ライフサイエンスコーパス: meaningful

1 hange of >=6 points is considered clinically meaningful).

2 y changes >2 titers can be deemed clinically meaningful.

3 sonance is vital in making music emotionally meaningful.

4 tive of patient survival and more biological meaningful.

5 ion to decrease the rate would be clinically meaningful.

6 to ensure that our information measures are meaningful.

7 e information in order to make it clinically meaningful.

8 completed, many post-marketing studies lack meaningful active comparators, have observational design

9 platforms to make impactful discoveries and meaningful advances.

10 years were unified via DIMEDR, which enabled meaningful analysis across otherwise incomparable and un

11 To provide policy-makers and the public with meaningful and actionable environmentally-informed COVID

12 The 3.8-point difference is clinically meaningful and corresponds to an effect size of 0.59.

13 te stable, pembrolizumab provided clinically meaningful and durable antitumor activity with a managea

14 First-line pembrolizumab confers meaningful and durable clinical response in cisplatin-in

15 rally well tolerated and provided clinically meaningful and durable responses in patients with mUC; s

16 ists at all stages in their careers can make meaningful and habitual contributions to supporting incl

17 anding of these cells would be essential for meaningful and lasting treatments.

18 pass the range of factors that surgeons find meaningful and relevant.

19 n hospital files of intervention patients is meaningful and requires further study.

20 phisticated approaches are unable to provide meaningful answers when the user lacks a clear study que

21 crops through genetic engineering will be a meaningful approach to manage food production under the

22 currently insufficient evidence to establish meaningful ASD specificity of any genes based on large-e

23 not in isolation, to arrive at a clinically meaningful assessment; (4) a single Grade is assigned to

24 lore whether the sharing economy can provide meaningful assistance to reducing food waste in a relati

25 There was not a meaningful association between distance to a major roadw

26 returns a ranked list of papers that contain meaningful associations between the keywords.

27 ies and intra-individual variation highlight meaningful avenues for future theorizing and application

28 eters must be physiologically and physically meaningful based on the resolution of the instrument and

29 compounds in complex mixtures can produce a meaningful behavioural response, how small differences i

30 Clinically meaningful benefit might be restricted in an unselected

31 We found no evidence of clinically meaningful benefits of serum urate reduction with allopu

32 No statistically significant or meaningful benefits were observed for any outcome measur

33 anti-thymocyte globulin provides clinically meaningful benefits when added to standard GVHD prophyla

34 No clinically meaningful between-group difference in the incidence or

35 between platforms, but they may also remove meaningful biological differences among datasets.

36 re are few systematic efforts that integrate meaningful biological insights from these studies.

37 our protocol, we demonstrate how to evaluate meaningful biological interactions with CellPhoneDB v.2.

38 assign sounds in the world to behaviourally meaningful categories.

39 Although TMS treatment produced a clinically meaningful change in depressive symptom severity, this d

40 meet established thresholds for a clinically meaningful change.

41 literature-derived risk reductions showed no meaningful changes in MACE or ACM HRs or P values, altho

42 We identify ecologically meaningful changes in parameters that alter or destroy e

43 s safe and well tolerated with no clinically meaningful changes in safety parameters or adverse event

44 roperly chosen piecewise models might ignore meaningful changes or over-interpret noise-induced ones,

45 Clinically meaningful changes were defined a priori and linear regr

46 Our hypothesis is that the meaningful characteristics of the data will remain despi

47 Physically meaningful characterization of irregularly shaped partic

48 This has potentially meaningful clinical implications as the accuracy of the

49 ealthcare staff exposure with improvement in meaningful clinical outcomes.

50 employed to demonstrate that SPPA can reveal meaningful clusters in the data where other unsupervised

51 , there was a lack of strong correlations or meaningful clusters in the suggested therapeutic needs.

