ライフサイエンスコーパス: maternally-expressed

1 e imprinted Dlk1-Meg3 gene locus and is only maternally expressed.

2 f 4 miRNAs (e.g., miR-377, miR-379) from the maternally expressed 14q32 chromosome region.

3 s MALAT1, taurine upregulated gene 1 (TUG1), maternally expressed 3 (MEG3), linc00657, and linc00493.

4 We conclude that maternally expressed Activin-like signals do not act bef

5 We isolated a maternally expressed and dorsal organizer localized memb

6 Galanin mRNA was maternally expressed and found in developing fish throug

7 ver, the second hoxc13 ortholog, hoxc13b, is maternally expressed and is detectable in every cell of

8 e techniques demonstrated that Yes kinase is maternally expressed and is localized to the cortical re

9 encoded by the mini spindles (msps) gene, is maternally expressed and loaded into the egg, where it i

10 Xenopus development, gtpbp2 transcripts are maternally expressed and localized to the egg animal pol

11 use homologue (Grb10/Meg1) is reported to be maternally expressed and maps to the imprinted region of

12 Tsix is maternally expressed and mice carrying a Tsix deletion s

13 As in eutherians, marsupial H19 is maternally expressed and paternal methylation upstream o

14 ation revealed that zebrafish scube1 mRNA is maternally expressed and widely distributed during early

15 RNA was shown by in situ hybridization to be maternally expressed and widely distributed in the syncy

16 The most 5' of these is maternally expressed, and encodes neuroendocrine secreto

17 NAs, including miR-127, are processed from a maternally expressed antisense Rtl1 transcript (Rtl1as)

18 For example, a previously unnoticed, maternally expressed antisense transcript was mapped wit

19 Unlike a zygotically expressed gene, a maternally expressed aposematism gene will be hidden fro

20 Zebrafish tbl3 is maternally expressed, but later in development its expre

21 on, and of geminin, sox3 and zic2, which are maternally expressed, by late gastrulation.

22 The maternally expressed C. elegans gene spd-5 encodes a cen

23 lthough genetic screens have identified many maternally expressed cell fate-controlling RNA-binding p

24 neuroendocrine-specific protein (NESP55), a maternally expressed chromogranin-like protein.

25 Maternally expressed DE-cad(ex) result in phenotype with

26 th respect to perturbations to the dosage of maternally-expressed dorsal mRNA.

27 is transcribed embryonically, but unlike the maternally expressed Drosophila hb, its mRNA is not dete

28 . kcnh1a and kcnh1b) and that both genes are maternally expressed during early development.

29 The role of the majority of these maternally expressed factors is not fully understood.

30 For example, a maternally expressed Gal4-Sp1 fusion protein can functio

31 Using maternally expressed Gal4/Dorsal fusion proteins, we hav

32 In this study, we demonstrate that lncRNA maternally expressed gene 3 (Meg3) interacts with the RN

33 Maternally expressed gene 3 (MEG3) is an imprinted gene

34 Maternally expressed gene 3 (MEG3) is an imprinted gene

35 The long non-coding RNA (lncRNA) Maternally Expressed Gene 3 (Meg3) is encoded within the

36 The expression of maternally expressed gene 3 (MEG3) is selectively lost i

37 enomic imprinting at the Delta-like 1 (Dlk1)-Maternally expressed gene 3 (Meg3) locus is regulated by

38 lncRNA in malignant hepatocytes, among which maternally expressed gene 3 (MEG3) was downregulated by

39 Among them, the lncRNA maternally expressed gene 3 (Meg3) was found to be mostl

40 Delta, Drosophila, Homolog-like 1 (DLK1) and Maternally Expressed Gene 3 (MEG3).

41 CTC-binding factor (CTCF) recruitment to the maternally expressed gene 3 differentially methylated re

42 These results show that a single maternally expressed gene controls the patterning of the

43 The maternally expressed gene DLX5 showed a loss of imprinti

44 h loss-of-function mutations in p57(KIP2), a maternally expressed gene encoding a G(1) cyclin-depende

45 lements use microRNA-mediated silencing of a maternally expressed gene essential for embryogenesis, w

46 (KIP2), the product of CDKN1C, an imprinted, maternally expressed gene in a series of these rare, bip

47 Tumorhead (TH) is a maternally expressed gene in Xenopus laevis, that when o

48 otypic spectrum of BWS might depend on which maternally expressed gene is mutated.

