ライフサイエンスコーパス: mechanism that underlie

1 Hence, understanding the mechanisms that underlie A3B over-expression is importan

2 n can improve understanding of the molecular mechanisms that underlie abnormal eye development and im

3 Our findings thus unravel a circuit mechanism that underlies accurate detection of harmful s

4 We therefore investigated the cellular mechanisms that underlie acquired benzodiazepine resista

5 Here we investigated the molecular mechanisms that underlie acquired resistance to BRAFi an

6 rovide guidance for understanding the neural mechanisms that underlie age-dependent reductions in the

7 ur findings offer critical insights into the mechanisms that underlie AIPL1 function in health and di

8 onal pentameric structure in cell lines, and mechanisms that underlie alpha7 receptor assembly in neu

9 ies, it is critical to better understand the mechanisms that underlie AML progression.

10 s new insight into genetic and physiological mechanisms that underlie an ecologically relevant form o

11 onsider possible physiological and cognitive mechanisms that underlie an individual's ability to make

12 These data shed new light on the molecular mechanism that underlies anti-CD3-mediated immune resett

13 vaccines and antibody therapies because the mechanisms that underlie antibody protection against any

14 uired to gain protection and, lastly, 3) the mechanisms that underlie any association.

15 gaps concerns a refined understanding of the mechanisms that underlie arsenic mobilization, particula

16 Although much is known about the brain mechanisms that underlie associations with dangerous tas

17 ful for investigating the pathophysiological mechanisms that underlie asthma and the development of m

18 s a potential route to unraveling the neural mechanisms that underlie awareness itself.

19 co-culture model recapitulates key molecular mechanisms that underlie bacteria-induced neutrophil tra

20 Elucidating elementary mechanisms that underlie bacterial diversity is central

21 ocyte IL-1beta production represents a novel mechanism that underlies behavioral complications associ

22 Our understanding of the genetic mechanisms that underlie biological processes has relied

23 e comparable results indicate similar neural mechanisms that underlie both the ETS and EAS effects.

24 ide the capability of identifying biological mechanisms that underlie brain disorders.

25 ates from this epithelium, but the molecular mechanisms that underlie breast epithelial hierarchy rem

26 ying clonal mosaicism to uncover fundamental mechanisms that underlie cancer and other ageing-related

27 e evidence to support RNA degradation as the mechanism that underlies Cas9-mediated regulation of FTN

28 ation and evolve towards malignancy, but the mechanisms that underlie cell death in crisis are not we

29 These data provide insights into a potential mechanism that underlies changes in gene expression in t

30 urther improve our knowledge of the cellular mechanisms that underlie changes in PET signal, how immu

31 2 channel architecture and symmetry, and the mechanism that underlies channel inhibition.

32 ss the regulation of chylomicron production, mechanisms that underlie chylomicron dysregulation, and

33 These results identify a molecular mechanism that underlies complex interactions between th

34 SAM also enabled identification of potential mechanisms that underlie components of memory, thus reve

35 the structures, kinetics, thermodynamics and mechanisms that underlie conformational exchange process

36 tivity has hampered our understanding of the mechanisms that underlie contextual modulation of sensor

37 requires p38alpha MAPK, but transcriptional mechanisms that underlie cytokine-driven selectin ligand

38 To elucidate the biochemical mechanisms that underlie detoxification and pathogen-imm

39 This article reviews the potential mechanisms that underlie development of APOL1-associated

40 Although the immunological mechanisms that underlie different clinical trajectories

41 tools for elucidating the neuropathological mechanisms that underlie different disorders.

42 The mechanisms that underlie directional cell migration are

43 es, with little regard for the heterogeneous mechanisms that underlie disease manifestation across in

44 rapy, with a primary focus on the resistance mechanisms that underlie disease relapse.

