ライフサイエンスコーパス: manifold

1 eural population responses called an 'object manifold'.

2 S(N)2-like nucleophilic attack/ring-opening manifold.

3 he crystal field splitting of the (4)I(15/2) manifold.

4 th the evolution of the system's temperature manifold.

5 ties within an organometallic C-C activation manifold.

6 phs through subspace analysis on a Grassmann manifold.

7 a drift-diffusion process over a ring-shaped manifold.

8 o the injection valve of the continuous flow manifold.

9 most of the broadening in the OH stretching manifold.

10 ted molecule from the singlet to the triplet manifold.

11 elation," involving both a string and the 3D manifold.

12 g element in a flow injection analysis (FIA) manifold.

13 and one forbidden, within the S = (3)/2 spin manifold.

14 on via a dual cobalt and photoredox catalyst manifold.

15 effects of plant volatiles on herbivores are manifold.

16 from higher energy states within the (3)MLCT manifold.

17 the ion trap mass analyzer inside the vacuum manifold.

18 ultrafast dimerization occurs in the singlet manifold.

19 ries is more rapid than in the mannopyranose manifold.

20 ed with higher reaction rates in the triplet manifold.

21 that the reaction proceeds through a radical manifold.

22 absent other human pressures, which are now manifold.

23 ns meet again to expand the polyene-carbonyl manifold.

24 is isometric to the latent variables of the manifold.

25 can be individually approximated by a single manifold.

26 y in the low-dimensional population response manifold.

27 ic topological character of the Te p-orbital manifold.

28 , the principle of least action on a Finsler manifold.

29 cs that are constrained to a low-dimensional manifold.

30 odule has been integrated into the presented manifold.

31 yields and high enantioselectivities in both manifolds.

32 the intrinsic dimension of extremely curved manifolds.

33 ransformation routes used and their involved manifolds.

34 facilitating exploration of vastly larger GI manifolds.

35 d formations enabled by Ni- and Cu-catalyzed manifolds.

36 by crystallography and HPLC for both product manifolds.

37 loying this class of catalysts in photoredox manifolds.

38 cribe discrete spaces as homogeneous network manifolds.

39 interactions in both the singlet and triplet manifolds.

40 information in multidimensional steady-state manifolds.

41 tivation modes and unprecedented selectivity manifolds.

42 on topologically-constrained configurational manifolds.

43 z for transitions within the same rotational manifold(1), a few gigahertz for hyperfine transitions,

44 400 nm excites the molecule into the quintet manifold ((5)MLCT <-- (5)MC) and leads to the observatio

45 Based on the puromycin (6) structural manifold, a series of 10 novel derivatives of 6 was prep

46 We show that trends serve as the control manifolds about which ST and SL fluctuate.

47 esulting in a single 2D image of the stained manifold across which contrast is optimized and illumina

48 or future therapeutic interventions, but the manifold actions of extracellular DNA traps complicate t

49 its biological context, as the expression of manifold adaptations, compels a rethinking of measuring

50 ryptophan was detected with a flow-injection manifold after reacting with mM order of fluorogenic o-p

51 MATCHER uses manifold alignment to infer single cell multi-omic profi

52 harmaceuticals and health care products grew manifold, allowing an increase in life expectancy and a

53 n of an equifinality method (Goal Equivalent Manifold; an index related to the set of effective motor

54 We used Uncontrolled Manifold analysis to quantify the variability in the tas

55 gative matrix factorization and uncontrolled manifold analysis were performed to decompose inter-repe

56 MF) with HPLC-MS, using a custom, 3D-printed manifold and a custom plugin to the popular open-source

57 ping was enabled by a low-dimensional curved manifold and allowed us to further probe the potential c

58 Cartridges with and without a sheath gas manifold and an electrostatic lens are compared with res

59 d synaptic caching, boosts energy efficiency manifold and can be used with any plasticity rule, inclu

60 simple properties of the tangent space of a manifold and extends the usual correlation integral esti

61 e causes of this complex human condition are manifold and include a substantial genetic component.

