ライフサイエンスコーパス: membrane current

1 BA and picrotoxin induced a large rebound of membrane current.

2 ed with VMD greatly reduces or abolishes the membrane current.

3 e laser-induced fluorescence did not evoke a membrane current.

4 CH, histamine failed to induce an additional membrane current.

5 s were measured by patch-clamp recordings of membrane current.

6 3+/-12 nmol/L after reoxygenation) or evoked membrane current.

7 rrent at voltages where it dominates the net membrane current.

8 the [Ca2+]i transients and [Ca2+]i-activated membrane current.

9 a capsazepine-sensitive outwardly rectifying membrane current.

10 ediated membrane current and Cav1.2-mediated membrane current.

11 inhibited NMDA-evoked, but not AMPA-evoked, membrane currents.

12 temporal heterogeneity of calcium-activated membrane currents.

13 ined the effects of arachidonic acid (AA) on membrane currents.

14 ting membrane potential or endogenous oocyte membrane currents.

15 ed corresponding oscillations in [Ca2+]m and membrane currents.

16 Bulk particles did not modify the plasma membrane currents.

17 directly by gel shift assays and changes in membrane currents.

18 ing in such processes may target two or more membrane currents.

19 is attributable to the interplay of several membrane currents.

20 ies and demonstrates the strong influence of membrane currents.

21 ROS production also decreased AVP-stimulated membrane currents.

22 cysteine resulted in small or no appreciable membrane currents.

23 and recorded resulting ATP and BzATP-evoked membrane currents.

24 pine (1 microM) reduced the capsaicin-evoked membrane current (6/6) and depolarization (7/7 responder

25 er) increased flavoprotein oxidation but not membrane current; a 10-fold higher concentration recruit

26 Membrane current abnormalities have been described in hu

27 coupling in guinea-pig ureter, by measuring membrane currents, action potentials, intracellular [Ca2

28 of [Ca2+]i (fluo-3-acetoxymethyl ester) and membrane currents/action potentials (patch-clamp) in iso

29 yristate 13-acetate (PMA) increased the mean membrane current activated by a low concentration of cap

30 polarization was caused by a Cl(-)-selective membrane current activated by flow independently of the

31 It was attributed to a regenerative membrane current, active at the resting potential in sen

32 Slowly emerging membrane currents after theta burst stimulation are sens

33 a(2+) content (measured from caffeine-evoked membrane currents) alternated in phase with the alternan

34 Membrane current analysis showed that OH cell firing inc

35 aneous, high time-resolution measurements of membrane current and Ca(2+) fluorescence.

36 g(2+) ([Mg(2+)](o)) inhibited TRPV3-mediated membrane current and calcium influx.

37 rallel reduction in Na/Ca exchanger-mediated membrane current and Cav1.2-mediated membrane current.

38 toKATP channel in simultaneous recordings of membrane current and flavoprotein fluorescence.

39 cordingly, Abeta25-35 peptide also increased membrane current and permeability, as well as intracellu

40 rs with a significantly greater latency than membrane current and potential changes attributable to A

41 directional photomodulation of Purkinje cell membrane current and spike-firing rate.

42 a specific PIEZO1 agonist, activates a small membrane current and thereby triggers beta-cell electric

43 immunostaining and patch clamp recordings of membrane current and voltage, we identified all three SK

44 The interaction between such altered membrane currents and a changed neurohumoral milieu crea

45 increase in large conductance mitochondrial membrane currents and a decrease in bioenergetic efficie

46 Protein levels (Western blot), membrane currents and action potentials (patch clamp), a

47 Membrane currents and action potentials were recorded us

48 ulated dopamine release induces slow outward membrane currents and an associated hyperpolarization re

49 though the circadian modulation of intrinsic membrane currents and biochemical signaling have been ex

50 re, we modified the cell EP by changing both membrane currents and calcium handling.

51 Proton-evoked membrane currents and calcium influx through hTRPA1 occu

52 rug-induced changes in parameters describing membrane currents and contractile machinery close to ran

53 Here, we show that membrane currents and dendritic Ca(2+) signals evoked by

54 endolysosomal Ca(2+) stores activates inward membrane currents and depolarizes the beta cell to the t

55 al potential, suggesting a role in modifying membrane currents and GABA responses in a daily fashion,

56 in kinase C (PKC) resulting in inhibition of membrane currents and increases in intracellular Ca2+ co

57 ceding the phase 0 activation represents the membrane currents and intracellular calcium transients i

58 hemia causes profound changes in both active membrane currents and passive electrical properties.