45 d-type D2R, signifying a dissociation in the mechanisms that underlie distinct D2R-dependent behavior

46 The molecular mechanisms that underlie distinct instances of necroptos

47 The molecular mechanisms that underlie disuse atrophy are poorly under

48 rphological diversity, and the developmental mechanisms that underlie diversification are of signific

49 We explore the receptor-specific mechanisms that underlie dopaminergic control of spinal

50 es; therefore, elucidation of the epigenetic mechanisms that underlie drug resistance may greatly con

51 Our study identifies a mechanism that underlies effects of circadian disruption

52 preclinical studies designed to evaluate the mechanisms that underlie efficacy of PTCy after alloHSCT

53 findings provide insight into the molecular mechanisms that underlie enteric symbiont-stimulated sys

54 However, the molecular mechanisms that underlie excitatory synaptogenesis are o

55 Molecular and cellular mechanisms that underlie FA-induced damage are poorly un

56 e not rich enough to allow identification of mechanisms that underlie food insecurity and overweight

57 is work establishes the molecular origin and mechanism that underlie formation of unique carbon cage

58 eurodevelopmental, and psychopharmacological mechanisms that underlie genetic variation-associated co

59 anding of the neurobiological and behavioral mechanisms that underlie greater risk of heroin addictio

60 fundamental element to our knowledge of the mechanisms that underlie H2O2 electrochemistry.

61 epidemiologists often seek to determine the mechanisms that underlie health disparities.

62 nt medical condition; however, the molecular mechanisms that underlie heightened pain processing rema

63 a and neurons remains poorly defined, as the mechanisms that underlie how these tumours remodel the n

64 Unravelling the complex mechanisms that underlie human brain astrocyte-neuron in

65 he systematic investigation of the molecular mechanisms that underlie human diseases.

66 ls is essential for identifying the cellular mechanisms that underlie human genetic traits and diseas

67 moting inflammatory responses(7-12), but the mechanisms that underlie immunodeficiency remain undefin

68 The mechanisms that underlie immunosuppression, however, rem

69 itness and pre-mating reproductive isolation mechanisms that underlie incipient sympatric speciation.

70 hat could yield substantial insight into the mechanisms that underlie individual differences in child

71 pen new research avenues into the biological mechanisms that underlie individual variation in shift w

72 is work provides insights into the molecular mechanisms that underlie inflammatory lung disease.

73 a thriving field of research, the biological mechanisms that underlie information integration in the

74 N and FPCN(A) is a core electrophysiological mechanism that underlies internally directed attention.

75 The mechanisms that underlie irAEs from immune checkpoint in

76 e perceptual importance of pitch, the neural mechanisms that underlie it remain poorly understood.

77 t in understanding vitamin D biology and the mechanisms that underlie its actions.

78 ated by the heterogeneous pathophysiological mechanisms that underlie its clinical presentation, whic

79 The relevant computational and motivational mechanisms that underlie its heterogeneity, however, are

80 ent insights into the cellular and molecular mechanisms that underlie its pivotal roles in atheroscle

81 romere protein A (CENP-A), but the molecular mechanisms that underlie its remarkable stability remain

82 for Bipolar Disorder although the molecular mechanisms that underlie its therapeutic effects are und

83 nd intra-lineage diversity in the targetable mechanisms that underlie KRAS-driven cancers, limited ph

84 not only aid in the discovery of the genetic mechanisms that underlie local adaptation but also provi

85 optimal diets to understanding the molecular mechanisms that underlie male and female responses to di

86 seeding will help clarify the physiological mechanisms that underlie mast seeding.

87 Our results suggest that the prefrontal mechanisms that underlie mature performance on the antis

88 The mechanisms that underlie MDM4 upregulation in cancer cel

89 s via reaction kinetics may help unravel the mechanisms that underlie metabolic changes in tumors.

90 a novel molecular contributor to the complex mechanisms that underlie metastasis in colorectal cancer

91 We focus on phenotypes and mechanisms that underlie microvascular aging, the greate

92 However, the mechanisms that underlie mitotic transcriptional regulat

93 eceptor activity, in most cases the detailed mechanisms that underlie modulation are poorly understoo

94 However, the molecular mechanisms that underlie modulation of cancer stem cells

95 findings provide insights into the molecular mechanisms that underlie mutagenesis and are relevant to

96 behaviors to facilitate the study of neural mechanisms that underlie naturalistic behaviors.

