ライフサイエンスコーパス: mechanism through which

1 is essential to determine the physiological mechanisms through which 5-HT neurons in the dorsal raph

2 Here, we demonstrate a mechanism through which a distinct E3 ubiquitin ligase,

3 In summary, our study reveals a novel mechanism through which a SUMO protease regulates cell d

4 n and circuit modelling to reveal the neural mechanisms through which a zebrafish performs phototaxis

5 Nevertheless, the biological mechanisms through which ABO influences hemostasis have

6 However, the mechanism through which ACE2 modulates this inflammatory

7 This emphasis on readmission reduction is 1 mechanism through which ACOs improve value in a surgical

8 ithin lamina I neurons, providing a unifying mechanism through which activity may regulate plasticity

9 f this study was to elucidate the underlying mechanism through which adiponectin controls islet expan

10 nitial results suggest a specific biological mechanism through which adversity contributes to altered

11 ay accelerate biological aging, offering one mechanism through which adversity may increase risk for

12 the plausible underlying pathophysiological mechanisms through which AF may promote or lead to SCD,

13 tor for most chronic human diseases, but the mechanisms through which ageing confers this risk are la

14 transmission, which is thought to be a major mechanism through which altered mTOR signaling leads to

15 thematical analysis and gives insight on the mechanisms through which antigen availability controls t

16 This might represent a mechanism through which APOE amplifies pulmonary inflamm

17 quitylation and endocytosis, demonstrating a mechanism through which Art1 activity is regulated.

18 describe proteomic analyses that identified mechanisms through which ATR kinase inhibitors induce un

19 e research is needed to clarify the specific mechanisms through which bariatric surgery lowers cancer

20 The mechanism through which Bcl-xL is recruited to the MOM h

21 Here, we critically discuss the mechanisms through which Bcl-2 proteins influence cell f

22 ur study uncovers a noncanonical thermogenic mechanism through which beige fat controls whole-body en

23 Our results provide new insights into the mechanisms through which below-ground hydraulic traits,

24 In this study, the mechanisms through which Bifidobacterium longum strain B

25 Our data suggest mechanisms through which bile acid metabolites control h

26 ne overexpression supports rearrangements as mechanism through which cancer cells remodel their trans

27 basis of these substrate preferences and the mechanism through which catalysis is achieved remain unk

28 There is ongoing debate regarding the mechanism through which cation/proton antiporters (CPAs)

29 Our studies reveal mechanisms through which CaV2 gain-of-function mutations

30 s known about the underlying neural transfer mechanisms through which CE acts on learning.

31 ell size have been identified, the molecular mechanisms through which cell growth drives cell divisio

32 McTNs represent a previously unappreciated mechanism through which cells engage nanoporous HA matri

33 tures for plant CSCs or CESAs, the molecular mechanism through which CESA catalyzes cellulose synthes

34 Kinase oxidation is a critical signaling mechanism through which changes in the intracellular red

35 important implications for how we study the mechanisms through which child maltreatment affects ment

36 prevention technologies, which are important mechanisms through which child mortality can be reduced.

37 etween native and introduced species are one mechanism through which climate change may exacerbate ne

38 Here, we report on two mechanisms through which climate change may affect fatal

39 ce the fate of a cell lineage: we describe a mechanism through which coccal (round) cells rise to the

40 quire a sense of number does not specify the mechanisms through which cognitive control plays a role

41 Our results shed crucial insights into the mechanisms through which common early perinatal experien

42 Yet the biological mechanisms through which context modulate experiences ar

43 Our findings provide a mechanism through which CSCs persist in hostile environm

44 ortical actin in CTLs, providing a potential mechanism through which CTLs control cortical actin dens

45 Our results reveal important mechanisms through which cyst nematodes exploit componen

46 d in a conformation that revealed a possible mechanism through which D2 can allosterically inhibit D1

47 d DNAm as a potentially important biological mechanism through which developmental environments shape

48 Inflammation is a potential mechanism through which diet modulates the onset of infl

49 al behaviours in response to stress, but the mechanisms through which DISC1 affects stress responses

