ライフサイエンスコーパス: mechanics

1 at emerges from local molecular and cellular mechanics.

2 d by fields as varied as zoology and quantum mechanics.

3 sents another potential regulator of cardiac mechanics.

4 to characterize plantar flexor muscle-tendon mechanics.

5 ghtly connected to cytoskeletal dynamics and mechanics.

6 tly accompanied by changes in cell shape and mechanics.

7 irect coupling between quantum and continuum mechanics.

8 relate to the paradigms of classical muscle mechanics.

9 and reveals insights on hillslope transport mechanics.

10 the lungs according to regional parenchymal mechanics.

11 lbow range-of-motion when evaluated by joint mechanics.

12 t is widely used to characterize DNA bending mechanics.

13 nucleosome model with sequence-dependent DNA mechanics.

14 gative pressure but do so through undulatory mechanics.

15 rous composite to understand its fundamental mechanics.

16 sed forces define myocyte ultrastructure and mechanics.

17 correlations, using methods from statistical mechanics.

18 age-related diseases that affect lung tissue mechanics.

19 ilitate development of applications in fluid mechanics.

20 ECM, which in turn mediates all cell-tissue mechanics.

21 from first principles of muscle contractile mechanics.

22 about how efferent activity affects hearing mechanics.

23 by which cells can control their cytoplasmic mechanics.

24 phragmatic electric activity and respiratory mechanics.

25 pting protocols developed for ex vivo muscle mechanics.

26 used it to guide his discovery of celestial mechanics.

27 Furthermore, we show that local DNA mechanics affect transcription through TSS-proximal nucl

28 However, how cellular mechanics affects the instructive signaling pathways con

29 o describe ensemble dynamics via statistical mechanics, allowed better contractility with coarse grai

30 we recorded arterial blood gas, respiratory mechanics, alveolar recruitment, and hemodynamic variabl

31 Although plantar flexor muscle mechanics and Achilles tendon energy storage have been e

32 Lung mechanics and airway responsiveness to methacholine were

33 dependently associated with abnormal cardiac mechanics and an increased risk of cardiovascular events

34 R, was independently associated with cardiac mechanics and cardiovascular events.

35 or activity may alter cortical organization, mechanics and cell shape.

36 We outline the statistical mechanics and computational background behind this resea

37 Molecular mechanics and density functional theory (M06-2X and PBE0

38 A brief overview of the mechanics and dynamics of cavitation in soft matter is p

39 metabolic requirements associated with cell mechanics and ECM remodelling, implicating a reciprocal

40 variational approach that combines continuum mechanics and elasticity with quantum many-body treatmen

41 However, the mechanics and energetic costs associated with the breach

42 ein kinase (MEK-ERK) signaling to alter cell mechanics and enhance mitotic rounding, so that Ras(V12)

43 These data reveal the mechanics and extent of how MHC-II shapes the naive CD4(

44 2, 3, 4) using both stationary state quantum mechanics and first principle molecular dynamics simulat

45 agnetic actuators, we have characterized the mechanics and fluctuations of cells' actomyosin cortex a

46 nted increases in the complexities of tissue mechanics and functions.

47 i allows to model feedbacks between cellular mechanics and gene expression (either in a deterministic

48 ynchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; an

49 using dimensional analysis method from fluid mechanics and hydraulic engineering.

50 While the mechanics and impact of anterograde mitochondrial moveme

51 nces allow for accurate determination of the mechanics and kinetics of the myosin working stroke with

52 xternal expiratory resistances optimize lung mechanics and limit tidal-EFL and tidal atelectasis, wit

53 e demonstrate that they dominate cytoplasmic mechanics and maintain cell viability at large deformati

54 ter cell responses to tumor microenvironment mechanics and may reveal chemotherapeutic targets for ca

55 ains poorly understood as it applies to cell mechanics and mechanosensing.

56 However, how cellular mechanics and metabolism are connected is still poorly u

57 licating a reciprocal crosstalk between cell mechanics and metabolism.

58 to the lack of a comprehensive model of cell mechanics and of physiologically relevant experiments.

