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1 ed to receive either 300 mg clopidogrel or a matching placebo administered a minimum of 3 h and a max
3 parib (as capsules; 400 mg twice a day) or a matching placebo by an interactive voice response system
9 00 mg, or 150 and 600 mg, respectively, or a matching placebo for a period of 40 weeks, and then to u
10 ion > or = 12 hours before angiography) or a matching placebo infusion with provisional use of eptifi
12 folic acid, vitamin B6, and vitamin B12 or a matching placebo, and were treated for 7.3 years from Ap
20 pressant therapy or a mood stabilizer plus a matching placebo, under conditions generalizable to rout
24 ects of 40 mEq K/d as KCl supplements with a matching placebo, taken for 3 mo, on measures of potassi
25 5), 40 mg/kg praziquantel and an albendazole-matching placebo (n=626), or an albendazole-matching pla
26 -matching placebo (n=626), or an albendazole-matching placebo and praziquantel-matching placebo (n=62
28 2 received oral valacyclovir, acyclovir, and matching placebo in random order for 7-week periods.
30 mycin 125 mg four times a day with cadazolid-matching placebo suspension twice daily for 10 days, wit
34 nous nivolumab every 2 weeks plus ipilimumab-matching placebo during weeks 1-12), or double-matching
40 ne, 100 mg orally twice daily (n = 1215), or matching placebo (n = 1210) in addition to standard care
44 eceived either MC-1, 250 mg/d (n = 1519), or matching placebo (n = 1504) immediately before and for 3
45 to twice daily aciclovir 400 mg (n=1637) or matching placebo (n=1640) for 12-18 months, and were see
46 twice-daily losmapimod (7.5 mg; n = 1738) or matching placebo (n = 1765) on a background of guideline
47 intramuscular injections of 250 mg of 17P or matching placebo, starting at 16 to 20 weeks of gestatio
48 reatment with daily oral lithium (n = 18) or matching placebo (n = 16) at the primary outcome showed
50 ining 100 mg of total isoflavones (n=193) or matching placebo (n=193) in 2 divided doses administered
52 atorvastatin the morning after (n = 206) or matching placebo (n = 210), and resumed taking the previ
53 5 mg of spironolactone once daily (n=213) or matching placebo (n=209) with 12 months of follow-up.
54 one titrated from 15 mg to 45 mg (n=2605) or matching placebo (n=2633), to be taken in addition to th
57 on day 1 and 2 mg orally on days 2 to 3) or matching placebo, granisetron (2 mg orally on days 1 to
59 hromycin (12 mg/kg/d for 5 days; n = 307) or matching placebo (n = 300), started early during each pr
61 ed-release 1000 mg twice daily, n = 3279) or matching placebo (n = 3281), and followed up for a media
65 ients to receive losartan, 100 mg (n=77), or matching placebo (n=76) within 3 months of transplantati
66 (n=79), 105 mg (n=79), or 140 mg (n=78), or matching placebo (n=78) every 2 weeks; or AMG 145 280 mg
69 dministered ramipril 10 mg per day (n=82) or matching placebo (n=83) for 24 weeks in a randomized, do
72 e of 1 mg, 2.5 mg, 5 mg, or 10 mg TA-8995 or matching placebo; 10 mg TA-8995 plus 20 mg atorvastatin;
75 ocated clopidogrel 75 mg daily (n=22,961) or matching placebo (n=22,891) in addition to aspirin 162 m
76 subjects received 4 rounds of albendazole or matching placebo with 3-month intervals, for 3 consecuti
79 atients received 80 mg atorvastatin (ATV) or matching placebo for a 12-week treatment period with a m
81 omized to treatment with either cangrelor or matching placebo (bolus followed by 2-hour infusion).