50 es of DOM for understanding the kinetics and mechanisms through which DOM interacts with metal and ot

51 insufficiency (HI) is the best characterized mechanism through which dominant mutations exert their e

52 Our study thus provides a unifying molecular mechanism through which dominant-acting calsequestrin mu

53 rd injury to better elucidate the underlying mechanisms through which donor cells interact with the h

54 f cortical prediction error signals is a key mechanism through which dopamine modulates inference and

55 Our findings reveal a novel mechanism through which drought can continue to affect e

56 To identify novel mechanisms through which dysfunction might occur, milk-d

57 One proposed mechanism through which early-life experiences influence

58 Our findings shed light on the mechanism through which ECT impairs episodic memory, and

59 Our results uncover mechanisms through which EDF1 coordinates multiple respo

60 Here, the authors unravel a mechanism through which EGF stimulation induces MIIP pho

61 Together, these data uncover a novel mechanism through which endodermal-myocardial communicat

62 etes (MKR mouse) was used to investigate the mechanisms through which endogenous hyperinsulinemia pro

63 However, the mechanisms through which endothelial cells transduce mec

64 We also discuss the underlying mechanisms through which ENPP1 exerts its pathological e

65 monstrate that histone modifications are one mechanism through which epigenetic information from a fa

66 Next, to define neurophysiologic mechanisms through which ES affects repair, microarray a

67 The molecular mechanisms through which established risk factors, such

68 We identify mechanisms through which excess glutamate can negatively

69 The precise mechanisms through which excessive ER stress impacts tro

70 These results explain the molecular mechanism through which extracellular Ca(2+) triggers th

71 However, the mechanism through which FAK functions in the complex is

72 Collectively, these results identify mechanisms through which FGF signaling regulates inner c

73 ed to mutations in the FOXF1 gene, molecular mechanisms through which FOXF1 mutations cause ACDMPV ar

74 Here, we explored the mechanism through which GCN5 controls transcription.

75 The mechanisms through which GDF15 reduces body weight remai

76 The mechanisms through which genetic mutations, present from

77 Identifying the mechanisms through which genetic risk causes dementia is

78 itecture of neural phenotypes and the neural mechanisms through which genetic risk for psychopatholog

79 However, the mechanisms through which genetic susceptibility to obesi

80 atment of Diamond Blackfan anemia (DBA), the mechanisms through which glucocorticoids regulate human

81 In this study, we identified a novel mechanism through which Gp1 mGluR mediates protein trans

82 together, these observations provide a novel mechanism through which GPCRs regulate cocaine's pharmac

83 iferation; thus, understanding the molecular mechanisms through which GPER regulates hippocampal func

84 However, the molecular mechanism through which H-NS senses temperature and othe

85 specifically removes oxidized bases, is one mechanism through which H. pylori infection may fuel the

86 These observations provide a mechanism through which HCMV induces global myelosuppres

87 We investigated the mechanisms through which HCV infection modulates donor-s

88 There are several mechanisms through which high iron status during pregnan

89 pinal cord, which might represent a flexible mechanism through which higher-cognitive representations

90 risk variants for SCZ and ASD and elucidate mechanisms through which highly penetrant, multigene cop

91 We evaluated the mechanism through which HIV-activated pDCs produce IFN a

92 irectly acting antiviral era and explore the mechanisms through which HIV itself induces liver damage

93 We now define the mechanisms through which HRD is induced in BRCA-proficie

94 However, the mechanisms through which HRVs modulate the immune respon

95 ese findings provide novel evidence that the mechanism through which HSPCs promote repair after strok

96 of HYAL2 is enzymatically inactive; thus the mechanisms through which HYAL2 dysregulation influences

97 In addition to the well understood mechanism through which hydroxyl radical (.OH) produced

98 nd procedural memory, provides an anatomical mechanism through which hypoxia may cause deficits in wo

99 These data identify Csk inhibition as the mechanism through which ibrutinib leads to AF.

100 efine an immune component of the pleiotropic mechanisms through which IGFBP7 suppresses HCC.

