ライフサイエンスコーパス: markedly reduce

1 ding was shortened, and clinical disease was markedly reduced.

2 variability and the frequency of TA use were markedly reduced.

3 PLEX B nuclear genes LHCB1.2 and LHCB2.3 was markedly reduced.

4 t that the TLR4 agonist activity of OMVs was markedly reduced.

5 ayer and axon number in the optic nerve were markedly reduced.

6 absent, both colonization and virulence were markedly reduced.

7 phosphorylation in patients' lymphocytes was markedly reduced.

8 proliferation and survival of CRPC cells is markedly reduced.

9 in 2 in lesional skin of these patients were markedly reduced.

10 Levels of Abeta peptides and plaques were markedly reduced.

11 medium from Hdac3-deficient osteoclasts was markedly reduced.

12 ce of the lon-2 mutant to osmotic stress was markedly reduced.

13 vitro and resistance to osmotic pressure was markedly reduced.

14 n contrast, the rate of SSB repair (SSBR) is markedly reduced.

15 At 5 degrees C measured CO2.a was markedly reduced (0.025) and 60% lower than TBM estimate

16 neurons in the presence of astrocytes showed markedly reduced AbetaO binding and synaptopathy.

17 The Y315A mutant also showed a markedly reduced ability to assemble into viral particle

18 the absence of either alphakap or alpha-dbn markedly reduces AChRalpha accumulation and that overexp

19 s using electron transfer dissociation (ETD) markedly reduced adduct loss.

20 In addition, the absence of NAMPT in WAT markedly reduced adrenergic-mediated lipolytic activity,

21 sening HF or diagnosed with new-onset HF was markedly reduced after lockdown but has not yet impacted

22 ith Chlamydia, CCR7-deficient mice displayed markedly reduced Ag-specific CD4 T cell responses within

23 ed, effectively blocking HIV replication and markedly reducing AIDS morbidity and mortality.

24 ministration of exogenous recombinant Sema3E markedly reduced allergen-induced neutrophil recruitment

25 Furthermore, water intake was markedly reduced, ameliorating the symptoms of diabetes

26 epsilonRI, and administering asialylated IgE-markedly reduce anaphylaxis.

27 Total daily activity was markedly reduced and rest-activity rhythmicity was undet

28 of either PspA or PspC, C4BP deposition was markedly reduced, and there was a corresponding reductio

29 actor Xa inhibitor, treatment with andexanet markedly reduced anti-factor Xa activity, and 82% of pat

30 , miR-346, miR-361-3p and miR-197 inhibitors markedly reduced AR transcriptional activity, mRNA and p

31 ssion of both the mutant SDR9C7 proteins was markedly reduced as compared to wild-type protein, sugge

32 deletion in mice, acute ATF6alpha knockdown markedly reduced ATF6-pathway target gene expression und

33 t a rigid IS6-alpha-interaction domain helix markedly reduced basal open probability despite intact b

34 isplatin together, but not as single-agents, markedly reduces BC growth and metastasis.

35 HepG2 cells with the most promising receptor markedly reduced beauvericin-induced cytotoxicity, hinti

36 The resultant antigen shows markedly reduced binding to mAbs that target the head re

37 All three compounds markedly reduced biopsy-based relative liver lipid conte

38 istration of a HIF activator in clinical use markedly reduced bone marrow and transitional B cells, w

39 and found they were smaller in size and have markedly reduced bone mass compared to WT.

40 proregenerative phenotypes at the injury and markedly reduced both fibrotic and gliotic scarring 3-fo

41 binant AAV-mediated transgene expression was markedly reduced, both in vitro and in vivo.

42 hin dimer known as proanthocyanidin B2) that markedly reduced brain plaque load and improved short-te

43 (Pf4) promoter generated megakaryocytes with markedly reduced but not absent Scl These Pf4Sclc-KO mic

44 lizing capacity of individual antibodies was markedly reduced but this was largely compensated for by

45 tem cells to forebrain neural progenitors is markedly reduced, but mutant progenitor cells can genera

46 time we demonstrate that spindle density is markedly reduced by (i) optogenetic stimulation of a maj

47 and migration, and that these activities are markedly reduced by ACTL6A knockdown.

