ライフサイエンスコーパス: membrane

1 he insertion of AMPARs into the postsynaptic membrane.

2 phila bacteria, which requires ERGIC-derived membrane.

3 n allograft and covered with a nonresorbable membrane.

4 toxicity by its interaction with the neuron membrane.

5 i) complex reconstituted into a phospholipid membrane.

6 oper architecture of the mitochondrial inner membrane.

7 tors are rapidly recycled back to the plasma membrane.

8 chaotropes on the hydrophobic portion of the membrane.

9 sically disrupting the integrity of the cell membrane.

10 ate to be less than 20 monomers long, to the membrane.

11 ds found on the cytosolic side of the plasma membrane.

12 )-activated potassium channels to the plasma membrane.

13 ering the expression of VDAC-1 in the plasma membrane.

14 man immune receptor CD59 in a nanodisc model membrane.

15 th the outer side of the mitochondrial inner membrane.

16 detect His-tagged proteins in PAGE and blot membranes.

17 dual cell cytoplasm and cytotrophoblast cell membranes.

18 ity to rapidly internalize across biological membranes.

19 s, including 4 brackish water and 2 seawater membranes.

20 Lewy bodies rich in vesicles and other lipid membranes.

21 clotides interact with and permeabilize cell membranes.

22 ing lateral interactions between proteins on membranes.

23 train EGD-e while bound to native-like lipid membranes.

24 idylethanolamine, respectively, in mammalian membranes.

25 yers in state-of-the-art nanofiltration (NF) membranes.

26 i-wetting performance of the composite Janus membranes.

27 aments are directly associated with specific membranes.

28 patoma cells and along LD-centric autophagic membranes.

29 usly to allow transfer of nucleotides across membranes.

30 sure thermostability of GP embedded in viral membranes.

31 inated remodelling of their cytoskeleton and membranes.

32 the function of the translocase of the inner membrane 23 is compromised such as in temperature-sensit

33 charomyces cerevisiae Spf1 revealed a large, membrane-accessible substrate-binding pocket that altern

34 Pore formation by membrane-active peptides, naturally encountered in innat

35 tty acid (palmitate) to lipid A by the outer membrane acyltransferase enzyme PagP occurs in immunosti

36 ic lipids that could potentially enhance the membrane affinity of the entire RBD-CRD construct.

37 on of the P and L rings is to seal the outer membrane after motor disassembly.

38 n and closed states measured on multichannel membranes also show statistically significant increases,

39 of C99, providing an example of how ordered membranes alter membrane protein structure.

40 rast, low pH did not affect the formation of membrane-anchored TNFR1-containing signaling complex (co

41 romotes rapid permeabilization of the plasma membrane and bacterial cell death.

42 accumulates in the choriocapillaris, Bruch's membrane and drusen, and can compete with FH/FHL-1 for C

43 f the receptor type found in muscle-endplate membrane and in the muscle-derived electric tissues of f

44 receptor tyrosine kinase (SRC) to the plasma membrane and promotes activation of an SRC-dependent sig

45 By simply attaching hBN-SSWC to a commercial membrane and providing power with an a.c. supply at hous

46 binding to phospholipids in both the plasma membrane and synthetic membranes, and is sufficient to i

47 stal-like structures in the bacterial plasma membrane and thereby promotes rapid permeabilization of

48 se Heinz bodies become deposited on the cell membranes and can lead to hemolysis.

49 stabilized pores that might disrupt neuronal membranes and ion homeostasis.

50 es, which induced adhesion zones between the membranes and the formation of transient fusion stalks i

51 sights into the phase separation of cellular membranes and, more generally, two-dimensional fluids on

52 endoplasmic reticulum (ER) membrane, plasma membrane, and nanodomains induced by cholera toxin B.

53 ate electrode materials, use of ion exchange membranes, and development of other sensor components, a

54 ds in both the plasma membrane and synthetic membranes, and is sufficient to induce extensive membran

55 host endomembrane system, penetrate cellular membranes, and undergo capsid disassembly to reach an in

56 of (18)F-DCFPyL PET/CT, a prostate-specific membrane antigen (PSMA)-targeted PET agent, in patients

57 Prostate-specific membrane antigen (PSMA)-targeting PET imaging is becomin

58 oxy-(18)F-DCFPyL ((18)F-JK-prostate-specific membrane antigen [PSMA]-7) has shown favorable propertie

59 tions in cellular energy metabolism and as a membrane antioxidant.