101 e-dependent antigen presentation and a novel mechanism through which IL-12 and IL-7 synergistically c

102 immune cell coculture model to determine the mechanism through which IL-33 affects intestinal goblet

103 as a therapeutic target and for defining the mechanisms through which immune-mediated disease variant

104 This result provides a mechanism through which individual foraging strategies m

105 have identified at least 30 AF loci, but the mechanisms through which individual variants lead to alt

106 We reveal a novel mechanism through which infection with an extracellular

107 The mechanisms through which infiltrating lymphocytes cause

108 of roles are most effective and the specific mechanisms through which influence is achieved.

109 Here we review the mechanisms through which interferon signatures and inter

110 suppression of calbindin by DeltaFosB is one mechanism through which intermittent seizures drive pers

111 tients and the larger healthcare system, the mechanism through which it functions is less clear.

112 The platelet surface target of MMP-2 and the mechanism through which it primes platelets to respond t

113 tor of PG synthesis during division, but the mechanisms through which it acts are unknown.

114 hila melanogaster strains, but the molecular mechanisms through which it does so have remained elusiv

115 We aimed to understand the molecular mechanisms through which JAM-A expression regulates tigh

116 helices help guide RNA tertiary folding, the mechanisms through which junctions influence folding rem

117 This study provides insights into the mechanisms through which lineage-specific regulatory fac

118 scriptome profiling, we identified molecular mechanisms through which LMP2A affects B cell biology.

119 We propose molecular mechanisms through which lncRNAs could regulate this sub

120 to chronic physiologic stress as a potential mechanism through which lower parental education level l

121 n in the bone marrow and they reveal a novel mechanism through which LOX-driven IL6 production by col

122 These findings define a mechanism through which macrophages promote therapeutic

123 However, mechanisms through which macrophages sense and respond t

124 h and connectivity are thought to be a major mechanism through which many gene variants cause neurolo

125 posure are also hypothesized to underlie the mechanism through which maternal stress may disrupt feta

126 se studies will give insights into potential mechanisms through which maternal Cd exposure impacts ca

127 ppreciation and understanding of the diverse mechanisms through which metabolites and metabolic signa

128 rnal viral infection, presenting a potential mechanism through which MIA impacts prenatal brain devel

129 However, the molecular mechanisms through which MIA imparts risk remain poorly

130 These data define a cellular mechanism through which microglia regulate experience-de

131 ased vectors as a model, we investigated the mechanisms through which microglia recognize and respond

132 ed that highly chiral cell shape is a robust mechanism through which microscale swimmers can achieve

133 Therefore, elucidating the physiological mechanisms through which midbrain 5-HT neurons modulate

134 contextual retrieval as one plausible neural mechanism through which mindfulness-based interventions

135 Elucidation of the mechanisms through which miR-128 impairs HIV-1 replicati

136 Moreover, we focus on the emerging mechanisms through which miRNAs contribute to different

137 Our results signify that by identifying mechanisms through which mixtures of air pollutants oper

138 Ox-LDL may reflect core mechanisms through which MS components develop and progr

139 ults provide new insights into the potential mechanisms through which multiple global change factors

140 y and regulation of molecular complexes, the mechanisms through which mutations lead to disease, and

141 eate an elegant histamine-dependent feedback mechanism through which myeloid bone marrow cells restor

142 terol-rich diet and uncover a PDL1-dependent mechanism through which MZB cells use their innate immun

143 anation for GCase activation and the precise mechanism through which N370S and L444P cause Gaucher di

144 Future studies should clarify the specific mechanisms through which NAcc volume exerts its therapeu

145 Tom revolutionized our understanding of the mechanisms through which neuronal cell type identities a

146 Further elucidating the mechanisms through which NHERF1 modulates mast cell resp

147 Defining regulatory mechanisms through which noncoding risk variants influen

148 t has well-documented molecular and cellular mechanisms through which nongenetic inheritance occurs.