59 Membrane currents and potential were measured by whole-c

60 Notably, however, the membrane currents and spikes of some cells in vLGN displ

61 bining patch-clamp analysis of spike firing, membrane currents and synaptic inputs with confocal imag

62 eir development, such that their basolateral membrane currents and synaptic machinery retain a pre-he

63 eir development, such that their basolateral membrane currents and synaptic machinery retain a prehea

64 cated in homeostatic regulation of intrinsic membrane currents and synaptic strength, may also regula

65 e of differential expression and function of membrane currents and transporters.

66 The model has seven voltage-dependent membrane currents and uses three Ca2+ sensors acting on

67 Membrane currents and voltage were measured in single my

68 lls showed similar levels of gain control in membrane currents and voltages and under conditions of l

69 n with thapsigargin, inhibited activation of membrane currents and volume recovery.

70 embrane voltage on absorption, fluorescence, membrane current, and membrane capacitance.

71 pipette caused significant filtering of the membrane currents, and that the filter characteristics d

72 al volume, microfluidic resistance, flexible membrane, current, and temperature--to control the deliv

73 roduce a system for simultaneously recording membrane current, applied force, and the resulting inden

74 B1 activation enhanced the heat-activated membrane current approximately 3-fold, and the enhanceme

75 -microm-long dendritic subsegment; dendritic membrane currents are not required for NMDA spike produc

76 sted that PMCA should generate a substantial membrane current as bundles expel Ca2+.

77 ts causes significant alterations in resting membrane current, as measured by whole-cell patch clamp

78 Activation of PKC did not enhance the membrane current at high concentrations of capsaicin, sh

79 nt is likely to have a greater effect on net membrane current at more positive potentials (EK channel

80 in human embryonic kidney cells and measured membrane currents before and after photo-affinity labeli

81 (AChRs) switch on/off to generate transient membrane currents (C<-->O; closed-open 'gating') and ent

82 The key insight is that membrane currents can be modeled using two scalable syst

83 ion to noxious heat stimuli by enhancing the membrane current carried by the heat- and capsaicin-gate

84 ergy delivered in each touch into excitatory membrane currents carried by mechanoelectrical transduct

85 ultaneous measurements of action potentials, membrane current, cell shortening and changes in intrace

86 and each dominantly inhibited the wild-type membrane current, consistent with the dominant nature of

87 alothane, isoflurane and sevoflurane inhibit membrane currents contributing to the ventricular action

88 ged periods - found that bCA increases total membrane current (DeltaI(m) ), which apparently supports

89 er charge transported (measured as change in membrane current, DeltaIm ).

90 Simultaneous recordings of membrane current, DeltaPsim and [Ca2+]i revealed the seq

91 activation properties of the resulting Na(+) membrane current densities revealed reduced maximum curr

92 the charge carrier, cell swelling increased membrane current density approximately 30-fold to 16.5 +

93 attenuates glucose- and sulfonylurea-induced membrane currents, depolarization, cytoplasmic Ca(2+) si

94 In addition to membrane current-driven events, a type of dendritic spik

95 s and investigated changes in the underlying membrane currents during M-F coupling.

96 luorescence photometry was used to study the membrane currents during oscillations of intracellular C

97 that the reversal potential of GABA-induced membrane currents (EGABA) was significantly more hyperpo

98 Membrane currents, electrical activity, and exocytosis w

99 ctric field gradients required to porate the membrane, current electroporation devices deliver voltag

100 subunit RNAs were injected into oocytes, and membrane currents elicited by AcCho were recorded under

101 phate receptor inhibitor, did not affect the membrane currents elicited by epidermal growth factor de

102 Therefore, the smaller amplitude of membrane currents elicited by Glu in oocytes injected wi

103 Fluoxetine (Prozac) inhibited the membrane currents elicited by serotonin (5-hydroxytrypta

104 time-dependent activation or inactivation of membrane currents elicited by voltage steps in the range

105 pressed in human embryonic kidney cells, and membrane currents evoked by ATP were recorded.

