ライフサイエンスコーパス: maturing

1 and executive cognitive functions are still maturing.

2 aracterize HIV-1 particles that are actively maturing.

3 the underlying neural circuits are actively maturing.

4 adipocytes and reduced lipid accumulation in maturing 3T3-L1 preadipocytes, demonstrating an inhibito

5 lasm ensures the structural integrity of the maturing 40S subunit.

6 e, we show that En1 and En2 are expressed in maturing 5-HT neurons that will form the dorsal raphe nu

7 is the predominant functional En paralog in maturing 5-HT neurons, although a small contribution fro

8 reveal complex intrinsic functions for En in maturing 5-HT neurons, hence necessitating a reinterpret

9 abundance of two multiprotein modules within maturing adhesions, one regulated by Rap1 and one by ten

10 ertal transition.SIGNIFICANCE STATEMENT Late maturing adolescents usually show delayed growth and bon

11 normal or ablated neurogenesis, we find that maturing adult-born neurons are crucial only when memory

12 These findings indicate that maturing adult-born neurons regulate both functional net

13 Excitability is enhanced in maturing adult-born neurons, spurring the hypothesis tha

14 After a decade or more, maturing adults migrate back to the Sargasso Sea, spawn,

15 influenced by the proportions of naive cells maturing along regulatory T cell, Th1, Th2, or Th17 phen

16 These data provide a maturing, although still incomplete, elucidation of the

17 This pattern is unique to the maturing and adult nervous system, as it requires the in

18 stems, beginning of integration between late maturing and early maturing brain structures, and develo

19 es, we compared functional responses of both maturing and established granule cells.

20 iding in phagosomes, which they prevent from maturing and fusing with lysosomes.

21 Biofabrication is maturing and growing, and scientists with different back

22 y, the analysis of IgM and IgD expression by maturing and mature naive B cells demonstrated an elevat

23 However, such studies are maturing and may foster clinical research, with opportun

24 We provide evidence of a maturing and more competitive stem cell workforce and di

25 The open access movement is maturing and must be embraced in some format.

26 sults should aid in the development of early-maturing and productive Upland cultivars with superior f

27 possibly standardize methods for producing, maturing, and mechanically interrogating iPSC-derived ca

28 However, the technology is still maturing, and the design elements for successful PROTAC-

29 FAs promotes mechanosensing and durotaxis by maturing, and thus reinforcing, FAs.

30 production process that allowed the skins of maturing animals of several species to be rendered into

31 During maturing antibody responses the increase in affinity for

32 initiation and becomes more dense with time, maturing as early as 14 days after wounding.

33 lterations, that preferentially impact later-maturing associative cortices important for higher cogni

34 The elevated susceptibility of early maturing axons to ischemic injury described here may sig

35 chpilot and Rim-binding protein complexes at maturing AZs.

36 tion and mutation process takes place in the maturing B cell and is responsible for the diversity of

37 ed canonical TGFbeta/BMP signaling in either maturing basal VSNs (bVSNs) or all mature VSNs.

38 antibodies could modulate SYK expression in maturing basophils and whether interaction with FcgammaR

39 Compared to salmon maturing before 1990, the reduced size of adult salmon a

40 tion Tshz1 in the transcriptional network of maturing beta-cells and suggest that its dysregulation c

41 Therefore, maturing Bienertia chlorenchyma cells provide a unique o

42 lic heterogeneity and proliferation within a maturing biofilm population, rather than a subtractive p

43 pendent effects in HSC and distinct roles in maturing blood cells.

44 the formation of a smooth muscle layer in a maturing blood vessel.

45 blood neutrophil subsets arise from distinct maturing bone marrow neutrophil subsets.

46 is study aimed to assess their impact on the maturing brain 20 to 30 years after diagnosis, providing

47 integration between late maturing and early maturing brain structures, and development of effective

48 disease, impacting thousands of exons in the maturing brain, heart and muscle.

49 ession profile, before folding begins in the maturing brain, was significantly different in the devel

50 ation factors and is highly expressed in the maturing brain.

51 RF-7 isoforms also occurred in the brains of maturing C57BL/6J mice.

52 the aorta at stem sites where they surround maturing CAs in both mouse and human hearts.

