ライフサイエンスコーパス: mechanical stress

1 rve the shape of tissues under conditions of mechanical stress.

2 membrane, resulting in abnormal response to mechanical stress.

3 sion over time and recovery after changes in mechanical stress.

4 sis by isotropic and anisotropic response to mechanical stress.

5 xed state but is enriched in the presence of mechanical stress.

6 py, and impaired intercellular adhesion upon mechanical stress.

7 mMLCK is suspected to be also regulatable by mechanical stress.

8 observed in metallic glasses deforming under mechanical stress.

9 widespread mechanism to sense and respond to mechanical stress.

10 lead to the reinforcement of leaves against mechanical stress.

11 re cannot be measured independently from the mechanical stress.

12 c rods and consider its response to external mechanical stress.

13 e leaflet and commonly to areas of increased mechanical stress.

14 lead to the accrual of plaque-destabilizing mechanical stress.

15 ct, particularly when cells are subjected to mechanical stress.

16 of the spectrin tetramers to release excess mechanical stress.

17 tiation is critical for cambial growth under mechanical stress.

18 flight muscle activation is also produced by mechanical stress.

19 els might play a neuroprotective role during mechanical stress.

20 apable of generating non-uniform patterns of mechanical stress.

21 ermed pili are necessary for adherence under mechanical stress.

22 oglial function, regulation, and response to mechanical stress.

23 ult, the disulfide bond is under substantial mechanical stress.

24 nic joint inflammation, which is worsened by mechanical stress.

25 d in a nonphotomagnetic compound by applying mechanical stress.

26 low set up, as well as when subjecting it to mechanical stress.

27 ent stem cell colonies and spatially present mechanical stress.

28 nsitive ion channels may sense the resulting mechanical stress.

29 entially in cells located in regions of high mechanical stress.

30 CTCs can be released through locally applied mechanical stress.

31 able top and bottom electrode to relieve the mechanical stress.

32 nsparency while keeping high stability under mechanical stress.

33 low applied electric field (<0.2 MV/m) under mechanical stress.

34 e been suggested to be directly sensitive to mechanical stress.

35 furrow accumulation, acting in parallel with mechanical stress.

36 /VASP proteins to reinforce the cell against mechanical stress.

37 hole connector both in equilibrium and under mechanical stress.

38 teoblasts respond to different magnitudes of mechanical stress.

39 ea of the skin that undergoes high levels of mechanical stress.

40 xpressing cells is their routine exposure to mechanical stress.

41 materials that are also optimized to resist mechanical stress.

42 emperature, metal ions, redox potential, and mechanical stress.

43 pathogenesis owing to conserved responses to mechanical stress.

44 their protection mechanisms against external mechanical stress.

45 l area to limit larger cell elongation under mechanical stress.

46 n low-pressure vessels subjected to cyclical mechanical stress.

47 w force and remain covalently attached under mechanical stress.

48 r displacements and rotations in response to mechanical stress.

49 that link tissue cells experiencing intense mechanical stress.

50 l for understanding structural changes under mechanical stress.

51 the increase in membrane tension induced by mechanical stress.

52 gnment and a higher rate of detachment under mechanical stress.

53 th an actomyosin-dependent increase in local mechanical stress.

54 L) mechanism is favored for Fg-binding under mechanical stress.

55 when cell growth responds to the tissue-wide mechanical stresses.

56 ty of the cell to external environmental and mechanical stresses.

57 ear deformation in response to physiological mechanical stresses.

58 , and defect size can further increase under mechanical stresses.

59 sful environment and subjected to continuous mechanical stresses.

60 city enables the microtubules' adaptation to mechanical stresses.

61 red biophysical metrics associated with cell mechanical stresses.

62 ly by opposing large turgor pressure derived mechanical stresses.

63 m is built must sustain different degrees of mechanical stresses.

64 tural integrity despite being under constant mechanical stress [4].

65 he collective generation and transmission of mechanical stresses across cell monolayers.