106 Using patch-clamp recordings, we found that membrane currents evoked by both menthol and innocuous c

107 evoked response, it had no direct effect on membrane currents evoked by exogenous glutamate, kainate

108 Membrane currents evoked by GABA(A) receptor activation

109 A model beginning with the membrane currents evoked by vibrissal and optogenetic dr

110 en protons and piperine were co-applied, the membrane currents evoked in piperine-sensitive TG neuron

111 3-A44V and Cx43-E227D significantly increase membrane current flow through formation of active hemich

112 By directly recording membrane currents from enlarged lysosomal vacuoles, we d

113 We recorded membrane currents from human embryonic kidney cells expr

114 icroglial cells might sense CSD by recording membrane currents from microglia in acutely isolated cor

115 We add membrane currents from the Luo-Rudy Phase II ventricular

116 The effects of PKC activation on the membrane current gated by heat, anandamide and low pH we

117 s of activation of protein kinase C (PKC) on membrane currents gated by capsaicin, protons, heat and

118 CC2 activity is critical for hyperpolarizing membrane currents generated upon the activation of gamma

119 ICa (measured as nifedipine-sensitive membrane current) had a complex multiphasic time course

120 irect application of ACh caused no change in membrane current, implying absent or otherwise dysfuncti

121 d to characterize the shear stress-sensitive membrane current in atrial myocytes using the whole-cell

122 NpHR3.0) tools to create a slow non-synaptic membrane current in bystander neurons, which matched the

123 from the patch pipette did not activate any membrane current in cells where intracellular calcium co

124 how that NAAG, but not NAA, evokes an inward membrane current in cerebellar white matter oligodendroc

125 enhances the expression of bTREK-1 mRNA and membrane current in cultured AZF cells.

126 We made whole-cell recordings of membrane current in guinea pig ganglion cells in vitro.

127 Flavoprotein fluorescence and membrane current in intact rabbit ventricular myocytes w

128 ar basis, we measured membrane potential and membrane current in mammalian ventricular myocytes by us

129 demonstrate that NMDARs transiently produce membrane current in Purkinje cells and may serve as one

130 ing cystine to cerebellar slices generated a membrane current in Purkinje cells which was abolished b

131 - channels contribute significant whole-cell membrane current in response to changes in intracellular

132 Capsaicin evokes a membrane current in trigeminal ganglion neurons that is

133 used to regulate the maximal conductances of membrane currents in an activity-dependent manner.

134 oxygen species, activated Ca(2+) influx and membrane currents in an oxidant-sensitive subpopulation

135 type Ca2+ channels, reduced constriction and membrane currents in cerebral arteries from SAH animals,

136 addition, we characterized voltage-dependent membrane currents in each type of primate retinal cell w

137 We recorded membrane currents in HEK293 cells transfected to express

138 We measured cellular fluorescence and membrane currents in individual human embryonic kidney c

139 ated patch clamp technique was used to study membrane currents in isolated rabbit corpus cavernosum s

140 he patch-clamp technique was used to measure membrane currents in isolated smooth muscle cells disper

141 ental acquisition of mature-like basolateral membrane currents in low-frequency (apical) hair cells,

142 re caused by activation of Ca(2+) influx and membrane currents in mustard oil-sensitive sensory neuro

143 l patch-clamp techniques were used to record membrane currents in neuroblastoma cells stably transfec

144 antagonist ketanserin inhibited 5-HT-induced membrane currents in OFC(PV) neurons from female and not

145 e-cell patch-clamp recording to measure cell-membrane currents in primary cultures of podocytes from

146 ions of MFQ attenuated increased macroscopic membrane currents in primary mouse keratinocytes express

147 een assessed one cell at a time by recording membrane currents in response to application of focal pr

148 Recording of membrane currents in response to ATP (whole cell and exc

149 We measured membrane currents in response to ATP and BzATP at wild-t

150 of cannabinoid (CB) receptor stimulation on membrane currents in single cells from the Syrian hamste

151 on were studied with whole-cell recording of membrane currents in single smooth muscle cells from the

152 r, failed to have any additional effect upon membrane currents in the presence of CN(-) or rotenone o

153 Membrane currents in these motor neurons oscillated in p

154 urrents, as well as GABA application-induced membrane currents, in a dose-dependent manner.

155 The reversal potential of the membrane current induced by PKC activators was approxima

156 Membrane currents induced by citrate were bigger than th

157 ained in the absence of NCX, we investigated membrane currents, intracellular Ca2+, and action potent

158 chniques were combined to examine changes in membrane currents, intracellular calcium ([Ca2+]i) and m

159 rical activity; activation of a depolarizing membrane current is also required.