52 l anesthesia (GA), and hence is incapable of meaningful cognitive processing-the sole purview of waki

53 Qualitatively, MixEHR disease topics reveal meaningful combinations of clinical features across hete

54 high variability in treatment indications, a meaningful comparison in outcomes could not be made.

55 as matched to that of the rule of 5 to allow meaningful comparison of the "hit rate," or the proporti

56 t of quality improvement initiatives, making meaningful comparisons across hospitals and geographic r

57 action risk lacked enough available data for meaningful comparisons.

58 lassify discrete events and experiences into meaningful concepts.

59 solutions by attempting to obtain clinically meaningful conclusions at the end or during a trial, for

60 sweeping verbal generalizations that lack a meaningful connection to the statistical quantities they

61 potential to enhance physician presence and meaningful connection with patients in the clinical enco

62 thers and 'argument strength' must have some meaningful connection with truth.

63 education is required to ensure accurate and meaningful consideration of these concepts.

64 These findings suggest meaningful continuity between infant temperament and the

65 t least 2-3 GtCO(2) year(-1), and may make a meaningful contribution to mitigating climate change.

66 hours and 21.00 hours in the UK could make a meaningful contribution to reducing childhood obesity.

67 cle provides helpful guidance on how to have meaningful conversations about serious illness using tel

68 ncordantly, mitochondrial DNA failed to show meaningful CpG methylation.

69 ries, establishing a more targeted, fair and meaningful criterion to detect similarities.

70 nitive and motor worsening, using clinically meaningful cutoffs.

71 dual task walking may be utilized to capture meaningful data sensitive to the long-term impact of sym

72 parator trials exist, they might not produce meaningful data to inform decisions in clinical practice

73 However, generating meaningful data using confocal microscopy requires caref

74 ed to large clinical data sets may provide a meaningful data-driven approach to categorize patients f

75 sistent annotation to identify and interpret meaningful data.

76 he film flatness and rigidity for collecting meaningful data.

77 recommendations to guide researchers towards meaningful, data-driven discoveries in the science of em

78 with a signal-to-noise ratio of ~ 10 into a meaningful dataset for understanding internal flow and c

79 ding up to survey and child lifetime lead to meaningful declines in acute measures of child nutrition

80 virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral t

81 s information requires robust and physically meaningful decomposition of spectra into contributions f

82 e and desirable properties to achieve a more meaningful decomposition.

83 Our findings suggest that a small but meaningful decrease in firearm-related deaths may be ass

84 s that not only are distinguishable but to a meaningful degree are composed of entirely different mic

85 ater from the body, and result in clinically meaningful degrees of decongestion.

86 ib maintenance treatment led to a clinically meaningful delay in starting subsequent therapy and prov

87 et they were constantly failing to achieve a meaningful depth of quantitative proteome coverage withi

88 ation on modelled daily carbon gain causes a meaningful deviation of c. 18% day(-1) .

89 A meaningful difference in ICD failure rate was defined as

90 ly criticized for not identifying clinically meaningful differences between programs, and not providi

91 y decreases the power of studies to identify meaningful differences between samples, increases the li

92 tment (298 trials), there were no clinically meaningful differences between treatments for mortality

93 There are meaningful differences between young adults with and wit

94 s between measurements did not result in any meaningful differences from this directionality.

95 In men, no meaningful differences in CRC risk were observed for the

96 at were transplanted did not have clinically meaningful differences in graft survival and function.

97 the ICD Registry suggests that there were no meaningful differences in the rate of ICD high-energy le

98 Two meaningful dimensionless groups were discovered as the l

99 extent to which autonomous systems can make meaningful discoveries.

100 confers competitive performance and reveals meaningful disease-related topics.

101 Lastly, a clinically-meaningful distinction could be made amongst participant

102 re is little evidence for a climatologically meaningful 'dry season' in the Southeast because most ar

103 Tazemetostat monotherapy showed clinically meaningful, durable responses and was generally well tol

104 ted effective antitumor activity; clinically meaningful, durable responses; and acceptable safety in

105 havioural responses may be pivotal in making meaningful ecological inferences about observed patterns

106 sets are typically needed for establishing a meaningful EEM-PARAFAC model.