48 te hypercapnic acidosis (pH 7.4 to ~7.2) was markedly reduced by antagonists of 5-HT(7) receptors.

49 However, tumor growth was markedly reduced by cotreatment with sorafenib and adeno

50 tentiation of ATP responses by CK and Rd was markedly reduced by mutations S59A, S60A, D318L and L320

51 ected farms; and more importantly, it can be markedly reduced by swift depopulation and inlet air fil

52 response of RTN neurons in brain slices was markedly reduced by the same antagonists of 5-HT(7) rece

53 ht phase centred on ca. 1.8-1.1 ka BP led to markedly reduced C accumulation and potentially a hiatus

54 Nanomolar concentrations of C1572 markedly reduced c-MYC (MYC) protein levels via a protea

55 2L; numbered including the start-Met), which markedly reduces CaM Ca(2+) binding.

56 d to matriptase was that hepsin demonstrated markedly reduced capacity to activate proteinase-activat

57 , with FXXN motifs replaced by SXXV, shows a markedly reduced capacity to form oligomers.

58 id anti-miRNA inhibitors of these six miRNAs markedly reduced cardiac RNA-induced cytokine production

59 ion and competitive fitness, associated with markedly reduced CD25 expression and interleukin-2 (IL-2

60 troduce steric strain in the open state show markedly reduced CD4 interactions.

61 Forced expression of ZFP36L1 in cancer cells markedly reduced cell proliferation in vitro and in vivo

62 This Ca(2+) depletion was followed by markedly reduced cell proliferation rates and morphologi

63 mal maturation in the Golgi complex and show markedly reduced cell-surface expression.

64 body against the GlcFuc disaccharide, and in markedly reduced cellular levels of MIC2.

65 f N-acetylglucosaminyl transferase I (Mgat1) markedly reduced cellularity in the bone marrow and/or s

66 ducts with excellent coverage uniformity and markedly reduced chimerism compared with products of liq

67 c microglia after TBI using CSF1R inhibitors markedly reduce chronic neuroinflammation and associated

68 tease compromised VAC digestive function and markedly reduced chronic infection.

69 and mice expressing human APOC3 A43T display markedly reduced circulating apoC-III levels.

70 ction of functional BLA by commensal E. coli markedly reduced clearance of these pathogens and enhanc

71 we believe that this new reaction may allow markedly reduced click-to-release reagent doses in vitro

72 Disrupting various cell adhesion genes markedly reduces cluster formation and colonization effi

73 Mutations of C/G in this motif markedly reduced Col3a1 transcriptional regulation by PT

74 tic SOD1(G93A) mice, axonal regeneration was markedly reduced compared to presymptomatic SOD1(G93A) m

75 e as WT channels; however, their current was markedly reduced compared to WT TASK-1 channels.

76 We found a markedly reduced conducted vasodilation both in obese ZS

77 io (LPR), glutamate; decreased glycerol) and markedly reduced cord inflammation (reduced IL1beta, IL8

78 tors, perfused through microdialysis probes, markedly reduced cortex susceptibility to CSD, but also

79 ex that mediates neutrophil oxidative burst, markedly reduced CXCL1-induced NASH and stress kinase ac

80 l kinase inhibition and NF-kappaB inhibition markedly reduced cyclobutane pyrimidine dimers-positive

81 educed tyrosine phosphorylation of STAT3 and markedly reduced cystic growth of human and mouse ADPKD-

82 Suboptimal coverage markedly reduced DALYs averted and cost-effectiveness.

83 nhanced encephalographic slow-wave activity, markedly reduced diffuse axonal damage in the cortex and

84 Depletion of CD11c(+) cells markedly reduced disease severity due to impaired enrich

85 Surface diffusion is also markedly reduced due to clustering of the molecules at t

86 strated that plasma clearance of cortisol is markedly reduced during critical illness, explained by s

87 -6, and TNFalpha in the lungs and liver were markedly reduced during endotoxemia in IL-37Tg mice but

88 dularity-a measure of network segregation-is markedly reduced during episodic memory retrieval relati

89 activating factor acetylhydrolase 2 (PAFAH2) markedly reduced EC dysfunction induced by CM, whereas P

90 The nicking of the plasmid results in markedly reduced efficiencies in transformation of E. co

91 TRC-cleaved mesotrypsin degraded SPINK1 with markedly reduced efficiency.

92 ion, a reduction in histological injury, and markedly reduced elaboration of cardiac troponin-I in co

93 etion of this element in cultured human SMCs markedly reduced endogenous ARHGAP42 expression.

