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1 strated a hydrophobic binding pocket for the melanocortin 1 receptor.
2 uction of beta-defensin 3, an antagonist for melanocortin 1 receptor.
3 alpha-melanocyte-stimulating hormone through melanocortin 1 receptor.
4 of human skin pigmentation via action at the melanocortin-1 receptor.
5 te human skin pigmentation via action at the melanocortin-1 receptor.
6  examined for their ability to stimulate the melanocortin-1 receptor.
7 lating hormone (alpha-MSH) to the alpha-MSH-(Melanocortin-1) receptor.
8 UV-tanning pathway include sunscreen agents, melanocortin 1 receptor activators, adenylate cyclase ac
9 gon is a new, orally administered, selective melanocortin 1 receptor agonist that increases levels of
10 A la-Arg-Lys-Leu peptide resulted in a 60 nM melanocortin-1 receptor agonist that is 100-fold selecti
11 line variants in MC1R, the gene encoding the melanocortin-1 receptor, and sun exposure increase risk
12                                          The melanocortin-1 receptor binding affinities of the peptid
13                                          The melanocortin-1 receptor-binding affinity of DOTA-Nle-Cyc
14 he interleukin-1 receptor antagonist and the melanocortin-1 receptor, further adding to the picture.
15                                          The melanocortin 1 receptor gene (MC1R) is responsible for n
16                     Germline variants in the melanocortin 1 receptor gene (MC1R) might increase the r
17     We examined self-reported phenotypes and melanocortin 1 receptor gene (MC1R) variants in relation
18                                          The melanocortin 1 receptor gene is a main determinant of hu
19 variants in a low-penetrance gene, MC1R, the melanocortin 1 receptor gene, increase melanoma risk to
20 odel, with a focus on indoor tanning and the melanocortin 1 receptor gene, MC1R.
21 utional DNA for nine common polymorphisms in melanocortin-1 receptor gene (MC1R).
22 n genes and discovered four mutations in the melanocortin-1-receptor gene, Mc1r, that seem to be resp
23         Common genetic variants in the MC1R (melanocortin 1 receptor) gene, which determines skin and
24  test experimentally the association between melanocortin 1 receptor genotype and melanoma susceptibi
25 hlight the molecular mechanisms by which the melanocortin 1 receptor genotype controls genomic stabil
26 al response to ultraviolet radiation and the melanocortin 1 receptor genotype.
27 ivity and receptor selectivity for the human melanocortin 1 receptor (hMC1R) (IC(50) = 17 nM).
28                      Activation of the human melanocortin 1 receptor (hMC1R) expressed on melanocytes
29 ng chimeric receptor constructs of the human melanocortin-1 receptor (hMC1R), a receptor that is not
30 ple for the use of phage displaying multiple melanocortin-1 receptor-homing peptides for the pretarge
31                                          The melanocortin 1 receptor is a key genetic determinant of
32                                          The melanocortin-1 receptor is expressed only on melanocytes
33 ssfully achieved as well as the synthesis of melanocortin-1 receptor (MC-1R) agonist and vesicular ac
34          alpha-MSH signals by binding to the melanocortin-1 receptor (MC-1R) and elevating cyclic AMP
35  in human skin and the effect of POMC on the melanocortin-1 receptor (MC-1R) and melanocyte regulatio
36                                          The melanocortin-1 receptor (MC-1R) is a G-protein-coupled r
37                                          The melanocortin 1 receptor (MC1-R) is expressed by monocyte
38                                              Melanocortin 1 receptor (MC1-R) is widely expressed in m
39 nd includes an endogenous internal control - melanocortin 1 receptor (MC1R) - targeting the equid gen
40 ulating hormone (alpha-MSH) that function as melanocortin 1 receptor (MC1R) agonists.
41 timulating hormone (MSH), which binds to the melanocortin 1 receptor (Mc1r) and induces an activation
42 plicate previously known associations in the melanocortin 1 receptor (MC1R) and tyrosinase (TYR) loci
43 s based on the affinity between cell surface melanocortin 1 receptor (MC1R) antigen and anti-MC1R ant
44  in red-haired mice resulting from a loss of melanocortin 1 receptor (MC1R) function and found that t
45 tely 6.6-kb region located upstream from the melanocortin 1 receptor (MC1R) gene and containing its p
46 an association between variants in the human melanocortin 1 receptor (MC1R) gene and red hair and fai
47                              Variants of the melanocortin 1 receptor (MC1R) gene are common in indivi
48                             Mutations in the Melanocortin 1 receptor (Mc1r) gene contribute to pigmen
49  available data suggest that variants of the melanocortin 1 receptor (MC1R) gene may predict greater
50                                              Melanocortin 1 receptor (MC1R) gene variants alter pigme
51                 Here, we show that the human melanocortin 1 receptor (MC1R) gene, a critical componen
52 n are disruptive variants (R alleles) in the melanocortin 1 receptor (MC1R) gene.
53 product of inactivating polymorphisms in the melanocortin 1 receptor (MC1R) gene.
54 g mechanism remains elusive, but the role of melanocortin 1 receptor (MC1R) has been implicated and w
55 , and our results suggest a new role for the melanocortin 1 receptor (MC1R) in reproductive biology.
56                                          The melanocortin 1 receptor (MC1R) is a regulator of eu- and
57                                          The melanocortin 1 receptor (MC1R) is expressed in 94% of uv
58                             Variation at the melanocortin 1 receptor (MC1R) is very common in most no
59              Reduced function alleles of the melanocortin 1 receptor (MC1R) lead to red hair, freckli
60 hypertrophic scarring (HTS) are unknown, and melanocortin 1 receptor (MC1R) loss-of-function leads to
61                                          The melanocortin 1 receptor (MC1R) mediates the tanning resp
62           However, the role of hematopoietic melanocortin 1 receptor (MC1R) signaling remains unknown
63 mmunogenic binding of cell surface biomarker melanocortin 1 receptor (MC1R) to anti-MC1R antibody.
