Alder adducts (16 and 17), indicating

77 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate in juvenile (P35) and young adult (P56) rats.

78 ts: Reactive oxygen species-inducing diethyl maleate increased glutathione levels and (18)F-FASu upta

79 Reactive oxygen species-inducing diethyl maleate increased glutathione levels and (18)F-FASu upta

80 Maleate increased urinary MCP-1 protein and mRNA more th

81 NMDA antagonists [AP5 and MK801 (dizocilpine maleate)] indicating glutamate signaling is involved in

82 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate], indicating that deprivation reduced transmitte

83 ruption of tubular morphology during diethyl maleate-induced oxidative stress in an organotypic three

84 dro-3-methyl-5-phenyl-1H-3-benzazepine-7- OL maleate) inhibited the prolonged increase in MPC phospho

85 the effect of Y-27632 on diminished timolol maleate intraocular penetration in NZW rabbits.

86 Inhibition by IMP and maleate is consistent with a chemical mechanism for SAIC

87 Rosiglitazone maleate is the second approved oral hypoglycemic agent o

88 [( o-methylthio)aryloxy]-substituted dialkyl maleates is reported.

89 The unreactive substrate analogue, maleate, is used to induce closure.

90 with the nonhallucinogenic lisuride hydrogen maleate (LHM) and was absent in receptor null-mutant mic

91 Maleate lowered the rate of reduction of the wild-type e

92 ), succinate (suc(2-)), glutarate (glu(2-)), maleate (male(2-)) and fumarate (fum(2-)) anions were st

93 adacidin, l-malate, succinate, fumarate, and maleate), maleate was by far the best inhibitor, competi

94 ts metformin hydrochloride and rosiglitazone maleate may maintain optimal glycemic control in patient

95 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate (MK-801) and by the antagonists of NR2B receptor

96 to the NMDA receptor antagonist dizocilpine maleate (MK-801) and measuring MK-801-induced disinhibit

97 The NMDA receptor antagonists dizocilpine maleate (MK-801) and phencyclidine also increase cell de

98 hydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine maleate (MK-801) blocked the reinstatement of Pavlovian

99 to the NMDA receptor antagonist dizocilpine maleate (MK-801) during periadolescence [from postnatal

100 ith the NMDA receptor antagonist dizocilpine maleate (MK-801) for 24 h before birth also caused an in

101 in vivo, because intraperitoneal dizocilpine maleate (MK-801) injection in young adult rats resulted

102 ntrathecal NMDA-receptor blocker dizocilpine maleate (MK-801) on the peripheral immune response itsel

103 -dibenzo(a,d)cyclohepten-5,10-imine hydrogen maleate (MK-801) prevented cell death, although the non-

104 ihydro-SH-dibenzo[a,d]cyclohepten-5,10-imine maleate (MK-801) to investigate the effects of enhancing

105 periments examined the effect of dizocilpine maleate (MK-801), a noncompetitive N-methyl-Daspartate (

106 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate (MK-801), a noncompetitive NMDA receptor antagon

107 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate (MK-801), a well characterized use-dependent blo

108 sulfamoylbenzo(f)quinoxaline and dizocilpine maleate (MK-801), also suppressed calcium oscillations,

109 udy compared amnestic effects of dizocilpine maleate (MK-801), an NMDA receptor antagonist, and nitro

110 titive NMDA receptor antagonist, dizocilpine maleate (MK-801), on spatial working memory during devel

111 hydro-5H-dibenzo[a,d]-cyclohepten-5,10imin e maleate (MK-801), tritiated kainate, and tritiated amino

112 hydro-5H-dibenzo[a,d]-cyclohepten-5,10imin e-maleate (MK-801), tritiated kainate, and tritiated amino

113 -dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate (MK-801).

114 hydro-5H-dibenzo [a,d]cyclohepten-5,10-imine maleate (MK-801)] or non-NMDA [CNQX or 4-(8-methyl-9H-1,

115 Blockade of NMDARs with dizocilpine hydrogen maleate (MK-801, 20 microM) had a negligible effect on r

116 -dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate (MK-801; hydrogen maleate) on 24-h ischemia-indu

117 g the non-competitive antagonist dizocilpine maleate (MK801) arrested the developmental decrease in e

118 Postnatal injection of dizocilpine maleate (MK801), a specific NMDA antagonist, has been sh

119 MDA receptor antagonist dizocilpine hydrogen maleate (MK801).

120 The maleate moiety in 7-oxabicyclo[2.2.1]hept-2,5-diene-2,3-

121 thod has been found to prepare allyl terpene maleate monomer by substitution reaction at lower reacti