160 f a complex V-associated inner mitochondrial membrane current is metabolically important and may repr

161 these components, we construct two types of membrane currents: lumped currents, which are flexible,

162 haracterized through an analysis of charging membrane currents measured with tight-seal electrodes in

163 at the level of channel mRNA expression and membrane currents (measured in voltage-clamp experiments

164 Changes in protein levels and membrane currents mirrored changes in transcript levels,

165 ithin the ventral posterior medial thalamus, membrane currents modulated by norepinephrine have been

166 of non-inactivating inward and outward tonic membrane currents modulates spatiotemporal SD susceptibi

167 ll nonselective cation current so that total membrane current near -70 mV shifted to become barely ne

168 engaged or disengaged by small shifts in net membrane current near -70 mV, as by muscarinic stimulati

169 (mGluR1 and 5) agonist reduced NMDA-mediated membrane currents, NMDA-induced cell death and up-regula

170 Low-frequency light-sensitive membrane current noise in isolated rod photoreceptors of

171 tch-clamp methods were invented, analysis of membrane current noise provided the first solid, if indi

172 ated with increases of input conductance and membrane current noise, and reversed close to 0 mV, indi

173 roduced an inward current and an increase in membrane current noise, which were accompanied by a cond

174 lectrophysiology, but efforts to measure the membrane current of intact GUVs have been unsuccessful.

175 brief flashes of light were recorded in the membrane current of isolated rods from larval tiger sala

176 The effect of extracellular K+ on membrane currents of bull frog (Rana catesbeiana) taste

177 Thus, membrane currents of oocytes of Xenopus laevis expressin

178 al impact of anaesthetic-induced blockade of membrane currents on APD and effective refractory period

179 ne simultaneously the effects of alpha-LT on membrane current or voltage, cytosolic Ca, and membrane

180 CaTs were monitored simultaneously with membrane currents or APs recorded with the patch clamp t

181 n be driven by the kinetics of voltage-gated membrane currents or by instabilities in intracellular c

182 0 microM) nor L-AP4 (0.001-50 microM) caused membrane currents or changes in the current-voltage rela

183 DHPG also elicited slow membrane current oscillations and spikelets in ET cells

184 kers, ET cell pairs exhibit synchronous slow membrane current oscillations associated with rhythmic s

185 induced significant increases in whole-cell membrane currents (P<0.01) in the presence of the coagon

186 buted to the greater duration of the outward membrane current phase, resulting in a greater outward c

187 from most mouse strains, but the basolateral membrane current profile remains unchanged.

188 d cochlea also regained a mature basolateral membrane current profile.

189 In addition, the prominent membrane current rebound when co-application of GABA and

190 f genistein, a tyrosine kinase inhibitor, on membrane currents recorded from isolated guinea pig vent

191 l activity was discernible in the whole cell membrane current recordings.

192 [Ca2+]i and membrane current recovered only after mitochondrial repo

193 suggest that the developmental plasticity of membrane currents regulating pathological rhythmicity is

194 e D2 receptors (D2Rs), though the underlying membrane currents remain unknown.

195 rent following hypotonic shock, by recording membrane current responses and cell volume changes in vo

196 e benzodiazepinones inhibited AMPA-activated membrane current responses in a manner consistent with n

197 ated the action of propofol on GABA-elicited membrane current responses of retinal bipolar cells, whi

198 y but they fail to acquire adult basolateral membrane currents, retain pre-hearing current and effere

199 hat the amiloride-sensitive component of the membrane current reversed at a potential close to the Na

200 igh [K+]o alone did not significantly affect membrane current, Rm, or Vm in AV nodal myocytes.

201 ts (perforated patch-clamp), or simultaneous membrane-current (ruptured patch-clamp) and [Ca(2+)](i)-

202 Aspartate was shown to induce a large membrane current sensitive to N-methyl-D-aspartate (NMDA

203 Recording of whole-cell membrane currents showed that four receptors operated as

204 MSCs were found to exhibit voltage-dependent membrane currents similar to the neuronally guided BMSCs

205 iated by C3aR1 receptors: it directly evoked membrane currents, stimulated basal phagocytic activity,

206 le through its influence on Ca(2+)-sensitive membrane currents such as I(Ca), I(NaCa), and I(ns(Ca)).