107 s with recent exposure excluded a clinically meaningful effect of hydroxychloroquine as postexposure

108 A therapeutic meaningful effect of MT2A knockdown and subsequent cispl

109 There was very limited evidence for a meaningful effect of smoking on MS susceptibility as mea

110 The ACP believes these changes will have a meaningful effect on patients without shifting costs to

111 e the statistical power required to detect a meaningful effect, potentially resulting in wasted resou

112 Further, no meaningful effects emerged when analysing women and men

113 lflufen plus dexamethasone showed clinically meaningful efficacy and a manageable safety profile in p

114 clear or consistent evidence for clinically meaningful efficacy of lower doses of IV ketamine.

115 ke popular GNNs, SkipGNN learns biologically meaningful embeddings and performs especially well on no

116 trial design, convenient participation, and meaningful end points and outcomes to improve patient re

117 Meaningful engagement of adolescent and young women woul

118 chanisms by which features become bound into meaningful episodes is a vital part of understanding how

119 Moreover, our method still yields meaningful estimates in very challenging situations, i.e

120 e CDS rules are adequately tested; 8) select meaningful evaluation measures; 9) use as rigorous a stu

121 However, metrics must be meaningful, evidence-based, attributable, and feasible t

122 , He, Ar, and Kr) combined with a physically meaningful excess air model, we quantified N(2) originat

123 ognitively engaging, emotional, and socially meaningful experiences.

124 ve been proposed to recover the biologically meaningful expression by borrowing information from simi

125 The detection and segmentation of meaningful figures from their background is one of the p

126 ual system is to parse complex 2D input into meaningful figures.

127 lly abundant microbial species is clinically meaningful for finding disease-related pathogenic or pro

128 ultiple specialties, this content outline is meaningful for medical student education, independent of

129 uperior to a chance forecaster, and provided meaningful forecasts in the majority of patients.

130 ying capacity, a cost may be required to see meaningful gains.

131 ractions allows identifying the biologically meaningful gene and sample subsets and improves the repr

132 nctional pathways and pre-defined biological-meaningful gene sets, revealing potential for regulatory

133 ances in mass spectrometry (MS) have enabled meaningful glycoproteomic undertakings, many technical l

134 We structured 8 meaningful groups of variables, and their relative impor

135 ed to reduce exposure to levels that produce meaningful health improvements.

136 in the may be appropriate group experienced meaningful health status benefits as well.

137 Tissue fingerprints are concise but meaningful histopathologic image representations that ca

138 approaches are likely to identify clinically meaningful HTE, methodological aspects of risk-modeling

139 al drug design approaches to test clinically meaningful hypotheses.

140 data analysis required to test biologically meaningful hypotheses.

141 Climate predictions are only meaningful if the associated uncertainty is reliably est

142 the minimum amount of weight loss to have a meaningful impact on cardiovascular health and survival

143 The rearing environment has a meaningful impact on risk for major depression, and this

144 as extent of retinal edema (CST) may have a meaningful impact on the anticipated variability between

145 ree-living microparasite survival can have a meaningful impact on the ecological dynamics of establis

146 These differences had no meaningful impact on the study results; hazard ratio for

147 unding process and structure aimed to make a meaningful impact on translating science into the clinic

148 ifications to hit or lead compounds can have meaningful impacts on pharmacological profiles due to si

149 This has meaningful implications for future clinical trials and c

150 lizumab 150 mg does not result in clinically meaningful improvement (high certainty) of the urticaria

151 was the proportion of eyes with a clinically meaningful improvement (increase of >=10 mm) in Schirmer

152 stuzumab emtansine did not show a clinically meaningful improvement in progression-free survival and

153 otherapy showed a significant and clinically meaningful improvement in progression-free survival vers

154 therapy provided a sustained and clinically meaningful improvement in RFS at 3-year median follow-up

155 scores was 2 points, considered a clinically meaningful improvement.