94 xcessive production of red blood cells, have markedly reduced endothelial function.

95 C12 + Trp markedly reduced energy intake (kcal; control: 1,232 +/-

96 Heterozygous carriers have a markedly reduced enzyme activity when compared to wild-t

97 in NCKX4(-/-);CNGB1(DeltaCaM) mice displayed markedly reduced EOG amplitude accompanied by alteration

98 se DDI-1-dependent degradation, resulting in markedly reduced expression at presynaptic terminals.

99 s that are induced during quiescence despite markedly reduced expression of Exportin-5, a protein req

100 dentified a rare subpopulation of cells with markedly reduced expression of NME1 (NME1(LOW)) in human

101 ibits xenograft cancer growth accompanied by markedly reduced expression of TNBC signature genes.

102 were virtually absent in cones and displayed markedly reduced F-actin content in rods, suggesting tha

103 ) mice displayed normalized estrogen levels, markedly reduced fat accumulation, and improved glucose

104 Adipocyte-specific deletion of Angpt2 markedly reduced fatty acid uptake and storage in SAT, l

105 RVXB markedly reduced fibrin deposition, suggesting reduced i

106 and phagocytic cup formation, but displayed markedly reduced filopodia formation.

107 orrect chromatic aberration also suffer from markedly reduced focusing efficiency.

108 Ars2 association with chromatin is markedly reduced following NSC differentiation.

109 arse graining, though connectivity was still markedly reduced for this ensemble type with coarse grai

110 rom stage 0 through 4, and (2) SGII(VIP) was markedly reduced from stage 1 to 2.

111 in platelet-leukocyte complex formation and markedly reduced generation of factor Xa and thrombin on

112 nistic studies revealed that CDK7 inhibition markedly reduces glutathione levels and increases reacti

113 n reduced Gp130 palmitoylation and even more markedly reduced Gp130 surface expression, potentially e

114 plete fistula resolution in 9 patients and a markedly reduced gracile fistula in the remaining patien

115 Notably, sTLR2 treatment markedly reduced Gram-positive and -negative bacteria-in

116 Structurally, FlgHrnr(-/-) mice displayed a markedly reduced granular layer and a condensed cornifie

117 MITF.KO cells showed markedly reduced growth and invasion in vitro, and were

118 We found that microbial metabolism markedly reduces gut pH and redox potential through the

119 ell line p.Leu333SerfsTer4 expression showed markedly reduced HAO1 protein levels and cellular protei

120 dose of EPCR-blocking monoclonal antibodies markedly reduced hemophilic synovitis in FVIII-/- mice s

121 oplasmy across all cell types but also found markedly reduced heteroplasmy in T cells, a finding cons

122 F573 markedly reduced human and mouse islet apoptosis after i

123 The pan-caspase inhibitor F573 markedly reduces human and mouse islet apoptosis and imp

124 Benefits would nonetheless be markedly reduced if most people do not adhere to these m

125 In purified stimulated human B cells, 9cRA markedly reduced IgE production and enhanced IgA product

126 We demonstrate that EPIT markedly reduced IgE-mediated allergic reactions in a mo

127 HER2 receptors expression were markedly reduced in 5-FU-SLN(4) treated mice compared wi

128 C6) and the related family member HDAC10 are markedly reduced in adipose tissues of obese animals and

129 However, these abnormalities were markedly reduced in aging Nox2KO brains.

130 ymes that phosphorylate sphingoid bases, was markedly reduced in both NPC1 mutant and NPC1 knockout c

131 Notably, proliferation was markedly reduced in breast biopsies from BRCA1-mutation

132 rogated in FcRgamma chain-deficient mice and markedly reduced in C5aR1-deficient mice.