60 sensing and polymethacrylate-based reference membranes are attached covalently.

61 reatly suppressed by soluble extracts of PRF membranes as indicated by tartrate-resistant acid phosph

62 y mimic nature to fabricate patterned porous membranes as the support, so that it optimizes hydrodyna

63 interaction of the channel with a peripheral membrane-associated Ca(2+)-binding protein, likely ANXA1

64 eins from different orthopoxviruses bound to membrane-associated TNF and dampened inflammatory gene e

65 suicides, and depressed nonsuicides, plasma membrane-associated tubulin showed significant decreases

66 pid headgroups facilitates the initial, fast membrane association of the fluorophores, followed by sl

67 nomer-to-dimer transition, clear evidence of membrane association, and probable structures of prefusi

68 up 2, the integrity of the external limiting membrane at 3 months postoperatively was the only signif

69 have investigated phase separation in model membranes at the coarse-grained level, but atomistic sim

70 o have a clinically significant retrocorneal membranes at the time of graft failure.

71 ckers reduced ethanol-induced C3a/b, C4, and membrane attack complex/C5b9 formations; ROS production;

72 Curiously, BIN1 membrane binding and bending was diminished in cells whe

73 cular dynamics simulations also suggest that membrane binding of MreB double protofilaments induces a

74 rane, yet the effects of lipid mixing on the membrane biophysical properties remain poorly understood

75 Since nonapoptotic membrane blebbing is now recognized as an important regu

76 Phagocytes engulf pathogens into a membrane bound compartment called a phagosome, but what

77 d crystalized conformation to a more native, membrane-bound conformation in silico.

78 ed whether the loss or overexpression of the membrane-bound ephrin-B1 in astrocytes during postnatal

79 olling the self-organisation and dynamics of membrane-bound organelles such as the Golgi apparatus, r

80 egulatory element-binding proteins (SREBPs), membrane-bound transcription factors whose proteolytic a

81 which the first cells used simpler types of membrane building blocks and has hampered integration of

82 Platelet-rich fibrin (PRF) membranes can preserve alveolar ridge dimension after to

83 espectively, suggest routes into the central membrane cavity.

84 riability in tension sensitivity among these membrane channels.

85 ientation spectra are extremely sensitive to membrane chemical composition.

86 protonated/ionized form, considering similar membrane concentrations.

87 is an essential component of mammalian cell membranes, constituting up to 50% of plasma membrane lip

88 o calculate steric pressure as a function of membrane coverage by ENTH, validating theoretical equati

89 membranes, which introduces nonphysiological membrane curvature and composition.

90 MreB double protofilaments induces a stable membrane curvature of similar magnitude to that observed

91 family interact with ABA receptors at plasma membrane, cytosol, and nucleus, targeting them for degra

92 he plasma membrane potential and that plasma membrane depolarization blocks cellular uptake of N-acyl

93 anding of ionization that could enable novel membrane design.

94 We thus determine a trend that the membrane diffusivity drops with increased lipid packing

95 Collagen membrane discs were implanted under the scalp in diabeti

96 Treatment with Tat-A and Tat-B caused membrane disruption and pore formation in HeLa and BE(2)

97 e CD40 relocation to the detergent-resistant membrane domain and to inhibit CD40-induced phosphorylat

98 Our results demonstrate that distinct membrane domains can integrate a common signal with spec

99 g the importance of these specialized plasma membrane domains in cellular feedback via the Hippo path

100 In this study, electrospun membrane drug delivery systems consisting of the antibio

101 for bird-mediated dispersal ability of soft-membraned eggs undergoing active development.

102 ia is critical for developing anion exchange membrane electrolyzers.