156 Clinically meaningful improvements (>=3 points increase) in HFMSE s

157 Omalizumab 300 mg results in clinically meaningful improvements (moderate certainty) of the UAS7

158 rity improvement on the DRSS, accompanied by meaningful improvements in BCVA.

159 E-1/2 experienced significant and clinically meaningful improvements in HRQoL measured by AE-QoL foll

160 5q spinal muscular atrophy, with clinically meaningful improvements in motor function in a real-worl

161 ant resulted in statistically and clinically meaningful improvements in nausea and reduced vomiting,

162 ociated with faster and sustained clinically meaningful improvements in PROs, including pain, in tran

163 Clinically meaningful improvements in quality of life were observed

164 osure to active iTBS demonstrated clinically meaningful improvements in the year following stimulatio

165 In addition, clinically meaningful improvements were seen in child-reported and

166 Reductions in pain with D-Rd were clinically meaningful in patients regardless of age, ECOG status, o

167 ctive health clinic, results in a clinically meaningful increase in subsequent use of effective contr

168 plinary background of the collaborators is a meaningful indicator of the type of interdisciplinary re

169 ization of perceptual inference could reveal meaningful individual differences in complex high-level

170 Extracting meaningful information from images obtained from such mi

171 technique (limited charge reduction) allows meaningful information to be obtained on the noncovalent

172 ate which stages of the approach can extract meaningful information, and also describe limitations of

173 ectories, even in short sounds, often convey meaningful information, which may be used to differentia

174 ernational research and clinical trials with meaningful input from patients.

175 priateness and utility of e-consults provide meaningful insight into practice, provide a rubric for c

176 in diverse aspects of cell biology, provide meaningful insights into processes such as N-terminal pr

177 ocket atoms, called BionoiScores, to provide meaningful insights into their interactions with ligand

178 n is required prior to data analysis to gain meaningful insights.

179 s effect on reducing disease spread provides meaningful insights.

180 ine learning methods to predict biologically meaningful interactions.

181 psychology-and-law author teams produce more meaningful interdisciplinary work, specifically in decis

182 ndividual SFAs, the likelihood of clinically meaningful interindividual variation in response to SFA

183 In transplant, meaningful international comparisons in organ utilizatio

184 uggest social participation and subjectively meaningful interpersonal interactions are related to phy

185 nnotation information to enable biologically meaningful interpretation and (iii) make full use of fin

186 of interest (ROIs) given their biologically meaningful interpretation and modest dimensionality comp

187 s an important role to play in assisting the meaningful interpretation of observed isotope effects fo

188 The lack of such data can limit meaningful interpretation of physical and chemical featu

189 Meaningful interpretation of such complex forms of big d

190 common cellular conditions can provide more meaningful interpretation of the cellular SAR analysis.

191 for any exposure versus not does not have a meaningful interpretation.

192 er causal inference methods can help us find meaningful interventions on these fundamental social dri

193 First, how meaningful is the relationship between responses to sacr

194 rrestin recruitment (k(tau)), a biologically-meaningful kinetic drug efficacy parameter, by fitting t

195 r clinical use is sustaining therapeutically meaningful levels of the active agent while minimizing s

196 The sense that one is living a meaningful life is associated with positive health outco

197 ich might have impeded the identification of meaningful links between niche features and spatial patt

198 tein) and vitamin D play causal roles of any meaningful magnitude in development of cardiometabolic d

199 Better defined NES should also allow meaningful mapping of cancer-related mutation positions,

200 ctional change will reveal more biologically meaningful markers of brain aging in health and disease.

201 Clinically meaningful mean change from baseline in the angioedema-q

202 formation recovered can produce biologically meaningful measurements of splicing in single cells.