53 ocess of heme a biosynthesis and transfer to maturing CcO.

54 role of endocytic membrane remodeling in the maturing cell plate while the plate is stabilized by cal

55 are either required to provide the influx of maturing cells (such as hematopoietic stem cells) or whi

56 In wild-type sepals, ROS accumulate in maturing cells and limit organ growth, suggesting that R

57 These maturing cells transition from a proliferative state to

58 As maturing CGNs become more hyperpolarized, NFATc4 binding

59 erweight/obese children (RR = 0.81), earlier maturing children (RR = 0.93), and those who spent more

60 J is the major ribonuclease responsible for maturing chloroplast mRNA 5' termini, with RNA-binding p

61 quired to control FGFR1-Ras-ERK signaling in maturing chondrocytes in vivo.

62 expressed in condylar chondroprogenitors and maturing chondrocytes that also expressed the Indian hed

63 everal hours after p107 dephosphorylation in maturing chondrocytes.

64 late neurons (SPNs) form one of the earliest maturing circuits in the cerebral cortex and are crucial

65 ry cargo will be continuously present within maturing cisternae as resident Golgi proteins arrive and

66 biosynthetic vacuolar cargo depart from the maturing cisternae?

67 ng across stable cisternae and the other on "maturing" cisternae that carry cargo forward while progr

68 diator in augmenting metabolic energetics in maturing CMs.

69 or lacking from mature CNS axons by studying maturing CNS neurons in vitro.

70 capacity, which declines developmentally in maturing CNS neurons.

71 ended on factors having strong expression in maturing cone precursors and crucial roles in retinoblas

72 the number of interneurons integrating into maturing cortical networks.

73 he combination of traditional culturing with maturing culture-free approaches and phylogenomics shoul

74 t for heme a biosynthesis and/or transfer to maturing cytochrome c oxidase.

75 Based on a large-scale proteome analysis of maturing DCs, we identified the GPI-anchored protein sem

76 Second, DD blocked Stat3 phosphorylation in maturing DCs.

77 ell activation by dasatinib, pretreatment of maturing dendritic cells (DCs) with dasatinib strongly e

78 Despite the rapidly maturing device technology for silicon spin qubits(11-16

79 tic relationships that reflects a strong and maturing discipline.

80 tlantic bluefin tuna are managed as an early-maturing eastern stock, which spawns in the Mediterranea

81 Some maturing endocrine-restricted NeuroD1(+) cells in the pa

82 ated tegument protein pp150 is released from maturing endosomes and migrates to the nucleus, whereas

83 changing potassium concentration ([K(+)]) of maturing endosomes to release their genomes at the appro

84 siRNA release occurred invariably from maturing endosomes within ~5-15 min of endocytosis.

85 from host cells impairs K(+) accumulation in maturing endosomes, revealing new insights into endosoma

86 MYB118 is transcriptionally induced in the maturing endosperm, and seeds of myb118 mutants exhibit

87 DSTYK is highly expressed in the maturing epithelia of all major organs, localizing to ce

88 nd CH235.12 (week 323, 90%) demonstrated the maturing epitope to focus on the conformationally invari

89 ce died by E16.5, with profound reduction of maturing erythroblast populations within the fetal liver

90 In particular, maturing erythroblasts required Spi2A for cytoprotection

91 e via an EPOR-Spi2A serpin-cathepsin axis in maturing erythroblasts, with lysosomal cathepsins as nov

92 erythropoietin (EPO) to favor iron supply to maturing erythroblasts.

93 specialized roles supporting enucleation of maturing erythroblasts.

94 ear condensation, a morphological feature of maturing erythroblasts.

95 rlying the high-level expression of GATA1 in maturing erythroid cells have been studied extensively,

96 h PGC-1 proteins are abundantly expressed in maturing erythroid cells.

97 (EPO) provides the major survival signal to maturing erythroid precursors (EPs) and is essential for

98 tors is associated temporally with a wave of maturing erythroid precursors in marrow and with emergen

99 Vinculin slowed F-actin flow in maturing FA to establish a lamellipodium-lamellum border

100 l subset assembled in or was captured within maturing FA, and this behavior was promoted by active Ra

101 From the six first maturing females, five all homozygous clonal lines were

102 Within maturing fibres of host zebrafish embryos, our analysis

103 t describes the mechanical properties of the maturing fibrin network based on it structural quantitie

104 A constitutive model for the maturing fibrin network is developed that captures the e

105 lourished from almost nothing into a rapidly maturing field of research.