62 oes not depend on the shape of the intrinsic manifold and is highly accurate, even for exceedingly sm

63 We show how this manifold and plate design can be used to expose cells to

64 se studies directly probe the excitonic spin manifold and reveal the fine spin-splitting at the condu

65 ary mechanistic study supports this reaction manifold and shows the intersection of metal-catalyzed H

66 performance reconfigures the low-dimensional manifold and that deviations from these patterns relate

67 ossing (ISC) from the triplet to the singlet manifold, and hydrogen migrations.

68 ciated with changes in the geometry of those manifolds, and recent theoretical progress connects this

69 The manifold applications for cyclized analogues of the arom

70 a new class of fluorescent nanocrystals for manifold applications, from biophotonics to nanomedicine

71 fication of samples on a molecular level has manifold applications, from patient classification regar

72 ternal noise limits memory fidelity, and the manifold approach reveals new dynamical trajectories dur

73 nsionality reduction methods such as Uniform Manifold Approximation and Projection (UMAP) can be very

74 In this work, uniform manifold approximation and projection (UMAP) is applied

75 Here, we use the Uniform Manifold Approximation and Projection (UMAP) method on p

76 and projected onto a 2D space using Uniform Manifold Approximation and Projection (UMAP), a novel no

77 c neighborhood embedding (t-SNE) and uniform manifold approximation and projection (UMAP).

78 Like LargeVis and Uniform Manifold Approximation and Projection, the model produce

79 d stochastic neighbor embedding, and uniform manifold approximation and projection.

80 NMR spectra of each member of the structural manifold are predicted and compared with the experimenta

81 t stable latent cortical dynamics within the manifold are the fundamental building blocks underlying

82 These neural manifolds are spanned by specific patterns of correlated

83 se naturally arise within a single p-orbital manifold as a general consequence of a trigonal crystal

84 ent along the constant speed goal equivalent manifold as postulated by Dingwell et al. 10.1371/journa

85 a known for synthetic libraries, and all had manifold ascribed bioactivities, designating them as inv

86 vironment that controls their properties via manifold avenues including weak protein-macromolecule in

87 Using a manifold-based analysis of experimental diffraction snap

88 This manifold-based view of motor cortex may lead to a better

89 ation step and the radical chain propagation manifold, both mediated by the chiral enamines.

90 We use the Manifold Boundary Approximation Method (MBAM) as a tool

91 opelled rods confined to a compact spherical manifold by means of Brownian dynamics simulations.

92 lights opportunities to access new catalytic manifolds by merging photoredox catalysis with biocataly

93 iginating from either the singlet or quintet manifold can be explored using variable wavelength laser

94 ected during real-time evolution can lead to manifold changes in enzyme function and bacterial fitnes

95 This reaction manifold circumvents limitations in present-day technolo

96 Histamine intolerance is thought to trigger manifold clinical symptoms after ingesting histamine-ric

97 nhancing the photo-thermoelectric voltage by manifold compared to previous reports.

98 ge with an electrostatic lens and sheath gas manifold compared to the cartridge without (15% and over

99 The manifold comprised a 1.0 cm length monolithic column coa

100 glass transition is a low-dimensional, slow manifold consisting largely of the Euler angles describi

101 The light-controlled reaction manifold consists of a so-called o-quinodimethane specie

102 n-carbon bond formation can be gauged by the manifold constraints that were efficiently overcome, nam

103 high-dimensional landscapes of cell states (manifolds) constructed from transcriptional phenotypes.

104 t shared variance increases, consolidating a manifold containing consistent neural trajectories that

105 ic population of the [Cu(2)(mu(2)-NAr)] pai* manifold, contrasting previous methods for engendering i

106 d by multiple environmental cues pointing on manifold control of targeted protein degradation.

107 manifolds' radius, dimensionality and inter-manifold correlations.