103 Crystallization of membrane-embedded components within phospholipid bilayer

104 ion of MT1-MMP-laden endosomes to the plasma membrane, enabling both invadopodia outgrowth and MT1-MM

105 oach, we find that cholesterol in the target membrane enhances the efficiency of single-particle IAV

106 Our data provide evidence that the membrane enhances two dissipative pathways, one of which

107 H-2 activity, and its potency is higher in a membrane environment compared to assays performed with w

108 acterization, structures of TRPV3 in a lipid membrane environment provide unique insights into channe

109 lity of LHCII pigment-protein complexes in a membrane environment, revealing putative sites for confo

110 f predicting structural features of integral membrane enzymes.

111 individual photosynthetic complexes in grana membranes establishes a foundation that could be adapted

112 es showed that Lm128C cells exhibit elevated membrane excitability, with biophysical properties close

113 -128 in regulating gene networks that govern membrane excitability.

114 Niche cells often wrap membrane extensions around stem cell surfaces.

115 for linear elastic matrices such as basement membrane extract hydrogels (Matrigel) that allows us to

116 ired for transport-III (ESCRT-III) catalyzes membrane fission from within membrane necks, a process t

117 ages, and resulting in a gradual increase in membrane fluidity in individuals ranging from newborn to

118 These alterations are reverted when membrane fluidity is restored by a chemical fluidizer.

119 e effectiveness of P-Tris affinity nanofiber membrane for the recovery of lysozyme from complex CEW s

120 cellularly derived and biologically relevant membranes for biophysical characterization.

121 F conformational change needed to facilitate membrane fusion and virus infection, and the epitope rec

122 Whereas the process of HIV membrane fusion can be tracked by fluorescence microscop

123 ribe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two forms o

124 tion, paramyxoviruses cause a second type of membrane fusion, cell-cell fusion (syncytium formation),

125 observations describe a mechanism for gating membrane fusion.

126 rearrangements through which the HA mediates membrane fusion.

127 The long-term adjustment of thylakoid membrane grana diameter positively correlated with LHCII

128 These membranes have a multimodal porous network structure wit

129 TANGO1 has an unusual membrane helix organisation, composed of one membrane-sp

130 d clinical examination detected retrocorneal membrane in 10%, 7.5%, and 5% (P = .005), iris adhesions

131 ally tagged Rho3 is restricted to the plasma membrane in a gradient corresponding to cell polarity th

132 e report an experimental investigation of BP membrane in osmotic energy conversion and reveal how the

133 4 (GLUT4)-containing vesicles to the plasma membrane in response to insulin stimulation.

134 er a steady-state organization of the plasma membrane in resting cells that is poised to orchestrate

135 vealed that the Aster-B GRAM domain binds to membranes in a cholesterol concentration-dependent manne

136 t metallo-polyelectrolytes as anion-exchange membranes in solid-state alkaline fuel cells.

137 9 parameters to calibrate for 6 different RO membranes, including 4 brackish water and 2 seawater mem

138 revealed a built-in mechanism controlling Gc membrane insertion for fusion, pave the way for immunoge

139 ellular protease release, suggesting altered membrane integrity after the field exposure.

140 specific metabolites, while retaining their membrane integrity.

141 e tetramer is a dimer of dimers, wherein the membrane-interacting BAR surfaces are sequestered and th

142 functional surfaces to directly measure Syt1-membrane interaction and fully map the site-binding ener

143 (MD) simulations were employed to study the membrane interactions of the intrinsically disordered SH

144 ges in osmolarity but instead was induced by membrane-intercalating agents that are prevalent in the

145 calized intracellularly and at the cell wall-membrane interface, implying the presence of reducing-en

146 cal explanation for the formation of nuclear membrane invaginations.

147 main of TrkB in the cytosol or on the plasma membrane is able to induce the activation of downstream

148 The membrane is also highly vulnerable to many types of pert

149 extracellular to the cytoplasmic side of the membrane, is rate limiting to transport.

150 transfer (IT) processes across ion-selective membranes (ISMs) with thicknesses in the nanometer order

151 a(+) K(+) -ATPase activity using sarcolemmal membranes isolated from hindlimb muscle of control (CON,

152 nductance channel in the inner mitochondrial membrane known as the PTP (permeability transition pore)

153 indicated that the presence of RBD near the membrane led to a local enrichment of anionic lipids tha

154 LLPS) of proteins underlies the formation of membrane-less organelles.

155 itro, selumetinib downregulated cellular and membrane levels of PD-L1 in tumor cells by 50% as measur

156 ed fatty acids are rapidly incorporated into membrane lipids, inducing a reduction in membrane packin

157 membranes, constituting up to 50% of plasma membrane lipids.

