ライフサイエンスコーパス: massively-parallel sequencing

1 es of specific genomic loci (40 cases) using massively parallel sequencing.

2 short hairpin RNA (shRNA) library screen and massively parallel sequencing.

3 n, let alone more complex, disorders through massively parallel sequencing.

4 ghput commensurate with the current scale of massively parallel sequencing.

5 is modified with unique flanking tags before massively parallel sequencing.

6 that have become feasible with the advent of massively parallel sequencing.

7 ary using affinity purification coupled with massively parallel sequencing.

8 latforms have been developed with the use of massively parallel sequencing.

9 iopathy candidate exome capture' followed by massively parallel sequencing.

10 e sensitivity of detecting such mutations by massively parallel sequencing.

11 cted the exomes of ten unrelated probands to massively parallel sequencing.

12 five-microorganism metatranscriptomes using massively parallel sequencing.

13 es by coupling proximity-based ligation with massively parallel sequencing.

14 re required to realize the full potential of massively parallel sequencing.

15 extended the TimEX method genome-wide using massively parallel sequencing.

16 hIP-seq) data obtained by coupling ChIP with massively parallel sequencing.

17 dard library preparation method suitable for massively parallel sequencing.

18 torial barcodes that enable multiplexing and massively parallel sequencing.

19 high throughput using affinity selection and massively parallel sequencing.

20 deletion in the cDNA that is detected using massively parallel sequencing.

21 RNA editing and global gene expression using massively parallel sequencing.

22 gestion of nuclei withMPE-Fe(II) followed by massively parallel sequencing.

23 and then counting the resulting mutations by massively parallel sequencing.

24 rming growth factor beta 1 (TGFbeta1), using massively parallel sequencing.

25 blockade were characterized with the use of massively parallel sequencing.

26 otides during cDNA synthesis, as measured by massively parallel sequencing.

27 say (OLA), an economical and simple test, to massively parallel sequencing.

28 ols were pooled respectively and profiled by massively parallel sequencing.

29 abled a complex mutant pool to be tracked by massively parallel sequencing.

30 c aHUS using targeted genomic enrichment and massively parallel sequencing.

31 BROCA Agilent cancer risk panel followed by massively parallel sequencing.

32 tify promising detection strategies based on massively-parallel sequencing.

33 Using a GWAS approach and target-enriched massively-parallel sequencing, a strongly associated non

34 Purpose Massively parallel sequencing allows simultaneous testin

35 In contrast, massively parallel sequencing allows such testing for ma

36 d challenges arising from the application of massively parallel sequencing-also known as next-generat

37 ls, and by chromatin immunoprecipitation and massively parallel sequencing analysis of gammaH2AX, we

38 ve chromatin immunoprecipitation followed by massively parallel sequencing analysis of H3K9me2 distri

39 f neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis.

40 map temporally ordered replicating DNA using massively parallel sequencing and applied it to study re

41 We undertook sequence capture, massively parallel sequencing and computational alignmen

42 of chromatin immunoprecipitation coupled to massively parallel sequencing and gene expression data.

43 assessment of beta-MHC variant abundance by massively parallel sequencing and hiPSC-derived cardiomy

44 ring high performance liquid chromatography, massively parallel sequencing and multiplex-ligation-dep

45 high throughput molecular techniques such as massively parallel sequencing and phylogenetic microarra

46 Massively parallel sequencing and related methods reveal

47 Already, the combination of massively parallel sequencing and selective capture appr

48 Massively parallel sequencing and splicing-sensitive jun

49 juvenile crabs and oysters from the UK using massively parallel sequencing and targeted primer approa

50 tion are identified in single RNA strands by massively parallel sequencing and then analyzed for corr

51 the past 15 years, technology, particularly massively parallel sequencing, and bioinformatics advanc

52 cancers using gene copy number profiling and massively parallel sequencing, and identified potential

53 enhancer-associated protein p300 followed by massively parallel sequencing, and map several thousand

54 , chromatin immunoprecipitation coupled with massively parallel sequencing, and RNA-Seq were assessed

55 sm mapping, microsatellite linkage, targeted massively parallel sequencing, and Sanger sequencing.