108 random geometric graphs in three Lorentzian manifolds corresponding to universes filled only with da

109 Here we define Complex Quantum Network Manifolds (CQNM) describing the evolution of quantum net

110 he ability to generate novel molecules along manifolds, defined by chemical property analogues, posit

111 on of lattice tight-binding models on closed manifolds demonstrates that these results continue to ho

112 We fabricated a manifold designed to use flow-encoding to produce sequen

113 s orthogonal to conventional metal-catalysed manifolds, diverse aryl and heteroaryl partners can be r

114 rease due to climate change, which will have manifold ecological and societal impacts including the p

115 ture preserving visualization with nonlinear manifold embedding of normalized spectral data.

116 opulation variation in vaccine responses are manifold, emerging evidence points to a key role for the

117 Exploration of this manifold enabled ordering of regulatory pathways, princi

118 ance of the continuous structure of the data manifold enables the better visualisation of this examin

119 ghts how individual gut bacteria orchestrate manifold enzymes to metabolize the most challenging glyc

120 Our generation method renders manifold experiments possible to investigate triangulene

121 This molecular switching manifold exploits intramolecular coupling of multiple re

122 o ketene occurs by tunneling, on the triplet manifold, followed by intersystem crossing.

123 e demonstrate the broad implications of this manifold for accomplishing numerous C(sp(3))-H bond func

124 litates the more accurate utilisation of the manifold for detecting the adulterants.

125 tion of an embedded electrostatic lens and a manifold for internal sheath gas distribution and delive

126 and our approach represents a new catalytic manifold for metal-free C-C bond formation.

127 tion of multiple transitions within a single manifold for QC remains unrealized in these high-spin sp

128 learning can explain the cognitive positive manifold for social animals, including humans.

129 of the transformation reveals an unexpected manifold for stereoinduction involving dynamic kinetic r

130 we disclose a general and reliable reaction manifold for the construction of highly substituted hete

131 One manifold for the functionalization of aromatic molecules

132 much research on the use of these activation manifolds for (18)F-fluorination.

133 as dynamics over relatively low-dimensional manifolds formed by correlated patterns of neurons.

134 , the search space is treated as the product manifold [Formula: see text], where [Formula: see text]

135 racter arises from a shrinking TTFtt(2-) pai-manifold from the Fe(II)-centered spin-crossover.

136 ely estimate the geometry of low-dimensional manifolds from a small number of linear projections of t

137 heoretical and computational Goal Equivalent Manifold (GEM) framework to generate predictive models,

138 ucture of variability near a goal equivalent manifold (GEM).

139 We test the method on manifolds generated from global transformations of high-

140 t and given the importance of the data-space manifold geometry for machine-learning model selection,

141 The new catalytic manifold has been showcased in the synthesis of the bioa

142 s and how the geometry and dynamics of these manifolds help reduce timing variability.

143 ontrol and the framework of the uncontrolled manifold hypothesis to explore the synergic control of a

144 malies in data which may fail to satisfy the manifold hypothesis.

145 ntages of such a copolymerization system are manifold: (i) no need for multistep catalyst/ligand synt

146 ought, heat stress, and insect attacks, with manifold impacts on forest ecosystems.

147 Population of this orbital manifold in accordance with Hund's rules could potential

148 -dimensional, secondary-structure constraint manifold in conformation space, where motions are largel

149 lows: (i) extracting and mapping the stained manifold in each stack into a single 2D projection plane

150 Accessing the triplet manifold in pai-conjugated systems would also include a

151 importance of the newly formed excited-state manifold in TBPCExBox(4+) for the population of the low-

152 developed algorithm that actually finds the manifold in the stack based on maximizing contrast, inte

153 samples are projected onto a low-dimensional manifold in the subspace spanned by those genes.

154 mputations to interpolate over task-relevant manifolds in a high-dimensional parameter space.

155 al place cells span distinct low-dimensional manifolds in different environments.