83 ere randomly assigned to receive cytisine or matching placebo for 25 days; participants in both group
88 misation to rifampicin 300 mg twice daily or matching placebo (50 mg riboflavin capsules), stratified
89 rtan at a target dose of 32 mg once daily or matching placebo and followed up for a median of 38 mont
90 ere randomized to 40 mg simvastatin daily or matching placebo for 5 years, which, on average, reduced
94 either 500 mg of levofloxacin once daily or matching placebo for seven days during the expected neut
95 omly assigned to atorvastatin 10 mg daily or matching placebo in a randomised double-blind placebo-co
96 ther nintedanib 200 mg orally twice daily or matching placebo on days 2-21, every 3 weeks until unacc
103 an (n=3803, titrated to 32 mg once daily) or matching placebo (n=3796), and followed up for at least
104 sease to receive vorapaxar (2.5 mg daily) or matching placebo and followed them for a median of 30 mo
105 nuous oral sorafenib (400 mg twice-daily) or matching placebo combined with TACE using drug-eluting b
108 ns of atopaxar (50, 100, or 200 mg daily) or matching placebo for 24 weeks and followed up for an add
110 tide (dose escalated to 14 mg once daily) or matching placebo for 26 weeks, in addition to background
116 00 mg in two 150 mg tablets, twice daily) or matching placebo tablets using an interactive voice and
117 mized to receive rimonabant (20 mg daily) or matching placebo, and underwent coronary intravascular u
123 d either 150 mg of anacetrapib once a day or matching placebo with a meal for 10 days in each crossov
129 2 mg per kilogram of body weight per day) or matching placebo for one year and were followed for an a
131 d to daily sorafenib (400 mg twice a day) or matching placebo plus gemcitabine (1,250 mg/m(2) per day
132 receive oral buparlisib (100 mg per day) or matching placebo starting on day 1 of cycle 1, plus intr
133 1 to receive oral buparlisib (100 mg/day) or matching placebo, starting on day 15 of cycle 1, plus in
140 tered oral NAC (3000 mg in divided doses) or matching placebo 165 min before the infusion of saline a
141 al administration of 20 mg of doxycycline or matching placebo pill twice a day at least 2 days prior
142 o receive 10 mg/kg intravenous durvalumab or matching placebo 1-42 days after concurrent chemoradioth
143 0 mg of vitamin C and 400 IU of vitamin E or matching placebo between the 9th and 16th weeks of pregn
144 three), to receive once-daily eltrombopag or matching placebo dose adjusted from 50 mg to a maximum d
145 receive 150 mg of testosterone enanthate or matching placebo intramuscularly every 2 weeks for 6 mon
148 ctive dose of apomorphine sublingual film or matching placebo in a 12-week, double-blind maintenance
149 Patients received either fludrocortisone or matching placebo at highest tolerated doses from 0.05 mg
150 g/kg intravenous ramucirumab plus FOLFIRI or matching placebo plus FOLFIRI every 2 weeks until diseas
152 nation tenofovir-emtricitabine (TDF-FTC), or matching placebo--and followed monthly for up to 36 mont
154 ssigned to receive either subcutaneous GH or matching placebo titrated to the upper quartile of norma
158 s of radium-223 (50 kBq/kg intravenously) or matching placebo, with one injection given every 4 weeks
159 er kilogram of body weight intravenously) or matching placebo; one injection was administered every 4
162 assigned in a 3:2 ratio to oral ixazomib or matching placebo on days 1, 8, and 15 in 28-day cycles f
164 s either intravenous ramucirumab 10 mg/kg or matching placebo on day 1 of repeating 21-day cycles, un
168 nous injections of radium-223 (50 kBq/kg) or matching placebo; one injection was given every 4 weeks.
169 under double-blind conditions to lithium or matching placebo before receiving an additional three in
172 AH were to be randomized to aspirin 81 mg or matching placebo and simvastatin 40 mg or matching place
173 response system to oral rimegepant 75 mg or matching placebo every other day for 12 weeks (double-bl
175 tronidazole 750 mg plus miconazole 200 mg or matching placebo for 5 consecutive nights each month for
177 eive rimegepant orally at a dose of 75 mg or matching placebo for the treatment of a single migraine
179 Patients received atezolizumab 840 mg or matching placebo intravenously on day 1 and day 15 of ev
181 s were assigned to empagliflozin of 10 mg or matching placebo once daily on guideline-driven HF thera
186 Patients received oral vorinostat 300 mg (or matching placebo) twice daily on days 1, 2, 3, 8, 9, 10,
187 The study drugs (acetylcysteine 1200 mg or matching placebo) were administered orally twice daily f
188 to receive subcutaneous evolocumab 420 mg or matching placebo, administered in-hospital and after 4 w
190 cycle 1) with either capivasertib 400 mg or matching placebo, orally twice daily on an intermittent
193 omly assigned (1:1) to gefitinib (500 mg) or matching placebo by simple randomisation with no stratif
194 e randomized to receive ezetimibe (10 mg) or matching placebo for 6 months in addition to usual treat
195 ts per day of sodium clodronate (2080 mg) or matching placebo for up to 3 years (metastatic disease)
196 se of SCH 530348 (10 mg, 20 mg, or 40 mg) or matching placebo in a 3:1 ratio in a multicentre interna
197 ed 1:1 to receive escitalopram (10-20 mg) or matching placebo in addition to optimal heart failure th
198 ive either NDI-010976 (20, 50, or 200 mg) or matching placebo in period 1, followed by the alternate
200 1:1:1 ratio to ozanimod (0.5 mg or 1 mg) or matching placebo once daily for 24 weeks by an independe
202 either a low dose of varenicline (0.5 mg) or matching placebo pill (double-blind, random order) befor
203 e 4) to receive either denosumab (120 mg) or matching placebo subcutaneously every 3-4 weeks, startin
204 e) by site staff to receive PA101 (40 mg) or matching placebo three times a day via oral inhalation f
205 of ABI-H0731 (100, 300, 600, or 1000 mg) or matching placebo, or once-daily or twice-daily doses of
209 ions of AMG 145 70 mg, 105 mg, or 140 mg, or matching placebo every 2 weeks; or subcutaneous injectio
212 mg], n = 50 [30 mg], and n = 51 [40 mg]) or matching placebo (n = 76) for 20 weeks of treatment.