106 vasive, light delivery probes leveraging the maturing field of silicon photonics, enabling massively

107 Computational enzymology is a rapidly maturing field that is increasingly integral to understa

108 evolution favoring faster-growing or earlier-maturing fish, or a combination of these processes.

109 s, we determined gene expression patterns in maturing flow-sorted 5-HT neurons and the temporal requi

110 atushka2S produced the brightest and fastest maturing fluorescence in all experimental setups.

111 motor response control regions provide early-maturing foundational capacities and suggest that some e

112 We identified fast-maturing FPs from this set that yielded the highest sign

113 bstrate-enabled CTC/CFNC assays are observed maturing from enumeration and subclassification to molec

114 h CD8 T cells are known to acquire KIRs when maturing from naive to terminally differentiated cells,

115 The study of de novo protein-coding genes is maturing from the ad hoc reporting of individual cases t

116 mponents of behavior mediated in part by the maturing frontal lobe.

117 this study, we demonstrate that hPSC-derived maturing GABAergic interneurons (mGINs) migrate extensiv

118 Recombinant wild-type SEMA3E protected maturing GnRH neurons from cell death by triggering a pl

119 mpare here tFTs composed of different faster-maturing green fluorescent proteins (greenFPs) while kee

120 ding osteal macrophages, predominated in the maturing hard callus.

121 ardial organ migrate, adhere and envelop the maturing heart, forming the epicardium.

122 rine progenitor cells and next maintained in maturing hormone-expressing cells during pancreas develo

123 rases assist in assembling the H-cluster and maturing hydrogenases into their catalytically active fo

124 ecular mimicry, mAb 2D10 was isolated from a maturing immune response elicited against methyl alpha-d

125 CD8(+) T cells maturing in CD4-sufficient hepatocyte recipients develop

126 the blood, suggesting that B cells continued maturing in situ.

127 However, CD8(+) T cells, maturing in the absence of CD4(+) T cells, mediate cytot

128 CD4 thymocytes maturing in the altered thymic epithelial environment of

129 Dendritic cells maturing in the presence of sCD200 serum could induce po

130 y of a cohort of NFI-dependent genes in CGNs maturing in vivo.

131 hifts towards young, small, and more quickly maturing individuals.

132 parental generation being more skilled than maturing individuals.

133 tin accessibility and gene expression in the maturing intestine.

134 on ( 40% tyrosine hydroxylase (TH) positive, maturing into 25% cells exhibiting mDA neuron-like spiki

135 s physiologically relevant and is capable of maturing into a complete 50S particle.

136 y arresting the normal process of phagosomes maturing into acidified phagolysosomes.

137 , but not veins, contain pre-HSCs capable of maturing into dHSCs in the presence of exogenous interle

138 eates to form early SOS-signaling complexes, maturing into DNA-bound RecA bundles at later time point

139 2C-initiated progenitor cells are capable of maturing into functional keratinocytes.

140 transdifferentiating into myofibroblasts or maturing into lens fiber cells.

141 ls (OPCs) can repair demyelinated lesions by maturing into myelin-producing oligodendrocytes.

142 undergo selection for self-tolerance before maturing into their resting follicular B cell successors

143 tinct metabolic stages during development of maturing iPSC-CMs.

144 distribution and degree of polyclonality of maturing islets, as well as dispersion of progenitors wi

145 In conclusion, vaspin expression by maturing KCs modulates cutaneous immune responses and ma

146 a2 or Exo1 is required to supplement FEN1 in maturing lagging strands at telomeres.

147 ese processes do not occur in the absence of maturing leaves but can be restored by application of C(

148 the phosphorylation of lamin A/C and LFCD in maturing LFCs in vivo, as well as in dividing HLECs.

