ライフサイエンスコーパス: mannose receptor

1 rolytic enzymes, are normally cleared by the mannose receptor).

2 (as determined by siRNA gene silencing of AM mannose receptors).

3 Pneumocystis, including dectin-1, TLR2, and mannose receptor.

4 were rapidly cleared from the plasma by the mannose receptor.

5 within the human MRC1 gene that encodes the mannose receptor.

6 in their low association with the macrophage mannose receptor.

7 complement receptors CR1, CR3, CR4, and the mannose receptor.

8 pendent mannose 6-phosphate receptor and the mannose receptor.

9 n-binding lectin, C-reactive protein and the mannose receptor.

10 parable with those found for cell-associated mannose receptor.

11 ycan by CD1b requires antigen uptake via the mannose receptor.

12 brin or the endocytic collagen receptor, the mannose receptor.

13 of trophic forms were not due to ligation of mannose receptor.

14 ocytic collagen receptors uPARAP/Endo180 and mannose receptor.

15 glycans also increases the binding with the mannose receptor.

16 nt upregulated the M2 markers arginase 1 and mannose receptor.

17 nocytosis or cellular entry via scavenger or mannose receptors.

18 upon the efficient uptake of mannoprotein by mannose receptors.

19 different receptors from the complement and mannose receptors.

20 ng their affinities for FimH and eight human mannose receptors.

21 ophages leads to the downmodulation of human mannose receptor 1 (hMRC1), a cell-surface glycoprotein

22 abbing non integrin (DC-SIGN) and macrophage mannose receptor 1 (MMR-1).

23 cterized by expression of arginase-1 (Arg1), mannose receptor 1 (Mrc1), and macrophage scavenger rece

24 We show that mannose receptor 1 (MRC1; CD206) is involved in CpG ODN

25 sis factor alpha, Mx-1, IFNgamma, CXCL9, and mannose receptor 1 gene expression.

26 sh-a2 tumors showed a reduced expression of mannose receptor-1 (CD206), interleukin-10, transforming

27 h early downregulation of surface receptors (mannose receptor-1 (MRC1) and C-type lectins), and subse

28 was characterized by elevated expression of mannose receptor-1, Arginase-1, interleukin-10 and trans

29 pported a role in type 2 diabetes for C-type mannose receptor 2 (MR odds ratio [OR] 0.85 [95% CI 0.79

30 Mannose receptor 2 (Mrc2) expresses an extracellular fib

31 The macrophage mannose receptor, a pattern recognition molecule and com

32 intensity detected by anti-human macrophage mannose receptor Abs, indicating that IL-13, like IL-4,

33 Mannose receptor affinity was unaltered, and mRNA levels

34 ocystis (Pc) organisms predominantly through mannose receptors, although the molecular mechanism medi

35 lecular pathway that links engagement of the mannose receptor, an important pattern recognition recep

36 hese include the antiinflammatory macrophage mannose receptor and arginase-1.

37 ophages expressed C-lectins CD206/macrophage mannose receptor and CD209/DC-SIGN, as well as costimula

38 two key C-type lectin receptors, namely the mannose receptor and DC-specific ICAM 3 nonintegrin at p

39 In addition, both mannose receptor and DEC-205 targeting elicited specific

40 terminus of two human mAbs against the human mannose receptor and DEC-205, both internalizing molecul

41 Multiple receptors including mannose receptor and low-density lipoprotein receptor-re

42 mechanisms including the M-6-P receptor, the mannose receptor and LRP.

43 ukin-10, and macrophage-specific transcripts mannose receptor and S100 calcium-binding protein A9, wh

44 hain, and the scavenger receptors macrophage mannose receptor and sortilin.

45 ectin-1-dependent pathways that involved the mannose receptor and spleen tyrosine kinase.

46 f M. tuberculosis by engaging the macrophage mannose receptor and subsequently binds to intracellular

47 Importantly, competitive inhibition of mannose receptor and targeted short interfering RNA-medi

48 The macrophage mannose receptor and the complement receptor type 3 beta

49 the serum as a consequence of binding to the mannose receptor and/or the asialoglycoprotein receptor

50 Furthermore, the article delves into how mannose receptors and HIV interact, highlighting the pot

51 tyl-<cmd SC>d<cmd /SC> -glucosamine) through mannose receptors and produce IL-12, IL-18, and TNF-alph

52 CD68 (macrophage marker), M2 markers (CD206 (mannose receptor) and CD163 (scavenger receptor)), secre

53 resolution of inflammation, Dectin-1, CD206 (mannose receptor), and IL-4R.