59 ts of ensemble theory applied to statistical mechanics and on the mathematical concepts of structural

60 nism based on the interplay between cellular mechanics and primordia patterning that results in self-

61 Lung mechanics and regional aeration and ventilation (electri

62 ovide feedback to the prescribers, learn the mechanics and requirements of an ASP, and complete a pre

63 plemented to justify the evaluation of their mechanics and reveal the underlying physics responsible

64 etry group relating non-relativistic quantum mechanics and special relativity via their "mysteries" i

65 have been thoroughly studied through quantum mechanics and statistical analyses.

66 Low modulus mechanics and the ability to accommodate extreme mechani

67 Quantum mechanics and the general theory of relativity are two p

68 consequences for our understanding of matrix mechanics and the influence of excessive glycation, whic

69 are rich and complex due to their nonlinear mechanics and the presence of nontrivial geometrical eff

70 he impact of these changes on adipose tissue mechanics and their role in metabolic disease is poorly

71 open question is whether the laws of quantum mechanics and thermodynamics allow the existence of a co

72 ically, accurate descriptions of the contact mechanics and various boundary conditions involved in th

73 ates its effectiveness in experimental fluid mechanics and verifies it by simulations, potentially pa

74 monstrate an unexpected dependence on matrix mechanics and water permeation.

75 ound imaging to analyze fascicle contraction mechanics and whole-body energy expenditure across three

76 The associations between eGFR, cardiac mechanics, and cardiovascular events were partly mediate

77 power of AFM nanoindentation to probe tissue mechanics, and delineate the impact of metabolic disease

78 tension of the cell membrane, alters tissue mechanics, and drives a more cancerous phenotype.

79 ntal differences in the activation kinetics, mechanics, and effector responses between CD8+ memory T

80 To probe the interplay between shape, mechanics, and fate, we use mouse embryonic stem cells (

81 does not rely on the universality of quantum mechanics, and it is independent of the interpretation o

82 ce will promote applications in electronics, mechanics, and optics.

83 of electronic structure, quantum statistical mechanics, and quantum dynamics that are of potential in

84 rimental studies of soft materials, flexible mechanics, and system packaging provides key fundamental

85 uce the coding biases inherent in peripheral mechanics, and wind cues are brought into the same circu

86 For continuum mechanics applications, the concept of 'particle' can be

87 ow control strategies in other complex fluid mechanics applications.

88 A computational solid mechanics approach was utilised to determine the extent

89 in presence of water molecules, by a quantum mechanics approach.

90 among prior efforts is the use of continuum mechanics approximations to evaluate this solid mechanic

91 vancements that aid in understanding disease mechanics are based on animal studies.

92 We suggest that such airfoil-like mechanics are highly efficient, because they require ver

93 Tissue microarchitecture and mechanics are important in development and pathologies o

94 Since underlying mechanics are incompletely understood, we investigated l

95 ate that the changes in cytoarchitecture and mechanics are intrinsically driven by topographical conf

96 Microtubule structure, dynamics, and mechanics are modulated by a cell's choice of tubulin is

97 ges from pulsed events, and how tissue-level mechanics are the coordinated output of many individual

98 While many aspects of actin-cortex mechanics are well characterized, a mechanistic understa

99 The mechanics are well-captured by a model in which actin fi

100 assive force-SL relation and single molecule mechanics, are much smaller than what is required to avo

101 n of codon choice has been influenced by DNA mechanics around gene-body nucleosomes.

102 Classical fracture mechanics, as well as current commercial software, predi

103 s heterogeneous and non-monotonic due to the mechanics associated with internal convection and capill

104 enous fistula (AVF) causes aberrant vascular mechanics at and near the AVF anastomosis.

105 followed by matching the surrounding tissue mechanics at body temperature.

106 al tensions in HA, causing variations in the mechanics at much longer length scales.

107 keleton is a major contributor to epithelial mechanics at this stage.