64                                          The melanocortin 1 receptor (MC1R), a G(s) protein-coupled r
65 the yellow/red tail color that maps close to melanocortin 1 receptor (mc1r), a gene involved in pigme
66                          Loss-of-function in melanocortin 1 receptor (MC1R), a GS protein-coupled rec
67                                          The melanocortin 1 receptor (MC1R), a GS-coupled receptor th
68 n studied to date, two key genes, Agouti and Melanocortin 1 receptor (Mc1r), encode a ligand-receptor
69  most vertebrates, two key genes, Agouti and Melanocortin 1 receptor (Mc1r), encode a ligand-receptor
70 Skin pigmentation, which is regulated by the melanocortin 1 receptor (MC1R), is an effective protecti
71 olor mutations, only one gene in humans, the melanocortin 1 receptor (MC1R), is known to account for
72 show that a loss-of-function mutation in the melanocortin 1 receptor (Mc1r), recognized as a Mendelia
73    The curent study found high expression of melanocortin 1 receptor (MC1R), the receptor for a-MSH,
74    The curent study found high expression of melanocortin 1 receptor (MC1R), the receptor for alpha-M
75  the melanocortin 4 receptor, but not to the melanocortin 1 receptor (MC1R), whereas ASIP binds with
76 multiple copies of a specific ligand for the melanocortin 1 receptor (MC1R), which has been evaluated
77                                          The melanocortin 1 receptor (MC1R), which signals through cA
78 nic genes that are normally activated by the melanocortin 1 receptor (Mc1r)-cyclic adenosine monophos
79 und that McSCs migrate to the epidermis in a melanocortin 1 receptor (Mc1r)-dependent manner and diff
80 of whom contain functional disruption of the melanocortin 1 receptor (MC1R).
81 roduction is mediated by the Galphas-coupled melanocortin 1 receptor (MC1R).
82 des were observed in mice with nonfunctional melanocortin 1 receptors (MC1R), ruling out the possibil
83                                              Melanocortin-1 receptor (MC1R) and very late antigen-4 (
84                                              Melanocortin-1 receptor (MC1R) and very late antigen-4 (
85 he identification of a novel peripheral skin melanocortin-1 receptor (MC1R) antagonist.
86  indicated that SHU9119 is an agonist at the melanocortin-1 receptor (MC1R) but an antagonist at the
87 atural variation in the coding region of the melanocortin-1 receptor (MC1R) gene is associated with c
88                    Sequence variation in the melanocortin-1 receptor (MC1R) gene is associated with r
89 en somatic BRAF-mutant melanoma and germline melanocortin-1 receptor (MC1R) gene status.
90 mone receptor (MSHR), the protein product of melanocortin-1 receptor (MC1R) gene, leads to the synthe
91  a region of chromosome 11 that includes the Melanocortin-1 receptor (MC1R) gene, which regulates col
92 s perfectly associated with variation in the melanocortin-1 receptor (MC1R) gene.
93 , charge-changing amino acid mutation in the melanocortin-1 receptor (Mc1r) in beach mice, which decr
94                                          The melanocortin-1 receptor (MC1R) is a key regulator of pig
95                         Genetic variation in melanocortin-1 receptor (MC1R) is a known contributor to
96                                          The melanocortin-1 receptor (MC1R) is a seven-transmembrane
97          Inherited genetic variations in the melanocortin-1 receptor (MC1R) responsible for human red
98             Aiming at the design of specific melanocortin-1 receptor (MC1R) targeted imaging probes,
99                             We sequenced the melanocortin-1 receptor (Mc1r) to study the genetic basi
100        Skin cancer risk information based on melanocortin-1 receptor (MC1R) variants could inform pre
101                                 Some genetic melanocortin-1 receptor (MC1R) variants responsible for
102                     The individuals carrying melanocortin-1 receptor (MC1R) variants, especially thos
103                                          The melanocortin-1 receptor (MC1R), a G-protein-coupled rece
104 didate gene for this color difference is the melanocortin-1 receptor (MC1R), a key regulator of melan
105 y cAMP-dependent signaling downstream of the melanocortin-1 receptor (MC1R).
106 gmentary within the normal population is the melanocortin-1 receptor (MC1R).
107  chimerical receptor constructs of the human melanocortin-1 receptor (MC1R; a receptor that is not in
108 have been identified, but only one gene, the melanocortin 1 receptor (MCR1), has so far been identifi
109 tation process may not necessarily involve a melanocortin-1 receptor-mediated mechanism.
110                                              Melanocortin 1 receptor polymorphisms correlate with ski
111 fy dysregulation of the pro-opiomelanocortin-melanocortin 1 receptor (POMC-MC1R) axis as a common fea
112  a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical ba
113 ily, examining their potential as ligands of melanocortin-1 receptor, through selection based on thei
114 majority of redheads sequenced (89%) had two melanocortin 1 receptor variants previously found to be
115 cyte cultures naturally expressing different melanocortin 1 receptor variants to alpha-melanocortin a
116  whom were also screened for the presence of melanocortin 1 receptor variants.
117 ine efficacy have been attributed in part to melanocortin-1 receptor variants.
118 -talk between the mu-opiate receptor and the melanocortin-1 receptor, we conclude that the beta-endor
119  identified several new potential ligands of melanocortin-1 receptor, which may have implications for
120 ng via cell-surface signaling by binding the melanocortin 1 receptor with the antagonist agouti-signa

 
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