54 ocytosis, reduced expression of MARCO and of mannose receptor, and absent expression of scavenger rec

55 for innate immunity, including MHC class I, mannose receptor, and beta(2)-microglobulin.

56 blocked by saccharides or Abs reactive with mannose receptor, and is dependent upon the state of mat

57 Macrophage mannose, mannose receptor, and scavenger receptors (SR-As) were a

58 ecognition receptors tested (CD11b/CD18, the mannose receptor, and the N-formyl-methionyl-leucyl-phen

59 MUC1 uptake is mediated by the mannose receptor, and the protein is then retained long

60 ion receptors for fungi include dectin-1 and mannose receptor, and these mediate phagocytosis, as wel

61 receptor type 3 (CR3), fibronectin receptor, mannose receptor, and transferrin receptor.

62 ently than N or P by mechanisms depending on mannose receptor- and dendritic cell-specific intercellu

63 monstrate that FDM restricts binding of anti-mannose receptor antibody to macrophages by approximatel

64 ges through glucose transporters and because mannose receptors are expressed on a subset of the macro

65 ll receptor, integrin alphaM, and macrophage mannose receptor, are engaged in N-glycan ligand recogni

66 een after infection and expressed macrophage mannose receptors, arginase-1 activity, and IL-10.

67 m the identification of the CR region of the mannose receptor as a lectin.

68 dhesion molecule-3-grabbing nonintegrin, and mannose receptor as well as inflammatory cytokines.

69 dhesion molecule-3-grabbing nonintegrin, and mannose receptor as well as the inflammatory markers CD6

70 ctor functions, the present study identifies mannose receptors as pattern recognition receptors capab

71 alleles) and mediated predominantly through mannose receptors (as determined by siRNA gene silencing

72 Capture appeared dependent on mannose receptors, as competitive mannosylated inhibitor

73 ly by complement and partially by macrophage mannose receptors, as demonstrated by in vitro assays.

74 erfere with the arrival of newly synthesized mannose receptors at the cell surface, also attenuated m

75 lly resulting in decreased levels of surface mannose receptor available for Ag or pathogen capture.

76 sylation had no effect on the development of mannose receptor binding activity.

77 e studies was to characterize the macrophage mannose receptor binding and pharmacological properties

78 taining the cysteine-rich (CR) domain of the mannose receptor, binds to marginal zone metallophilic m

79 lecule-3 grabbing non-integrin (DC-SIGN) and mannose receptor, bound to FL surface immunoglobulin (sI

80 at sMR was produced by cleavage of an intact mannose receptor by a matrix metalloprotease or ADAM met

81 g are inhibited following PLY binding to the mannose receptor C type 1 (MRC-1) in human dendritic cel

82 ides corti, we have investigated the role of mannose receptor C type 1 (MRC1), a CLR which recognizes

83 PanIN), and resulted in the accumulation of (mannose receptor C type 1) MRC1+, (arginase 1) Arg+ macr

84 th MaR1 showed a significant upregulation of mannose receptor C, type 1 mRNA expression, an M2 macrop

85 resistin-like molecule alpha (Relmalpha) and mannose receptor C-type 1 (CD206), displayed a predomina

86 inity for both the insulin receptor (IR) and mannose receptor C-type 1 (MR), which functions to clear

87 ferator-activated receptor gamma (PPARG) and mannose receptor C-type 1 (MRC1), suggesting that PRMT1

88 he parasite load was reduced in mice lacking mannose receptor C-type 1.

89 macrophages expressing arginase 1 (ARG1) and mannose receptor, C type 1 (MRC1).

90 egfp)(y251) transgenic zebrafish that uses a mannose receptor, C type 1 (mrc1a) promoter to drive str

91 human urine: cadherin 11 (CDH11), macrophage mannose receptor C1 (MRC1), and phospholipid transfer pr

92 Fc chimeras revealed that LRP, DC-SIGN, and mannose receptor can bind to FVIII; however, we did not

93 associated with AA-MPhis (e.g., arginase-1, mannose receptor, CCL2, CCL17, and CCL22).

94 reased alternative M2-like activation marker mannose receptor CD206, yet lack of GLUT1 was not a crit

95 eath ligand-1 (PD-L1), Mac-2, and macrophage mannose receptor (CD206) and producing Klf4, Il10, Retnl

96 s demonstrated a significant increase in the mannose receptor (CD206) and the CD14(+)/CD206(+) double

97 SBP) and quantified the soluble form of the mannose receptor (CD206) and tumor necrosis factor by en

98 mannoprotein was captured by the macrophage mannose receptor (CD206), these data suggest that multip

99 e activation including arginase-1 (ARG1) and mannose receptor (CD206).