66 Here, we show that mechanical stress activates Pkc1, which prevents lysis o

67 ts showed that variations of temperature and mechanical stress affect the toxicological impact of tir

68 s accumulation, relief and redistribution of mechanical stress along the protein/DNA meshwork of meio

69 In addition to signaling pathways, mechanical stresses also direct cytoskeletal protein acc

70 ork (TM) tissue in the eye is under constant mechanical stress and continuous remodeling of ECM is cr

71 ell as nanodevices and sensors for measuring mechanical stress and damage in situ.

72 that it offers excellent resilience against mechanical stress and deformation, making it a promising

73 issue constructs were subjected to different mechanical stress and electric pacing conditions.

74 The piezoelectrochemical coupling between mechanical stress and electrochemical potential is explo

75 orylatable Ste5 undergo increased lysis upon mechanical stress and exhibit defects in cell-cell fusio

76 role in the ability of cells to both resist mechanical stress and generate force, but the precise in

77 However, how AJs adapt to mechanical stress and how this adaptation contributes to

78 in the absence of AMPK, cells generate more mechanical stress and increase fibronectin fibrillogenes

79 folds that mimic native architecture, resist mechanical stress and induce angiogenesis.

80 Although mechanical stress and injury are important factors, it i

81 ble in vitro model to examine the effects of mechanical stress and interstitial flow on biodegradable

82 differential expression of genes related to mechanical stress and jasmonate biosynthesis/signaling d

83 nction of caveolae, cell-cell adhesion under mechanical stress and lipid transport.

84 as well as the role of hPDLFs in monitoring mechanical stress and maintaining tissue homeostasis dur

85 Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of the beating h

86 ir color-based response can readily describe mechanical stress and phase transition phenomena.

87 bination to protect axons and dendrites from mechanical stress and propose that defects in beta-spect

88 g and thin yet must withstand high levels of mechanical stress and proteolytic attack.

89 nctions autonomously to mediate responses to mechanical stress and provide in vivo evidence for a rol

90 ulnerability of hypertrophic chondrocytes to mechanical stress and showed that SOC protects these cel

91 enesis, are largely controlled by changes in mechanical stress and tension at the cell surface.

92 relationship between endogenous patterns of mechanical stress and the generation of bioelectric grad

93 fibrosus (AF) caused by ageing or excessive mechanical stress and the resulting prolapse of the nucl

94 tant mechanism by which atrial cells measure mechanical stress and translate it to alter their excita

95 ading on articular cartilage induces various mechanical stresses and strains.

96 It demonstrates a generic crosstalk between mechanical stresses and the key players of cell cycle re

97 While it is accepted that mechanical stresses and the mechanical properties of ECs

98 within the walls of arteries is regulated by mechanical stresses and vasoactive signals.

99 al factors, including temperature, humidity, mechanical stress, and chemical stimuli such as odorants

100 environmental factors including temperature, mechanical stress, and food availability.

101 n isolated vessels, BPIFB4 is upregulated by mechanical stress, and its knock-down inhibits endotheli

102 en exposed to moisture, oxygen, heat, light, mechanical stress, and reverse bias.

103 anges of thermal conductivity are induced by mechanical stress, and the corresponding device is a key

104 External mechanical stress appears to make growth more homogeneou

105 Two cellular responses to mechanical stress are a microtubule cytoskeletal respons

106 polymers that release small molecules under mechanical stress are appealing targets for applications

107 re have shown that in tachypacing-induced HF mechanical stresses are associated with both structural

108 Chronic neurohormonal and mechanical stresses are central features of heart diseas

109 Mechanical stresses are tensorial in nature, and thus pr

110 Biofilms buildup internal mechanical stress as single cells grow within the elasti

111 iferation are templated by both gradients of mechanical stress as well as by gradients in membrane vo

112 anization and allows for compensation of the mechanical stress associated with oogenesis by conferrin

113 m a global inhibition of protein dynamics by mechanical-stress-associated changes in the cytoskeletal

114 d with membrane remodeling and controlled by mechanical stress at these sites is unclear.