56 to genetic testing (n = 1,076), by targeted massively parallel sequencing, and we accessed Genomics

57 roductive and latent infection, we applied a massively parallel sequencing approach.

58 factor in the vastly improved efficiency of massively parallel sequencing approaches.

59 Technologies for massively parallel sequencing are revolutionizing microb

60 generates products suitable for analysis by massively parallel sequencing as well as microarray hybr

61 (351) of infant and young SD decedents using massively parallel sequencing at <$600 per sample.

62 Similarly, massively parallel sequencing-based analyses have identi

63 mented includes targeted genomic enrichment, massively parallel sequencing, bioinformatic analysis, a

64 Massively parallel sequencing by oligonucleotide ligatio

65 Using massively parallel sequencing by synthesis methods, we h

66 We performed massively parallel sequencing by using cohorts of geneti

67 sequencing of mtDNA genomes with the use of massively parallel sequencing-by-synthesis approaches.

68 A massively parallel sequencing-by-synthesis method (454 s

69 e used on as little as 10 ng of DNA and that massively parallel sequencing can be used as an alternat

70 Here, we used ChIP coupled to massively parallel sequencing (ChIP-seq) and gene expres

71 Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) coupled to time

72 y chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) has recently be

73 ChIP followed by massively parallel sequencing (ChIP-Seq) is a powerful,

74 on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that pr

75 m chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-seq) of multiple tra

76 , we used chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) on CRX to ident

77 chromatin immunoprecipitation combined with massively parallel sequencing (ChIP-seq) to identify >75

78 e chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) to identify bet

79 ly, chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq) to identify gen

80 , we used chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) to identify Hox

81 ed chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 1 d after 7 da

82 ng chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 312 chromosoma

83 matin immunoprecipitation (ChIP) paired with massively parallel sequencing (ChIP-seq), gene expressio

84 tin immunoprecipitation (ChIP) combined with massively parallel sequencing (ChIP-Seq), we show that F

85 by chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq).

86 ir-end tag sequencing (ChIP-PET), to current massively parallel sequencing (ChIP-seq).

87 ctivating histone modifications coupled with massively parallel sequencing (ChIP-seq).

88 Whole-exome capture and massively parallel sequencing combined with homozygosity

89 d chromatin immunoprecipitation coupled with massively parallel sequencing confirmed PU.1 binding in

90 With the advent of massively parallel sequencing, considerable work has gon

91 Recently, massively parallel sequencing coupled with ChIP experime

92 isplays clonal DNA methylation patterns from massively parallel sequencing data aligned using Bismark

93 gene expression, chromosomal copy number and massively parallel sequencing data from 947 human cancer

94 Finding somatic mutations from massively parallel sequencing data is becoming a standar

95 RtN!) was developed to categorize reads from massively parallel sequencing data not based on the expe

96 lable to efficiently detect such variants in massively parallel sequencing data.

97 this approach in binding site inference from massively parallel sequencing data.

98 on in sequence markedly under-represented in massively parallel sequencing data: the insertion of a s

99 DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprint

100 ies, 2) DNaseI hypersensitivity coupled with massively parallel sequencing (DNase-seq), and 3) chroma

101 xplores the current state of genomics in the massively parallel sequencing era.

102 Massively parallel sequencing facilitates strain-to-refe

103 Four studies have shown the utility of massively parallel sequencing for comprehensive genetic

104 ame feasible with the recent availability of massively parallel sequencing for detection of all codin

105 ssment and Counseling (Family CARE Project), Massively Parallel Sequencing for Familial Colon Cancer

106 Our results reveal the value of massively parallel sequencing for identification of nove

107 ng chromatin immunoprecipitation followed by massively parallel sequencing, genome-wide maps of candi

108 With the emergence of massively parallel sequencing, genomewide expression dat

109 As massively parallel sequencing has emerged as a leading t

110 ns of individual genomic cleavage events via massively parallel sequencing has enabled in vivo DNase

