ライフサイエンスコーパス: massive

1 stability of functional elements within the massive, ~30kb SARS-CoV-2 RNA genome.

2 is known about the assembly process of this massive ~4 MDa complex.

3 genomic plasticity in Amaranthus palmeri: a massive, ~400-kb extrachromosomal circular DNA (eccDNA)

4 Tricuspid regurgitation was massive (46 mL) (Figs 1-4).

5 In addition, LivKO mice displayed massive accumulation of lipid droplets (LDs) in hepatocy

6 tocopherols (up to approximately 20%) and a massive accumulation of tocotrienols (up to approximatel

7 15 divisions, whereas rDNA circles underwent massive accumulation to >95% of circular DNA.

8 aged cells, and the G1 arrest coincides with massive aggregation of a metastable chaperone-activity r

9 pment, with which could make it suitable for massive allergy screening campaigns to better define sen

10 a show for the first time, to our knowledge, massive alterations of peripheral monocyte subsets in re

11 omechanical actuation, the membrane pushes a massive amount of air and generates high-quality acousti

12 nt advances in biomedical research have made massive amount of transcriptomic data available in publi

13 anges would have allowed the ocean to absorb massive amounts of carbon dioxide, thus limiting the glo

14 e colored plastids that synthesize and store massive amounts of carotenoids.

15 o-O conversion by Goldstein in 1982 required massive amounts of enzyme but enabled proof-of-principle

16 While modern instruments produce massive amounts of tomography data containing extremely

17 ses, including the measles virus, to promote massive amplification within the host, followed by effic

18 Here we perform a massive analysis on near-real-time Italian mobility data

19 e most recent introgression event involved a massive and asymmetrical movement of genes from a distan

20 ) allow for rapid processing and analysis of massive and complex data.

21 otype, while immunological analysis revealed massive and escalating levels of T-cell activation.

22 PeptideAtlas including the PASSEL resource, MassIVE and jPOST), two new resources have joined PX: iP

23 d identified reporter integration sites in a massive and parallel manner.

24 ortions of V1 in four capuchin monkeys after massive and restricted retinal laser lesions.

25 These massive and restricted retinal lesions were intended to

26 tionale but not the implementation of such a massive and risky undertaking, they also proposed an alt

27 r (RV)-to-left ventricular diameter ratio in massive and submassive pulmonary embolism.

28 g coral morphologies: Branching, encrusting, massive, and table.

29 c lethal because postmitotic neurons undergo massive apoptosis in embryos.

30 ening, retinal and callosal activities drive massive apoptosis of GABAergic chandelier cells (ChCs) i

31 ievements in this field, and as a pattern of massive applications, we present here the Jahn-Teller ef

32 fabrication, characterization, and use of a massive array of closed bipolar ultramicroelectrodes (UM

33 A common concern is that such a massive arrival of people-often from a country with a di

34 By integrating massive base-wise and context-dependent annotations in t

35 y dysfunctional fat, transgenic mice display massive beta-cell hyperplasia, reflecting a beneficial m

36 Activity from the super-massive black hole at the Galactic Centre, which is coin

37 and with peripartum complications, including massive bleeding (AUC, 0.80; 95% CI: 0.71, 0.89; P < .00

38 is, except in cases of malignant bleeding or massive bleeding with inability to perform thermal thera

39 ic option that may be considered in cases of massive bleeding with poor visualization, for salvage th

40 delivery, 30 of 126 women (24%) experienced massive blood loss (>2000 mL).

41 o die (54.0% vs 5.5%, P < 0.0001), require a massive blood transfusion (43.5% vs 1.1%, P < 0.0001), o

42 escribed a quarter of a century ago to avoid massive bowel resections in patients with extensive fibr

43 To avoid a massive build-up of plastic in the environment, coordina

44 en the tilted anisotropic Weyl cones and the massive bulk bands.

45 sures, such as vector control, to reduce the massive burden of these diseases.