203 e IOP reduction or sustained IOP control and meaningful medication reduction for up to 12 months post

204 dition, M2M identifies key species, that are meaningful members of the community for functions of int

205 ured cells, but whether this translates into meaningful metabolic benefits in vivo, wherein the dynam

206 the at-risk pool is large, and a clinically meaningful metric for risk stratification to guide inter

207 developed to process heterogeneous data into meaningful metrics, but often do not address how finding

208 studies documented improvement in clinically meaningful metrics, including tear breakup time (TBUT),

209 Clinically meaningful molecular subtypes for classification of brea

210 elated Internet search activity, can produce meaningful "nowcasts" of disease incidence ahead of heal

211 ents and produced 49 highly reproducible and meaningful object dimensions that reflect various concep

212 ing whether these variables are biologically meaningful or stemming from technical reasons remains a

213 w that EDGE is well suited for searching for meaningful organization of cells, detecting rare cell ty

214 ACDiT may be considered a meaningful outcome measure for comparing strategies for

215 h patients to determine their priorities for meaningful outcomes that should be used to measure progr

216 o-treat population but suggests a clinically meaningful overall survival benefit with atezolizumab pl

217 ed significantly greater and more clinically meaningful pain relief up to 12 months than open-loop sp

218 developed a stochastic model with physically meaningful parameters that can be utilized to optimize t

219 or the dignity of dying patients by creating meaningful patient- and family-centered memories while p

220 ets, we illustrate that RiboDiPA can uncover meaningful pattern differences across multiple biologica

221 denoising autoencoder framework can extract meaningful patterns corresponding to functional gene gro

222 ntaminants and other chemical noise) obscure meaningful patterns in MS data, complicating both compou

223 This study assessed the impact of clinically meaningful peak, midpoint, and trough concentrations of

224 to seamlessly transform into a coherent and meaningful perceptual experience.

225 None of the species showed meaningful phylogeographic patterns, possibly due to gen

226 There are meaningful physiological and technical achievements to r

227 s efficacy for assigning P into biologically meaningful pools remains unknown.

228 early identification and intervention have a meaningful potential for clinical actionability and a po

229 can give novel insight, and may deliver more meaningful prediction in both coding and non-coding regi

230 g monotherapy cell line data into clinically meaningful predictions of drug combination efficacy.

231 IC is a standalone application that produces meaningful predictions of TFs and cofactors in transcrip

232 ing explicitly tested, and thereby precludes meaningful predictions on the consequences of changing e

233 e physical manifold, resulting in physically meaningful predictions, and 2) cyclically consistent wit

234 trategies to integrate such information in a meaningful, predictive and experimentally verifiable way

235 st algorithms confirmed mountainousness as a meaningful predictor of personality when tested against

236 As a guide, we suggest three features of meaningful progress in the collaborative field, the neur

237 ur study involved only a small cohort, these meaningful proof-of-concept data now warrant further inv

238 A meaningful proportion of eyes never used the device or c

239 exiletine and lacosamide were effective in a meaningful proportion of patients but poorly tolerated.

240 Influenza vaccination gave meaningful protection against laboratory-confirmed influ

241 sing new workflow for fast and statistically meaningful quantification of materials defects.

242 clinicians translate secondary findings into meaningful recognition, treatment, and prevention of dis

243 Under open conditions, MST led to clinically meaningful reduction in depressive symptoms in patients

244 r the procedure, NSAIDs provide a clinically meaningful reduction in pain relative to a control group

245 eads-and-hearts hypothesis, which holds that meaningful reductions in achievement gaps only occur whe

246 Screening leads to meaningful reductions in deaths from cancers.

247 rge numbers of participants, and resulted in meaningful reductions in psychological distress at 3 mon

248 We show clinically meaningful reductions in the treatment time necessary to

249 stimuli (e.g., the tic of a clock) or detect meaningful repetition (e.g., consecutive tones in Morse

250 We show that the functionals learn a meaningful representation of the physical information co

251 t can model cell differentiation by building meaningful representations from the high dimensional and

252 Entrectinib induced durable and clinically meaningful responses in patients with NTRK fusion-positi

253 o highlighting the challenges in achieving a meaningful result from its use.