111 Using massively parallel sequencing has enabled investigators

112 Massively parallel sequencing has enabled the rapid, sys

113 Recently, massively parallel sequencing has identified recurrent m

114 Massively parallel sequencing has not previously been le

115 Massively parallel sequencing has permitted an unprecede

116 Massively parallel sequencing has proven revolutionary,

117 l strategies including the new technology of massively parallel sequencing has provided insight into

118 Massively parallel sequencing has revealed many de novo

119 Short-read massively parallel sequencing has revolutionized our abi

120 The sensitivity of massively-parallel sequencing has confirmed that most ca

121 Chemical probing methods coupled with massively parallel sequencing have revolutionized the RN

122 Novel methods, such as massively parallel sequencing, have begun to describe th

123 itro DNA affinity purification combined with massively parallel sequencing (IDAP-Seq) to identify gen

124 Massively parallel sequencing identified 12,732-19,704 H

125 quences by chromatin immunoprecipitation and massively parallel sequencing identified 2294 peaks.

126 We performed massively parallel sequencing in a blinded fashion to de

127 brain development and emphasize the power of massively parallel sequencing in a challenging context o

128 with solution-based whole-exome capture and massively parallel sequencing in a large Caucasian pedig

129 Anti-Brd3 ChIP followed by massively parallel sequencing in GATA1-deficient erythro

130 d to 7.4-fold redundancy in two months using massively parallel sequencing in picolitre-size reaction

131 sequenced mtDNA using both direct Sanger and Massively Parallel Sequencing in several tissues of elev

132 Massively parallel sequencing includes many liquid handl

133 of KERV long terminal repeat sequences using massively parallel sequencing indicates that the recent

134 Clinical samples were sequenced on a massively parallel sequencing instrument, and anaplastic

135 olecular barcoding and can be applied to any massively parallel sequencing instrument.

136 Although massively parallel sequencing instruments are in princip

137 Massively parallel sequencing instruments enable rapid a

138 an substantially increase the sensitivity of massively parallel sequencing instruments for this purpo

139 Variant interpretation in the era of massively parallel sequencing is challenging.

140 Massively parallel sequencing is increasingly used to in

141 Massively parallel sequencing is performed on libraries

142 We conclude that massively parallel sequencing is useful to characterize

143 cipitation (ChIP) with ultra high-throughput massively parallel sequencing, is increasingly being use

144 es chromatin immunoprecipitation (ChIP) with massively parallel sequencing, is rapidly replacing ChIP

145 cost and throughput advances associated with massively parallel sequencing, it remains challenging to

146 nces in sequencing technologies suggest that massively parallel sequencing may provide a feasible alt

147 rotein 2 (MBD) enrichment of DNA followed by massively parallel sequencing (MBD-seq) was used to map

148 In this study, we used exon capture and massively parallel sequencing methods to analyze the mut

149 Using massively parallel sequencing methods, we have identifie

150 stinct populations sequenced with orthogonal massively parallel sequencing methods.

151 New 'massively parallel' sequencing methods are greatly incre

152 Here we propose to use massively parallel sequencing (MPS) for sensitive detect

153 ad mutation(s) in the same gene but targeted massively parallel sequencing (MPS) of 1,034 genes encod

154 e characterization of TSC mosaicism by using massively parallel sequencing (MPS) of 330 TSC samples f

155 Accurate massively parallel sequencing (MPS) of genetic variants

156 We used massively parallel sequencing (MPS) of the 16S rRNA gene

157 Massively parallel sequencing (MPS) technologies includi

158 We used degenerate PCR assays and massively parallel sequencing (MPS) to identify a novel

159 Massively parallel sequencing (MPS) was performed with 2

160 Massively Parallel Sequencing (MPS) was used to characte

161 alysis and interpretation of assays based on massively-parallel sequencing (MPS) are both individuall

162 for the presence of somatic mutations using massively parallel sequencing (next-generation sequencin

163 a proof of principle, we performed targeted, massively parallel sequencing of 138 cancer genes in a t

164 Here we report the massively parallel sequencing of 38 tumour genomes and t

165 Genomic analysis by massively parallel sequencing of 504 cancer genes was pe

166 h chronic lymphocytic leukemia and performed massively parallel sequencing of 88 whole exomes and who

167 capillary sequencing of candidate genes, and massively parallel sequencing of all coding exons.