108 mechanochemical-based adaptation coupling a mechanics-based physical model of cell tension coupled w

109 Using a statistical mechanics-based torsional spring model, we extracted val

110 cortex is thought to have key roles in cell mechanics, but remains a poorly characterized part of th

111 t baseline, Asm(-/-) mice showed better lung mechanics, but unaltered bronchial hyperresponsiveness.

112 ied with computational chemistry and quantum mechanics by molecular dynamics simulation program befor

113 es with efficiencies comparable to molecular-mechanics calculations on the solute alone; as such, the

114 ar dynamics, and excitonic quantum/molecular mechanics calculations to examine and rationalize CR bin

115 pid-quench flow, quantum/mechanics molecular mechanics calculations, crystallography, and detection o

116 ions, and mixed quantum mechanical/molecular mechanics calculations, yielding a comprehensive underst

117 simulations and quantum mechanics/molecular mechanics calculations.

118 development, while misregulation of cellular mechanics can promote disease.

119 nor is it understood how microstructure and mechanics change with onset and progression of POP.

120 ns in the biology, chemistry, materials, and mechanics communities.

121 These mechanics contrast with those previously reported in lam

122 However, whether cell surface mechanics control the process of differentiation has bee

123 There was no mechanics-derived evidence of endocardial dysfunction wi

124 Echocardiograms were used to measure cardiac mechanics: diastolic (lateral and septal E/e') and systo

125 ositive end-expiratory pressure, respiratory mechanics did not change significantly: compliance remai

126 dy examined how plantar flexor muscle-tendon mechanics during running differs between rearfoot and fo

127 Mechanics experiments were performed on fibres dissected

128 Our work reveals a paradigm whereby tissue mechanics fine-tune adaptive immune responses in health

129 ental equations, including that of classical mechanics, fluid physics, statistical physics, astrophys

130 to mediate the improvements in structure and mechanics following a 1-mm midsubstance injury.

131 ls, with the goal of matching tissue and ECM mechanics for in vitro tissue models and applications in

132 cues, allowing the cell to rapidly tune its mechanics from highly cross-linked, elastic networks to

133 intained for 20 minutes, and afterward, lung mechanics, gas exchange, and electrical impedance tomogr

134 Here we show that membrane mechanics gate exit from naive pluripotency of mouse emb

135 foundation for understanding prefusion-spike mechanics governing endosomal entry; we suggest that the

136 Despite their critical roles, the precise mechanics governing TRM cell reactivation in situ are un

137 Quantum mechanics governs the microscopic world, where low mass

138 Computational models of envelope mechanics have assumed values of the flexural stiffness

139 ties, remarkable flexibility (soft polymeric mechanics having hard inorganic matrix), nanoscale-level

140 Thus, our study reveals that chromosome mechanics help to re-establish the compartmentalization

141 ssed this problem by developing hidden fluid mechanics (HFM), a physics-informed deep-learning framew

142 iating keratinocytes, with an impact on cell mechanics, homeostasis and barrier function in epidermis

143 st deformation is assumed to dominate tissue mechanics. However, the mechanical responses of soft tis

144 een a core metabolic process and large-scale mechanics in a rapidly developing embryo.

145 e-field-like efficiency and captures quantum mechanics in an analytically differentiable representati

146 Fast sarcomere-level mechanics in contracting intact fibres from frog skeleta

147 s, the subtle interplay between topology and mechanics in elastic knots remains poorly understood.

148 In this paper, we study the role of membrane mechanics in governing the architecture of these tubes a

149 ntin controls actin network organization and mechanics in mitosis and is required for successful cell

150 Inspired by thermodynamics and statistical mechanics in physical systems, we developed a non-equili

151 he exploration of the foundations of quantum mechanics in unreached parameter spaces.

152 2+) and Ca(2+), on VIF network structure and mechanics in vitro.

153 ld protein anillin contributes to epithelial mechanics in Xenopus laevis embryos.

154 Common culprits of altered wound healing mechanics, including angiogenesis and inflammation, were

155 or an extensive control of the active bundle mechanics, including reversals of the filaments' apparen

156 Overall, this genome-scale map of DNA mechanics indicates a 'mechanical code' with broad funct

157 DNA has limited our understanding of how DNA mechanics influence chromatin transactions across the ge

158 As respiratory mechanics inherently support lung ventilation, 3D MR Spi

159 Through advanced assessment of muscle mechanics, innovative histology and oxygen tension model

160 dations of physics, establishes that quantum mechanics is a non-local theory.