149 models are warranted to elucidate the neural mechanisms through which NPY influences NAc function and

150 c as compared to Ketoprofen is reported, the mechanisms through which NSAIDs cause adverse cardiovasc

151 e following lymphatic injury, suggesting one mechanism through which obesity may worsen lymphedema.

152 onal space, suggesting an "object-mirroring" mechanism through which observers could accurately predi

153 To date, the mechanisms through which omalizumab induces adverse reac

154 However, the mechanism through which orexin regulates remifentanil de

155 Pavlovian threat conditioning is an adaptive mechanism through which organisms learn to avoid potenti

156 over, our analysis revealed a drug-resistant mechanism through which overexpression of tyrosine kinas

157 w of the p53 GRN and the direct and indirect mechanisms through which p53 affects gene regulation.

158 on along the auditory pathway, we describe a mechanism through which paracrine ATP signalling enhance

159 nities to understand the splicing regulatory mechanisms through which pathogens subvert plant immunit

160 These results shed light on a novel mechanism through which PCa cells educate OCys to promot

161 We call the mutual sequestration mechanism through which pCPI-17 and MLCP interact inhibi

162 ing between communicators and receivers as a mechanism through which perceptions of value can be tran

163 of transgenic mice, pointing to a potential mechanism through which pericytic Tcf7l2 activity affect

164 Elucidating the exact mechanisms through which periodontitis and CGRP are link

165 However, the mechanism through which pertinent circuits are selected

166 C1alpha is known to bind and activate LRH-1, mechanisms through which PGC1alpha changes LRH-1 conform

167 ents are necessary to unravel the underlying mechanisms through which phages drive the composition an

168 lthough we have not identified the molecular mechanism through which PKD regulates viral replication,

169 ct ecosystem processes, and reveal a further mechanism through which plants will shape ecosystem resp

170 However, the mechanisms through which plants respond to salt exposure

171 ngs identify key hypoxia-regulated molecular mechanisms through which PMNs directly induce tumor cell

172 ulation of metabolic circuitry and provide a mechanism through which POMC neurons could be inhibited,

173 mice, and they likely are a key part of the mechanism through which positive emotions trigger catapl

174 One mechanism through which presence/absence variation can a

175 By disambiguating the mechanisms through which prey perceive risk and incorpor

176 bone marrow stromal cells (BMSCs) as a novel mechanism through which primary tumor-derived exosomes p

177 osed to be the result of disturbances in the mechanisms through which prior information influences pe

178 positively affect IBS symptoms, although the mechanisms through which probiotics exert their benefici

179 Mechanisms through which proteases recognize their subst

180 ften functionally critical rigid sites, is a mechanism through which proteins can rapidly evolve.

181 We also introduce the mechanisms through which proteins called Smads act as in

182 omoting neuropeptide expression, revealing a mechanism through which proteostatic pathways can affect

183 utlining potential biological and behavioral mechanisms through which psychosocial stress may influen

184 The result is a mechanism through which Rab35 and ARF6 cooperatively and

185 gene for depression and offer insights into mechanisms through which RCL1 may be relevant for depres

186 nsulin resistance have emerged, however, the mechanism through which reduced autophagy impairs insuli

187 Here we identify mechanisms through which reduced ANK3 exon 1b isoform ex

188 esses our current knowledge of the different mechanisms through which retrotransposons might influenc

189 These findings reveal the cellular mechanism through which ROCs form the wound epidermis an

190 y macrophages and neutrophils is the primary mechanism through which S. aureus infection is controlle

191 E (ApoE)(-/-) mice, we sought to search the mechanism through which SCAP signaling affects VSMC foam

192 gand-induced dimerization is the predominant mechanism through which secreted proteins activate cell

193 Here we report an epigenetic mechanism through which seizures chronically suppress hi

194 Taken together, our results provide a mechanism through which serial dependence can promote th

195 ll-size homeostasis; however, the underlying mechanism through which size is controlled is poorly und

196 We sought to determine the mechanisms through which skin injury, dysbiosis, and inc

197 t that accelerated biological aging may be a mechanism through which sleep influences risk.