49 We have found that mutations in the maternally expressed gene let-99 affect spindle orientat

50 Mutations in the maternally expressed gene mex-1 disrupt the segregation

51 the AS gene and suggest the possibility of a maternally expressed gene product in addition to the bia

52 ally expressed growth promoter, and H19 is a maternally expressed gene that can suppress growth in so

53 in an embryonic cell called P(1) requires a maternally expressed gene we name spn-4.

54 indicating that deficiency of an imprinted, maternally expressed gene within the critical interval i

55 line, RC-K8; Drosophila ME31B, encoded by a maternally-expressed gene, and Saccharomyces pombe Ste13

56 Here we show that imprinted Maternally expressed gene1 (Meg1) in maize is both neces

57 We report here a novel gene, maternally expressed gene1 (meg1), which shows a materna

58 in many species involves interactions among maternally expressed genes (eg, mRNA's and proteins plac

59 essed genes (PEGs), while endosperm-specific maternally expressed genes (endo-MEGs) were associated w

60 erations in imprinted genes, we analysed two maternally expressed genes (Igf2r, H19) and two paternal

61 inted genes in maize endosperm, including 54 maternally expressed genes (MEGs) and 46 paternally expr

62 In the rice endosperm, we identified 162 maternally expressed genes (MEGs) and 95 paternally expr

63 However, only approximately 14% of maternally expressed genes (MEGs) and approximately 29%

64 ed expression, and approximately half of all maternally expressed genes (MEGs) are DE in this study.

65 The majority of maternally expressed genes (MEGs) were shared among all

66 genes at this stage, while nearly 80% of the maternally expressed genes (MEGs) were specific to 10 DA

67 egion (IG-DMR) is required for expression of maternally expressed genes and repression of silenced pa

68 Studies of about 20 maternally expressed genes are providing an understandin

69 Surprisingly, the three maternally expressed genes are regulated very differentl

70 elate with allele-specific expression of two maternally expressed genes in the seed and that one DMR

71 role for IPW in modulating the expression of maternally expressed genes in trans, which has important

72 Additionally, by targeting maternally expressed genes of unknown function in zebraf

73 gulates imprinted expression of a cluster of maternally expressed genes on human chromosome 11p15.5.

74 Our gene ontology analysis implies that maternally expressed genes tend to decrease the length o

75 We also identify maternally expressed genes that may be regulated by unkn

76 imprinted genes and is demarcated by the two maternally expressed genes Tssc3 (Ipl) and H19 which are

77 ompletely abolished expression of downstream maternally expressed genes, activated expression of sile

78 chromosome 7 that contains a cluster of four maternally expressed genes, H19, Mash2, Kvlqt1, and p57(

79 is paternally expressed and is surrounded by maternally expressed genes.

80 ave so far been found in three of the linked maternally expressed genes.

81 downstream of OVO are known to be essential maternally expressed genes.

82 ic expression of Kcnq1ot1 and suppression of maternally expressed genes.

83 e sex, and the opposite sex is determined by maternally-expressed genes in individuals without the do

84 Maternally expressed GLP-1 participates in two of at lea

85 XLalphas, XLN1, and ALEX or a double dose of maternally expressed Gsalpha to phenotype has not been e

86 The maternally expressed GTL2 (gene trap locus 2) gene encod

87 , we show that Dlk1 is tightly linked to the maternally expressed Gtl2 gene.

88 encodes a potent fetal growth factor and the maternally expressed H19 encodes a non-coding RNA.