100 pressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immuno

101 rotein 10, and IRG1 in macrophages that lack mannose receptor, complement receptors 3 and 4, type A s

102 ns 4-7 and a full-length soluble form of the mannose receptor containing all domains external to the

103 A fusion protein of the mannose receptor containing carbohydrate recognition dom

104 Cysteine-rich (CR) domain of the mannose receptor (CR-Fc)(+) DCs are a newly discovered s

105 ulating CEA was preferentially taken up in a mannose receptor-dependent manner and cross-presented by

106 ce PPARgamma expression through a macrophage mannose receptor-dependent pathway.

107 terns that stimulate TLR2, dectin-1, and the mannose receptor, differentially activate NF-kappaB and

108 ting of soluble exogenous tumor Ag to the DC mannose receptor directly contributes to the generation

109 Mannose receptor dissociation constants (Kd) for pGCR an

110 he HIV-1-derived protein Tat in HIV-mediated mannose receptor down-regulation.

111 The possible involvement of the mannose receptor, either cell surface or soluble, in the

112 macrophages from healthy individuals reduced mannose receptor endocytosis to 53.2% (P < 0.05) and P.

113 lowest levels of P. carinii phagocytosis and mannose receptor endocytosis.

114 minate uptake by the mannose 6-phosphate and mannose receptors exhibits improved circulation time and

115 Mannose receptor expression also was increased on cervic

116 as a model human disease state of reduced AM mannose receptor expression and function) inhibits Pneum

117 HIV infection of AMs (as a model for reduced mannose receptor expression and function) was associated

118 e synthase staining in rodent tissue, and by mannose receptor expression in human breast tissue.

119 ent mechanisms are involved in regulation of mannose receptor expression in these species.

120 mune recognition by the structurally related mannose receptor family and comparison of diverse method

121 ipase A2 receptor (PLA2R) is a member of the mannose receptor family found in podocytes in human kidn

122 f the mammalian phospholipase A2 receptor, a mannose receptor family member, rather than an FcRn or M

123 FcRY shares structural properties with mannose receptor family members, including a head and ta

124 nchymally expressed member of the macrophage mannose receptor family of endocytic receptors, is a key

125 e identification of three new members of the mannose receptor family, additional work on defining the

126 lass of Fc receptor related to the mammalian mannose receptor family.

127 as Endo180 (uPARAP, CD280), a member of the mannose receptor family.

128 In contrast to cDC1, RPM used the mannose receptor for Ag uptake and employed the proteaso

129 competed with the C-type lectins DC-SIGN and mannose receptor for ligand binding and inhibited the bi

130 tron structure was similar to the macrophage mannose receptor gene.

131 n, a preparation that antagonizes macrophage mannose receptors, had minimal effect on TNF-alpha relea

132 Using a mouse model in which the mannose receptor has been deleted, we found that the abs

133 Binding of organisms to beta-glucan and mannose receptors has been shown to stimulate phagocytos

134 ion cloning strategy, the cDNA for the human mannose receptor (hMR) was found to be essential for CD4

135 t of manY corresponds to IIPMan, manZ to the mannose receptor IIBMan, and manX and manW to the single

136 phages, messenger RNA expression of FR-beta, mannose receptor, IL-10, and matrix metalloproteinase-9

137 quirements for sugar binding, a role for the mannose receptor in antigen presentation of lipoglycan a

138 A potential role for the macrophage mannose receptor in human monocyte-derived macrophage fu

139 ligands for the cysteine-rich domain of the mannose receptor in lymph nodes and spleen.

140 nd to investigate the role of the macrophage mannose receptor in mediating this interaction.

141 elated with the levels of CD3 and macrophage mannose receptor in NP tissue.

142 Mannose receptor in the flow-through and eluted fraction

143 eliminated uptake by mannose 6-phosphate and mannose receptors in cultured cells and dramatically slo

144 expression of CD4, CCR5, CXCR4, DC-SIGN, or mannose receptors in tubular cells.

145 s have reduced functions associated with the mannose receptor, including impaired Pneumocystis carini

146 sed to be internalized by cells that express mannose receptors, including macrophages.