161 An understanding of left ventricle (LV) mechanics is fundamental for designing better preventive

162 cell-substrate adhesion and linear cellular mechanics is sufficient to reproduce many nonlinear dyna

163 n cross-linking in controlling actin network mechanics is well-characterized in purified actin networ

164 ck models, including linear elastic fracture mechanics (LEFM), cohesive crack model (CCM), and extend

165 extrapulmonary form in terms of respiratory mechanics, lung recruitment, gas exchange, and positive

166 Our aim was to assess LV cardiac mechanics, LV twist, and the prevalence of rigid body ro

167 tissue, and suggest that measures of tissue mechanics may better resolve disease-specific difference

168 l framework to combine quantum and molecular mechanics methods, and compute the effect of methylation

169 inted cavities were simulated with molecular mechanics (MM) and molecular dynamics (MD).

170 fects might be expected, using a statistical mechanics model allowing for ideal, defective, and vacan

171 Quantitative mechanics modeling and experimental measurements illustr

172 Mechanics modeling reveals the critical role of the 1D C

173 U through hybrid quantum mechanics-molecular mechanics molecular dynamics simulations and free energy

174 ing stopped-flow, rapid-quench flow, quantum/mechanics molecular mechanics calculations, crystallogra

175 in an SNT called GlmU through hybrid quantum mechanics-molecular mechanics molecular dynamics simulat

176 ensity functional theory (DFT)-based quantum mechanics/molecular mechanics (QM/MM) calculations of th

177 Quantum mechanics/molecular mechanics (QM/MM) maturation of an i

178 gnetic resonance (EPR) spectroscopy, quantum mechanics/molecular mechanics (QM/MM) simulations, kinet

179 at 2.15 angstrom resolution and used quantum mechanics/molecular mechanics (QM/MM) to investigate its

180 f molecular dynamics simulations and quantum mechanics/molecular mechanics calculations.

181 mputational methods (ligand docking, quantum mechanics/molecular mechanics optimization, and molecula

182 mbrane-embedded PSII with high-level quantum-mechanics/molecular-mechanics (QM/MM) calculations of in

183 r anterior bodies using leading-edge suction mechanics, much like an airfoil.

184 onlocal effects, even at the macroscales, in mechanics, nonlocality is a higher-order effect that bec

185 By close consideration of the geometry and mechanics of 2 lobes of the mantle, constrained both by

186 ope to enable researchers to interrogate the mechanics of a much broader range of proteins than is cu

187 Here, we study the morphology and mechanics of adenovirus particles with (Ad5-wt) and with

188 enopus laevis egg extract to investigate the mechanics of aster movement and centration.

189 s materials rather than molecules, (iii) the mechanics of cluster extraction and subsequent chemistry

190 nsight into biological phenomena or abstract mechanics of complex systems.

191 eviously developed theory which combines the mechanics of contact of soft objects and the scattering

192 eneration at low temperature; and detail the mechanics of DNA repair and RNA processing at low temper

193 both of which are important in defining the mechanics of DNA supercoiling.

194 ial curling to characterize the out-of-plane mechanics of epithelial monolayers.

195 The mechanics of fibronectin-rich extracellular matrix regul

196 nd are often embedded in noise; however, the mechanics of force-sensing proteins have only been teste

197 udy, experimentally and computationally, the mechanics of gas percolation under hydrate-forming condi

198 set of data on the structure, kinetics, and mechanics of hGFAT2, which will certainly contribute to

199 Understanding the mechanics of kinesin-8's microtubule end activity will p

200 Although much is known about the mechanics of ligand binding and PRR activation, how cell

201 However, many details of the mechanics of M/R chromosomal manipulation during DNA-rep

202 t hydration is widely underestimated for the mechanics of macromolecules and that a polymer chain has

203 The structure and mechanics of many connective tissues are dictated by a c

204 erve as the foundation for understanding the mechanics of more physiological F-actin networks with tu

205 rial design for their ability to enhance the mechanics of polymeric materials and impart biological f

206 To better understand the mechanics of postnatal transmission, we performed a comp

207 ed to have caused a global revolution in the mechanics of rivers.

