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1 Furthermore, parainflammatory neutrophils manifest as 2 distinct subpopulations-based on size, gra
4 e basis that corrosion and defects are often manifest as a change of thickness in the steel from whic
6 incentive salience to reward cues, which can manifest as a propensity to approach and contact pavlovi
8 GAS), is a human bacterial pathogen that can manifest as a range of diseases from pharyngitis and imp
10 subtypes of HIV-associated vasculopathy may manifest as a result of an immune reconstitution-like sy
11 space, indicating multiple origins, but can manifest as a single feature at the sensor level because
12 vealed upon competition or by system stress, manifest as a strikingly heightened susceptibility to pr
13 olidation, and the proliferative phase would manifest as a tendency toward a more linear morphology.
18 rlying this was a striking molecular synergy manifested as a dramatically altered gene expression pro
19 n atypical higher-order chromatin structure, manifested as a global loss of local topologically assoc
21 -term responses to allopolyploidy are mainly manifested as a high proportion of homoeologous gene pai
22 f cleavage of the bifunctional marker, which manifested as a marked shift in the normalized YFP/mCher
24 cted by self-report; radiographic recurrence manifested as a new stone in 35%, stone growth in 24%, a
25 the pancreas by gut-derived lymphocytes that manifested as a pancreatic insulitis with beta-islet cel
29 f a permanent electric polarization density, manifested as a spontaneously broken symmetry in distinc
30 fect memory of the reactants' nuclear spins, manifested as a strong parity preference for the rotatio
34 ch a unique demonstration of the limited GPA manifesting as a bilateral ocular involvement and comple
35 o a series of sequential sodiation reactions manifesting as a cascade of processes observed in the el
36 gen metabolism and glycosylation, the latter manifesting as a congenital disorder of glycosylation (C
37 athy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour.
39 icity arising from gestational exposures and manifesting as a shortened anogenital distance (AGD) in
42 results demonstrate that UNC-45B impairment manifests as a chaperonopathy with progressive muscle pa
50 nisms by which CPs are regulated in vivo LTH manifests as a persistently reduced behavioral response
52 action potential conduction velocity, which manifests as a progressive increase in response latency.
53 al degeneration associated with CLN2 disease manifests as a progressive, symmetrical decline, which a
54 causes rapid degradation of SLC25A46, which manifests as a rare disease, pontocerebellar hypoplasia.
56 criptional activator and that its disruption manifests as a reduction of RNA polymerase II (Pol II) o
58 In ring laser gyroscopes (RLGs), this shift manifests as a resonance splitting in the emission spect
62 yclic voltammetry (FSCV) studies, biofouling manifests as a shift in the peak oxidative potential of
64 local change in dynamic contact angles which manifests as a smooth and continuous motion of the CL.
67 ge localization on the picosecond time scale manifests as a time-dependent Stark shift in the visible
68 sure' in collecting lymphatic vessels, which manifests as a transient drop in pressure downstream of
72 ormalities and metabolic waste accumulation- manifesting as acute kidney injury (AKI), a common disor
73 ice showed developmental irregularities that manifested as adult-onset glomerulosclerosis and protein
74 ciated gene expression changes predominantly manifested as alterations in the efficiency of mRNA tran
76 EGABA) and increased intrinsic excitability (manifest as altered spike initiation properties) were ne
77 si-rhythmic intraseasonal oscillations (ISO) manifested as alternate 'active' phases of copious rainf
78 ease, cells experience various stresses that manifest as an accumulation of misfolded proteins and ev
80 e damage accumulation, which leads to aging, manifest as an increasing probability of system collapse
81 O(3) and the magnetic topological insulator, manifested as an exchange bias when the sample is field-
83 jections caused systemic inflammation, which manifested as an increase in plasma pro-inflammatory cyt
84 mplication of such actin destabilization was manifested as an increase in specific agonist binding an
87 cate multi-electron-conversion reactions and manifests as an effective and efficient strategy to enha
92 genetic risk for schizophrenia appears to be manifest as anxiety and negative symptoms during adolesc
93 .5 cells infected with the JFH-1 HCV strain, manifesting as apoptosis highly correlated with growth a
96 , as well as associated immune dysregulation manifesting as autoimmunity or allergic inflammation.
