ライフサイエンスコーパス: mechanically

1 ecome indefinite when matter behaves quantum mechanically.

2 res representative of nearly every family of mechanically activated channel described so far have und

3 the contribution of Piezo2, a low-threshold mechanically activated channel, to acute ocular pain, we

4 we demonstrate functional expression of two mechanically activated channels in human TM cells.

5 We describe here the presence of mechanically activated currents in melanoma cells that a

6 direct evidence that Piezo2 channels support mechanically activated currents of different kinetics in

7 nosensitivity, is sufficient to reconstitute mechanically activated currents.

8 rapidly, intermediately and slowly adapting mechanically activated currents.

9 The resulting poly(BCH-Naph)s can be mechanically activated into conjugated polymers using ul

10 es in the physiology and structures of known mechanically activated ion channel families and discuss

11 olecular scale, these forces are detected by mechanically activated ion channels, which constitute th

12 muli into electrical or chemical signals via mechanically activated ion channels.

13 e converted into electro-chemical signals by mechanically activated ion channels.

14 the JCI, Swain et al. describe roles for the mechanically activated plasma membrane calcium channels

15 Although stimulation of the mechanically activated, calcium-permeable ion channel Pi

16 nistic data demonstrating disruption of this mechanically-activated calcium pathway in breast cancer

17 Piezo1 and Piezo2 belong to a family of mechanically-activated ion channels implicated in a wide

18 ase was obtained by exothermic combustion of mechanically-activated nanostructured metallic precursor

19 ropose a role for Piezo1 channels, which are mechanically-activated non-selective cation channels.

20 up by diverting tensional forces away from a mechanically active functional group embedded in one of

21 to physically connect a number of artificial mechanically active molecular units such as photochromic

22 n somatic length changes that are thought to mechanically amplify sound-evoked vibrations.

23 In this work, we prepare mechanically and biologically skin-like materials (PSeD-

24 id space to accommodate volume changes and a mechanically and dimensionally stable outer surface.

25 he membranes are used for the fabrication of mechanically and electrically actuated camouflage device

26 The films are mechanically and electrically robust, with a breakdown s

27 retchable interconnects that heal the damage mechanically and electrically.

28 his study, we report on the realization of a mechanically and electronically robust graphene-based mo

29 2D materials that are weakly connected both mechanically and electronically.

30 interface with the skin in a manner that is mechanically and thermally imperceptible.

31 When the electrodes were subjected to mechanically-applied tensile strain, the amount of hydro

32 This mechanically assisted bioluminescence proceeds through a

33 RT OFF had a higher Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) me

34 were more commonly Interagency Registry for Mechanically Assisted Circulatory Support profile 1 (30.

35 Among Interagency Registry for Mechanically Assisted Circulatory Support profile 1 pati

36 year compared with Interagency Registry for Mechanically Assisted Circulatory Support profile 1 pati

37 ult patients in the Interagency Registry for Mechanically Assisted Circulatory Support requiring dura

38 ult patients in the Interagency Registry for Mechanically Assisted Circulatory Support with dilated c

39 y of (1) INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) RHF classific

40 INTERMACS registry (Interagency Registry for Mechanically Assisted Circulatory Support) who received

41 irculatory Support, Interagency Registry for Mechanically Assisted Circulatory Support, Kormos, Pitts

42 outcomes using the Interagency Registry for Mechanically Assisted Circulatory Support.

43 to the study of surface interactions and to mechanically bound species.

44 causes of 1-year mortality in medically and mechanically bridged patients, and to evaluate differenc

45 s the plasma membrane and protects the cells mechanically by opposing large turgor pressure derived m

46 It often follows mechanically challenging foods whether eaten often or ra

47 phase of the gape cycle and while processing mechanically challenging foods.