213 ing ephedra [12 mg] and caffeine [40 mg]) or matching placebo were administered in a crossover fashio
214 ng per kilogram of body weight per minute or matching placebo for 48 hours, in addition to accepted t
215 ly assigned to either NV1FGF at 0.2 mg/mL or matching placebo (visually identical) in a 1:1 ratio.
217 of 50 mug, 150 mug, 300 mug, or 600 mug, or matching placebo (n=55 in each group), or to open-label
218 fixed-dose tablets (also known as NB16), or matching placebo twice a day, given orally for 56 weeks.
224 ase inhibitor voxilaprevir (150 patients) or matching placebo (150 patients) once daily for 12 weeks.
228 the biomarker-directed arm, prednisolone or matching placebo was given according to the blood eosino
229 containing either 400 mg of progesterone or matching placebo twice daily, from the time at which the
230 ocated by computer to either the quadpill or matching placebo for 4 weeks; this treatment was followe
231 specific volume of study drug (reslizumab or matching placebo) on the basis of the patient's body wei
233 ceive 420-mg silymarin, 700-mg silymarin, or matching placebo administered 3 times per day for 24 wee
238 received oral cabotegravir 30 mg tablets or matching placebo once daily during a 4 week oral lead-in
242 ere randomized in a 1:1 ratio to warfarin or matching placebo for a planned treatment period of 48 we
245 (at a target dose of 15 to 20 mg weekly) or matching placebo in 4786 patients with previous myocardi
248 f dalteparin per kilogram of body weight) or matching placebo administered subcutaneously twice daily
250 g or 5.25 mg per kilogram of body weight) or matching placebo, given in two or four short courses for
256 d) plus alpha-lipoic acid (ALA; 600 mg/d) or matching placebos for 6 months (NCT00237718); 238 patien
257 y) with ribavirin (1000 or 1200 mg daily) or matching placebos during the 12-week double-blind period
259 biraterone acetate plus prednisone group) or matching placebos plus ADT (placebo group); each treatme
262 =628), 440 mg albendazole and a praziquantel-matching placebo (n=625), 40 mg/kg praziquantel and an a
268 cadazolid 250 mg twice daily with vancomycin-matching placebo capsule four times daily or oral vancom
269 iacin with 40 mg of laropiprant daily versus matching placebo, in addition to effective statin-based
274 n E (alpha-tocopherol) 1,000 U daily, versus matching placebos in 1,005 asymptomatic, apparently heal
275 ablet containing either 0.625 mg/d of CEE vs matching placebo; in the estrogen plus progestin trial,
281 igate oral iron polysaccharide compared with matching placebo with the primary end point of change in
282 placebo, for aspirin alone as compared with matching placebo, and for the polypill plus aspirin as c
283 omes for the polypill alone as compared with matching placebo, for aspirin alone as compared with mat
284 ve either oral tamoxifen 20 mg per day (with matching placebo in place of anastrozole) or oral anastr
285 zole) or oral anastrozole 1 mg per day (with matching placebo in place of tamoxifen) for 5 years.
287 75 mg bictegravir or 50 mg dolutegravir with matching placebo plus the fixed-dose combination of 200
297 ibavirin versus oseltamivir monotherapy with matching placebo for the treatment of influenza in 50 si
298 0 IU of oxytocin intramuscularly, along with matching placebos for the treatment they did not receive
300 pitavastatin 4 mg or pravastatin 40 mg with matching placebos once daily orally for 12 weeks, follow