115 ding mechanisms such as tissue buckling from mechanical stress, axon tethering, localized proliferati

116 hence, cell growth is observed to respond to mechanical stresses building up within a tissue.

117 ies contribute through their ability to bear mechanical stress, but experimental measures of their re

118 oirs facilitate cell shape change and buffer mechanical stress, but we do not know how reservoir dyna

119 ng experimental support for the induction of mechanical stress by differential growth, and a molecula

120 removal of material in locations of high/low mechanical stress by utilizing local resources guided by

121 ntramolecular collapse in order to show that mechanical stress can be removed from the polymer backbo

122 Mechanical stress can drive chemical reactions and is un

123 Mechanical stress can influence cell proliferation in vi

124 Pathological mechanical stress can lead to maladaptive cellular respo

125 Conversely, mechanical stress can provide a regulatory feedback sign

126 rovide insight into how binding partners and mechanical stress can regulate the conformation of full-

127 l cell power output and the associated chemo-mechanical stresses can also lead to catastrophic fractu

128 s of the inner ear are exposed to continuous mechanical stress, causing damage over time.

129 When subjected to mechanical stress, cells lost their initial orientation

130 rendered the skin vulnerable to injury under mechanical stress conditions.

131 tonia, though the extent to which endogenous mechanical stresses contribute to these pathologies is u

132 protocol also diminished thermal effects and mechanical stress created during nanosecond laser ablati

133 onal views suggest that, under conditions of mechanical stress, cytokines, growth factors, and neuroh

134 cultured keratinocytes both to PV IgG and to mechanical stress, demonstrating that splitting at the b

135 In the 2D model, mechanical stress-dependent actin breakdown is shown to

136 The response to mechanical stress depends strongly on the forces experie

137 Mechanical stresses directly regulate the function of se

138 Even repeated mechanical stress does not result in the delamination of

139 Mechanical stress due to pressure and volume overload an

140 a drug within a capsule, without thermal or mechanical stress during manufacture.

141 ron and ion transport and help withstand the mechanical stress during the repeated electrochemical cy

142 tigated spontaneous and induced release with mechanical stress during/after simulated sunlight and ra

143 ked how fast and how far localized pulses of mechanical stress dynamically propagate through biologic

144 the hypertrophic chondrocytes from the high mechanical stress encountered in the terrestrial environ

145 internally generated and externally imposed mechanical stresses, endowing the cell with the ability

146 igations of the crosstalk between an organ's mechanical stress environment and biochemical signaling

147 If the mechanical stress environment in the tissue is altered t

148 present a method to quantify cell-generated mechanical stresses exerted locally within living embryo

149 toskeleton protects axons and dendrites from mechanical stress, exploiting mutations in UNC-70 beta-s

150 tory of benign prostatic hyperplasia creates mechanical stress fields in the prostate that impede pro

151 The mechanical stress fields that originate as tumors enlarg

152 n prostatic hyperplasia contributes to these mechanical stress fields, hence further restraining pros

153 ll adhesion adherens junctions that transmit mechanical stress from cell to cell.

154 We hypothesized that altered mechanical stress from mastication contributes to period

155 y accounts for the interplay between growth, mechanical stress from the motile species, and friction

156 Subsequently, exerting mechanical stresses further enhances the molecular align

157 We observed that the mechanical stress gradients in the tissues presaged grad

158 M NaCl and 50 mM sorbitol without subsequent mechanical stress had considerable impact on total pheno

159 nction of proteins within the cell envelope, mechanical stress has the potential to regulate multiple

160 Under frequent mechanical stress, hMSCs grown on our hydrogel substrate

161 insights into mechanisms that could control mechanical stress homeostasis in dynamic epithelial tiss

162 onal diversity under physiological levels of mechanical stress, however, is poorly understood.