158 Kir2.2 has multiple interactions with plasma membrane lipids: Phosphatidylinositol (4, 5)-bisphosphat

159 ercise-induced activation of AMPK and plasma membrane localization of the GLUT4 glucose transporter i

160 ggest the participation of the C terminus in membrane localization, which is generally overlooked and

161 implanted collagen membranes, which reduces membrane longevity.

162 igid" dendronized side chains to enhance the membrane lytic property.

163 at can facilitate a general understanding of membrane-mediated ligand binding.

164 Concomitantly, membrane morphology and lipid packing became disrupted.

165 Stimulation of the membrane Na(+)-K(+) pump should lower Na(+) concentratio

166 Our results show that membrane necks become diffusion barriers.

167 -III) catalyzes membrane fission from within membrane necks, a process that is essential for many cel

168 nd Ca(V)1.2 into nanocomplexes at the plasma membrane of human and mouse arterial myocytes.

169 meshwork that uniformly underlies the plasma membrane of the entire cell.

170 questered to the inner leaflet of the plasma membrane of the healthy eukaryotic cells.

171 e of nascent virus particles from the plasma membranes of infected cells.

172 ies on the physical disruption of the plasma membrane once the peptide targets specific phospholipids

173 lysozyme adsorption efficiency of the P-COOH membrane operating in a stirred cell contactor (Millipor

174 recycling endosome rather than to the plasma membrane, our findings reveal the complexity of recruitm

175 aortic balloon pump in 2, and extracorporeal membrane oxygenation and Impella CP in 1.

176 al membrane oxygenation in 2, extracorporeal membrane oxygenation and intra-aortic balloon pump in 2,

177 ients (67%), Impella CP in 2, extracorporeal membrane oxygenation in 2, extracorporeal membrane oxyge

178 ytopenia is already common at extracorporeal membrane oxygenation initiation.

179 patient per group (venovenous extracorporeal membrane oxygenation or venoarterial extracorporeal memb

180 red with 95 in 459 venovenous extracorporeal membrane oxygenation patients (odds ratio, 2.35; 95% CI,

181 cations in 6,124 venoarterial extracorporeal membrane oxygenation patients compared with 95 in 459 ve

182 The median extracorporeal membrane oxygenation support time was 96 hours (interqua

183 Extracorporeal membrane oxygenation survivors' physical quality of life

184 The use of extracorporeal membrane oxygenation to support critically ill, poisoned

185 e oxygenation or venoarterial extracorporeal membrane oxygenation) had surgery before extracorporeal

186 avirus 2 requiring venovenous extracorporeal membrane oxygenation.

187 ry support using venoarterial extracorporeal membrane oxygenation.

188 ygenation) had surgery before extracorporeal membrane oxygenation.

189 nto membrane lipids, inducing a reduction in membrane packing.

190 In a mainstream proton exchange membrane (PEM) fuel cell, platinum-group-metal (PGM)-bas

191 gs demonstrate that positioning of the virus membrane penetration site couples two decisive infection

192 h microbubbles can efficiently increase cell membrane permeability resulting in enhanced tissue distr

193 ondrial DNA depletion or mitochondrial outer membrane permeabilization blockage via BCL2 overexpressi

194 We conclude that outer membrane perturbation can be sensed by P. aeruginosa to

195 ophospholipids from phospholipids, including membrane phospholipids from cells and bacteria and surfa

196 hen comparing the endoplasmic reticulum (ER) membrane, plasma membrane, and nanodomains induced by ch

197 gulated through crosstalk between the plasma membrane (PM), where most cellular cholesterol resides,

198 ysical analysis of isolated mammalian plasma membranes (PMs).

199 re less intrusive and had a milder effect on membrane pore structure.

200 The resulting short-term memory of the membrane potential allows to generate persistent firing

201 athy, restored cardiac myocyte mitochondrial membrane potential and flavoprotein oxidation, and preve

202 lycolysis is required to maintain the plasma membrane potential and that plasma membrane depolarizati

203 These discoveries argue that bacterial membrane potential dynamics deserve more attention.

204 erapeutics sensitized cells to mitochondrial membrane potential loss and apoptosis.