89 locus, H3K79me3 was paternally biased at the maternally expressed H19 locus, including the paternally

90 Hence, Sebox is a maternally expressed homeobox gene.

91 ts on cognitive processes and identify a new maternally expressed imprinted gene candidate on the X c

92 MEG3 is a maternally expressed imprinted gene suggested to functio

93 However, unlike in mammals, Meg1 is a maternally expressed imprinted gene that surprisingly ac

94 milar phenotype to mice with a knockout of a maternally expressed imprinted gene, Ascl2 [achaete-scut

95 that SRS may result from overexpression of a maternally expressed imprinted gene, rather than from ab

96 Maternally expressed imprinted genes are enriched for hy

97 vated in the hybrid, demonstrating that also maternally expressed imprinted genes are perturbed durin

98 es to identify 9 paternally expressed and 34 maternally expressed imprinted genes in A. thaliana endo

99 ancer suggest the involvement of one or more maternally expressed imprinted genes involved in embryon

100 The maternally expressed imprinted genes p57kip2 and M6P/Igf

101 t the placenta tends to display an excess of maternally expressed imprinted genes, with the addition

102 Here, bioluminescent reporters for the maternally-expressed imprinted gene Cdkn1c are used to e

103 n syndrome gene, has, to date, been the only maternally expressed, imprinted gene identified within t

104 dence that the disorder is associated with a maternally expressed, imprinted gene mapping to chromoso

105 difies the role of MDR1 in the regulation of maternally expressed, imprinted genes and TEs and identi

106 pressed biallelically in most tissues but is maternally expressed in almost all neurons.

107 As Notch is maternally expressed in macromeres, additional component

108 The mouse Kcnq1 gene is maternally expressed in most fetal but biallelically tra

109 at the Ido1 and Ido2 genes are imprinted and maternally expressed in mouse placentas.

110 show that AGL36-like genes are imprinted and maternally expressed in seeds of Arabidopsis species and

111 G(S)alpha is maternally expressed in some tissues and biallelically e

112 we found 10 novel imprinted genes that were maternally expressed in the placenta.

113 We found Rtl1 was paternally, but not maternally, expressed in brain stem, thalamus, and hypot

114 the opposite orientation with respect to the maternally expressed KvLQT1 gene.

115 otein-coding genes (DLK1, RTL1 and DIO3) and maternally expressed lncRNAs (MEG3/GTL2, RTL1as and MEG8

116 Maternally expressed members of the Transforming Growth

117 afish futile cycle gene is shown to encode a maternally expressed membrane protein required for nucle

118 These data suggest maternally expressed miRNAs antagonize paternally driven

119 ced neuron (iN) culture system, we show that maternally expressed miRNAs from the miR-379/410 cluster

120 al mode of inheritance - encodes a number of maternally expressed miRNAs.

121 XLerk exists as a maternally expressed mRNA, however, expression of transc

122 Most targets are maternally expressed mRNAs that accumulate in the absenc

123 l proteins that are encoded by nonlocalized, maternally expressed mRNAs.

124 The maternally expressed mutant Gnas transcript is the candi

125 nas1 gene region contains closely juxtaposed maternally expressed (Nesp) and paternally expressed (Ne

126 istal chromosome 12 and consists of multiple maternally expressed non-coding RNAs and several paterna

127 In addition, 35 maternally expressed non-coding RNAs exhibited the same

128 otein-coding genes Dlk1 and Dio3 and several maternally expressed non-coding RNAs, including Gtl2 and

129 otein-coding genes and for activation of the maternally expressed non-coding RNAs: its absence causes

130 s separated by approximately 100 kb from the maternally expressed noncoding gene H19 on mouse distal

131 is an imprinted locus consisting of multiple maternally expressed noncoding RNA genes and paternally

132 A group of maternally expressed NRPD1-siRNA loci targets endosperm-

133 Xenopus nuclear factor 7 (xnf7) is a maternally expressed nuclear protein that is retained in

134 ion in C. elegans, activities encoded by the maternally expressed par genes appear to establish cellu

135 The maternally expressed par genes are required for establis

136 elegans embryo requires the activity of the maternally expressed par genes.