46 Here, we show that massive calcareous reefs, built slowly by the alga Clath

47 isadvantages: in particular, they can have a massive carbon footprint, they are time-consuming, and t

48 roliferation and differentiation followed by massive cell death in which more than half of all recent

49 Loss of mtd in neurons leads to massive cell loss, early death, and an accumulation of a

50 A massive challenge in ecotoxicology is assessing how the

51 erogeneity of the patient population present massive challenges to the development of early diagnosti

52 Such collapses can be understood as a massive change of network topology, usually accompanied

53 last-to-chloroplast differentiation involves massive changes in plastid ultrastructure, but how these

54 s showing few differences and others showing massive changes of the epigenetic state.

55 CopMich Collaborative - had to respond with massive changes to the organization, staffing and worklo

56 Reunion Island was struck by a massive Chikungunya outbreak in 2005-2006.

57 to postpone DSB repair without accumulating massive chromosomal instability.

58 eir localizations at centromeres and induced massive chromosome alignment defects during mitosis, sug

59 f kinetochore-localized Ipl1 and concomitant massive chromosome missegregation caused by incorrect ch

60 o cleavage by the MUS81 nuclease, leading to massive chromosome shattering.

61 data/master registry trials may also provide massive, clinically relevant datasets that further fuel

62 ntimal founder cells subsequently undergoing massive clonal expansion to form occlusive neointimal le

63 is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in

64 wall biosynthesis by capturing precursors in massive clusters on membranes.

65 Our modelling shows that a massive collapse of terrestrial ecosystems linked to vol

66 rnative as pure ab initio techniques require massive computational resources even for very small prot

67 ination and assembly are used to explore the massive conformational space and generate native-like to

68 nd many more in the region were decimated by massive coral bleaching and mortality.

69 6b(3), which is thought to have an unusually massive core, and recent discoveries such as LTT9779b(4)

70 de, maize lethal necrosis disease has caused massive crop losses in East Africa.

71 me that links cutin monomers, contributes to massive cuticle deposition during the early stages of th

72 It causes massive damage to livestock worldwide.

73 t BM mesenchymal stromal cells (MSC) undergo massive damage to their mitochondrial function after irr

74 ore, key to reanalyzing and integrating this massive data collection are methods that can computation

75 peptide identification due to excellences in massive data processing.

76 Massive data sets are often regarded as a panacea to the

77 e very valuable for the visualization of the massive data sets produced by MSI.

78 To turn massive datasets into predictive quantitative frameworks

79 n important data collection method, yielding massive datasets replete with biological, environmental

80 ndalone software for exploratory analysis of massive datasets.

81 h enables identification of gene programs in massive datasets.

82 n synthetic therapeutic agents have led to a massive decline in ethnomedical therapies.

83 esis predicts an oceanic plateau produced by massive decompression melting during the initiation stag

84 ortex, which appears to be attributable to a massive decrease in the number of deep- and upper-layer

85 uenced 2 d after ischemic stroke, comprising massive decreases of microRNA levels and concomitant inc

86 emely limited carbon loss and, consequently, massive deep subduction of CO(2).

87 P, there was massive immune infiltration and massive desquamation of the luminal epithelial cells.

88 ion, where the conflict has contributed to a massive destruction of health facilities.

89 When the surface massive Dirac band is slightly carrier doped by a gate v

90 andgap GNRs with charge carriers behaving as massive Dirac fermions can be realized when their valenc

91 Massive disk galaxies like the Milky Way are expected to

92 mic is a grave public health crisis, causing massive disruption to daily life.

93 Persistent severe airway obstruction despite massive doses of corticosteroids and maximal pharmacolog

94 tective mechanisms operating in concert with massive down-regulation of gene expression controlling n

95 These were paralleled by a massive dysregulation of blood transcriptome, including

96 ically ambiguous due to the lack of fossils, massive early extinctions, late radiations, limited morp

97 extinction dynamics, similar application of massive eco-evolutionary force in cancer treatment is ty

98 global acceleration in invasions has caused massive ecological damage [1,2].

99 he causal agent of plant diseases that cause massive economic damage.