97 iency (CVID) experience immune dysregulation manifesting as autoimmunity, lymphoproliferation, and or
98 differential regulation of CaMKII function, manifested as autoinhibition (pT305 phosphorylation) fol
99 in aspartate depletion that was specifically manifested as auxotrophy within PIK3CA mutant cells.
100 c dysplastic kidney or cystic dysplasia), or manifest as bilateral cystic disease (eg, autosomal rece
101 erial, this flow-induced elastic deformation manifests as bulging near the cell outflow; bulges that
102 he index family, presentation was milder and manifested as cardiac fibrosis and an exquisite sensitiv
103 Age-dependent changes in metabolism can manifest as cellular lipid accumulation, but how this ac
104 is driven by changes in gene expression that manifest as changes in cellular phenotype or function.
106 the observed data, since energy flow may be manifested as changes in both structure and dynamics.
110 ow obstruction is established early in life, manifests as childhood asthma and wheezy bronchitis, and
114 sative agent of amebiasis, an infection that manifests as colitis and, in some cases, liver abscess.
116 cardiotoxicity of oncological drugs that may manifest as contractile and electrophysiological dysfunc
120 ctomized 30-year-old patient with severe WAS manifesting as cutaneous vasculitis, inflammatory arthro
121 We have previously identified anhedonia, manifest as decreased sucrose preference and social play
122 e that, as in humans, normal aging primarily manifests as defects in relaxation (diastole) while pres
124 jects displayed membrane trafficking defects manifested as delayed endoplasmic reticulum (ER)-to-Golg
127 , as does the degree to which incomplete XCI manifests as detectable sex differences in gene expressi
128 ty to TMP/UVA relative to wild-type animals, manifested as developmental arrest, defects in adult tis
129 nge of autoimmune/dermatologic disorders can manifest as DG, although the two more common are oral li
132 ent intraporous 2-butanol solvent structures manifest as differences in the activation and adsorption
133 rate within and between populations largely manifested as differences in genome-wide recombination r
134 lectrons and chiral molecules are physically manifested as differences in the measured photoionizatio
136 involvement is the major cause of death and manifests as dilated cardiomyopathy, heart failure, arrh
137 angle for photon-to-plasmon coupling, which manifests as directly observable dark bands in the refle
141 t distinguishes one person from another, may manifest as diverse rearrangements of functional connect
144 whether reactivity to specific stressors may manifest as drug seeking depends on biological sex.
146 including major depression and schizophrenia manifest as dysfunction of the GABAergic system within t
147 genital-onset disorder of connective tissue, manifesting as early-onset joint hypermobility, joint co
148 netic burden arising from human mutant LRRK2 manifests as early pathophysiological changes to dopamin
150 s provided conclusive evidence that fitness (manifest as emergence of a dominant clone) changed coinc
151 infections, chronic Q fever develops, mostly manifesting as endocarditis, infected aneurysms, or infe
152 risingly, this therapeutic variation did not manifest as enhanced disaggregase activity, but rather a
153 rkably similar activity-dependent modulation manifesting as epochs of enhanced intrinsic excitability
157 Highly penetrant hereditary thyroid cancer manifests as familial nonmedullary thyroid cancer (FNMTC
159 etal testes that appear between e19.5-e21.5, manifesting as focal aggregation of Leydig cells and ect
160 A sequencing, quantitative trait loci (QTLs) manifest as fragment count differences between individua
162 of the p53 pathway and DNA damage response, manifesting as gamma-H2A.X positivity in neurons of the
164 impaired substrate delivery (n = 158, 54.1%) manifesting as global or regional hypoxia or ischemia du
165 ic effects from paclitaxel with trastuzumab, manifesting as grade 3 or 4 LVSD or asymptomatic LVEF de
166 of biofilm communities to regional templates manifested as gradients of carbon, nitrogen, and phospho
167 also observed increased respiratory capacity manifesting as greater minute volume, as well as enhance
169 on of lipid droplets in infected hepatocytes manifests as hepatosteatosis, a common pathology observe
170 nges associated with domestication may first manifest as heritable changes to global patterns of gene
171 shoot stress responses are also common, and manifest as high levels of persistent anthocyanin pigmen
173 es highly dynamic [Ca(2+)]cyt signaling that manifest as hundreds of discrete [Ca(2+)]cyt spikes, whi
174 t increased risk for CVD at 4 months of age, manifesting as hypertension, increased abdominal fat, el
175 lar organ, impaired terminal differentiation manifests as immature stereocilia and kinocilia on the a
178 mories formed during sensorimotor adaptation manifest as improved adaptation when sensorimotor pertur
179 ories formed during sensorimotor adaptation, manifest as improved relearning (e.g., savings), have re
180 icant plasticity in the sensorimotor cortex, manifested as improved discriminability of movement info
181 ommon feature of neuropsychiatric disorders, manifesting as impulsivity for anticipated incentives.