149 PI4KIIalpha is recruited to maturing lipopolysaccharide (LPS)-containing phagosomes

150 AERD is associated with eosinophils maturing locally in a high IFN-gamma milieu.

151 The fusion of maturing low-cost lithographic techniques with newer opt

152 cell reconstitution, particularly within the maturing M1 and M2 NK-cell subsets in association with e

153 septin GTPases associate preferentially with maturing macropinosomes in a phosphatidylinositol 3,5-bi

154 nal regulatory circuits that operates in the maturing mammalian brain.

155 line in the cell replacement capacity of the maturing mammalian ear.

156 We globally assessed IR in primary maturing mammalian erythroid and megakaryocyte (MK) line

157 ex, dynamic IR pattern has been described in maturing mammalian granulocytes, but it is unknown wheth

158 Longitudinal profiling of maturing, mature, granule-separated and pathogen-stimula

159 s localized to the developing pronephros and maturing MCCs, and loss of function altered formation of

160 Woody species are inherently slow maturing, meaning that seeders are confined to infrequen

161 In spite of maturing mechanistic understanding and new bioorthogonal

162 d progressive DNA methylation differences in maturing megakaryocytes.

163 endosomal tubular transport intermediates to maturing melanosomes and thereby promote cargo delivery

164 xpression, results in the deacidification of maturing melanosomes to support melanin synthesis.

165 ficking of tyrosinase-containing vesicles to maturing melanosomes.

166 pathway from recycling endosomal domains to maturing melanosomes.

167 es made frequent and prolonged contacts with maturing melanosomes; in contrast, tubules from BLOC-2-d

168 om its development and early challenges to a maturing modality that has provided unique insights into

169 ulate the expression of >8000 transcripts in maturing mouse dendritic cells (DCs) via regulation of s

170 In the maturing mouse enamel, the association of these residual

171 eloblastin and amelogenin interaction in the maturing mouse enamel.

172 amily localize to the developing acrosome of maturing mouse germ cells.

173 The scanning of maturing mRNAs by ribosomes plays a key role in the mRNA

174 Maturing MS/DB neurons in naive brain slices PD 4-16 sho

175 anglion cells, and late-stage progenitors or maturing Muller glia.

176 ped to support the contractile properties of maturing muscle fibers.

177 The maturing mutational landscape of cancer genomes, the dev

178 Maturing mutissues increased systolic force while simult

179 lated along the length of the stereocilia in maturing Myo6 mutant mice.

180 An alternative hypothesis posits that maturing neurons "indirectly" contribute to memory encod

181 lurane significantly decreased the number of maturing neurons and increased the number of astrocytes

182 ological development of synaptic inputs onto maturing neurons has restricted our understanding of how

183 proliferating cells and the number of newly maturing neurons in the hippocampus.

184 related activity patterns among ensembles of maturing neurons in the lateral geniculate nucleus (LGN)

185 l neurons is required for the integration of maturing neurons into the coordinated CPG network.

186 in contrast to astrocytes or young neurons, maturing neurons possess negligible Nrf2-dependent antio

187 llowing downregulation of programming TFs in maturing neurons remains unknown.

188 ms to be required for proper development: in maturing neurons, ectopic Nrf2 expression inhibits neuri

189 ew enhancers bound by clusters of Onecut1 in maturing neurons.

190 y before birth, both in progenitor cells and maturing neurons.

191 e into robust typological distinctions among maturing neurons.

192 elopment may be profoundly influenced by the maturing neurovascular and autoregulatory systems of the

193 Gene expression in maturing neutrophils requires combinatorial actions of l

194 activity, driving a reinterpretation of this maturing new technology during clinical translation.

195 droxyacetone (DHA) to methylglyoxal (MGO) in maturing New Zealand manuka honey, the kinetics of forma

196 umber and complexity of doublecortin-labeled maturing newborn neurons in the dentate gyrus subgranula

197 ivering cells into the lung scaffold and for maturing newly formed endothelium through co-seeding of

198 how sequential conformational changes in the maturing nucleocapsid control the ordered binding, first

199 Nug2 binds the inter-subunit face of maturing, nucleoplasmic pre-60S particles, and the locat

200 An involvement in the maturing of cytolytic peptides is very likely, due to hi

201 rst example of a PQM protease, essential for maturing of spider venom neurotoxins.

202 f recombinant toxic peptides, adapted to the maturing of spider venom toxins.