163 cbEGF domain calcium binding decreases under mechanical stress (i.e. cbEGF domains are mechanosensiti

164 ere, we investigate the role of temperature, mechanical stress (i.e., turbulence), UV, and CO(2) on t

165 acellular transport pathways by LECs and how mechanical stress (ie, fluid flow conditioning) alters e

166 tation, caloric restriction, osmotic stress, mechanical stress, immune response, and even emotional s

167 membrane flexibility and stability to limit mechanical stress imposed on the ER membrane.

168 The role of mechanical stress in 'overuse' injuries, such as tendino

169 psid disruption happened at lower thermal or mechanical stress in Ad5-VII- compared to wild-type (Ad5

170 in TRPC3-mediated RhoA activation induced by mechanical stress in cardiomyocytes and transforming gro

171 te zyxin regulates cytoskeletal responses to mechanical stress in culture.

172 s epithelial cells and in response to cyclic mechanical stress in human Schlemm's canal endothelial c

173 eta1 and phospho-Smad2/3 were not induced by mechanical stress in nonfibrotic lungs.

174 ement of cardiac efficiency and reduction of mechanical stress in patients with systolic dysfunction.

175 The detection of mechanical stress in polymeric materials through optical

176 Here we manipulate tensile and shear mechanical stress in the bacterial cell envelope and use

177 ocytes (PC-1 knockout) and subjected them to mechanical stress in vivo (transverse aortic constrictio

178 ility and couples biochemical responses with mechanical stresses in cells, only recently have we begu

179 ally asymmetric environment with non-uniform mechanical stresses in radial and circumferential direct

180 the nuclear envelope may balance significant mechanical stresses in yeast and in cells from higher or

181 tissue, and biochemical evidence of chronic mechanical stress, including increased angiotensin II ty

182 lso found in other tissues known to be under mechanical stress, including stress fibers in migratory

183 l suspensions can propagate and absorb large mechanical stresses, including impacts and shocks.

184 e and reduced ability of the BM to withstand mechanical stress indicate that PBA may be counter-indic

185 Vasoconstrictors and mechanical stress induce remodelling of the focal adhesi

186 bilize the microtubules against the repeated mechanical stress induced by ciliary motility.

187 However, the mechanisms governing mechanical stress-induced activation of L-type calcium c

188 We hypothesized that mechanical stress-induced enhancement of CD44-intracellu

189 timal actin-binding affinity that allows for mechanical stress-induced protein accumulation.

190 the maintenance of bone mass, whereas excess mechanical stress induces bone resorption.

191 We found that mechanical stress induces supercoils and plectonemes in

192 included effects on lung hyperinflation and mechanical stress, inflammation, excessive mucus product

193 how the coupling between vibronic states and mechanical stresses inherent to conjugated polymers can

194 Furthermore, mechanical stress inhibits Dll4 expression and leader ce

195 rticle or cellular aggregate, likely induces mechanical stress initiated on the luminal side of the E

196 accommodation of electrochemically generated mechanical stress inside the lithium: this stress can be

197 Similarly, caveolae transduce mechanical stress into PM lipid alterations that, in tur

198 ely 20 nm, and manifests itself clearly when mechanical stress is applied to the membrane.

199 s anisotropy and heterogeneity depend on how mechanical stress is applied.

200 It is well known that adequate mechanical stress is essential for the maintenance of bo

201 ch as tendinopathy, has long been known, but mechanical stress is now also emerging as a possible tri

202 Mechanical stress is pervasive in egress routes of malig

203 , unlike heat- or pressure-driven reactions, mechanical stress is rarely applied isometrically, obscu

204 tin, but how the genome is protected against mechanical stress is unclear.

205 How materials behave when subjected to mechanical stresses is studied by mechanics of materials

206 ltrastructure that allows axons to withstand mechanical stress, is poorly understood.