156 sults from establishing task-relevant neural manifolds in sensorimotor cortical areas and how the geo

157 general method for embedding a 'manifold of manifolds', in which each datapoint in the higher-level

158 yzed C(sp(3))-H activation via various redox manifolds, including Pd(0)/Pd(II), Pd(II)/Pd(IV), and Pd

159 -system crossing between triplet and singlet manifolds, indicating that optically-addressable spin de

160 essels, act as molecular fossils and provide manifold information about past people's subsistence, di

161 In addition, endophytic microbiota and the manifold interactions between members, including pathoge

162 Our new reaction manifold is also showcased in the total synthesis of two

163 The chemical selectivity of the manifold is controlled by the amount of ene present in t

164 The effectiveness of the reaction manifold is evidenced by following the transformations o

165 The reported light-controlled reaction manifold is highly attractive because a simple external

166 inues to reduce until an acceptable solution manifold is reached.

167 Due to the lower symmetry, the t 2g manifold is split and the quasiparticle weight is renorm

168 statistical approach to estimate a nonlinear manifold is well suited for raw, unfiltered gene counts

169 s and provides molecular level insights into manifold issues of chemical and biochemical relevance.

170 By analyzing wild-type yeast and a manifold knockout strain lacking all putative lactic aci

171 ested density of states in the excited-state manifold leads to rapid deactivation.

172 Recently, manifold learning (ML) has been used to perform CBIR in

173 We used a manifold learning algorithm called "the Sequencer" to si

174 perspective on topological data analysis and manifold learning approaches to the analysis of large-sc

175 or these unobserved molecular changes with a manifold learning method applied to RNA-Seq data collect

176 Here we propose the use of diffusion maps, a manifold learning technique, to obtain an embedding of p

177 onally links the MD simulator with nonlinear manifold learning techniques.

178 Here we use manifold learning to map the space of metabolic networks

179 mework that combines archetypal analysis and manifold learning to provide a ready-to-use analytical a

180 included principal component analysis (PCA), manifold learning, and unsupervised clustering to identi

181 The mild photosensitized manifold leverages the intermolecular formation of oxazo

182 that the alignment of low-dimensional neural manifolds (low-dimensional spaces that describe specific

183 thod are invariant to diffeomorphisms of the manifold, making it possible to match between different

184 s suggest that the DKR-based stereoinduction manifold may be responsible for stereoselectivity observ

185 Since these manifolds may have different intrinsic dimensions, local

186 ectures form due to self-organization of the manifold mineral and organic soil components to distinct

187 oach that may be applied clinically to treat manifold neurodegenerative diseases characterized by axo

188 cepts of enzymatic catalysis to a reactivity manifold not represented in biology.

189 ttractive EPR spectroscopic properties for a manifold of applications.

190 Vision operates directly on the manifold of cell-cell similarity and employs a flexible

191 eneous catalysis led to the development of a manifold of chiral NHCs as stereodirecting ancillary lig

192 a twisted chromophore geometry, producing a manifold of close-lying excited states and dipole moment

193 of lipid bilayers are recent examples of the manifold of complex devices that can be achieved.

194 The evidence is a positive manifold of correlated assumptions and variables.

195 The spatial size and electronic energy of a manifold of CT states are resolved at the zinc phthalocy

196 ' is a property which can be attributed to a manifold of different immaterial systems, such as ideas,

197 Despite a manifold of different umpolung methods available today,

198 The system relaxes to the lowest manifold of divalent cobalt ((4) T 1) in 150-200 fs.

199 bias dependence and reveals the higher-lying manifold of DOS sites responsible for CT-EL.

200 ow for a detailed characterization of the 3d-manifold of effectively localized Co(IV) centers and pro

201 he crystal field splitting of the (4)I(13/2) manifold of Er implanted Si, and allows us to revise the

202 me softening and reconstruction of an entire manifold of low-energy acoustic and optic branches acros

203 ation (200 +/- 15 fs) within the superatom D manifold of lowest-unoccupied molecular orbitals was res

204 PhEMD is a general method for embedding a 'manifold of manifolds', in which each datapoint in the h

205 ication technique is thus established with a manifold of opportunities in photonic applications.