100 This has spurred a massive effort by the cancer research community to ident

101 ources were localized to higher-metallicity, massive elliptical or star-forming galaxies, suggesting

102 ytes from a sensitive mouse strain overcomes massive embryo developmental arrest characteristic of no

103 ation, mediated by ubiquitin, catalyzed by a massive enzyme machine, called the Anaphase Promoting Co

104 rated into the chromatin and associates with massive epigenetic alterations on the DNA methylation, c

105 , the wet and very cold conditions from this massive eruption on the opposite side of Earth probably

106 rable spots in cities for the celebration of massive events.

107 The paternal genome undergoes a massive exchange of histone with protamine for compactio

108 ng the last 10 million years, leading to the massive expansion by ~65.88% (~970 Mbp) of the whole rub

109 Here, we demonstrate massive expansion of hiPSC-CMs in vitro (i.e., 100- to 2

110 coprotein genes FLO11 and HPF1 We found that massive expansion of intragenic tandem repeats within th

111 uman BLA has undergone a reorganization with massive expansion relative to other amygdala nuclei [5],

112 cted faunas of North and South America was a massive experiment in biological invasion.

113 Nowadays, it is feasible to collect massive features for quantitative representation and pre

114 ible surface areas of nanomaterials to yield massive, finely-controlled, and stable changes in the Se

115 Though rarely witnessed, avulsions can cause massive floods, and over geologic time they create most

116 roach of large-scale mapping studies using a massive forest inventory dataset of 11.8 million trees i

117 aises the questions of the true abundance of massive galaxies and the star-formation-rate density in

118 sive black holes that inhabit the centres of massive galaxies remains unclear(1,2).

119 se galaxies represent the bulk population of massive galaxies that has been missed from previous surv

120 o a few-arcsecond region containing a single massive galaxy at a redshift of 0.66.

121 described by a rich variety of topologically massive gauge theories.

122 We report a massive GC in the Andromeda Galaxy (M31), RBC EXT8, that

123 or for GCs and theoretical expectations that massive GCs could not have formed at such low metallicit

124 c genome reduction has been achieved through massive gene loss and extreme compaction.

125 Due to the low rate of survival and the massive genetic imbalance, little research has been aime

126 Massive genetic studies are currently underway producing

127 Massive genome sequencing has allowed extraction of spec

128 processes underlying the formation of these massive genomes.

129 The COVID-19 pandemic represents a massive global health crisis.

130 reasing attention in recent years due to the massive growth of high-dimensional class-imbalanced data

131 In light of the massive growth of the scientific literature, text mining

132 ns and restore lost functions even following massive (>50%) neuronal loss.

133 This massive (>500 kDa) protein has an N-terminal AAA (ATPase

134 Massive gully land consolidation projects, launched in C

135 r-old woman who had an ischaemic stroke with massive haemorrhagic conversion requiring a decompressiv

136 st, can be effectively diminished to realise massive health and economic benefits and to avert millio

137 pathogen of the COVID-19 pandemic, exerts a massive health and socioeconomic crisis.

138 collapse of the Thermohaline Circulation, a massive Heinrich event, and the onset of the Bipolar See

139 In addition, for life-threatening or massive hemorrhages, reversal of the anticoagulant effec

140 ial necrosis helped identify macrotrabecular-massive hepatocellular carcinoma subtype with high speci

141 thy in severe YF has long been attributed to massive hepatocyte infection and destruction that result

142 osure of inferior vena cava in patients with massive hepatomegaly related to PLD: the exposure left l

143 enabled us to integrate and cross-evaluate a massive, heterogeneous dataset based on measurements rep

144 They form massive heterotetrameric complexes endowed with unique a

145 tegy might offer a potential alternative for massive high-throughput screening for NSCLC in clinical

146 ng suggests that radiative forcing from this massive, high-latitude eruption led to pronounced change

147 uncovered a molecular interplay that enables massive hiPSC-CM expansion for large-scale drug screenin

148 nosis of cancer, manually counting nuclei on massive histopathological images is tedious and the coun

149 broiler chickens in Bangladesh suggesting a massive horizontal spread of mcr-1 rather than by clonal

150 entrated around Delhi, likely in response to massive human food-subsidies.

151 aying an autosomal recessive form of NS with massive hypertrophic cardiomyopathy as clinically the mo

152 Despite massive hypertrophy on the myofiber level, we report no

153 ed optics should capture, store, and process massive image information independently.