207 with two roots can better withstand stronger mechanical stresses like those resulting from tooth occl

208 Excessive mechanical stress loading promoted the de-differentiatio

209 ng impact on the cell membrane's tenacity to mechanical stress, making cells strongly prone to ruptur

210 ry of a vascular EC barrier after pathologic mechanical stress may be accelerated by cell exposure to

211 erphase cell is influenced by cell adhesion, mechanical stress, neighbour topology, and planar polari

212 Plant cells in tissues experience mechanical stress not only as a result of high turgor, b

213 ensuring that both organs can withstand the mechanical stress of embryo elongation; mistiming of epi

214 fically, the MoS2 films are able to generate mechanical stresses of about 17 megapascals-higher than

215 oxygen evolution reaction (OER) by applying mechanical stress on a highly n-type doped rutile TiO(2)

216 chanical tool capable of applying controlled mechanical stress on an individual cell and simultaneous

217 this damage is not due to DNA breakage from mechanical stress on chromatin in the deformed nucleus.

218 We here show that mechanical stress on collagen produces radicals and subs

219 Mechanical stress on eukaryotic nucleus has been implica

220 function and accumulations of GAGs increase mechanical stress on nearby elastic lamellae, thereby in

221 al encounters a target, it expands, imposing mechanical stress on the wire and altering its magnetic

222 cifically focuses on impacts of LVAD-related mechanical stress on VWF structural stability and adhesi

223 e imposes very harsh chemical, physical, and mechanical stresses on biospecimens, significantly compr

224 es of material fatigue, the concentration of mechanical stresses on pre-existing defects in the micro

225 better understanding of the role of dynamic mechanical stresses on the fate of hMSCs but also for th

226 Even minor external mechanical stress or thermal expansion can result in mem

227 turing of outer oxide-acetate layers through mechanical stressing or shearing, thus initiating a casc

228 Local alignment of cell velocity and mechanical stress orientation-a phenomenon dubbed "plith

229 Experimental perturbation of mechanical stress pattern further supported a contributi

230 onse of osteoblasts to varying magnitudes of mechanical stress play a key role in switching the mode

231 It is well known that mechanical stress plays a major role in tissue remodelin

232 entified an amplification mechanism in which mechanical stress promotes the microtubule response to s

233 s of the fiber direction are introduced, the mechanical stress provides a robust directional cue for

234 ensitivity of the integrin bond, we identify mechanical stress, rather than mechanical load, as a per

235 tal and theoretical approaches and show that mechanical stresses regulate bacterial cell wall growth.

236 Mechanical stress regulates development by modulating ce

237 force, and the anatomical extent of several mechanical stress-related disorders in tendons and ligam

238 These findings demonstrate that mechanical (stress relaxation) and chemical (hypoxia) pr

239 observed when both the supercoiling and the mechanical stress release due to gyrase are present in t

240 DNA and dsRNA in sequence contexts and under mechanical stresses relevant to their biology.

241 ternal mechanical strain, how HDs respond to mechanical stress remains poorly understood.

242 where filaments are interconnected and under mechanical stress, remains unclear.

243 dly promotes epithelial damage and decreased mechanical stress resistance of the skin before inductio

244 hat the opening dynamics are dictated by the mechanical stress response of the cell wall matrix, and

245 ng and focal adhesion formation and causes a mechanical stress response, concomitant with activation

246 anism induced by angiotensin II (Ang II) and mechanical stress, showed a remarkable similarity betwee

247 In this study, we report that mechanical stress specifically induces varicosities in t

248 oteins, those that accumulate in response to mechanical stress, specifically nonmuscle myosin IIA (MY

249 e full cell shows unprecedented tolerance to mechanical stress such as bending and cutting, where it

250 stitute a membrane reservoir that can buffer mechanical stresses such as stretching or osmotic swelli

251 to operate in microgravity and to withstand mechanical stress, such as take-off vibrations, and onbo

252 roteinuric rats, and in podocytes undergoing mechanical stress suggests that this protein has a role

253 igh echogenicity in HFU images and the large mechanical stress that exceeded the yield strength.