147 locked by the addition of mannan, suggesting mannose receptor involvement in the DC-Coccidioides inte

148 of lipoglycan antigens and evidence that the mannose receptor is associated with a signal transductio

149 The macrophage mannose receptor is believed to play an important role a

150 The mannose receptor is expressed on mature macrophages and

151 by mannose-capped lipoarabinomannan and the mannose receptor is independent of TLR2 and NF-kappaB ac

152 lso found that the surface expression of the mannose receptor is not downregulated during P. carinii

153 icate that the well-characterised macrophage mannose receptor is not essential to host defence agains

154 myeloid promoters, transcription of the rat mannose receptor is regulated by binding of PU.1 and a u

155 The mannose receptor is the prototype of a new family of mul

156 Mannose receptor knockout (MR(-/-)) mice lack the abilit

157 sceptible to P. carinii by CD4(+) depletion, mannose receptor knockout mice (MR-KO) had pathogen load

158 manner, which can be blocked by injection of mannose receptor ligands.

159 4GGnM-R is closely related to the macrophage mannose receptor (Man-R) both antigenically and structur

160 e asialoglycoprotein receptor (ASGR) and the mannose receptor (ManR) are expressed in the liver by pa

161 The mannose receptor (ManR, Mrc1) and asialoglycoprotein rec

162 other alternative state (M2)-specific genes (Mannose receptor, MAO-A, and CD36) and therefore conclud

163 These data suggest that the macrophage mannose receptor may be an essential participant in the

164 r findings suggest that while the macrophage mannose receptor may be important in the recognition of

165 lungs, and that impaired alveolar macrophage mannose receptor-mediated binding and phagocytosis of P.

166 Reduced AM mannose receptor-mediated Cdc42 and Rho activation in th

167 ere highly efficient at Ag capture, via both mannose receptor-mediated endocytosis and macropinocytos

168 f-assembled nanocomplexes (SSANs) capable of mannose receptor-mediated endocytosis and permeable to c

169 luorescein isothiocyanate (FITC)-albumin and mannose receptor-mediated endocytosis of FITC-dextran by

170 IL-10 (type 2) cytokines on fluid phase and mannose receptor-mediated endocytosis were assessed by h

171 en uptake: constitutive macropinocytosis and mannose receptor-mediated endocytosis.

172 enhanced cellular uptake of the oligomer via mannose receptor-mediated endocytosis.

173 /mL), rapamycin impairs macropinocytosis and mannose receptor-mediated endocytosis; (2) the effects a

174 The mannose receptor-mediated enhanced cell uptake and high

175 AM mannose receptor-mediated NF-kappaB activation may repre

176 se data provide a molecular mechanism for AM mannose receptor-mediated phagocytosis of unopsonized Pc

177 Taken together, our results indicate that mannose receptor-mediated phagocytosis, but not the rece

178 ptured fluorescent-labeled mannoprotein by a mannose receptor-mediated process.

179 d IL-13 enhanced fluid phase pinocytosis and mannose receptor-mediated uptake by activation of phosph

180 a decreased both fluid phase pinocytosis and mannose receptor-mediated uptake.

181 d Nanobodies directed against the macrophage mannose receptor (MMR) is a useful tool for monitoring a

182 products, whereas the homologous macrophage mannose receptor (MMR), as expected, is found in more pe

183 ster ovary cells expressing human macrophage mannose receptor (MMR), we determined that MP is a MMR l

184 sdAbs) specifically targeting the macrophage mannose receptor (MMR), which has been identified as an

185 chLAL and phLAL were taken up by macrophage mannose receptor (MMR)-positive J774E cells.

186 matory macrophages expressing the macrophage mannose receptor (MMR, CD206) are involved in disease de

187 ypoxic tumor areas highly express macrophage mannose receptor (MMR, CD206).

188 nnosylated LAM (ManLAM) binds the macrophage mannose receptor (MMRc), although the ability of the MMR

189 absent in the related collagen receptor, the mannose receptor (MR or CD206), which consistently does

190 rophage fusion to form FBGC via a macrophage mannose receptor (MR) -mediated pathway.

191 of serum opsonins, competitive inhibition of mannose receptor (MR) activity on MDM with mannan decrea

192 tions, including up-regulation of macrophage mannose receptor (MR) activity.