122 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate]) N-methyl-d-aspartate antagonists partially dec

123 erogeneous mouse models of ARF were studied: Maleate nephrotoxicity, unilateral ureteral obstruction,

124 Neither oxidants (sulforaphane and diethyl maleate) nor reducing compounds (N-acetyl-l-cysteine and

125 iously reported net polarization in dimethyl maleate obtained in a homogeneous hydrogenation reaction

126 ,10-imine hydrogen maleate (MK-801; hydrogen maleate) on 24-h ischemia-induced CRH concentrations in

127 etic inhibitory pharmacologic agent, timolol maleate, on the magnitude of nearwork-induced transient

128 aprost ophthalmic solution 0.002% to timolol maleate ophthalmic solution 0.5% in participants with pr

129 5 mM fumarate alone, or 0.1 mM 5'-AMP + 5 mM maleate or 5 mM succinate.

130 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate or CNQX.

131 These analogues were converted into their maleate or hydrochloride salts 13.

132 e 4 was perfused with l-NAME plus pyrilamine maleate or l-NAME plus cimetidine.

133 sed with either the H1 antagonist pyrilamine maleate or the H2 antagonist cimetidine.

134 ibenzo [a,d] cyclohepten-5,10-imine hydrogen maleate] or the GABA(A) receptor potentiator phenobarbit

135 Rosiglitazone maleate (P < 0.05) and CP-31398 (P < 0.05) significantly

136 nyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate; P-9236) (54) displayed a pharmacological profil

137 oride, fluoxetine hydrochloride, fluvoxamine maleate, paroxetine hydrochloride, and venlafaxine hydro

138 inone and commercially available fumarate or maleate precursors is reported.

139 and urine samples from mice with intrarenal (maleate), prerenal (endotoxemia), or postrenal (ureteral

140 raocular penetration of administered timolol maleate presumably due to increased systemic elimination

141 ihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate] provided no protection at any age.

142 tronidazole, phenobarbital, chlorpheniramine maleate, pyridoxine and riboflavin.

143 nternal H-bonding energies for a series of Z-maleate/R4N+ salts (R = CH3, C2H5, CH3CH2CH2CH2) range f

144 h L-buthionine-(S,R) sulfoximine and diethyl maleate, revealed no changes in the cells' ability to tr

145 f adenosine A2a agonist 1 in the form of its maleate salt 2 was achieved.

146 y assigned to treatment with topical timolol maleate solution, 0.5%, or placebo twice daily for 24 we

147 vivo porcine corneal penetration of timolol maleate, sotalol hydrochloride, or brinzolamide incubate

148 ydro-5H-dibenzo [a,d]-cyclohepten-5,10-imine maleate], the curtailed WT and KO responses were indisti

149 e of the present work was to implant timolol maleate (TM) loaded ethyl cellulose nanoparticle-laden r

150 All subjects received timolol maleate to block the sympathetic nervous system and beta

151 Treating mice with diethyl maleate to deplete tissue thiols significantly impaired

152 lyzed the hydration of the minimal substrate maleate to form d-malate.

153 ydro-5H-dibenzo [a,d] cyclohepten-5,10-imine maleate (/) trapping, whole-cell responses to NMDA were

154 pH buffers without an aminosulfonate moiety (maleate, Tris, and bicarbonate).

155 hyperpolarized long-lived state in dimethyl maleate using thiol conjugate addition.

156 However, maleate was an excellent inducer of DctA expression.

157 l-malate, succinate, fumarate, and maleate), maleate was by far the best inhibitor, competitive with

158 hydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine maleate was included in the patch pipette.

159 ocyte function, and GSH depletion by diethyl maleate was shown previously to inhibit expression of NF

160 Ca2+ buffers (5 to 20 mmol/L ADA, citrate or maleate) were introduced into the SR by exposing the cel

161 r 6,000 compounds and identified perhexiline maleate, which can inhibit the growth and induce cell de

162 rovision of either exogenous H2O2 or diethyl maleate, which raises intracellular H2O2 levels.

163 event-based oral PrEP (tenofovir disoproxil maleate with emtricitabine), as appropriate.

164 addition reaction of achiral dipolarophiles (maleates) with chiral, open-chain sugar-derived azomethi

165 lular uptake after OS induction with diethyl maleate, with and without anti-xCT small interfering RNA

166 lly fluoxetine hydrochloride and fluvoxamine maleate-with decreased mortality among patients with COV