97 paper focuses on the cellular and molecular mechanisms that underlie neural-cardiac interactions dur

98 Our data support a neuroimmune mechanism that underlies neurodevelopmental disorders in

99 xtension (CE) is a fundamental morphogenetic mechanism that underlies numerous processes in vertebrat

100 However, the molecular mechanisms that underlie oncogene-induced replication st

101 Mechanisms that underlie partitioning of the genome into

102 ctions, especially viral infections, but the mechanisms that underlie pathogenesis are unknown.

103 tor, NOGGIN, generating a reaction-diffusion mechanism that underlies patterning.

104 6A deficiency with a cell-specific molecular mechanism that underlies PDAC subtype definition.

105 een difficult to identify the neural circuit mechanisms that underlie persistent activity and contrib

106 pens several questions for understanding the mechanism that underlies phosphorylation and how phospho

107 estigations into the structure and molecular mechanisms that underlie plant PSII function.

108 l populations is an evolutionarily conserved mechanism that underlies population survival upon stress

109 f cognitive impairment and dementia, but the mechanisms that underlie post-stroke cognitive decline a

110 Little is known about mechanisms that underlie postnatal hepatocyte maturation

111 ase resistance, but we do not understand the mechanisms that underlie protective immunity to Cryptosp

112 The genomic mechanisms that underlie pulmonary immune responses to f

113 The mechanisms that underlie recovery after injury of the ce

114 Elucidating the brain mechanisms that underlie relapse is critical for evidenc

115 ropose a positive appraisal style as the key mechanism that underlies resilience.

116 ns and have identified some of the genes and mechanisms that underlie resistance.

117 Advances in understanding of the molecular mechanisms that underlie restless legs syndrome could le

118 50K mutation in the pathogenic mitochondrial mechanism that underlies retinal ganglion cell (RGC) deg

119 is type I-C Cascade, revealing the molecular mechanisms that underlie RNA-directed complex assembly.

120 t a recent surge of studies of the proximate mechanisms that underlie search behavior offers a new op

121 does not allow us to discern the finer scale mechanisms that underlie sensory plasticity.

122 of IL-33 in the airways and IL-33-dependent mechanisms that underlie severe asthma exacerbations.

123 Therefore, new understandings of the mechanisms that underlie socioeconomic differences in in

124 uitry of the basal ganglia and highlight the mechanisms that underlie some of the major movement diso

125 20) provides an opportunity to elucidate the mechanisms that underlie spatial compartmentalization.

126 vironments, and shed new light on the neural mechanisms that underlie spatial navigation and awarenes

127 The molecular mechanisms that underlie spleen development and congenit

128 bset of kidney transplant recipients, immune mechanisms that underlie successful vs unsuccessful Tac

129 The mechanisms that underlie such branch loss are largely un

130 indings raise new questions about the neural mechanisms that underlie such dynamic representational s

131 However, the molecular mechanisms that underlie such population control are unc

132 anding the selective pressures and molecular mechanisms that underlie such tremendous morphological v

133 The mechanisms that underlie superficial erosion, a cause of

134 To identify the mechanisms that underlie susceptibility to EBV lytic act

135 The mechanisms that underlie susceptibility to infection in

136 on gleaned from pathogen genomes can uncover mechanisms that underlie sustained spread and, in turn,

137 However, the molecular mechanisms that underlie symbiont-mediated host immunity

138 rain disorders, yet we know little about the mechanisms that underlie synaptic vulnerability.

139 The pathological mechanisms that underlie T helper type 2 cell-driven (Th

140 vely, these studies provide insight into the mechanisms that underlie TDP-43 proteinopathy and presen

141 et al. explore transcription infidelity as a mechanism that underlies the ability of these benign pro

142 The regulatory mechanism that underlies the Ace2-to-Ace pathological sw

143 cal adhesion maturation suggests a molecular mechanism that underlies the beneficial effect of Bis-T-

144 emory engrams could be an important cellular mechanism that underlies the cognitive symptoms of depre

145 by entry into the lymphatic system may be a mechanism that underlies the entry and spread of other t