133 natural killer T cells and neutrophils were markedly reduced in ConA-treated HSC-depleted mice compa

134 luenzae disease, and its prevalence has been markedly reduced in countries that have implemented vacc

135 protein expression and caveolae numbers were markedly reduced in ECs from EphB1-deficient (EphB1(-/-)

136 ly absent in preimplantation embryos and are markedly reduced in fate-committed lineages.

137 necessary for clearing damaged myelin, were markedly reduced in GALC +/- animals.

138 rong AHR and airway inflammation, which were markedly reduced in HFD-fed mice.

139 as well as hepatic MPhi IL-6 expression were markedly reduced in HIF-2alpha(mye/-) mice compared to w

140 LKB1 expression was markedly reduced in human plaques when compared with non

141 osphine oxide-1-sensitive K(+) currents were markedly reduced in isolated vascular smooth muscle cell

142 ere we show that the K(Ca)-sAHP component is markedly reduced in male rat epileptic neurons, whereas

143 genesis and luminal cell differentiation, is markedly reduced in mammary epithelial cells of transgen

144 t thapsigargin and thrombin-induced SOCE was markedly reduced in Mylk-L(-/-) endothelial cells (EC) o

145 PRIM1 protein levels were markedly reduced in patient cells, accompanied by replic

146 ffect of pKa on the rate of dark recovery is markedly reduced in PixD.

147 n contrast, although GC B cell formation was markedly reduced in SAP-deficient NOD mice, T cells with

148 ebpalpha and C/ebpbeta mRNA and protein were markedly reduced in Src-1/-2 double-deficient (Src-1/-2(

149 ased toward term in lungs of WT fetuses, was markedly reduced in Src-1/-2(d/d) fetal lungs.

150 /lew) mice; (2) synaptic vesicle density was markedly reduced in Syb1(lew/lew)Syb2 (-/-) NMJs; and (3

151 ) NMJs; and (3) evoked neurotransmission was markedly reduced in Syb2 (-/-) NMJs and completely aboli

152 PD-1 and CTLA-4 expression was significantly markedly reduced in T cells by both agents.

153 The CCDC3 expression is markedly reduced in TAp63-null mouse embryonic fibroblas

154 damage or by PLK4 or CDK2 overexpression was markedly reduced in the absence of C-NAP1.

155 ls and the total number of Gr1(+) cells were markedly reduced in the bone marrow, along with an incre

156 Unexpectedly, plasma BMP10 levels were also markedly reduced in these individuals.

157 SIRT6 protein, but not mRNA, expression was markedly reduced in VSMCs in human and mouse atheroscler

158 by one of the three distinct mechanisms: (i) markedly reducing IN levels thus precluding the formatio

159 n by occlusion of the middle cerebral artery markedly reduced infarct size, and this correlated with

160 n vitro, in which deletion of gL resulted in markedly reduced infectivity.

161 In both patient groups, we report a markedly reduced influence of previous stimuli on workin

162 Substitution of the Lys residues to Glu markedly reduced integrin binding of E128K IL-1beta, sug

163 Section of the corpus callosum markedly reduced interhemispheric functional connectivit

164 nses in the mirroring M1 and cerebellum, and markedly reduced interhemispheric inhibition.

165 Intestine HIF-2alpha inhibition markedly reduced intestine and serum ceramide levels.

166 , CCR2 deficiency in mdx(5cv)-Ccr2(-/-) mice markedly reduced intramuscular Ly6C(hi) MPs at all stage

167 of cationic proteins from bovine lactoserum markedly reduced its capacity to induce sIgE.

168 icantly increased the half-life of PIM1, and markedly reduced its ubiquitylation.

169 out-of-hospital cardiac arrest do not have a markedly reduced left ventricular ejection fraction.

170 of the PVT1 gene, as a circular RNA showing markedly reduced levels in senescent fibroblasts.