48 N, suggesting that TIM-EBOV interactions are mechanically comparable to previously reported adhesion

49 Using an AFM cantilever tip, mechanically compliant acicular microcrystals of three N

50 bands extended into a large-scale network of mechanically connected cells, in which the connected cel

51 d single-stacking thiophene junctions by the mechanically controllable break junction (MCBJ) techniqu

52 steric indicator displacement assay (AIDAs), mechanically controlled indicator displacement assays (M

53 e complex during the collective migration of mechanically coupled cells because of the additional reg

54 Deformation is mechanically coupled from the crust to the asthenosphere

55 We derived a tissue-scale, patient-specific mechanically coupled mathematical model to qualitatively

56 Mechanically coupled proton transduction offers potentia

57 By extending our previous in vivo mechanically-coupled reaction-diffusion modeling framewo

58 We developed a technique of mechanically coupling two active hair bundles, enabling

59 gh the narrow microcapillary may squeeze and mechanically damage the cells which threaten the cell vi

60 n at the ELIMAKI locus (EKI), which causes a mechanically defective response to weight stimulus resul

61 Epithelial tissues mechanically deform the surrounding extracellular matrix

62 Soft, mechanically deformable materials and systems that can,

63 rally occurring dielectrics whereby they are mechanically deformed under the application of an electr

64 ctical means of controlling equilibration by mechanically deforming their samples.

65 ng and reference membranes are held in place mechanically, delamination of these membranes from the u

66 laser annealing may allow the use of PDA in mechanically demanding applications previously considere

67 However, their diets are diverse and often mechanically demanding, and as such, their teeth should

68 , the impact of such tissues in the complex, mechanically demanding, and highly dynamic valvular syst

69 s and canine kidney epithelial MDCK II cells mechanically destabilizes the acinus.

70 ored in all patients; the esophagus was also mechanically deviated in 10 patients.

71 ells interact with each other in response to mechanically differential substrates would allow an incr

72 sensors), when loaded, medaka bones model in mechanically directed ways, successfully reducing high t

73 eaves and stems to study the reunion between mechanically disconnected tissues.

74 veral micrometres in length or width), which mechanically disrupts the endosomal membrane and directl

75 lity of Grubbs catalyst to catalyze multiple mechanically distinct cascade reactions in a chemoselect

76 oring the dynamics of spindle orientation in mechanically distinct regions of the fly notum, we find

77 s in eki compared with WT, along with a more mechanically elastic cambial zone and radial compression

78 orneal neurons displaying the three types of mechanically evoked currents is similar to the wild type

79 emical perturbation experiments suggest that mechanically evoked responses require the influx of extr

80 critical for normal mechanotransduction and mechanically-evoked behavioral responses in mice.

81 Here we show that mechanically exfoliated graphene and hexagonal boron nit

82 pic third-harmonic generation (THG) from the mechanically exfoliated thin GeAs flakes is reported.

83 r vdW metals, and demonstrate that it can be mechanically exfoliated to the two-dimensional (2D) limi

84 is study aimed to evaluate the shelf-life of mechanically filleted well-fed Atlantic mackerel during

85 he human body, these devices also need to be mechanically flexible and stretchable, thus posing a sig

86 ectly grown on epitaxial substrates, and are mechanically flexible depending on the thickness.

87 as edge computing, resistive switching, and mechanically flexible sensing and electronics.

88 As OLEDs can be fabricated on mechanically flexible substrates and structured into arr

89 ly conductive fillers have been developed as mechanically flexible, easily processable electromagneti

90 r-based electronics enabling lightweight and mechanically flexible/stretchable functions are desirabl

91 ckets' that house highly water-repellent and mechanically fragile nanostructures.

92 Perception of sound is initiated by mechanically gated ion channels at the tips of stereocil

93 aring, and blood pressure regulation require mechanically gated ion channels that convert mechanical

94 in in TMIE with similarity to those in other mechanically gated ion channels.

95 Similar to mechanically gated TREK channels, the C-terminal cytopla

96 he optoelectronic and physical properties of mechanically generated conjugated polymers.

97 (LIG) are reported and their applications in mechanically guided 3D assembly and human-soft actuators

98 ar mechanotransduction and as a regulator of mechanically guided cell migration.