193 The macrophage mannose receptor (MR) along with complement receptors me

194 Furthermore, antiserum to the mannose receptor (MR) also inhibited HSV, vesicular stom

195 The macrophage mannose receptor (MR) and complement receptor 3 (CR3) ha

196 We investigated the roles of the mannose receptor (MR) and Dectin-2 in resistance to pulm

197 The macrophage mannose receptor (MR) and dendritic cell-specific ICAM-3

198 ound and internalized via its glycans by the mannose receptor (MR) and subsequently impairs protein s

199 The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and

200 The mannose receptor (MR) binds foreign and host ligands thr

201 The pattern recognition mannose receptor (MR) binds to the ManLAM mannose caps a

202 ptor with collagenous structure (MARCO), and mannose receptor (MR) have been identified as nonopsonic

203 ain, by human macrophages is mediated by the mannose receptor (MR) in addition to complement receptor

204 To examine the role of the mannose receptor (MR) in glycoprotein clearance, we gene

205 We investigated how innate sensing by the mannose receptor (MR) influences the development of anti

206 The mannose receptor (MR) is a transmembrane protein that fu

207 The mannose receptor (MR) is an endocytic receptor involved

208 The mannose receptor (MR) is known to be involved in the rec

209 Antisense oligodeoxynucleotide (ODN) to mannose receptor (MR) mRNA inhibited the expression and

210 ficantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood monon

211 Recombinant lectin domains of the mannose receptor (MR) or DC-SIGN bind mannosylated Igs i

212 Members of the well-conserved mannose receptor (MR) protein family have been functiona

213 MSCs also expressed mannose receptor (MR) that was found to endocytose rhoda

214 fied antibodies redirected bacteria from the mannose receptor (MR) to the complement receptor CR3, th

215 The macrophage mannose receptor (MR) was responsible for uptake of LAM.

216 -derived macrophages (BMDMs) in vitro and by mannose receptor (MR)(hi) dermal macrophages in vivo com

217 The mannose receptor (MR), a carbohydrate-binding receptor e

218 art, to increased activity of the macrophage mannose receptor (MR), a pattern recognition receptor fo

219 We demonstrate that the mannose receptor (MR), a type I transmembrane protein, i

220 t of a carbohydrate receptor, the macrophage mannose receptor (MR), and its role in supporting HIV-1

221 MP is its capacity to bind to the conserved mannose receptor (MR), CD206, on dendritic cells (DCs).

222 one marrow-derived macrophages isolated from mannose receptor (MR), complement receptor 3 (CR3), MyD8

223 ular, C-type lectin receptors, including the mannose receptor (MR), facilitate APC-mediated adsorptiv

224 Here, we report that the macrophage mannose receptor (MR), is a restriction factor targeting

225 , such as the C-type lectin immune receptors mannose receptor (MR), macrophage galactose lectin (MGL)

226 In particular, mannose receptor (MR), through modulation of Toll-like r

227 Mannose receptor (MR)-dependent uptake and lysosomal tar

228 Mannose receptor (MR)-null myotubes were small in size a

229 osclerotic plaque areas enriched in CD68 and mannose receptor (MR)-positive (CD68(+)MR(+)) alternativ

230 requires the interaction of ManLAM with the mannose receptor (MR).

231 lipoarabinomannan (ManLAM) to the macrophage mannose receptor (MR).

232 for zymosan that was distinct from the Mphi mannose receptor (MR).

233 blocking mAb directed toward the macrophage mannose receptor (MR).

234 proteins: macrophage receptors, such as the mannose receptor (MR, CD206), dendritic cell-specific IC

235 at have high expression of the C-type lectin mannose receptor (MR; CD206).

236 ionally, competitive blockade of multilectin mannose receptors (MR) on APCs diminished MP-dependent s

237 nzyme with exposed mannosyl residues targets mannose receptors (MR) on macrophages, ERT targets prima

238 ss several cell surface receptors (e.g., the mannose receptor, MR) that may serve as drug delivery ce

239 Macrophage mannose receptor (MRC) is one of the few molecules known

240 Genetic ablation of the collagen receptors mannose receptor (Mrc1) and urokinase plasminogen activa

241 on C-type-lectin receptors (CLRs), including mannose receptor (MRC1; CD206), have been suggested to f

242 interfering RNA-mediated gene suppression of mannose receptor mRNA and protein is associated with com

243 nt vaccine immunogenicity by targeting Ag to mannose receptors (MRs) on dendritic cells.

244 s, mannose-receptor positive macrophages and mannose-receptor negative myeloid cells.

245 The mannose receptor of macrophages and liver endothelium me

246 nnosides, they are also potential ligands of mannose receptors of the human host system.

247 increases uptake of soluble IgG mediated by mannose receptor on macrophages and dendritic cells.

248 or (CD206), these data suggest that multiple mannose receptors on DC recognize mannoprotein.