205 chemical probes that regulate mitochondrial membrane potential, adenosine 5'-triphosphate contents,

206 AMP-induced pores, depolarizes the bacterial membrane potential, and impairs membrane recovery.

207 retained a normal KCNQ4 current and resting membrane potential.

208 odeling deficits and decreased mitochondrial membrane potential; a subset had increased resting mitoc

209 te (Fe(3)S(4)), enveloped by a lipid bilayer membrane, produced by magnetotactic bacteria.

210 of a C. trachomatis recombinant major outer membrane protein (rMOMP) vaccine to elicit cross-serogro

211 inase (JNK) signaling, induced by the latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV).

212 receptor (SNARE) molecule vesicle-associated membrane protein 4 (VAMP4) as a key component of the mac

213 ytophilum surface protein (Asp14), and outer membrane protein A (OmpA) are essential for optimal bact

214 Membrane protein biogenesis in the endoplasmic reticulum

215 largest and most pharmacologically targeted membrane protein family.

216 vivo interactors of AtGET1 and identified a membrane protein of unknown function with low sequence h

217 strongly suggest that extensive erythrocyte membrane protein phosphorylation and ubiquitination are

218 activation requires the cholesterol-sensing membrane protein Scap.

219 ng an example of how ordered membranes alter membrane protein structure.

220 Motivated by the fact that in vitro membrane protein studies often require additives such as

221 ability data, and in vitro tests using three membrane protein targets with 7, 11 and 16 transmembrane

222 The Na(+)/I(-) symporter (NIS), the plasma membrane protein that actively transports I(-) (stoichio

223 s anionic phospholipids through an extensive membrane:protein interface.

224 tant low-resolution information for integral membrane proteins (IMPs), challenging targets for struct

225 ment depends upon interactions between viral membrane proteins and tegument proteins that encrust cap

226 resolution structures of large complexes and membrane proteins are determined regularly.

227 Alpha-helical integral membrane proteins contain conserved sequence motifs that

228 st membrane proteome revealed that polytopic membrane proteins have relatively low ribosome abundance

229 A large number of newly synthesized membrane proteins in the endoplasmic reticulum (ER) are

230 ptors (GPCRs) are a large family of integral membrane proteins responsible for cellular signal transd

231 re-emptive pathway that reduces synthesis of membrane proteins that have failed to properly assemble

232 holipid bilayers with two different types of membrane proteins, CorA and tissue factor (TF).

233 A particular challenge, especially for membrane proteins, is preserving noncovalent interaction

234 n about the mechanisms required for assembly membrane proteins.

235 provides a realistic pH-dependent model for membrane proteins.

236 n of translation efficiency across the yeast membrane proteome revealed that polytopic membrane prote

237 nt engagement with the envelope glycoprotein membrane-proximal external region (MPER) results in robu

238 e devices (high volume) or plasma separation membranes (PSM) coupled with lateral flow tests (low vol

239 us on the assembly and function of the inner membrane pumps.

240 energic receptor b2 (Adrb2) and Progesterone membrane receptor component 1 (Pgrmc1), while longer Abe

241 Stimulation of plasma membrane receptor tyrosine kinases (RTKs), such as the e

242 eptors (GPCRs) comprise the largest group of membrane receptors in eukaryotic genomes and collectivel

243 single-molecule FRET assays with a nanodisc membrane reconstitution system to investigate the confor

244 he bacterial membrane potential, and impairs membrane recovery.

245 of microstructured poly(vinylidene fluoride) membrane, referred to as a "meta-skin" insulator, which

246 uired for transport (ESCRTs) mediate diverse membrane remodeling events.

247 assemble in the cytoplasm and at the plasma membrane, respectively.

248 lipophilic probes transiently bound to lipid membranes, revealing that Nile red's (NR) orientation sp

249 nd bending was diminished in cells where the membrane's charge was experimentally reduced.

250 rocatalytic oxygen reduction on the cathodic membrane side and subsequently terminated by H(2)O(2) ox

251 rminated by H(2)O(2) oxidation on the anodic membrane side, is crucial for (1)O(2) generation.