99 Finally, inhibition of PKA activity inhibits mechanically guided migration, also known as durotaxis.

100 Mechanically guided, 3D assembly has attracted broad int

101 similar to KIF3AC, suggesting the homodimers mechanically impact each other's motility to reproduce t

102 isms for the understanding of root growth in mechanically impeding soil conditions and provides insig

103 eir translocation activity is utilized chemo-mechanically in DNA unwinding is poorly understood.

104 However, invadopodia can function mechanically, independent of their degradative activity,

105 (PLXND1) has a role in mechanosensation and mechanically induced disease pathogenesis.

106 This mechanically induced DNA damage could not only increase

107 Thus, we have uncovered a new mechanism for mechanically induced DNA damage, linking mechanical defo

108 he pore network and the naturally present or mechanically induced fracture network together determine

109 oal was to identify ion channels involved in mechanically induced myotonia and to evaluate block of t

110 Elimination of mechanically induced myotonia by TRPV4 inhibition offers

111 The suppression of mechanically induced myotonia occurred without altering

112 developed a novel system to enable study of mechanically induced myotonia using both genetic and pha

113 Mechanically induced myotonia was markedly suppressed in

114 lectrically induced myotonia) or percussion (mechanically induced myotonia).

115 chanisms triggering electrically induced and mechanically induced myotonia.

116 cer patients often have severe, chronic, and mechanically induced pain at the site of the primary can

117 spersal of Ste5 from mating projections upon mechanically induced stress and during cell-cell fusion,

118 slated into accelerated blistering following mechanically induced stress.

119 ynyl)pentacene (TIPS-P) crystals can undergo mechanically induced structural transitions to exhibit s

120 es experience increased strain, resulting in mechanically induced trophic signaling and eventually di

121 te that water plays an important role in the mechanically induced unfolding of biomolecules.

122 Our results indicate that upon mechanically induced unfolding of the protein, the solve

123 dentification that oncogenic KRas suppresses mechanically-induced calcium at the level of ROS provide

124 evices require reliable nanocomponents where mechanically-induced irreversible structural damage shou

125 Intact, PG-depleted, and mechanically injured + PG-depleted cartilage samples (n

126 ce potently inhibited axonal regeneration of mechanically injured cerebral cortex neurons from mice.

127 idopsis thaliana, profiles were obtained for mechanically inoculated rosette leaves and systemically

128 h all components of the cytoplasm comprise a mechanically integrated aster gel that moves collectivel

129 cally incongruent actions are represented as mechanically interdependent contributions to a joint act

130 We now show that mechanically interlocked catalytic rings can effectively

131 a highly efficient method for constructing a mechanically interlocked molecule in unprecedented near

132 Sophisticated mechanically interlocked molecules (MIMs) with interesti

133 Mechanically interlocked molecules are likely candidates

134 scinating candidates for the design of novel mechanically interlocked molecules with new properties.

135 novel photoresponsive molecular switches and mechanically interlocked molecules.

136 rochemical characterization of the different mechanically interlocked nanographenes evidence enhanced

137 Herein, we report the synthesis of mechanically interlocked nitrogenated nanographenes.

138 show that this approach can be combined with mechanically interlocking molecules to produce nanocapsu

139 dardize methods for producing, maturing, and mechanically interrogating iPSC-derived cardiomyocytes,

140 tension is low, or in regions that have been mechanically isolated from the rest of the tissue via la

141 with the more heterogeneous distribution of mechanically linked filaments displayed by branched netw

142 ially if the movements are, or appear to be, mechanically linked to a more distal joint action goal.

143 pling dynamic system and arrhythmogenesis in mechanically loaded hearts.

144 functional adaptation and specialisation of mechanically loaded tissues using tendon; a simple align

145 By mechanically manipulating MJ0366, a small single domain

146 d the width of the tunneling barriers can be mechanically modulated via the piezotronic effect.

147 In a quantum-mechanically noncommuting theory, nonclassicality manife

148 Our work shows that tumor cells are mechanically plastic to adapt to many environments and r

149 for invasive breast cancer cells cultured in mechanically plastic, nanoporous, and minimally degradab

150 d show that the composites produced are more mechanically pliant than the inorganic glass itself.