137 yzed the allelic methylation patterns of the maternally expressed, paternally methylated H19 gene dur

138 permits faster genetic change than does the maternally expressed pattern at low frequencies of a fav

139 requencies of a favored allele, however, the maternally expressed pattern is again more conducive to

140 When selection is strong, the maternally expressed pattern of imprinting allows faster

141 In the early Caenorhabditis elegans embryo, maternally expressed PIE-1 protein is required in germ-l

142 iple genes, including the genes encoding the maternally expressed placental-specific transcription fa

143 Recent discoveries point to maternally expressed proteins required for cellular func

144 ation then influences the stability of other maternally expressed proteins that in turn determine ear

145 out a two-hybrid screen in yeast to identify maternally expressed proteins that interact directly wit

146 Here we report the cloning of HDm, a maternally expressed putative deposition histone deacety

147 Xenopus nuclear factor 7 (xnf7) is a maternally expressed putative transcription factor that

148 In the Drosophila embryo, Dorsal, a maternally expressed Rel family transcription factor, re

149 nal knockout (cKO) of Smc5 demonstrated that maternally expressed SMC5 protein is essential for early

150 onic day 12.5 (e12.5) embryos, where Meg3 is maternally expressed, the paternal Meg3 DMR was methylat

151 essed from the maternally inherited allele ("maternally expressed") to explore the molecular and cell

152 ethal underdominance (UD(MEL)), in which two maternally expressed toxins, located on separate chromos

153 ext]), and lower expression of h19 imprinted maternally expressed transcript (H19) ([Formula: see tex

154 ontaining 1 gene (ZMIZ1), and H19, imprinted maternally expressed transcript gene (H19) were associat

155 possibility that deficiency of an undefined, maternally expressed transcript or isoform of the UBE3A

156 ssion quantitative trait locus (eQTL) of the maternally expressed transcription factor KLF14 acts as

157 Skn-1 is a maternally expressed transcription factor that specifies

158 Maternally expressed transcription factors are essential

159 that act as enhancers of prenatal growth and maternally expressed transcripts that act as inhibitors

160 Because attempts to identify any novel maternally expressed transcripts were unsuccessful and b

161 The kinship theory predicts that maternally expressed transcripts will favor higher level

162 show that the human H19 locus also encodes a maternally expressed, translated gene, antisense to the

163 Here, we uncover and characterize a novel, maternally expressed, TRIM28-interacting KRAB zinc-finge

164 also implies the existence of an imprinted, maternally expressed tumor suppressor gene on chromosome

165 -specific LOH/pLOH may reflect the loss of a maternally expressed tumor suppressor gene or the acquis

166 in during development, driven by the loss of maternally expressed UBE3A and silencing of the paternal

167 the AS-IC exhibit reduced expression of the maternally expressed UBE3A gene and biallelic expression

168 We investigated the role of the maternally expressed Ube3a gene in experience-dependent

169 expressed domain of the locus, excluding the maternally expressed Ube3a gene, and is conserved in rat

170 tures of AS are primarily due to the loss of maternally expressed UBE3A in the brain.

171 equivalent for cortical plasticity, and that maternally expressed Ube3a is required for normal experi

172 eurogenetic disorder caused by deficiency of maternally expressed ubiquitin-protein ligase E3A (UBE3A

173 We show that maternally expressed VegT controls the pattern of primar

174 be biallelically expressed or paternally or maternally expressed were consistent with expectations.

175 hat hybrid inviability is partially due to a maternally expressed X-linked PO locus and an imprinted

176 Furthermore, we show that the maternally expressed zebrafish Kinesin-1 Kif5Ba is a bin

177 ted in bi-allelic expression of the normally maternally expressed Zim2, whereas the maternal transmis