168 We employed massively parallel sequencing of all X-chromosome exons

169 methylation results from targeted amplicon, massively parallel sequencing of bisulfite converted DNA

170 Massively parallel sequencing of captured subgenomic lib

171 Using paired-end massively parallel sequencing of cDNA (RNA-seq) together

172 Massively parallel sequencing of cDNA has enabled deep a

173 ons in solid cancers can be characterized by massively parallel sequencing of circulating cell-free t

174 Massively parallel sequencing of CSF ctDNA more comprehe

175 Massively parallel sequencing of DNA by pyrosequencing t

176 rty-nine CMT genes were analyzed by targeted massively parallel sequencing of genomic DNA from patien

177 characterized MdBV replication and performed massively parallel sequencing of M. demolitor ovary tran

178 The use of massively parallel sequencing of maternal cfDNA for non-

179 noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-fr

180 Massively parallel sequencing of millions of < 30-nt RNA

181 oning analysis of Arabidopsis thaliana using massively parallel sequencing of mononucleosomes.

182 rial genome variation and heteroplasmy using massively parallel sequencing of mtDNA in a cohort of pa

183 We performed massively parallel sequencing of paired tumor/normal sam

184 Herein, massively parallel sequencing of Podophyllum hexandrum a

185 Patients who underwent targeted massively parallel sequencing of primary ECs between 201

186 l relevance of MEK dependency in melanoma by massively parallel sequencing of resistant clones genera

187 Recently, methods for massively parallel sequencing of ribosome-bound fragment

188 Massively parallel sequencing of Sin3A- and Sin3B-bound

189 Massively parallel sequencing of targeted regions, exome

190 Massively parallel sequencing of the entire 2.2-Mb inter

191 Here we report on the targeted capture and massively parallel sequencing of the exomes of 12 humans

192 with reduced genomic library preparation and massively parallel sequencing of the same samples using

193 homozygosity mapping, Sanger sequencing, and massively parallel sequencing of the whole exome.

194 Massively parallel sequencing of this representation all

195 ines high-density transposon mutagenesis and massively parallel sequencing of transposon/chromosome j

196 disorders can be rapidly discovered through massively parallel sequencing of whole genomes or exomes

197 e, confirm linkage to Xp11.23-q13.3, perform massively parallel sequencing of X chromosome exons, fil

198 Massively-parallel sequencing of non-coding hotspots was

199 ric CN-AML, we performed whole-transcriptome massively parallel sequencing on blasts from 7 CN-AML pe

200 ing on the flow cells of currently available massively parallel sequencing platforms as an efficient

201 Recent progress in massively parallel sequencing platforms has enabled geno

202 Studying tumor SCNAs using massively parallel sequencing provides unprecedented res

203 rization of sequencing chemistries, enabling massively parallel sequencing reactions to be carried ou

204 Targeting genomic loci by massively parallel sequencing requires new methods to en

205 Chromatin immunoprecipitation coupled with massively parallel sequencing reveals that macrophage YA

206 mation was recovered perfectly from a single massively parallel sequencing run.

207 Massively parallel sequencing studies have led to the id

208 Recent evidence from proteomics and deep massively parallel sequencing studies have revealed that

209 In this study, a massively parallel sequencing technique that is based on

210 The development of massively parallel sequencing techniques has presented t

211 Massively parallel sequencing technologies are useful fo

212 We show that new high-throughput, massively parallel sequencing technologies can completel

213 Massively parallel sequencing technologies can overcome

214 The advent of massively parallel sequencing technologies has allowed t

215 precipitation (ChIP) with recently developed massively parallel sequencing technologies has enabled g

216 cost due to the emergence and improvement of massively parallel sequencing technologies has resulted

217 Use of chromosomal microarray and massively parallel sequencing technologies has revealed

218 ver the past decade, the decreasing costs of massively parallel sequencing technologies have facilita