171 ranasal instillation of the allergen induced markedly reduced levels of airway eosinophils, CD4(+) ly

172 ng, mutants of some of these genes exhibited markedly reduced levels of eDNA and a concomitant reduct

173 tion required for antibody functionality and markedly reduced levels of endotoxin contamination.

174 ipose triglyceride lipase (ATGL), as well as markedly reduced lipid droplet size.

175 Here we show that a diverse microbiota markedly reduces Listeria monocytogenes colonization of

176 ich are highly expressed by retinal neurons, markedly reduced loss of neurons and optic nerve axons i

177 protein convertase subtilisin/kexin type 9), markedly reduces low-density lipoprotein cholesterol acr

178 L model with a short course of anti-CD47 mAb markedly reduced lymphoma burden and extended survival.

179 g METTL14 knockdown, H3K36me3 depletion also markedly reduces m(6)A abundance transcriptome-wide and

180 ted with suppressed mast cell activation and markedly reduced mast cell infiltration into the small i

181 led to impaired mitochondrial function, with markedly reduced maximum respiration rate, reserve respi

182 Ablation or inhibition markedly reduces mechanical but not acute chemical itch

183 his uptake resulted in enhanced survival and markedly reduced metastasis.

184 uN2A(N615K) -containing triheteromers showed markedly reduced Mg(2+) blockade, with a value intermedi

185 ologically important receptor properties: it markedly reduces Mg(2+) blockade and channel conductance

186 SF-PreCon markedly reduced MI/R injury in DM mice, as evidenced by

187 induces metabolic changes in beta-cells that markedly reduce mitochondrial metabolism and ATP synthes

188 Metformin treatments markedly reduced mitochondrial fragmentation, mitigated

189 ion of the MCP1-CCR2 chemoattractant pathway markedly reduced monocytic infiltrates, perineuronal net

190 ciated with significant organ protection and markedly reduced mortality compared with nontreated cont

191 Anti-CTLA4 DVD markedly reduced multiorgan immune toxicity by preservin

192 Treatment of infected zebrafish with aspirin markedly reduced mycobacterial burden.

193 creased expression of Atrogin1 and MuRF1 and markedly reduced MyoD.

194 accelerate decomposition of S-nitrosothiols, markedly reduced NADPH diaphorase staining in tissue sec

195 rosis factor-alpha (TNF-alpha) secretion and markedly reduced neuronal viability compared with neuron

196 Postinjury inflammation markedly reduces newborn neuron survival.

197 e, UUO-treated IL-36 knockout mice exhibited markedly reduced NLRP3 inflammasome activation and macro

198 In contrast, mice that have markedly reduced numbers of nonclassical monocytes (CX3C

199 e E64K ground-state stabilizing substitution markedly reduced or ablated soluble CD4 (sCD4) induction

200 us, amaurotic pupils, oculo-digital sign and markedly reduced or absent electroretinograms (ERG).

201 Compared with placebo, DMT markedly reduced oscillatory power in the alpha and beta

202 These surface substitutions markedly reduce oxygen affinity and even confer cooperat

203 mia, metabolic clearance rate of insulin was markedly reduced (P < 0.01).

204 which creates a carbon-centered radical that markedly reduces parasite density.

205 e VSV, the highly attenuated virus displayed markedly reduced pathogenesis but induced similar MHBs-s

206 ients with anaphylaxis were characterized by markedly reduced PGE(2) levels vis-a-vis healthy subject

207 iant cells (GCs) within the junctional zone, markedly reduced placental serotonin (5-HT) concentratio

208 ubfractions; at either A3GALT2 or NRG4, with markedly reduced plasma insulin C-peptide concentrations

209 A subset of patients with PAH had markedly reduced plasma levels of BMP9 and BMP10 in the

210 Laparoscopy has been associated with markedly reduced postoperative pain but has not been wid

211 Partial model calibration (stages 2-4) markedly reduced prediction errors of the full model ens

212 r agonist after vasculopathy was established markedly reduced progression of arterial occlusion in mi

213 Adiponectin knock-out mouse colons had markedly reduced proliferation and increased epithelial

214 Surprisingly, PF74 markedly reduced proviral integration owing to inhibitio

215 meostasis by farnesoid X receptor activation markedly reduces PTB and dramatically improves newborn s

216 he AT2 stem cell population, Etv5 deficiency markedly reduced recovery following bleomycin-induced lu

217 and clofarabine treatments (38% +/- 3) but a markedly reduced relapse rate (44% +/- 3 vs 35% +/- 3) i

218 acterization of these mutations demonstrated markedly reduced remodeling activity.