151 qubits while imparting the smallest quantum mechanically possible disturbance to the remaining qubit

152 We hypothesized that mechanically pre-conditioning on a soft matrix (soft pri

153 oof-of-concept for a device that can magneto-mechanically prevent the first stage in bacterial biofil

154 r an initial expansion during lithiation but mechanically prevents shrinkage as antimony forms voids

155 The textiles with mechanically processed surfaces (i.e., fleece) released

156 We identified two network properties that mechanically promote robustness.

157 d bridge arrays arise by a single continuous mechanically promoted progression, driven by stress with

158 ible with consumption of hard foods, such as mechanically-protected seeds, but dental microwear analy

159 ed at the tips of thin cellular processes in mechanically quiescent cells.

160 ivation of corneal keratocytes from a native mechanically quiescent state to an activated myofibrobla

161 We discovered that this mechanically quiet period is disrupted in embryos with h

162 tems in which the photo-redox components are mechanically rather than covalently linked.

163 ineering that explores the dynamic nature of mechanically reconfigurable, motile, and explosive cryst

164 ick fingers" problem), and can be applied to mechanically reconfigure organic optical waveguides in o

165 Mechanically reducing left ventricular (LV) workload (LV

166 iR targets in chondrocytes Identification of mechanically regulated miRs that have potential to impac

167 al surface of dividing epithelial cells - is mechanically regulated, relying on a balance of forces b

168 aments (F-actin) and associated proteins are mechanically regulated.

169 A subset of miRs were mechanically-regulated in ex vivo cartilage explants and

170 7 MPa (non-physiological) (1 Hz, 15 min) and mechanically-regulated miRs identified using next genera

171 an enhance partner binding, which we propose mechanically regulates cellular adhesion through alpha-c

172 oarchitecture of fibrillar collagen networks mechanically regulates myofibroblast differentiation of

173 These mechanically reinforced and biologically compatible 3D p

174 Ultrasonication of a 120 kDa BCOE copolymer mechanically remodels the polymer backbone, and subseque

175 nclude that MAPK pathway targeting therapies mechanically reprogram melanoma cells to confer a drug-p

176 y) were observed when animals chewed on more mechanically resistant foods.

177 Fibronectin remodeling is mechanically responsive to contralateral variation morph

178 to develop solid electrolytes that are both mechanically robust and strong against external mechanic

179 for many applications originating from their mechanically robust architectures, low density, and high

180 zation/repolymerization mechanism, providing mechanically robust films that can be easily separated f

181 capsulating nanoparticles of metallic tin in mechanically robust graphene tubes, we show tin anodes w

182 These included a previously reported, mechanically robust intermediate located between helices

183 omposed of soft materials that can allow for mechanically robust maneuvers that are not typically pos

184 particle-fluid systems that ultimately yield mechanically robust materials.

185 mass compact at mitotic exit and promotes a mechanically robust nucleus.

186 Here we report the development of mechanically robust thermoplastic polyurethane fibers an

187 , these findings suggest that harvestmen are mechanically robust to the bodily damage imposed by leg

188 , wafers with high ALG content were not only mechanically robust, but also able to protect a model en

189 We suggest that this transparent, mechanically robust, self-cleaning glass could help to n

190 elastomers to fabricate highly stretchable, mechanically robust, soft multifunctional composites wit

191 ls, revealing that the T cell receptor (TCR) mechanically samples antigens carrying single amino acid

192 ontrast material-enhanced US was achieved by mechanically scanning with a linear imaging probe.

193 DOPr agonists inhibited mechanically sensitive colonic nociceptors.

194 Hearing and balance rely on the capacity of mechanically sensitive hair bundles to transduce vibrati

195 The elimination of CEP83 also activates the mechanically sensitive yes-associated protein (YAP) and

196 port that normal breast epithelial cells are mechanically sensitive, responding to transient mechanic

197 Mechanically separated chicken (MSC) was obtained by two

198 thod for identification and investigation of Mechanically Separated Meat (MSM) samples is presented.