154 G became atrophic, and, in the VP, there was massive immune infiltration and massive desquamation of

155 h microbes is a ubiquitous phenomenon with a massive impact on all living organisms, shaping the worl

156 tic tape worms and blood flukes that exert a massive impact on human health.

157 duction of a periderm cylinder, particularly massive in the proximal portion of the trunk and taperin

158 ial distancing is eliminated there will be a massive increase in the cases of COVID-19.

159 , the water-to-land transition resulted in a massive increase in visual range.

160 urine hepatocytes (Shp (Hep-/-)) resulted in massive infiltration of macrophages and CD4(+) T cells i

161 atomical distributions of SARS-CoV-2 RNA and massive infiltration of T cells and macrophages.

162 ightly reduced cyst burden, it resulted in a massive infiltration of the cystic kidneys by macrophage

163 BDL induced massive inflammation (increased leukocyte infiltration,

164 Fasting causes a massive influx of adipose-derived fatty acids into the l

165 evidence-based policies that could influence massive investments in the built urban environment in LM

166 he macroscopic and microscopic findings of a massive iron deposition in the liver, heart, lungs, sple

167 GNPS-MassIVE is a public data repository for untargeted MS(2)

168 om numerous knowledge bases and encoded in a massive "Knowledge Network." KnowEnG adheres to "FAIR" p

169 thetic biology are relying on and developing massive libraries of plasmids as vectors for directed ev

170 taurus (bull) and find it to be dominated by massive, lineage-specific amplification of testis-expres

171 virus (HIV) infection is characterized by a massive loss of CD4 T cells in the gastrointestinal trac

172 type C disease, a disorder characterized by massive lysosomal accumulation of cholesterol and glycos

173 urce to best share, annotate and analyze the massive m7G data generated recently are sorely needed.

174 We discovered massive macromolecular clusters on the luminal face of E

175 hen the BTO undergoes a crystal transition a massive magnetization and coercivity change is triggered

176 er and Upper Kellwasser events, during which massive marine biodiversity losses occurred.

177 rey Hypothesis uses this excursion to invoke massive marine organic carbon burial and draw-down of at

178 , high-throughput chemical identification of massive metabolite spaces, and we expect it to revolutio

179 (MGs) are two material classes based on the massive mixing of multiple-principal elements.

180 (M) Syrian refugees in Turkey inferred from massive mobile-phone data to verify this concern.

181 otic and abiotic stressors causing recurrent massive mortalities in other bivalves.

182 chytrium salamandrivorans [Bsal]) is causing massive mortality of salamanders in Europe.

183 ound The recently described "macrotrabecular-massive" (MTM) histologic subtype of hepatocellular carc

184 One such structure is the massive, mucin-based, soft, flexible laminated layer (LL

185 One hundred fifty patients with massive (n=31) or submassive (n=119) pulmonary embolism

186 Liver failure leads to the massive necrosis of hepatocytes, releasing large amounts

187 the mouse brain and spinal cord resulting in massive neurodegeneration of infected regions.

188 A massive number of biological entities, such as genes and

189 Under a massive number of conditions (2000+), we consistently fo

190 sion of statistical power resulting from the massive number of statistical tests required to detect s

191 ffer across individuals in a correspondingly massive number of ways, or whether most differences take

192 focused streams of cells effectively deplete massive numbers of magnetically labeled leukocytes withi

193 au, the oil capital of the country where two massive oil fields are located.

194 We found massive oncogene-induced changes to the glycoproteome an

195 ltiple lenses for recognizing an object from massive optical inputs.

196 movement of saliva within the salivarium and massive outpouring of saliva.

197 resistance escalation was associated with a massive overexpression of the duplicated cytochrome P450

198 forward strike" is sensorially mediated by a massive pair of hypersensitive, night-vision eyes [5-7].

199 of 60 TNBC samples were RNA-sequenced using massive parallel sequencing.