203 Maturing of the cream caused a transition from alpha- to

204 s myelination in OLP-neuron co-cultures, and maturing oligodendrocytes in spinal cord white matter di

205 During Drosophila oogenesis, RCs connect the maturing oocyte to nurse cells supporting its growth.

206 Because maturing oocytes and early embryos lack appreciable tran

207 Isolated maturing oocytes autonomously synthesized betaine in vit

208 onstrated the control of epigenetic marks in maturing oocytes by SGOC network.

209 also describes the stage specific growth of maturing oocytes within the ovary and permits the presen

210 stinct subset of mRNAs both in quiescent and maturing oocytes, a function recapitulated with YFP-3'UT

211 production in the fat body and Vg uptake by maturing oocytes, is of great importance for the success

212 38 and Rab32, to facilitate transport to the maturing organelle.

213 As for a maturing organism, PCa's epigenome is plastic and evolve

214 stress during intrauterine development of a maturing organism.

215 therefore restrict regenerative capacity in maturing organisms without compromising gene functions r

216 d deletion of RBPjk in skeletal progenitors, maturing osteoblasts, and committed chondrocytes.

217 e cells, and this concept may be expanded to maturing other PSC-derived cell types, including those c

218 response phase above 10 Hz when present: (1) maturing (P7-P9) type I hair cells acquired low-voltage-

219 Notably, the maturing particles did not stall while waiting for the p

220 fferentiation process and drive migration of maturing PCs through the dark zone and out of the GC.

221 However, in maturing pea (Pisum sativum) seeds, the level of the chl

222 s by imparting a specific structure into the maturing peptide that facilitates the ensuing reaction.

223 Endogenous caveolin-1 was recruited to maturing phagolysosomes in RPE cells in culture.

224 phosphate (PtdIns(4)P), which is abundant in maturing phagolysosomes, was depleted as they tubulated

225 gh acidification, such as would occur within maturing phagolysosomes.

226 s (associated with an inability to evade the maturing phagosome) and were significantly attenuated in

227 We show that in DCs, maturing phagosomes extend numerous long tubules several

228 se (NOX2), which generates superoxide within maturing phagosomes, has also been shown to regulate act

229 ection and progressively degrade them within maturing phagosomes.

230 ctor-free derivatives exhibited an expedited maturing phenotype with canonical responsiveness to adre

231 o, this regulation occurs selectively in the maturing plexus of the mouse developing retina, where An

232 ialylation of nephrin and podocalyxin in the maturing podocyte where it is required during the format

233 avonoids and their transport to the adjacent maturing pollen as the coat to serve various functions.

234 Cdc42 signaling induce the rearrangement of maturing pouch cells into bilayers through junctional lo

235 signaling increases junctional E-cadherin in maturing pouches.

236 The later-maturing prefrontal cortex is more sensitive to adolesce

237 ccumulation of presynaptic material at large maturing presynaptic boutons.

238 tive to adolescent exposure than the earlier-maturing, primary somatosensory cortex.

239 ion of this membrane network is conserved in maturing primitive and definitive erythroblasts despite

240 We conclude that maturing primitive erythroblasts initially navigate the

241 eflect this study's focus on relatively late-maturing psychological processes, particularly the appra

242 on(2) and has been proposed to sensitize the maturing psychophysiological stress system to stress in

243 In these embryos, the maturing pulmonary venous plexus does not anastomose uni

244 number and total dendritic branch length in maturing rat neurons and is sufficient to promote dendri

245 of adult neurogenesis--but was restricted to maturing, rather than proliferating, neuronal precursor

246 ry of moderate levels of IDUAe1 derived from maturing red blood cells, 2% to 3% of normal brain IDUA

247 Ts have been constructed by combining slower-maturing red fluorescent proteins (redFPs) with the fast

248 proteins (greenFPs) while keeping the slower-maturing redFP constant (mCherry).

249 In contrast, slower maturing regions, such as the PFC, have been suggested t

250 d stable; they out-performed the three early maturing released hybrids in WCA.

251 on of the miRNA-processing enzyme Dicer from maturing renal tubules produces tubular and glomerular c

252 INGS: Because tortoises are long-lived, late-maturing reptiles, we assessed the progress of the trans

253 -scale 'elephant trap' predominantly removes maturing savanna trees in the 5-9 m height range.