219 Acetate had similar effects and markedly reduced renal fibrosis.

220 reated proteinuric rats, paricalcitol showed markedly reduced renal lymphangiogenesis.

221 ess than 5% of the total) representing touch markedly reduced responses in the spared touch represent

222 ochondrial motility in pcd neurons and noted markedly reduced retrograde axonal transport.

223 CRT was associated with markedly reduced risk of heart transplant or death (haza

224 Both groups had markedly reduced rod and cone responses, but nonsyndromi

225 The results indicate that there is markedly reduced RPE atrophy progression in areas co-loc

226 ta indicate that exposure to house dust mite markedly reduces Sema3E expression in mouse airways.

227 sitive predictive value for incident TB, but markedly reduces sensitivity.

228 The AAV treatment markedly reduces SLN expression, attenuates muscle patho

229 Administration of recombinant BMP4 markedly reduced spontaneous metastasis to lung and bone

230 For example, S180A knock-in mice showed markedly reduced spontaneous tumorigenesis and increased

231 ation of Srebf-2 in hepatocytes of mice also markedly reduced SREBP-1c and the expression of all gene

232 noid-derived epithelial monolayers expressed markedly reduced ST6Gal-I and underwent TNF-induced, cas

233 ion of the Th17 cell-inducing gut microbiota markedly reduces stress-induced VOEs.

234 Branching deficiency markedly reduced surface expression of the pre-BCR/BCR c

235 restin2 mutants acting as dominant-negatives markedly reduces tau-laden neurofibrillary tangles in FT

236 A point mutation in this motif markedly reduces TF-FVIIa association with integrins, at

237 of potent selective AR degraders (SARD) that markedly reduce the activity of wild-type and splice var

238 tegrated quantum optics has the potential to markedly reduce the footprint and resource requirements

239 tion of both signaling pathways was shown to markedly reduce the metastatic lesions in established lu

240 intestinal UPEC reservoirs, mannosides could markedly reduce the rate of UTIs and recurrent UTIs.

241 Finally, the presence of ApN markedly reduced the activity of NF-kappaB, a key player

242 hain for activation, phosphorylation of Rlc1 markedly reduced the affinity of Myo2 for actin.

243 tions in the predicted integrin-binding site markedly reduced the binding of alpha5beta1 to CD40L.

244 Moreover, depletion of ATG7 markedly reduced the binding of RelA/p65 to DNA in the n

245 ectrophysiology-guided cardiac radioablation markedly reduced the burden of ventricular tachycardia.

246 itters GABA or glutamate within this circuit markedly reduced the capacity for prolactin action both

247 Blockade of CD80/CD86 with CTLA-4-Ig markedly reduced the cycling and absolute numbers of MP

248 phosphorylation site for basophilic kinases, markedly reduced the endocytosis, whereas phosphomimetic

249 The restriction starch hydrolysis rate markedly reduced the GI of biscuits.

250 etic (NOD) mice delayed the onset of T1D and markedly reduced the incidence of T1D, whether PAHSAs we

251 IL-4 treatment markedly reduced the infiltration of CD8(+) T cells and

252 linker between cap helix 2 and pore helix 1, markedly reduced the inhibitory effect of IBMX.