198 ew first presents a framework describing the mechanisms through which SNAP policy can influence publi

199 Understanding mechanisms through which social disadvantage becomes bio

200 cells, illustrating bidirectional regulatory mechanisms through which sodium and the immune system co

201 These findings may be key mechanisms through which spindle nesting supports memory

202 vely, these data describe a novel regulatory mechanism through which STAT3 and the Ikaros zinc finger

203 Here, we describe the possible mechanisms through which STAT3 and STAT1 GOF mutations m

204 nation with a MEK inhibitor, providing a new mechanism through which statin treatment may impact PDAC

205 icle in Cell, Fan et al. demonstrate a novel mechanism through which stress drives mitochondrial frag

206 ostatic load; (c) some of the key biological mechanisms through which stress impacts health, such as

207 ays through whole-brain networks, to discuss mechanisms through which stress may influence anhedonia.

208 fluence health-related outcomes; to identify mechanisms through which successful programmes work; and

209 The specific mechanisms through which such extremes and climate regim

210 Our results reveal a novel mechanism through which symbionts can benefit their host

211 However, the exact mechanism through which synapses can rapidly recruit new

212 ether, these findings highlight two distinct mechanisms through which t-ASPP2 promotes ILC initiation

213 understanding of these diseases, the direct mechanism through which tau contributes to neurodegenera

214 tabolism, determining the pathophysiological mechanisms through which TDP-43 mediates neurodegenerati

215 Our results shed light into the mechanism through which the catalyst architecture determ

216 e results delineate an epigenomic regulatory mechanism through which the circadian clock governs skel

217 been fully resolved, relates to the precise mechanism through which the energy absorbed through plas

218 onal signalling circuit provides a selective mechanism through which the enteric nervous system and i

219 in gene expression MSK1, represents a prime mechanism through which the external environment has an

220 However, the mechanism through which the gustatory system senses ther

221 ell-to-cell adhesion and communication, as a mechanism through which the inflammatory response facili

222 The molecular mechanism through which the interaction of a clonotypic

223 alogs, this pathway may be part of a broader mechanism through which the microbiome serves its key fu

224 ant, but not wild-type, PDGFRA, suggesting a mechanism through which the oncogenic activity of the mu

225 Overall, our results demonstrate a mechanism through which the phase stability of a liquid

226 hese events on corticospinal excitability, a mechanism through which the primary motor cortex control

227 In summary, we have identified a novel mechanism through which the PRMT5/WDR77 complex maintain

228 Our findings reveal a conserved mechanism through which the spatiotemporal pattern of ti

229 Though DBS is effective for treating ET, the mechanism through which the therapeutic effect is obtain

230 kine-induced IKKbeta signaling, suggesting a mechanism through which the tumor microenvironment contr

231 isorders and help us begin to understand the mechanisms through which the 'p factor' contributes to r

232 We experimentally identify two competing mechanisms through which the A-site cation influences th

233 ext challenge consists of designing specific mechanisms through which the action of individual molecu

234 conceptual model to understand the multiple mechanisms through which the economic and public health

235 l studies have tried to reveal the molecular mechanisms through which the energy absorbed by the caro

236 Identifying biological mechanisms through which the experience of adversity eme

237 into cell biology analyses to elucidate the mechanisms through which the genetic variants operate.

238 Type 2 immunity encompasses the mechanisms through which the immune system responds to h

239 These phenomena suggest key mechanisms through which the interaction of spindles and

240 Our results provide new insights into the mechanisms through which the magnitude and plasticity of

241 lls with an incoming tsunami to identify the mechanisms through which the park protects the coast.