199 Their soft nature allows for mechanically shaping them in the photonic lattice.

200 bent section of the crystal was found to be mechanically softer relative to the straight sections, a

201 Average survival rates of mechanically-sorted larvae were over 90% and were compar

202 Using it as mechanically stable anchorage, we demonstrate the applic

203 The as-prepared crystals are mechanically stable and can be exploited for recyclable

204 Mechanically stable and foldable air cathodes with excep

205 These compact chromatin and create mechanically stable chromosomes.

206 Mechanically stable specific heterodimerization between

207 n within an epithelium provides cells with a mechanically stable substrate upon which localized corti

208 ntal functions simultaneously: it provides a mechanically stable track for molecular motor-based tran

209 diamond structure are highly constrained and mechanically stable, which makes it possible to dry the

210 cts result in single-molecule wires that are mechanically stable, with an average lifetime at room te

211 conductors, and be thermally, chemically and mechanically stable.

212 crystalline, highly flexible, ultralong, and mechanically stable.

213 romote continuous actin bundling to generate mechanically stiff actin super-bundles.

214 d heterogeneous cancer stem cells (CSC) into mechanically stiff and soft subpopulations.

215 on immunogenic challenge, lymph nodes become mechanically stiff as immune cells activate and prolifer

216 that hypertrophic chondrocytes are the least mechanically stiff cells within the growth plate.

217 press Li dendrite growth has been the use of mechanically stiff solid electrolytes(8,9).

218 normal and cancer cells become spherical and mechanically stiffen as they enter mitosis.

219 PKB is sufficient to maintain nuclear Yki in mechanically stimulated cells of the wing pouch even aft

220 tially localize to the actin cytoskeleton in mechanically stimulated cells through their tandem LIM d

221 To study this phenomenon quantitatively, we mechanically stimulated rat cortical neurons by shear st

222 In addition, in vivo Ca(2+) imaging on mechanically stimulated zebrafish LL HCs show that ACh e

223 cup of filter coffee which was subsequently mechanically stirred at three intensities, not stirred a

224 ly and irreversibly bind DNA probes that are mechanically strained over probes at rest.

225 Moreover, the spreading epithelium is mechanically stressed and this stress needs to be releas

226 malian zyxin and fission yeast Pxl1 binds to mechanically stressed F-actin networks but does not asso

227 phila wing, where Yki becomes nuclear in the mechanically stretched cells of the wing pouch during la

228 Mechanically stretching the metallocycle-C(60) junction

229 The ability to create mechanically strong 'cancellous bone-like' printable imp

230 his approach demonstrates the feasibility of mechanically strong and anisotropic organonetworks for m

231 ated domains of both an ion conductive and a mechanically strong polymer have been extensively studie

232 lled release of osteogenic factors, within a mechanically-strong biomaterial combined during manufact

233 The effect can be used to mechanically switch the electronics in the nanoscale wit

234 , fabricated via additive manufacturing, and mechanically tested to determine the suitability of the

235 trix mechanical properties, we generated and mechanically tested wet-spun collagen ACLP composite fib

236 By mechanically tethering the plasma membrane to the cortex

237 from electrical circuits that behave quantum mechanically, that is, circuit quantum electrodynamics(6

238 gene expression, but how the nucleus adapts mechanically to changes in the extracellular environment

239 nes displaying dynamic intersheet bonds that mechanically transform into stable tribolayers.

240 ur work uncovers genetically constrained and mechanically triggered adaptive mechanisms contributing

241 design platform for molecular release via a mechanically triggered cascade reaction.

242 Thus, we show that a mechanically triggered increase in endocytosis regulates

243 Here, we report that the mechanically triggered ring-opening of a [4.2.0]bicycloo

244 bba and U. australis) capture zooplankton in mechanically triggered underwater traps.

245 a bioinspired, low-energy process to produce mechanically tunable biopolymer fibers drawn from aqueou

246 s and three unbinding reaction pathways of a mechanically ultrastable R. champanellensis (Rc) Dockeri

247 Mechanically vented patients and ETA specimens were more

248 nd lung recruitment assessed by a CT scan in mechanically ventilated acute respiratory distress syndr

249 ians on evidence-based processes of care for mechanically ventilated adult patients.