208 method can provide for new insights into the mechanics of single adherent cells versus time.

209 robust understanding of the development and mechanics of striated muscles.

210 relative importance of effects defining the mechanics of suspensions comprising soft particles.

211 tance of TBR for swallowing performance, the mechanics of TBR are poorly understood.

212 By altering the contractile mechanics of the cardiomyocyte, myosin inhibitors have t

213 The mechanics of the cellular microenvironment continuously

214 epigenetic marks by modifying the structural mechanics of the chromosome.

215 an unprecedented view of the conformational mechanics of the knot and its relationship to the activa

216 a combined testbed to investigate nanoscale mechanics of the living cell membrane.

217 rate tensor, and quantitatively describe the mechanics of the molecular ligand binding/dissociation o

218 these direct observations reveal the working mechanics of the molecular logic OR in PPHK, where the l

219 nd nanoindentation allowed us to measure the mechanics of the overlap and gap regions in the D-bandin

220 h can even result in colloidal gelation, the mechanics of the suspension can be quantified in terms o

221 at least two ways that are modulated by the mechanics of the tumor and its stroma.

222 ntramolecular rotation, which depends on the mechanics of their direct surroundings, with their fluor

223 The dynamics and mechanics of these ferritin-PIX were devoid of direction

224 However, the precise mechanics of these functions are little understood.

225 simulations, how these mutations affect the mechanics of this interface, performing two different cl

226 To address the mechanics of this process, we fluorescently labeled the

227 al compression, which respectively mimic the mechanics of tumour growth and of surgical resection.

228 on measurements relate quantitatively to the mechanics of virus adhesion to the cell.

229 In particular, piezo-mechanics operating at typical superconducting qubit fre

230 (ligand docking, quantum mechanics/molecular mechanics optimization, and molecular dynamic simulation

231 or achieved in this way provides a continuum-mechanics platform for advanced strain-field engineering

232 role chromosome organization and structural mechanics play in the spreading of histone modifications

233 dynamic simulations combined with Molecular Mechanics-Poisson Boltzmann Surface Area calculations id

234 means that a wide range of problems in solid mechanics, previously thought to be fundamentally intrac

235 hanics approximations to evaluate this solid mechanics problem.

236 LA compliance and mechanics progressively decline with increasing AF burde

237 sclerotic plaque, it also regulates cellular mechanics, proliferation and migration in atherosclerosi

238 resent a combined molecular dynamics/quantum mechanics protocol that accurately predicts experimental

239 k for decision-making that, by using quantum mechanics, provides more generalised cognitive and decis

240 ally means time-consuming high-level quantum mechanics (QM) calculations are required.

241 Quantum mechanics (QM) calculations confirm, as expected, that t

242 We employ an extensive series of quantum mechanics (QM) calculations to delineate how the electro

243 or including such information is the quantum mechanics (QM).

244 with high-level quantum-mechanics/molecular-mechanics (QM/MM) calculations of individual and coupled

245 eory (DFT)-based quantum mechanics/molecular mechanics (QM/MM) calculations of the crystals evidence

246 Quantum mechanics/molecular mechanics (QM/MM) maturation of an immunoglobulin (Ig) p

247 R) spectroscopy, quantum mechanics/molecular mechanics (QM/MM) simulations, kinetic studies, and the

248 olution and used quantum mechanics/molecular mechanics (QM/MM) to investigate its reaction mechanism.

249 mental importance for understanding how cell mechanics regulates biochemical signaling and therefore

250 Altogether, our data show that tissue mechanics regulates therapeutic outcome and long-term su

251 ional materials, where cellulose's structure-mechanics relationships are pivotal.