242 To identify potential genes and mechanisms through which the previously unreported assoc

243 putational simulations, we identify specific mechanisms through which the suppression of DG affects m

244 to their molecular structure and address the mechanisms through which their fluorescence is quenched

245 The mechanism through which these CNVs confer risk for the s

246 well as embryo development to elucidate the mechanism through which these compounds mediate oocyte d

247 The mechanism through which these copolymers induce Tregs is

248 Though the exact mechanism through which these proteins operate is still

249 The specific mechanisms through which these age-associated molecular

250 iated changes in DNA methylation, suggesting mechanisms through which these alterations might affect

251 create, adopt, and reinforce, as well as the mechanisms through which these categories contribute to

252 ges in seasonal climate, but the demographic mechanisms through which these changes affect population

253 ow, where, and when p53 binds to DNA and the mechanisms through which these events regulate transcrip

254 The cellular and molecular mechanisms through which these lineage-promoting transcr

255 tively, while also establishing the synaptic mechanisms through which these neurons exert opposing be

256 They exhibit a self-regulatory mechanism through which they act as positive/negative re

257 rfere with FcgammaR function and a potential mechanism through which they could have a sustained effe

258 he HIV-1 genome determines the magnitude and mechanism through which they inhibit the virus.

259 sure of a predicted APR, suggesting a likely mechanism through which they promote aggregation.

260 he metabolic needs of the three players, the mechanisms through which they acquire nutrients, and whe

261 mmographic features is important because the mechanisms through which they are associated with breast

262 However, the specific mechanisms through which they confer risk remain unclear

263 d in autism spectrum disorder (ASD), but the mechanisms through which they contribute to ASD pathophy

264 la mediate stimulus-reward learning, but the mechanisms through which they interact are unclear.

265 Fgfr4 is crucial for alveologenesis, but the mechanisms through which they mediate this process remai

266 e significance of deceptive defenses and the mechanisms through which they operate.

267 ulate interneuron excitability and suggest a mechanism through which this occurs in silico via differ

268 One mechanism through which this occurs is via release of ne

269 r the fibril morphologies, yet the molecular mechanisms through which this accelerated nucleation tak

270 sub-optimal motor learning, but the precise mechanisms through which this effect occurs remain unkno

271 biota and their host, highlighting potential mechanisms through which this environment influences cen

272 While there are a variety of mechanisms through which this genetic exchange can take

273 relevant factors is debunking depends on the mechanisms through which this influence occurs.

274 To further investigate the mechanisms through which this locus affects CHD risk, we

275 llular sites of action of this receptor, the mechanisms through which this mediator controls the expr

276 rganism D. melanogaster to define the neural mechanisms through which this occurs.

277 There are four mechanisms through which this step could take place: oxi

278 etics underscore the importance of TIN2, the mechanism through which TIN2 regulates telomere length r

279 The mechanism through which tinnitus affects attention is un

280 the progression of glaucoma but neither the mechanisms through which TM cells sense pressure nor the

281 rtainty remains in directly interpreting the mechanisms through which traits influence performance in

282 hms in body temperature suggest a biological mechanism through which transits of one of the moon's se

283 ified conserved sites of proton binding, the mechanism through which transport is coupled to proton m

284 Our findings reveal mechanisms through which type I IFNs cause nociceptor se

285 These results provide a potential mechanism through which UPEC contributes to bladder canc

286 In this study, we investigated the mechanisms through which uric acid selectively lowers hu

287 We aim at understanding the molecular mechanisms through which VEC triggers the expression of

288 ty of brain regions; and (ii) understand the mechanism through which verubecestat might cause hippoca

289 Finally, we identify the molecular mechanism through which vICA acts, demonstrating the cen

290 Our work reveals a mechanism through which viral infections cause heightene

291 hlights the diversity of plausible molecular mechanisms through which viral variation affects clinica

292 These data provide a novel mechanism through which VS information processing could

293 ther, our findings reveal novel, overlapping mechanisms through which VTA Cav1.3 mediates cocaine-rel

294 tic ADAMTS13 deficiency, we investigated the mechanism through which VWF modulates complement and its

295 iron oxyhydroxide, this study highlights key mechanisms through which water vapor (i) adsorbs and (ii

296 This provides a mechanism through which widely reported links between pe

297 recent results and illustrate the different mechanisms through which winter storms impact the couple

298 Here, we discuss the molecular and cellular mechanisms through which WNT signaling influences cancer

299 d pluripotent stem cells) to investigate the mechanism through which YIPF5 loss of function affects b

300 However, the underlying mechanisms through which ZIKV rapidly and explosively sp