206 viding easy access to the full computational manifold of our system and making it convenient to imple

207 n for the apo-monomeric CBD occurs through a manifold of pathways that are more divergent than previo

208 he doubly excited, spin-singlet state to the manifold of quintet states and comment on the mechanism

209 data are concentrated near a single unknown manifold of relatively small intrinsic dimension.

210 ng to our analysis, metal coordination has a manifold of rewards, putting it primo loco in opportunit

211 The pai-manifold of the central BC(5) ring coordinates to chromi

212 shell-closing gap at the top of the occupied manifold of the delocalized electronic superatom spectru

213 lap-determines the splitting within the spin manifold of TT states.

214 ansition-metal-carbon bonds is a mechanistic manifold of vast significance: it underlies the Fischer-

215 s reveal spectral features associated with a manifold of vibrational Feshbach resonances and bound st

216 The resulting manifold of vibronic states drives sub-100 fs fission wi

217 rve as useful samplers from the ground-state manifolds of combinatorial optimization problems.

218 in sub-millisecond timescales, show complex manifolds of conformational states, and often show state

219 exclusively by relaxation through electronic manifolds of different spin multiplicity: trans-to-cis i

220 i) quantum annealers sample the ground-state manifolds of spin glasses very differently than thermal

221 rsion not of bulk states, but rather between manifolds of surface states.

222 The manifolds of the contempt network, differentially engage

223 which we believe originates from the energy manifolds of the modulated Mn(2+) sublattice and its def

224 in which each datapoint in the higher-level manifold (of biospecimens) represents a collection of po

225 collection of points that span a lower-level manifold (of cells).

226 via electronic relaxation within the singlet manifold on a time scale of 40 ps; in contrast, cis-to-t

227 id ISC processes into and out of the triplet manifold on time scales of approximately 2 ps and 0.4 ns

228 les and vice versa are a few examples of the manifold opportunities associated with the use of semico

229 tion of a specific state in the valence band manifold originating from the hybridized lone pair in ni

230 new catalytic and/or multicomponent reaction manifolds out of classical reactivity patterns.

231 This manifold perspective enables blind discovery and decodin

232 change interaction in the correlated triplet manifold plays a critical role dictating (1)TT yield in

233 with bioorganisms; as a result, FGNs present manifold possibilities for diverse biological applicatio

234 ion metric, which we call denoised embedding manifold preservation (DEMaP), and show that PHATE produ

235 We define a manifold preservation metric, which we call denoised emb

236 To positively guide the data manifold preservation process, we utilize both labeled a

237 erences, we assessed in vitro the ability of manifold progestins to transactivate zebrafish (zf) and

238 d the preparation of these materials and the manifold properties they possess.

239 confirmed the complex multistep mechanistic manifold proposed by others; however, the formation of a

240 This reaction manifold provides a framework for the catalytic arylatio

241 chieve it, through orchestrated reduction of manifolds' radius, dimensionality and inter-manifold cor

242 These immediate and manifold regulations empower HSF1 to both repress AMPK u

243 n which the kISC magnitude dominates singlet manifold relaxation dynamics but does not give rise to T

244 ng theories that link recurrent circuitry to manifold representation.

245 tes that are 1) consistent with the physical manifold, resulting in physically meaningful predictions

246 Researchers have begun to identify the manifold roles that these cells play in the central nerv

247 We present the self-assembling manifold (SAM) algorithm, an iterative soft feature sele

248 How this low-dimensional manifold scales with cognitive complexity, and which bra

249 A programmable multivalve manifold selects Hg at the analyzer inlet and outlet bas

250 d mechanisms embodied as structured flows on manifold (SFM) that provide a formal description of beha

251 mental quantum annealer samples ground-state manifolds significantly differently than thermal and ide

252 a low-dimensional embedding of a statistical manifold (SM).