182 ure of posttraumatic stress disorder (PTSD), manifests as inappropriate, uncontrollable expression of
183 n have nontargeted heterologous effects that manifest as increased protection against nonvaccine infe
186 ses to uncoat in endosomes more efficiently, manifesting as increased replication rate in typical con
187 evidence that augmented BK channel activity manifests as increased intrinsic excitability in individ
188 detect or else conflate generalization that manifests as increased learning rate with generalization
189 creased susceptibility at the cellular level manifests as increased susceptibility to typhoid fever i
190 ility in cells expressing mutant POT1, which manifests as increased telomere mitotic DNA synthesis at
192 t of mGluR5 activation is to produce anxiety manifested as indiscriminate fear of both tone and conte
193 llation of neurodevelopmental disorders that manifest as intellectual disability, epilepsy, autism, o
194 nfected cells produce paracrine signals that manifested as intercellular calcium waves (ICWs), observ
195 ubstantial microscale internal stresses that manifest as intergranular and intragranular residual str
196 ins modulate diverse downstream effects that manifest as interindividual differences in efficacy, adv
198 ologically relevant genetic alterations that manifest as intratumor heterogeneity, these aggregate an
199 In histological analyses, these changes manifested as larger lesion size, increased lineage-trac
204 it dysregulated homeostatic expansion, which manifests as lymphoproliferative disease with autoantibo
206 egnancy impose long-term detrimental effects manifesting as metabolic dysfunction in adult male offsp
208 ureus conferred responsiveness to IL-20 that manifested as modification of actin polymerization and i
209 red through environmental factors and may be manifested as molecular "scars." Some of these scars can
210 dimorphism in the mammalian immune system is manifested as more frequent and severe infectious diseas
211 nts with an acute lung injury pattern at CT, manifesting as multifocal ground-glass opacity and/or co
212 DSA elicit cycles of injury and repair that manifest as multilamination of the peritubular capillary
214 omozygous IL2RB mutation in the WSXWS motif, manifesting as multisystem autoimmunity and susceptibili
216 ght how defects in embryonic development may manifest as neurodegenerative pathology in an adult.