254 ive pressure ventilation exposes the lung to mechanical stresses that can exacerbate injury.

255 ng tissues, particularly when growth induces mechanical stresses that can in turn affect growth rates

256 id (HA), collagen and the spatial origins of mechanical stresses that close off blood vessels was inv

257 cate that closure of the tunnel is driven by mechanical stresses that develop within a cross-linked a

258 Cytoskeletal actin assemblies transmit mechanical stresses that molecular sensors transduce int

259 ical levels of force represent a biological (mechanical) stress that elicits an immune system-mediate

260 Our study reveals that under mechanical stress the regulation of mechanoprotection by

261 To adapt to the dynamic change in mechanical stress, the constitutive individual proteins

262 heart is subject to continuous metabolic and mechanical stress, the proteasome plays a particularly i

263 s most commonly observed at sites of maximal mechanical stress: the leaflet tips and the commissures.

264 yosin assemblies to adapt dynamically to the mechanical stresses they convey and direct their own rem

265 At high ethidium concentrations and elevated mechanical stress, this causes an almost complete occupa

266 ng distances directly by the transmission of mechanical stress through the DNA itself, without any re

267 valent macromolecules tend to fragment under mechanical stress through the mechanochemical scission o

268 e pathway that regulates tissue responses to mechanical stress through the polarization of actomyosin

269 When applying mechanical stress to a bulk metallic glass it responds w

270 lular matrix by MMP14, thereby releasing the mechanical stress to allow for its healthy expansion.

271 V. cholerae biofilms can generate sufficient mechanical stress to deform and even disrupt soft epithe

272 Ball-milling utilizes mechanical stress to modify properties of carbon nanotub

273 Experiments use thermal, chemical, or mechanical stress to perturb the folding equilibrium for

274 ls on the damaged areas from the increase in mechanical stress to prevent/mitigate failure.

275 a nonconjugated to a conjugated state under mechanical stress to significantly change their properti

276 owing application of an external vibrational mechanical stress to that tissue.

277 y (3D-MTC) is a technique for applying local mechanical stresses to living cells.

278 is the mechanotransduction pathway by which mechanical stress transduced by the microtubule network

279 Cardiovascular mechanical stresses trigger physiological and pathologic

280 These results uncover a mechanical stress-triggered crosstalk mechanism modulati

281 also reproduces quantitative assessments of mechanical stress using laser dissection and failures of

282 ofluidic constrictions, and we calibrate the mechanical stresses using gel beads.

283 eletal proteins during cytokinesis and under mechanical stress, using fluorescence recovery after pho

284 h stabilizes long-lived microtubules against mechanical stress via acetylation and has been implicate

285 Cells generate mechanical stresses via the action of myosin motors on t

286 We present an active, purely mechanical stress wave isolator that consists of short c

287 skin barrier functions (immune suppression, mechanical stress), we studied the possible role of FLG

288 ting the response of this modular protein to mechanical stress, we studied its force-induced unfoldin

289 atent and can be triggered by applying local mechanical stress, whereby crystals leap several centime

290 n-uniform growth can lead to accumulation of mechanical stress, which in the context of two-dimension

291 ch assays, but after subjecting the cells to mechanical stress, which is normally present in wounds,

292 Thus, club cells detect junction damage as mechanical stress, which signals danger via TRPV4, calci

293 est that transcarbamoylation is activated by mechanical stress, which we attribute, on the basis of D

294 breakable bonds were available to dissipate mechanical stresses while leaving the surrounding matrix

295 by this scenario, the continuous presence of mechanical stress within the chromosome axes could poten

296 ere we demonstrate that the application of a mechanical stress within the elastic regime breaks this

297 hematical modeling revealed that SOC reduces mechanical stress within the growth plate.

298 t the onset of MET correlates with a peak in mechanical stress within the HFR and changes in HPC migr

299 he bioelectric gradient formed downstream of mechanical stresses within the tissues and depended on c

300 to extensive deformations, yet sustain such mechanical stress without damage.