200 auses of rare and undiagnosed diseases using massive-parallel sequencing often require complementary

201 This is how massive parallelism is achieved in that there are N (2)

202 umed to be in the form of weakly interacting massive particles of mass approximately 100 gigaelectron

203 (0.5)MA(0.5)Sn(0.5)Pb(0.5)I(3) structure has massive Pb/Sn vacancies and much higher chemical stabili

204 MO were compared, between 2005 and 2019, for massive PE (MPE) versus high-risk submassive PE (SMPE).

205 t ventricular compromise, whereas high-risk (massive) PE comprises those who have experienced hemodyn

206 retinal barrier cells are known to exhibit a massive phenotypic change during experimental autoimmune

207 f eukaryotic phytoplankton, and the onset of massive phosphorite deposition.

208 t of ice giant planets(14) demonstrated that massive planets might also find their way into tight orb

209 ight sided pleural thickening coupled with a massive pleural effusion.

210 hology of silicon particles is modified from massive polygonal and plate-like to a mixture of fine fl

211 e migration routes and breeding areas of the massive population of migratory Black-eared kites winter

212 tiagent models for the efficient analysis of massive populations of interacting agents.

213 humilis, Acropora muricata, Pocillopora and massive Porites) were surveyed in February 2016 and Octo

214 Moreover, Dcc-deficient retinas displayed a massive postnatal loss of retinal ganglion cells and a l

215 ing the saving rate of Shandong has the most massive potential for global CO(2) reductions, while tha

216 n the global carbon cycle like a sponge: its massive production contributes significantly to present-

217 ere more susceptible to LPS challenge due to massive production of cytokines.

218 his powerful MPC technique allows us to gain massive productivity increases (shorter cycle time and h

219 al, but not into the auditory AI, revealed a massive projection to tectal layer 13 and other tectal r

220 ance of the large-scale AFP by incorporating massive protein-protein network information.

221 ell stress and undergo apoptosis, leading to massive pruning of nascent blood vessels.

222 Both allergens induced massive pulmonary apoptosis and also significantly incre

223 Eligible patients had submassive or massive pulmonary embolism and an RV/LV diameter ratio >

224 eter-directed thrombolysis for submassive or massive pulmonary embolism.

225 marine PTME are best explained by a sudden, massive pulse of terrestrial biomass oxidation, while vo

226 MassIVE.quant is a repository infrastructure and data re

227 A branch structure enables MassIVE.quant to systematically store raw experimental d

228 amin D and calcium supplementation developed massive Randall's plaque when compared with control Abcc

229 Here, in a massive reanalysis of CRISPR tiling data using the most

230 Remarkably, loss of FoxA caused rapid and massive reduction in the expression of critical liver ge

231 et PMN-dependent tumor control, leading to a massive reduction in tumor burden.

232 ther incongruent or congruent) resulted in a massive reduction of post-saccadic neural responses.

233 This is explained by the massive reduction of the mass transfer resistance in the

234 nd refinement of SCS technologies has led to massive reductions in costs, increased cell throughput,

235 ogical time scales, lead to the formation of massive reefs in shallow tropical and subtropical seas.

236 shifts in optical side scatter signals and a massive release of detached coccoliths in a subpopulatio

237 A massive release of platelet-derived MVs occurs during HI

238 Concomitantly, a massive relocation of organelles attached to MTs is obse

239 Enterovirus infection induces the massive remodeling of intracellular membranes and the de

240 Stress causes a massive reorganization of the transcriptional program.

241 In light of this, massive research efforts have been devoted to the design

242 Mycobacteriophages thus present a massive reservoir of genes for identifying mycobacterial

243 The existence of such a massive, rotationally supported, cold disk galaxy when t

244 e Small Magellanic Cloud (SMC), the two most massive satellite galaxies of the Milky Way(1-4).

245 ve we experienced social isolation on such a massive scale as we have in response to coronavirus dise

246 ountries, the use of diagnostic testing on a massive scale has been a cornerstone of successful conta

247 o-field stability in arbitrary patterns on a massive scale in exchange-biased magnetic multilayers is

248 h worldwide, prompting research efforts on a massive scale in search of novel antibiotics to fill an

249 The use of group testing on a massive scale to monitor infection rates closely and con

250 long-term funding of free well testing on a massive scale with piped water or groundwater treatment

251 ree key characteristics (rapid construction, massive scale, and low cost) and five essential function

252 Over the past decade, there has been a massive scale-up of primary and secondary prevention ser

253 etraploid and 3,903 crop wild relatives in a massive-scale genotyping and diversity analysis.