250 ated and four control animals) were sedated, mechanically ventilated and connected to an extracorpore

251 Studies in mechanically ventilated children that compared early wit

252 Critically ill adult mechanically ventilated coronavirus disease 2019 patient

253 Of 49 mechanically ventilated coronavirus disease 2019, 40 und

254 disease occurs frequently in critically ill, mechanically ventilated COVID-19 patients.

255 al IRB approval, we examined a subset of our mechanically ventilated COVID-19 patients.

256 group, randomized clinical trial, with 3,957 mechanically ventilated critically ill adults allocated

257 t atrial pressure is frequently required for mechanically ventilated critically ill patients.

258 Anesthesia controls were mechanically ventilated for 7 h without CPB.

259 llary glycemia were collected in a cohort of mechanically ventilated Guillain-Barre syndrome patients

260 ntrolled trial, we assigned, in a 1:1 ratio, mechanically ventilated ICU patients to a plan of no sed

261 We included mechanically ventilated ICU patients who were given mode

262 Among mechanically ventilated ICU patients, mortality at 90 da

263 endently associated with 90-day mortality in mechanically ventilated participants and predicts mortal

264 Four mechanically ventilated patients (aged 40-75 years) with

265 airway pressure is readily available on all mechanically ventilated patients and all ventilator mode

266 and facilitators to early rehabilitation in mechanically ventilated patients and their relevance to

267 with established cardiovascular disease, and mechanically ventilated patients face the highest mortal

268 The fact that mechanically ventilated patients fail to achieve high le

269 Methods: Mechanically ventilated patients from three sites were e

270 study, one third of coronavirus disease 2019 mechanically ventilated patients have a pulmonary emboli

271 Mechanically ventilated patients monitored with a PiCCO2

272 can be performed at the bedside and used in mechanically ventilated patients to guide positive end-e

273 ion during exercise may improve responses of mechanically ventilated patients to physical therapy.

274 cific location among a diverse population of mechanically ventilated patients with acute respiratory

275 Physical therapy is standard care for mechanically ventilated patients, but there is no eviden

276 In critically ill, mechanically ventilated patients, daily interruption of

277 , 554) kcal/d in spontaneously breathing and mechanically ventilated patients, respectively (P = 0.00

278 , 723) kcal/d in spontaneously breathing and mechanically ventilated patients, respectively (P = 0.94

279 = 0.949).Both in spontaneously breathing and mechanically ventilated patients, the best prediction of

280 ove quadriceps leg strength in a majority of mechanically ventilated patients.

281 gher REE both in spontaneously breathing and mechanically ventilated patients.

282 o reduced in a separate validation cohort of mechanically ventilated patients.

283 cility would increase quadriceps strength in mechanically ventilated patients.

284 by Gram-negative pathogens in intubated and mechanically ventilated patients.

285 l patterns of sleep and wakefulness exist in mechanically ventilated patients.

286 s, separately in spontaneously breathing and mechanically ventilated patients.

287 rupture of alveolar walls and barotrauma in mechanically ventilated patients.

288 airways in intact lungs of anesthetized and mechanically ventilated rabbits, at baseline and followi

289 In mechanically ventilated rabbits, we found that both xeno

290 apnia (PCO2 90-100 mm Hg) was established in mechanically ventilated swine by adjusting the tidal vol

291 sedated (COMFORT Behavior Score 11-16) while mechanically ventilated was assessed.

292 least 18 years old, admitted to an ICU, and mechanically ventilated with an endotracheal tube for lo

293 ts (mean age, 62.2 years; 30.2% women; 81.2% mechanically ventilated) were enrolled.

294 ion with 69% in the intensive care unit, 63% mechanically ventilated, and 42% in severe sepsis or sep

295 This mechanically versatile and nonallergenic paper can gener

296 been able to meet these requirements and are mechanically weak due to their heterogeneously crosslink

297 he major plates to the microplate and of the mechanically weaker mobile belts surrounding Victoria th

298 ell shapes that allow escape behaviors being mechanically weaker than those which do not.

299 than one type of particle is treated quantum mechanically with either density functional theory or wa

300 cellular networks emerge, are controlled and mechanically work still remain elusive.