253 EV therapy also markedly reduced the large renal transcriptome drift obs

254 lly, bosutinib, a tyrosine kinase inhibitor, markedly reduced the level of YAPY357 and the developmen

255 adhesion complex (FAC) proteins, where VopA markedly reduced the levels of focal adhesion kinase (FA

256 Furthermore, CXCR6 deficiency markedly reduced the number of macrophages and T cells i

257 knockout (KO) of p32 in PCV2-infected cells markedly reduced the phosphorylation of PKC-delta and im

258 eletion of Tgfbr1/2 or Smad3, but not Smad2, markedly reduced the pressure overload-induced fibrotic

259 f severe pericardial adhesions, the hydrogel markedly reduced the severity of the adhesions, whereas

260 The deficiency of Flna in macrophages markedly reduced the size of aortic atherosclerotic plaq

261 Low dose Amiodarone markedly reduced the size of GBM xenograft tumors and di

262 or of the U1 snRNP protein component SNRNP70 markedly reduces the chromatin association of hundreds o

263 ion, and activity and that PFKFB3 inhibition markedly reduces the EGF-mediated increase in glycolysis

264 icated that knockdown of endogenous DARPP-32 markedly reduces the expression of CD44 V8-V10 (CD44E).

265 Global deletion of Txndc5 markedly reduces the extent of PF and preserves lung fun

266 POLD2 depletion markedly reduces the frequency of translocations with se

267 he green fluorescent protein-coding sequence markedly reduces the levels of gfp mRNA expression in S.

268 study suggests that education in early life markedly reduces the probability of cognitive impairment

269 Pouch formation markedly reduces the risk of dumping syndrome at 3 to 6

270 inistration of free PEG alone was capable of markedly reducing the APA response to PEG-liposomes for

271 ntum state at ultralow temperatures, thereby markedly reducing the number of exit channels accessible

272 proves detection of high-risk patients while markedly reducing the number of HVPG measurements requir

273 ingly, withholding amino acids from the diet markedly reduces their availability in the gut lumen.

274 d compared with controls, the knock-outs had markedly reduced thyroxine levels ( approximately 50-80%

275 Blocking CD28-dependent signaling markedly reduced tissue-infiltrating T cells and effecti

276 ncy of the lesion, the bypass efficiency was markedly reduced (to 1-10%) in the isogenic cells defici

277 BCNPs have superior therapeutic efficacy and markedly reduced toxicity as compared to the nontargeted

278 ) of Micu2(-/-) ventricular tissues revealed markedly reduced transcripts encoding the apelin recepto

279 pted overall complementarity to the 18S rRNA markedly reduced TriMV IRES activity, as did the deliver

280 Importantly, CPT-loaded alphaDR5-NPs markedly reduced tumor growth rates in vivo in establish

281 In a 4T1 tumor model, DeltaN146 markedly reduces tumor growth and metastasis formation.

282 pressing CRPC cell line and xenograft models markedly reduces tumor growth through inhibition of mTOR

283 at positions 306 and 314 (termed M1 and M7) markedly reduced V3 antigenicity while improving the pre

284 mosquitoes infected with these strains show markedly reduced vector competence.

285 ded cardiac radioablation is associated with markedly reduced ventricular arrhythmia burden with mode

286 of mouse Ldlrad3 or human LDLRAD3 results in markedly reduced viral infection of neuronal cells, whic

287 led to induce host alkalinization and showed markedly reduced virulence in tomato plants, while elici

288 After 28 days of treatment, dogs have markedly reduced waist circumference, body weight, and f

289 lung at 5 days postinfection (p.i.) and had markedly reduced weight loss, pulmonary inflammatory cel

290 ll currents at negative potentials, although markedly reduced, were still carried by sodium.

291 , bacterial resistance to osmotic stress was markedly reduced when lon-1 was inactivated.

292 the right anterior insula and amygdala were markedly reduced when participants received painful ther

293 ; the percentage of intron retention (IR) is markedly reduced whereas that of alternative acceptor si

294 nd the relative abundance of Firmicutes were markedly reduced, whereas Proteobacteria were enriched i

295 ined for centuries by traditional practices, markedly reduced while the number of woody species, asso

296 The intraepidermal nerve fibre density was markedly reduced with 90.5% of participants having a cou

297 hat can differentiate into epidermal LCs was markedly reduced with age (P = 0.0057).

298 UF specific desmin and collagen were markedly reduced with EC313 treatment.

299 h a chondrocyte-like gene signature that was markedly reduced with SMC-Klf4 knockout.

300 loading in mice and step aerobics in humans markedly reduced WNT1-inducible signaling pathway protei