253 er free-riders or producers we derive a slow manifold solution.

254 f a superconducting resonator to the quantum manifold spanned by two coherent states of opposite phas

255 acute dengue infection and create a patient manifold, stratifying immune response to dengue.

256 the topology, geometry and dimensionality of manifold structure in such point clouds, we reveal insig

257 We characterize and directly visualize manifold structure in the mammalian head direction circu

258 The manifold symptoms of depression are common and often tra

259 he method involves fitting a one-dimensional manifold that characterizes variation in response timeco

260 al activity converged onto a low-dimensional manifold that facilitates the execution of diverse task

261 e vector fields of class C(1) on a compact 3-manifold that is associated with a well-behaved integral

262 h the adherence junctions of cells form a 2D manifold that is fluorescently labeled.

263 generating a characteristic cell behavioral manifold that is preserved under a perturbation to cell

264 ailed Student's t-distribution to estimate a manifold that is robust to technical and biological nois

265 ondary alcohols in a redox-neutral catalysis manifold that produces water as the sole by-product.

266 oxidation-state-coupled molecular switching manifold that reports its switch-state conformation via

267 ian computational dynamics within the neural manifold that represent the task.

268 The reaction manifold that we report here demonstrates the power of e

269 s has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural

270 ination, and miniaturized 3D printed pumping manifolds that were integrated to enable time-resolved i

271 enerates all feasible structures (structural manifold) that are consistent with these chemical formul

272 ifluoromethyl ketones through a formal [4+2] manifold to access highly enantioenriched dihydrobenzoxa

273 microwave-assisted and base-catalyzed domino manifold to construct 2,4-cyclohexadienone derivatives h

274 w field flow fraction (AF4) using a splitter manifold to enable online particle separation and counti

275 e system on an appropriate flat "Bieberbach" manifold to obtain the filling conditions for all 230 sp

276 photoexcited dye relaxes through the (3)MLCT manifold to the thermally equilibrated state, underscori

277 of possible alternative catalytic modes and manifolds to those already found in nature.

278 functional group via both polar and radical manifolds to unlock a wide array of C-H transformations

279 Then the system contracts stably on this manifold towards its final solution trajectory.

280 serving as formal sources of 1, a reactivity manifold traditionally reserved for transition metals.

281 ontrol and the framework of the uncontrolled manifold (UCM) hypothesis to test two hypotheses: (i) in

282 ges in the geometry of the associated object manifolds underlie this improved capacity, and shed ligh

283 The domino manifold uses easily accessible tertiary propargyl vinyl

284 This mechanistic manifold was previously unknown for this enzyme family,

285 s Euler-Lagrange equations on the Riemannian manifold, was obtained from the principle of least actio

286 mic, and structural details of this reaction manifold were elucidated.

287 tion of alkenes via an I(I)/I(III) catalysis manifold were independently reported by this laboratory

288 We introduce an efficient reaction manifold where the rate of a thermally induced ligation

289 ctivity patterns that span a low-dimensional manifold which remains stable across different environme

290 near deformation of an underlying Riemannian manifold, which is parametrized by a few normalized, lat

291 ollection of discrete clusters and branching manifolds, which constitute strategies spanning life in

292 employed a phase separation/continuous flow manifold whose advantages include catalysis, fast reacti

293 nsider that they trace out a low-dimensional manifold whose dimension and topology match the represen

294 By the same deoxygenation manifold with aliphatic aldehydes and ketones, we also e

295 mbedding the strings in the interior of a 3D manifold with boundary.

296 atalyst and proceeds within an iodine(I/III) manifold with conventional 3-chloroperbenzoic acid as a

297 states within the vibrational and electronic manifold with quantum coherence selectivity.

298 ssion and show how the formation of vibronic manifolds with a high density of states facilitates fast

299 ow, which have been used to decompose smooth manifolds with astonishing successes in mathematics, to

300 find these graphs are navigable only in the manifolds with dark energy.