249 in pathogenesis, either by interaction with mannose receptors on host cells, or as targets or modula

250 or intra-endosomal degradation compared with mannose receptor or DEC205.

251 l interfering RNA-mediated knockdown of LRP, mannose receptor, or DC-SIGN expression in monocyte-deri

252 arbohydrate remodeling improved targeting to mannose receptors over native enzyme by two orders of ma

253 crophages, although a higher proportion were mannose receptor positive, a characteristic of different

254 redominance of two hematopoietic cell types, mannose-receptor positive macrophages and mannose-recept

255 tion of CCL18 in CD68(+)/CD163(+)/macrophage mannose receptor-positive M2 macrophages and tryptase-po

256 s exposed to red cells showed an increase in mannose receptor-positive macrophages only when these ce

257 an alternative phenotype being both CD68 and mannose receptor-positive, expressing carbonic anhydrase

258 /reperfusion injury, whereas arginase 1- and mannose receptor-positive, noninflammatory (M2) macropha

259 sistent with a mechanism whereby Tat reduces mannose receptor promoter activity by interfering with t

260 nstruct of USF resulted in a 50% decrease in mannose receptor promoter activity, further establishing

261 ter construct resulted in down-regulation of mannose receptor promoter activity.

262 tion factors Sp1, PU.1, and USF bound to the mannose receptor promoter, but only PU.1 and USF contrib

263 line U937 with a Tat expression vector and a mannose receptor promoter-luciferase reporter construct

264 t the isolation of 854 base pairs of the rat mannose receptor promoter.

265 ishing the role of USF in activating the rat mannose receptor promoter.

266 DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endoc

267 5, thereby illuminating the structure of the mannose receptor protein family.

268 The mannose receptor recognizes the patterns of carbohydrate

269 By leveraging the unique properties of mannose receptors, researchers can design drug delivery

270 , most of the macrophages expressed CD206, a mannose receptor responsible for removing inflammatory m

271 Cells lacking mannose receptors showed no susceptibility to the conjug

272 t defence: phagocytic receptors, such as the mannose receptor, signal particle internalization, and t

273 A soluble form of the mannose receptor (sMR) has been found in conditioned med

274 Here, we demonstrate that the soluble mannose receptor (sMR) plays a direct functional role in

275 s C, 95% of the total macrophage binding was mannose receptor specific.

276 The macrophage mannose receptor specifically recognizes proteins and pa

277 polysaccharide structure and binding to the mannose receptor, suggesting that polysaccharide conform

278 strated up to an 80% (P < 0.05) reduction in mannose receptor surface expression and endocytosis.

279 Mannose receptor synthesized by cells incubated in brefe

280 n vivo experiments in mice revealed that the mannose receptor system on macrophages also participates

281 an BDCA1+ and monocyte-derived DCs, CD40 and mannose receptor targeted antibody conjugates to early e

282 to macrophages by approximately 35% and that mannose receptor targeting may provide an additional ave

283 have generated a human mAb (B11) against the mannose receptor that is rapidly internalized by DCs thr

284 ted number of phagocytic receptors, like the mannose receptor, that recognize conserved motifs on pat

285 expose terminal mannose residues and target mannose receptors, the uptake of this modified enzyme fo

286 The in vitro binding of the macrophage mannose receptor to a range of different bacterial polys

287 that binding of type 1 fimbriae (pili) to d-mannose receptors triggers a cross talk that leads to do

288 n mannose-binding protein and the macrophage mannose receptor, two mammalian C-type lectins, bind to

289 ulated in culture, whereas macrophage genes, mannose receptor type-1, Cd68, serum amyloid-A3, chemoki

290 We conclude that the mannose receptor undergoes delayed activation following

291 The full-length soluble form of the mannose receptor was able to bind simultaneously both po

292 The mannose receptor was also not involved with invasion aft

293 Labeled mannose receptor was found exclusively in the nonbinding

294 that exploits endocytosis via the macrophage mannose receptor was used.

295 that exploits endocytosis via the macrophage mannose receptor, was constructed and complexed to expre

296 in inflammatory zone 1, Ym1, and macrophage mannose receptor were observed in the lungs of mice infe

297 antigen was chemically deglycosylated or if mannose receptors were blocked with mannans.

298 Mannose receptors were confirmed to be specifically up-r

299 on of strongly adherent bacteria by blocking mannose receptors with a soluble inhibitor actually incr

300 y for uptake of exogenous LPLA(2) is via the mannose receptor, with subsequent translocation into aci