219 Recent studies using massively parallel sequencing technologies have implicat

220 In recent years, advances in massively parallel sequencing technologies have led to r

221 Massively parallel sequencing technologies have made the

222 The massively parallel sequencing technologies have recently

223 Massively parallel sequencing technologies hold incredib

224 ly from personal genomes sequenced using the massively parallel sequencing technologies is becoming a

225 Massively parallel sequencing technologies provide great

226 Massively parallel sequencing technologies provide sensi

227 ess the feasibility of target-enrichment and massively parallel sequencing technologies to interrogat

228 enomics has grown rapidly with the advent of massively parallel sequencing technologies, allowing for

229 The development of massively parallel sequencing technologies, coupled with

230 With the wide availability of massively parallel sequencing technologies, genetic mapp

231 he advent and application of next-generation massively parallel sequencing technologies, one can rapi

232 ness, both of which have been enabled by new massively parallel sequencing technologies.

233 hment), a method for aptamer discovery, with massively parallel sequencing technologies.

234 being discovered at an increasing rate using massively parallel sequencing technologies.

235 quencing is performed with 'next-generation' massively parallel sequencing technologies: in June 2008

236 Massively parallel sequencing technology and the associa

237 The massively parallel sequencing technology can be used by

238 Massively parallel sequencing technology coupled with sa

239 New massively parallel sequencing technology enables, throug

240 Massively parallel sequencing technology has made signif

241 The emergence of massively parallel sequencing technology has revolutioni

242 Recent advances in massively parallel sequencing technology have created ne

243 We used massively parallel sequencing technology to decode the g

244 seq (chromatin immunoprecipitation following massively parallel sequencing technology).

245 Using massively parallel sequencing technology, we sequenced a

246 d it would be highly desirable to apply such massively parallel sequencing to bisulfite-converted who

247 sampled the esophagus could be combined with massively parallel sequencing to characterize aneuploidy

248 erial small-subunit (16S) rRNA combined with massively parallel sequencing to determine the community

249 ed a targeted captured technique followed by massively parallel sequencing to determine the exact bre

250 orm whole-exome analyses of 22 tumours using massively parallel sequencing to determine the mutationa

251 ntly, a genome-wide study was reported using massively parallel sequencing to directly compare in viv

252 We used massively parallel sequencing to examine tumor samples c

253 Here, we used massively parallel sequencing to explore samples from a

254 In this study, we used Illumina-based massively parallel sequencing to gain new insight into t

255 We used massively parallel sequencing to generate sequence reads

256 We performed massively parallel sequencing to identify gastrointestin

257 Massively parallel sequencing to identify rare variants

258 Here, we have used genome-wide massively parallel sequencing to map replication initiat

259 a library of barcoded lentiviruses and used massively parallel sequencing to quantify the clonal dis

260 sociated with chemotherapy exposure, we used massively parallel sequencing to quantitate mutations in

261 We used exome capture coupled with massively parallel sequencing to search for metastasis-r

262 Therefore, we employed massively parallel sequencing to search for somatic mosa

263 ChIP-seq (chromatin immunoprecipitation with massively parallel sequencing) to analyze the genome-wid

264 dologies (multiplex target amplification and massively parallel sequencing) to historical specimens f

265 itro DNA affinity purification combined with massively parallel sequencing, to identify B. subtilis c

266 In this study, we describe a massively parallel sequencing tool termed Mutation And D

267 -phenotype information, variant abundance by massively parallel sequencing (VAMP-seq) is leveraged to

268 uman cell line by using variant abundance by massively parallel sequencing (VAMP-seq).

269 Here, using massively parallel sequencing, we characterize expressed

270 immunoprecipitation experiments coupled with massively parallel sequencing, we found that genome-wide

271 Combining whole-genome shRNA screening with massively parallel sequencing, we have profiled the impa

272 hod that combines end-sequence profiling and massively parallel sequencing, we obtained a sequence-le

273 or the inclusion of somatic mutation data by massively parallel sequencing, we propose a framework fo

274 me can be detected by microarray methods and massively parallel sequencing, which identify copy-numbe

275 Here we combine the throughput of massively parallel sequencing with the contiguity inform