218 ately, these inherently stochastic processes manifest as noise in gene expression, where even genetic
219 cells producing disseminated plasma leakage, manifesting as nonspecific fever, headache, and maculopa
225 striking predilection for chronic cystitis, manifesting as persistent bacteriuria, high-titer bladde
227 ve change in membrane phospholipid polarity, manifested as phosphatidylserine externalization, which
229 nt sound associated with very bright meteors manifests as popping, hissing, and faint rustling sounds
232 lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL) and multi
233 in the developing embryonic mouse brain that manifests as pro-inflammatory cerebrospinal fluid (CSF)
234 By E18, these early patterning effects are manifest as profound changes in cell fates [short hair c
235 pression of genes encoding metabolic enzymes manifested as profound systemic metabolic changes that d
236 r infection in IFN-alphabetagammaR(-/-) mice manifested as profoundly elevated aspartate transaminase
237 used by the Human Papilloma Virus (HPV) that manifests as profoundly altered phonatory and upper resp
238 D) after hematopoietic cell transplant (HCT) manifests as progressive airway and parenchymal lung fib
239 ts), long-lasting nociceptor neuroplasticity manifested as prolongation of prostaglandin E(2) (PGE(2)
240 N) is a common complication of shingles that manifests as prolonged excruciating pain, which has prov
241 rdetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hyperte
244 ncidence of recurrent venous thromboembolism manifested as pulmonary embolism or deep vein thrombosis
246 e marked by organ failure that most commonly manifests as pulmonary fibrosis and are associated with
248 oxicity that culminates in neuron injury and manifests as re-experiencing symptoms and other memory a
249 t-virus evolutionary arms races, which often manifest as recurrent amino acid changes (i.e., positive
250 bit perturbed humoral and cellular immunity, manifesting as recurrent infections, autoimmunity, hepat
251 el-dependent activity via real-time fMRI and manifested as reduced amygdala reactivity to visual stim
252 ffer late effects of poorer postural control manifested as reduced contribution of vision and as redu
253 ith mucosal immune system dysfunction, which manifests as renal IgA deposition that leads to impairme
255 s an inherited and irreversible disease that manifests as retinitis pigmentosa (RP) and bilateral neu
258 BMT) and is characterized by tissue fibrosis manifesting as scleroderma and bronchiolitis obliterans.
260 the intensive care unit (ICU) most commonly manifests as sepsis, ventilator-associated pneumonia, an
261 infection in hospitalized older adults often manifested as severe, life-threatening lower respiratory
262 rbon resources to new versus existing roots, manifest as sharply distinct global RSAs over time.
263 istic, but are subject to tradeoffs that may manifest as shifts in host and symbiont metabolism, cell
264 verse group of skeletal dysplasias and often manifest as short stature, growth-plate irregularities,
265 ceptibility to infections that are likely to manifest as side effects of blocking these cytokines (or
267 g of hypermutation confined to the locus and manifesting as SNVs and indels predominantly within gene
269 , the Chern number (a topological invariant) manifests as spatial winding of the phase of the circula
271 eas low-penetrance hereditary thyroid cancer manifests as sporadic disease and is associated with com
272 CC-IM) exhibit spontaneous Ca(2+) transients manifesting as stochastic events from multiple firing si
273 and heterochromatic chromosomal regions, and manifests as striking bimodal patterns of gene expressio
274 ited by public and political opposition that manifests as structural barriers to HIV prevention, such
275 t whether the growth of lung adenocarcinomas manifesting as subsolid nodules at chest CT is accuratel
276 The overall volume growth of adenocarcinomas manifesting as subsolid nodules at chest CT was best rep
277 d Methods Patients with lung adenocarcinomas manifesting as subsolid nodules surgically resected betw
278 uilibrium, we observe an instability that is manifested as substantially enhanced current fluctuation
279 iders' empathy during the pain procedure and manifested as subtle changes in providers' facial expres
281 th a primary immunodeficiency, predominantly manifesting as susceptibility to Epstein-Barr virus (EBV
282 spontaneous and stimulus-evoked activity can manifest as synchronous activation of neuronal assemblie
283 In the spectral domain, nonlinear dynamics manifest as the development of a chain of harmonics stat
285 anism for priming naive B cell responses and manifested as the induction of SA-dependent pan-activati
286 ber congenital amaurosis type 4 (LCA4), that manifests as the loss of vision during the first year of
287 erative disease, adrenoleukodystrophy, which manifests as the spinal cord axonopathy adrenomyeloneuro
288 to the untoward effects of osteoporosis that manifest as thinner, more porous alveolar bone, PDL thin
289 induces structural and chemical changes that manifest as toposelective hydrogenation of alternating r
290 tions caused by depletion of ERalpha largely manifest as "translational offsetting" of the transcript
292 ll individuals with missense variants, often manifesting as treatment-resistant infantile epileptic e
293 strate a reduced efficacy of inhibition that manifests as triggering of seizures at room temperature
295 he oncogenic role of DDX5, at least in part, manifests as up-regulation of respiration supporting the
299 ng-associated ependymal-cell pathologies can manifest as ventricular gliosis, ventricle enlargement,
300 genetic interaction between Tbx5 and Mef2c, manifesting as ventricular septation defects, was valida