146 ation/microcalcification and may clarify the mechanism that underlies the genetic association between

147 Our findings reveal a neural mechanism that underlies the mechanosensory monitoring o

148 s glucokinase activation may represent a CNS mechanism that underlies the oft-described phenomena of

149 The mechanism that underlies the regulation of PICK1-Ago2 bi

150 potential, it is critical to understand the mechanisms that underlie the 'retrieval-extinction' effe

151 lus can be dissociated in the brain from the mechanisms that underlie the ability to behave in a mean

152 defenses, but the molecular and biochemical mechanisms that underlie the activation of phloem-locali

153 The mechanisms that underlie the activation of RLCKs are unc

154 However, the mechanisms that underlie the association between asthma

155 ea of the macaque monkey to study the neural mechanisms that underlie the behavioral consequences of

156 Here we elucidate the molecular and neural mechanisms that underlie the beneficial effects of infla

157 c content analyses to investigate the neural mechanisms that underlie the biased processing of real-w

158 about the computational strategies or neural mechanisms that underlie the brain's ability to perform

159 and discuss the current understanding of the mechanisms that underlie the broad, yet highly cell- and

160 ohepatitis, the delineation of the potential mechanisms that underlie the cardiovascular benefit and

161 , we review the current understanding of the mechanisms that underlie the complex interactions betwee

162 ere, we review these studies and discuss the mechanisms that underlie the construction and turnover o

163 ovided detailed insights into many molecular mechanisms that underlie the detection of signals and th

164 A comprehensive understanding of mechanisms that underlie the development and function of

165 detailed understanding of the immunological mechanisms that underlie the development of allergic dis

166 To identify the mechanisms that underlie the differences in function and

167 s well characterized at the molecular level, mechanisms that underlie the direct effect of light on b

168 The biochemical and evolutionary mechanisms that underlie the diversity of this DNA-bindi

169 Transcriptional mechanisms that underlie the dose-dependent regulation o

170 Understanding the precise immunological mechanisms that underlie the efficacy of chemotherapy ha

171 A better understanding of the molecular mechanisms that underlie the enhanced resistance to AKI

172 lenecks during transmission to shed light on mechanisms that underlie the evolution and propagation o

173 resently a very limited understanding of the mechanisms that underlie the evolution of new cell types

174 Understanding the genetic mechanisms that underlie the evolution of weedy crop rel

175 increased gene expression, but the molecular mechanisms that underlie the exquisite specificity of th

176 The molecular mechanisms that underlie the formation of chromosome ter

177 We discuss neural circuit mechanisms that underlie the generation and regulation o

178 However, the mechanisms that underlie the highly specific assembly of

179 ries of experiments to identify the cellular mechanisms that underlie the hyperexcitability reported

180 Understanding the brain mechanisms that underlie the impact that emotional assoc

181 is work summarizes research on the molecular mechanisms that underlie the increased risk of cancer de

182 tes are maintained by synaptic activity, the mechanisms that underlie the initiation and robust rhyth

183 un to investigate the molecular and cellular mechanisms that underlie the interaction between nutriti

184 The mechanisms that underlie the interaction between these n

185 es the therapeutic application and molecular mechanisms that underlie the intricate interactions betw

186 allows for modeling and detailed analysis of mechanisms that underlie the M-SOB effect in not only MS

187 roaches, we uncover cellular hierarchies and mechanisms that underlie the maintenance and repair of t

188 These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease

189 The molecular and cellular mechanisms that underlie the many roles of macrophages i

190 We cover an ample array of known mechanisms that underlie the metabolic regulation of KIS

191 pathways, and the genetic and developmental mechanisms that underlie the morphogenesis of TME struct

192 imating Ne , and identifying key demographic mechanisms that underlie the Ne to census population siz

193 mportant first step toward understanding the mechanisms that underlie the onset of edema and ICP in c

194 re has not been implemented with the genetic mechanisms that underlie the organization of gene cluste

195 al to cancer cell invasion, but the specific mechanisms that underlie the particularly invasive pheno

196 f asthma; however, little is known about the mechanisms that underlie the pathogenesis of the disease