252 c rates regardless of changing environmental mechanics, retain PFK expression by downregulating TRIM2

253 Numerical modeling of LC and cell mechanics reveals that RBC shape responses occur at cons

254 Fluid dynamics and solids mechanics should be considered in planning of stenting f

255 ss enhancements using computational fracture mechanics simulations.

256 r/mm vs 3.5 +/- 0.9 br/mm, P=0.043) and lung mechanics (static elastance 61 +/- 36 cmH2O /mL vs 113 +

257 These changes in gastrocnemius mechanics suggest that runners planning to convert to fo

258 Johnson-Kendall-Roberts (JKR) contact mechanics test was performed using a titanium (Ti) spher

259 Contact mechanics testing further confirmed that the Young's mod

260 t modifications to cardiac ECM structure and mechanics that contribute to HF and (2) determine the un

261 4) centrosomes and cell cortex to understand mechanics that determines three-dimensional spindle arch

262 gnificantly improve our understanding of the mechanics that drive the initiation of damage in the com

263 In quantum mechanics, the Heisenberg uncertainty relation presents

264 Finally, we used linear elastic fracture mechanics theory to predict where surface fractures woul

265 that rather than actual enhancement of cell mechanics, these observations are "pseudoimprovements" a

266 , limitations, and the passive physiological mechanics they employ to land on a vertical surface.

267 or connecting protein filament structure and mechanics to cellular organization and function.

268 Here we show how to use statistical mechanics to construct operators able to flexibly predic

269 ibution of cancer cell-derived ECM and tumor mechanics to drug adaptation and therapy resistance rema

270 We utilize quantum mechanics to evaluate a variety of plausible mechanistic

271 f migratory routines that are independent of mechanics to facilitate invasion.

272 ssue-scale forces converge on local cellular mechanics to generate complex forms and modulate cell-fa

273 Here, we used computational mechanics to investigate changes in stress distribution

274 tests of various collapse models of quantum mechanics to miniature quantum memory elements in hybrid

275 itory system and exert influence on cochlear mechanics to modulate perception of acoustic stimuli.

276 cal studies on single cells have linked cell mechanics to physiology, functionality and disease.

277 tial kinetics (GCP-K) formulation of quantum mechanics to predict the kinetics as a function of appli

278 f fractures based on linear elastic fracture mechanics to predict where basal and dry surface fractur

279 that Ca(2+) specifically acts downstream of mechanics to regulate PIN1 polarity response.

280 aling with membrane tension and cytoskeletal mechanics to show how signaling events are coupled to re

281 omputers utilize the fundamentals of quantum mechanics to solve computational problems more efficient

282 passing local differential growth and tissue mechanics, to investigate tissue fold positioning.

283 lecule force spectroscopy studies of protein mechanics, to serving as force-bearing protein linker fo

284 s a feasible technique to assess respiratory mechanics under physiological conditions.

285 resent a detailed investigation of the fluid mechanics underlying the formation of nanoliter compartm

286 In this progress report, multiscale mechanics understanding of cellulose, including the key

287 ication to mouse-specific models of arterial mechanics using an experimentally informed four-fiber co

288 e assessed arterial blood gases, respiratory mechanics, ventilation inhomogeneity, and potential for

289 ons of general relativity, chaos and quantum mechanics via a universal geodesic equation.

290 Inspired by replica theory from statistical mechanics, we consider replicas of the system to tune th

291 Starting from first-principles statistical mechanics, we more rigorously motivate this empirical ob

292 cross-sectional study nano- and tissue-level mechanics were compared across trabecular sections from

293 Lung mechanics were evaluated in three groups of children: as

294 Collagen fibril, mineral and tissue mechanics were measured using synchrotron X-Ray diffract

295 tions such as metalworking, woodworking, and mechanics, which are, in turn, significantly correlated

296 ne factor that affects cell motility is cell mechanics, which is known to be related to substrate sti

297 However, the contributions of mechanics, while being central to the process of biofilm

298 onal thermoplastics cannot match soft tissue mechanics, while gels leach into the body and alter thei

299 chnology such as photonics, electronics, and mechanics with a wide range of applications from tissue

300 en microglia, vascular patterning and tissue mechanics within the CNS.