254 y transferred from growing inflorescences to maturing seeds, allowing offspring control over maternal

255 Although maturing sequencing technologies allow these experiments

256 hat CD16 is rapidly shed from the surface of maturing slanDCs, resulting from the combined action of

257 Kdm3a localizes to cytoplasmic structures of maturing spermatids affected in Kdm3a mutant mice, which

258 the epididymal fluid can be cytotoxic to the maturing spermatozoa resulting in male infertility.

259 nearly perfect gain scaling by virtue of the maturing spike-generating currents alone.

260 , vascular bundles and rind dissected from a maturing stalk internode of sugarcane, identifying ten c

261 ferentially in the storage parenchyma of the maturing stalk internode.

262 of water soluble carbohydrates (WSCs) in the maturing stem of temperate cereals and are an important

263 Image-based profiling is a maturing strategy by which the rich information present

264 pment of top-down inhibitory modulation from maturing subcortical and cortical brain networks.

265 luorescent proteins (redFPs) with the faster-maturing superfolder green fluorescent protein (sfGFP).

266 developmentally important role for Syt2a in maturing synapses in the forebrain, coinciding with the

267 e thymus, driving immunological tolerance in maturing T cells.

268 also show that TgCPL is capable of partially maturing TgCPB in vitro.

269 embly of this nanomaterial by expressing and maturing the EcHyd-1 hydrogenase prior to expression of

270 appearing around weaning in rats and slowly maturing thereafter [14,15].

271 PCR, and show that expression is confined to maturing thymocytes.

272 er B cells, bone marrow progenitor cells, or maturing thymocytes.

273 rive in the lungs during a late fetal stage, maturing to alveolar macrophages through a prealveolar m

274 )Foxp3(+) cells that are highly efficient at maturing to CD25(+)Foxp3(+) cells in response to IL-2.

275 Biomarker development is maturing to include a wide array of molecular measuremen

276 B cells maturing to produce autoantibodies in systemic autoimmun

277 Nutritional metabolomics is rapidly maturing to use small-molecule chemical profiling to sup

278 ogical recording and regulation tools and is maturing toward applications ranging from life sciences

279 eutics and viral gene therapies, are rapidly maturing towards widespread clinical use.

280 red for downregulation of ERBB2 signaling in maturing trabeculae.

281 inhibition of the CaN/NFATc pathway in CGNs maturing under physiological nondepolarizing conditions

282 ctile waves and their synchronization within maturing, unlabeled induced pluripotent stem cell-derive

283 alves, suggesting that accumulating Axin2 in maturing valves represents negative feedback that restra

284 increased because of the shift toward longer-maturing varieties during last three decades in the Chin

285 We report that modern, longer-maturing varieties have extended the growing period by a

286 ncreased requirement for water by the longer-maturing varieties.

287 (H) becomes less influential, likely because maturing VGNs also acquire low-voltage-gated potassium c

288 uring the lytic phase of the life cycle, the maturing viral particles undergo orchestrated translocat

289 The transient persistence of CA-SP in maturing virions and the identification of second-site m

290 ur results indicate that efficient egress of maturing virions and, in agreement with studies on murin

291 uggests that capsids assemble de novo inside maturing virions from dissociated capsid (CA) protein, b

292 increasing amounts later in infection in the maturing viroplasm, suggesting a conversion of dNSP2 int

293 spawns in the Mediterranean Sea, and a late-maturing western stock, which spawns in the Gulf of Mexi

294 The radiology AI marketplace is rapidly maturing, with an increase in product offerings.

295 ial genomic epidemiology, the field is still maturing, with many more exciting developments on the ho

296 yadenylation-induced translation of mRNAs in maturing Xenopus oocytes is the cytoplasmic polyadenylat

297 imilar ETC remodeling and glycogen uptake in maturing Xenopus oocytes, suggesting that these processe

298 Similar to M phase progression in maturing Xenopus oocytes, the destruction of CPEB during

299 Here, we examine myenteric plexus of the maturing zebrafish larval fish histologically over time

300 standing of myenteric plexus architecture in maturing zebrafish, thereby enabling functional studies