197 vide a better understanding of the molecular mechanisms that underlie the persistence of EV forms in

198 espite the widespread use of this model, the mechanisms that underlie the persistent behavioural chan

199 no real understanding yet of the structural mechanisms that underlie the potential destabilizing eff

200 vide insights into distinguishing the neural mechanisms that underlie the predisposition to drug addi

201 Understanding the molecular mechanisms that underlie the presence or absence of a sp

202 rovide novel insight into the dynamic neural mechanisms that underlie the processing of somatosensory

203 The evolutionary mechanisms that underlie the rapid evolution of centrome

204 ce about the tissue, cellular, and molecular mechanisms that underlie the reduction in pacemaker acti

205 podocytopathy; therefore, understanding the mechanisms that underlie the regulation of calcium/calci

206 s in understanding the systemic and cellular mechanisms that underlie the regulation of iron homeosta

207 However, investigating the molecular mechanisms that underlie the regulation of photosynthesi

208 facilitated the identification of molecular mechanisms that underlie the regulation of renal and int

209 Thus, an understanding of the molecular mechanisms that underlie the resistance to ART and the p

210 Understanding the trafficking mechanisms that underlie the role of ciliary compartment

211 The mechanisms that underlie the sequestration of these sub-

212 These observations reveal mechanisms that underlie the specific programming and pr

213 Here we focus on mechanisms that underlie the stimulation of G by ephrins

214 rther dissect the complex pathophysiological mechanisms that underlie the tissue specificity of the m

215 Gaining insights into the regulatory mechanisms that underlie the transcriptional variation o

216 taset will also allow hypothesis-testing for mechanisms that underlie the transition from aging to AM

217 tegrate accounts of the neuropharmacological mechanisms that underlie the transition to compulsion wi

218 oubts remain about the precise photophysical mechanism that underlies their peculiar spectroscopic pr

219 ound throughout the brain, the circuit-level mechanisms that underlie their computation are still lar

220 nsion for psychological well-being, identify mechanisms that underlie their cultivation, and present

221 eless, due to their amorphous structure, the mechanisms that underlie their ionic conductivity remain

222 uli, but the neuronal circuits and molecular mechanisms that underlie them are not well understood.

223 emporal changes in these populations and the mechanisms that underlie them have heretofore been uncle

224 s the discrete biomechanical and biochemical mechanisms that underlie these architectural changes and

225 The pathogenic mechanisms that underlie these associations could be lev

226 Understanding the mechanisms that underlie these associations may provide

227 Understanding the mechanisms that underlie these associations might provid

228 However, the mechanisms that underlie these behaviors are poorly unde

229 by fever; however, little is known about the mechanisms that underlie these beneficial effects.

230 However, the physiological mechanisms that underlie these changes are not fully und

231 To ascertain the molecular mechanisms that underlie these contrasting phenotypes, w

232 ges in several brain areas, but the cellular mechanisms that underlie these defects are not understoo

233 cover molecular, cellular, and circuit-level mechanisms that underlie these deficits and successfully

234 differentiation into effector cells, but the mechanisms that underlie these distinct outcomes remain

235 However, the cellular mechanisms that underlie these durable changes remain po

236 To investigate the network-level mechanisms that underlie these dynamics, we developed no

237 ocal inhibitory interneurons, as well as the mechanisms that underlie these dynamics.

238 However, the mechanisms that underlie these effects are not well-esta

239 attenuate cognitive decline in aging and the mechanisms that underlie these effects should be investi

240 the triggers of acute exacerbations, and the mechanisms that underlie these exacerbations.

241 Future studies may explain the mechanisms that underlie these findings.

242 ike the functions of lncRNA transcripts, the mechanisms that underlie these genome-based functions ar

243 l insights into their functional overlap and mechanisms that underlie these genomic features and thei

244 g of the genetic architectures and molecular mechanisms that underlie these interactions, we comprehe

245 Little is known about the neural mechanisms that underlie these memory processes.

246 exclusive hypotheses concerning the neuronal mechanisms that underlie these perceptual improvements.