254 s the authors' experience in operating these massive-scale isolation facilities while prioritizing sa

255 loping similar solutions for the analysis of massive scientific data.

256 PWS and AS, however, the need of WB makes a massive screening difficult in newborns due to economic

257 of repeat sequences that are associated with massive segmental gene duplications, likely facilitating

258 Massive sequencing provided the essential framework for

259 'Hot Jupiters' (massive, short-period exoplanets) predominantly exist in

260 s a free cobenefit, which is vital given the massive shortfall in funding for biodiversity conservati

261 However, the massive size of short reads makes de novo transcripts as

262 bitively difficult, primarily owing to their massive size.

263 The global soil carbon (C) pool is massive, so relatively small changes in soil organic car

264 ral titers in combination with attendance at massive social gatherings or extensive contact among per

265 The massive socioeconomic impacts engendered by extreme floo

266 ion in a nearby (redshift 0.0337 +/- 0.0002) massive spiral galaxy, whose properties and proximity di

267 Traumatic maculopathy and massive SRH after closed-globe injury often cause poor v

268 Massive SRSF7 binding to these sites and its oligomeriza

269 n, point to the core-collapse explosion of a massive star, and probe supernova nucleosynthesis.

270 (1,2)), a cluster of young, massive stars (the S stars(3)) and various gaseous featu

271 of 2.6 My that is predominantly produced in massive stars and ejected in supernova explosions.

272 Nuclides synthesized in massive stars are ejected into space via stellar winds a

273 It is important to determine if massive stars form via disc accretion, like their low-ma

274 tions or external photoevaporation by nearby massive stars(9).

275 inary interactions dominate the evolution of massive stars, but their role is less clear for low- and

276 pernovae are likely due to core collapses of massive stars; these are concentrated in the thin Galact

277 bstantial fluxes are expected to increase as massive stocks of frozen organic matter in permafrost ar

278 The inflamed subtype (11%) presented a massive T lymphocyte infiltration, an activation of infl

279 Applying massive temporal feature extraction to regional haemodyn

280 ent of the local environment for haloes less massive than those of typical galaxies.

281 mFS but none of the eyes with iERM-FS showed massive thinning of the ILM with prominent retinal undul

282 topically inoculated in the back skin showed massive thrombus formation in the lungs, but the cancer-

283 Our analyses show that massive-throughput assays of fully random DNA can provid

284 Proximity RNA-seq is based on massive-throughput RNA barcoding of subnuclear particles

285 nset erythroderma and gut inflammation, with massive tissue infiltration of oligoclonal activated T c

286 e growth defects, transcriptomic changes and massive, transcription-related redistribution of elongat

287 Whether it entailed a single massive transfer event or a gradual stream of transfers

288 Massive transfusion protocols are the mainstay of treatm

289 the skeletal intracrystalline amino acids of massive, tropical Porites spp. corals cultured over diff

290 Here, we assessed alpha-band modulation with massive univariate deconvolution, an analysis approach t

291 The massive usage of antibiotics during farm animal producti

292 ion of the basement membrane triggers rapid, massive vascular retraction without loss of barrier func

293 Galaxy clusters are the most massive virialized structures in the Universe and are fo

294 high-efficiency, and flexible generation of massive vortex beams with structured state-of-polarizati

295 ts an ensemble learning scheme that utilizes massive weak learners for an accurate similarity search.

296 system containing PSR J1141-6545 includes a massive white dwarf (WD) companion that formed before th

297 Massive wildlife losses over the past 50 y have brought

298 e as Jupiter and is no more than 14 times as massive (with 95 per cent confidence).

299 f FRB 121102, as it is a thousand times more massive, with a specific star-formation rate (the star-f

300 single-cell RNA-Seq (scRNA-Seq) data, where massive zero and low expression values are observed.