254 inarization must be appropriate and generate meaningful results, and the CC measurements calculated f

255 ed on previous studies, HLA3 clearly plays a meaningful role in HCO(3) (-) transport, but the functio

256 rated-omics analysis identified biologically meaningful RV bronchiolitis endotypes in infants, such a

257 graphic areas, and produces information on a meaningful scale for decision-making.

258 isplayed increased attention to semantically meaningful scene regions, suggesting more exploratory, i

259 d radicalization contributes to a robust and meaningful science of psychology.

260 ew of the fine-scale dynamics of complex and meaningful sensorimotor actions.

261 ts are methodologically valid and clinically meaningful should be an aspirational goal in the develop

262 Therapists may focus on increasing meaningful social interactions, addressing concerns rela

263 There are meaningful sociodemographic disparities in access and ou

264 iplinary approaches to evaluate and identify meaningful solutions to these global challenges.

265 it is critical to demix the recordings into meaningful spatial and temporal components that can be m

266 , scales, and cadences, but to also identify meaningful spatial patterns in these data, especially in

267 allenges associated with making test results meaningful, specifically considering the complex relatio

268 and partial AUC for the region of clinically meaningful specificity (85%-100%) were used to compare t

269 e SEE program participants showed clinically meaningful, statistically significant improvement in gla

270 climate change scenario is a sustainable and meaningful strategy.

271 t for the use of machine learning to extract meaningful structural information from complex physical

272 health system, EHRs must contain clinically meaningful structured data elements that can be readily

273 nctional connectivity networks to clinically meaningful subjective states.

274 counts and can be used to cluster cells into meaningful subpopulations.

275 ly and to classify samples into biologically meaningful subtypes defined by tumor mutational burden.

276 in a higher remission rate and a clinically meaningful survival extension in these patients with dif

277 Our study paves the way for meaningful targeted therapeutics for Becker MD and for c

278 n measurement among assays and the lack of a meaningful threshold for TMB classification.

279 o explain the way the device works "in terms meaningful to a general reader struggling with the dilem

280 rowth- and development-related traits, it is meaningful to base SNP-heritability estimation on longit

281 hat both OS and CS assay remained clinically meaningful to distinguish hemophilic from nonhemophilic

282 Cell Biology Mid-career Award is incredibly meaningful to me, as it validates that someone focusing

283 Intraoperative HSI is feasible and meaningful to predict DGF in renal allografts.

284 what level of change in CA19-9 constitutes a meaningful treatment response.

285 convolution (RAD) to deconvolve biologically meaningful tumor populations from multiple transcriptomi

286 ney quality, IRD terminology as a barrier to meaningful understanding, and variable reactions to a 1:

287 and social difficulties suggest these may be meaningful variables to target in the development of int

288 od cell trait GWAS to interrogate clinically meaningful variants across a wide allelic spectrum of hu

289 ations in neural activity drive behaviorally meaningful variations in the likelihood function.

290 ught to test whether microtubules contribute meaningful viscoelastic resistance to diastolic stretch

291 Molecular interaction maps have emerged as a meaningful way of representing biological mechanisms in

292 rly among "locally adapted" breeds, is not a meaningful way to characterize goat populations.

293 sms that underlie the ability to behave in a meaningful way to the same stimulus.

294 and competitive context in a quantitatively meaningful way, implicating a competitive strategy that

295 and difficult to interpret in a biologically meaningful way.

296 ter- and preictal periods in a statistically meaningful way.

297 sequencing can be applied to scRNA-seq in a meaningful way.

298 anding the conformational space sampled in a meaningful way.

299 ism and immune metabolism in therapeutically meaningful ways.

300 undergoing prostatectomy reported clinically meaningful worse incontinence through 5 years compared w