252 g mainly in proteolytically cleaved form, as membrane-spanning C-terminal fragments of the proteins.

253 E217G, located in the loop region of CFTR's membrane-spanning domain.

254 membrane helix organisation, composed of one membrane-spanning helix (TM) and another that penetrates

255 maturation and function depend on the seven-membrane-spanning inactive rhomboid-like proteins 1 and

256 f storage proteins led to the elaboration of membrane stacks enriched with oleosin (sixfold higher pr

257 e that melatonin can have a strong effect on membrane structure and physical properties, which may pr

258 itude more elastic than the classical plasma membrane suggesting a physical explanation for the forma

259 ACA showed an amorphous protein layer on the membrane surface.

260 nistic differences of the MA-mediated plasma membrane targeting of the B-type mouse mammary tumor vir

261 tion of protein substrates, often to mediate membrane targeting.

262 Membrane tension pores determine organelle dynamics and

263 binding to neurons by interacting with lipid membranes (termed lipid-binding loop [LBL]).

264 ell, Kong et al., 2020 identify members of a membrane-tethered ubiquitin complex that attenuates Hedg

265 ee small plastidial proteins of the envelope membrane that interact with the alpha-carboxyltransferas

266 ed Ca(2+) channel of the inner mitochondrial membrane that regulates cellular metabolism.

267 abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids i

268 in the regularly spaced paired-pits and pit membranes that hydraulically connect neighboring xylem e

269 At high peptide concentrations in the membrane, the (19)F-(13)C distance data indicate three c

270 To survive within this enveloping membrane, the organism must take in nutrients, secrete w

271 ositides 1 (Grp1) is recruited to the plasma membrane through its pleckstrin homology (PH) domain tha

272 y is the temporary creation of pores in cell membranes through a phenomenon called sonoporation by hi

273 that destabilizes the rigidity of the outer membrane to exert pleiotropic effects on the functionali

274 unit cells that are linked via a shared wing membrane to form this metamaterial, and collectively the

275 ated by BDNF and its receptors at the plasma membrane to modulate BDNF-dependent gene expression and

276 ased focal adhesion complexes link the glial membrane to the extracellular matrix, but little is know

277 and photosynthetically functional thylakoid membranes to be able to understand its structural respon

278 nt degree of flexibility to tailor microbial membranes to meet specific needs.

279 is has prompted the development of synthetic membranes to study lipid-lipid interactions in vitro, al

280 ons affecting the competency of the basement membranes to which they contribute.

281 Arfs control distinct steps in intracellular membrane traffic, and one of the Arf-activating proteins

282 se-causing amastigotes but not for flagellar membrane trafficking.

283 ighlight the influence of nanoconfinement on membrane transport properties and provide enhanced funda

284 development of gold nanoparticles (Np) as a membrane-traversing delivery vehicle to carry PMI for an

285 Cryo-ET reveals how the shape of the helical membrane tube arises from the assembly of two distinct b

286 ranes, and is sufficient to induce extensive membrane tubulations.

287 s can be observed to interact transiently on membrane tubules in hepatoma cells and along LD-centric

288 h serially diluted antibiotics with a novel, membrane-type micromixer consisting of two circular micr

289 pid compositions of the different organellar membranes vary, their surface charges are similarly expe

290 and Atg8-play in the formation of the double-membrane vesicle autophagosome, which is the functional

291 Giant plasma membrane vesicles (GPMVs) are a widely used experimental

292 design next-generation fouling-resistant RO membranes via structural optimization: first, a smooth s

293 The ZIF-8 membrane was prepared on a commercial flat-sheet ceramic

294 Human Nuclear Lipid Membranes were at least two orders of magnitude more ela

295 Placental chorioamniotic membranes were studied using RNA microarray and immunohi

296 and reconstituting viral fusion to synthetic membranes, which introduces nonphysiological membrane cu

297 mmation in and around the implanted collagen membranes, which reduces membrane longevity.

298 that have the same helical path but bind the membrane with different interfaces.

299 Starting from the plasma membrane with the recognition of microbe-associated mole

300 the unique composition of lipids within the membrane, yet the effects of lipid mixing on the membran