247 is known about sex differences in the neural mechanisms that underlie these phenomena.

248 However, the mechanisms that underlie these phenotypes remain unknown

249 Understanding the molecular mechanisms that underlie these plastic changes is a majo

250 The neural mechanisms that underlie these processes are not well un

251 nd burial of C within inland waters, yet the mechanisms that underlie these processes are poorly cons

252 ological neural plasticity, and studying the mechanisms that underlie these processes, including rein

253 ivity and provide insight into the molecular mechanisms that underlie these processes.

254 cilium itself, and our understanding of the mechanisms that underlie these rapid, regulated alterati

255 However, in most patients, the mechanisms that underlie these symptoms are unknown.

256 g the field's understanding of the molecular mechanisms that underlie these syndromes.

257 the splicing factor SRSF6 is involved in the mechanism that underlies this aberrant splicing event.

258 The molecular mechanism that underlies this dual substrate specificity

259 s yet to be provided, and the exact chemical mechanism that underlies this transformation remains elu

260 ct (LFRT) compared to other tissues, but the mechanism that underlies this vulnerability is poorly un

261 The molecular mechanisms that underlie this adaptation remain unknown.

262 nt, little is known about the neurocognitive mechanisms that underlie this adaptive phenomenon, since

263 a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized

264 However, the molecular mechanisms that underlie this balance remain elusive.

265 infants fed with maternal milk, although the mechanisms that underlie this benefit are not clear(4-6)

266 rt failure and adverse renal events, but the mechanisms that underlie this benefit are not understood

267 o shed light on the molecular and regulatory mechanisms that underlie this complex process.

268 The mechanisms that underlie this coordination are currently

269 The physiological mechanisms that underlie this default output state, howe

270 serve as a valuable tool for analyses of the mechanisms that underlie this devastating side effect of

271 The molecular mechanisms that underlie this developmental process, kno

272 ry than their cortical counterparts, but the mechanisms that underlie this difference are unclear.

273 However, the molecular mechanisms that underlie this dysfunction remain unclear

274 c health in both rodents and humans, but the mechanisms that underlie this effect remain unknown.

275 The mechanisms that underlie this inflammation are poorly un

276 e development of insulin resistance, but the mechanisms that underlie this link remain unclear.

277 The mechanisms that underlie this neuropathy are not defined

278 However, the mechanisms that underlie this phenomenon remain poorly u

279 s CD4 independence provide new insights into mechanisms that underlie this phenotype.

280 However, the cellular and molecular mechanisms that underlie this priming effect remain poor

281 little is known about the precise molecular mechanisms that underlie this process.

282 ent and provide the mechanical and molecular mechanisms that underlie this process.

283 ory (ARM) was described decades ago, but the mechanisms that underlie this protein synthesis-independ

284 pinal cord injury(1); however, the molecular mechanisms that underlie this regeneration are unknown.

285 nforcing; however, the neuronal circuits and mechanisms that underlie this reinforcement are still no

286 stems have long been recognized, the precise mechanisms that underlie this relationship are just star

287 Although the pathophysiological mechanisms that underlie this relationship are poorly un

288 inflammatory response by phagocytes, but the mechanisms that underlie this response are still being d

289 e a sexually selected trait, the explanatory mechanisms that underlie this selection are poorly under

290 experience chronic pain than males, but the mechanisms that underlie this sex difference are not com

291 The mechanisms that underlie this specialization are not wel

292 s system to separate signals from noise, the mechanisms that underlie this suppression of activity ar

293 However, the mechanisms that underlie this susceptibility remain inco

294 The molecular mechanisms that underlie this switch have not been defin

295 understanding of the cellular and molecular mechanisms that underlie this transition.

296 years have we begun to understand the basic mechanisms that underlie this unique sensation.

297 These changes not only provide molecular mechanisms that underlie TTNtv-associated ventricular re

298 modulation and how specific parameters drive mechanisms that underlie ultrasound neuromodulation.

299 ile parameters that can be used to elucidate mechanisms that underlie variations in CM function.

300 We also identify dynamical mechanisms that underlie various features of this ISR be