207 uced a cellular calcium influx and an inward membrane current that was entirely prevented by d-tubocu

208 xplained by a marked inward shift in the net membrane current that was observed in these experiments.

209 nicamycin produced gel shifts and changes in membrane currents that correlated exactly.

210 been constructed that incorporates the major membrane currents that have been isolated in recent expe

211 e primarily due to 5HT-induced modulation of membrane currents that indirectly affect junctional coup

212 GABA elicited desensitizing membrane currents that recovered after a few minutes' wa

213 nated the high affinity site and resulted in membrane currents that were only partially inhibited at

214 rge inward (toward the cytosolic side of the membrane) current that is activated in a time-dependent

215 hough ischaemia evokes a glutamate-triggered membrane current, this is generated by a rise of extrace

216 uently recovered accurate estimates of patch membrane current through deconvolution.

217 Membrane current through voltage-sensitive calcium ion c

218 deled as spatially and temporally nonuniform membrane currents through mechanosensitive channels, the

219 tes results in light-dependent activation of membrane currents through the Galpha(q)/Galpha(11) G pro

220 Exposure to NH4Cl increased the membrane currents to a similar extent in uninjected oocy

221 ing recorded from, and to attribute measured membrane currents to expressed ion channels or receptors

222 sets the maximal conductances for its active membrane currents to values that produce a predefined ta

223 irect activator of TRPC6 both augmented cell-membrane currents; TRPC6 deficiency abrogated these incr

224 Membrane currents under voltage clamp were determined in

225 Different blends of membrane currents underlie distinct functions of neurons

226 ll caused a slow TBOA-sensitive decay in the membrane current upon prolonged application, which provi

227 rat dorsal root ganglia neurons, we measured membrane currents, using the patch-clamp whole-cell tech

228 ltraviolet light produced rapidly activating membrane currents via activation of endogenous G protein

229 A membrane current was detected with the pharmacology, vol

230 The increased membrane current was inhibited by either 2 mM calcium, o

231 s and RyRs to SK and BK channels, whole cell membrane current was measured in isolated myocytes bathe

232 In control, total membrane current was net outward (hyperpolarizing) near

233 With K+ currents blocked, total membrane current was outward during the late plateau of

234 Membrane current was recorded from intact, isolated rods

235 When membrane current was recorded simultaneously, the calciu

236 d with double-barrelled micro-electrodes and membrane current was recorded under voltage clamp in the

237 The voltage dependence of membrane current was similar in all neurons examined, su

238 Using a Hodgkin-Huxley-style model of membrane currents, we show that differences in the influ

239 The DHPG effects on bursting and membrane current were attenuated by flufenamic acid and

240 [Ca(2+)](i) and membrane current were measured in human submandibular gl

241 The EC50 values for SP and [beta-Ala8]NKA membrane currents were 78 and 33 nM, respectively.

242 Citrate-induced membrane currents were also sensitive to pH, consistent

243 Membrane currents were analyzed using whole-cell, patch-

244 sms of action for NGF and ceramide, isolated membrane currents were examined.

245 Membrane currents were measured using the perforated pat

246 Membrane currents were measured with the use of the whol

247 were assessed using hydroethidium (HEt); and membrane currents were measured with the whole-cell conf

248 Membrane currents were recorded using a two-electrode vo

249 and indo-1 while action potentials (APs) or membrane currents were recorded using patch-type microel

250 Membrane currents were recorded using whole cell patch c

251 Membrane currents were recorded while manipulating the e

252 ld, high-speed, digital imaging system while membrane currents were simultaneously recorded using who

253 Membrane currents were strongly and reversibly inhibited

254 Membrane currents were studied in single human blood eos

255 Membrane currents were subsequently recorded with whole-

256 is detected by measuring the change in trans-membrane current when the analyte is added to the nanotu

257 ostone (an EP3 agonist) had little effect on membrane current, whereas butaprost methyl ester (an EP2

258 d propagation, suggesting that modulation of membrane currents which affect propagation in the apical

259 This protection also alters a surface membrane current, which may be important in myocardial p

260 The reuptake process generates membrane currents, which can be activated by synapticall

261 s from zebrafish rods and cones by recording membrane current with a suction electrode.

262 onstrates the compatibility of the resulting membrane current with the solubility diffusion model.

263 tivation of Cl--dependent outward-rectifying membrane currents with an anion permeability sequence of

264 Whole cell membrane currents with distinctive inward and outward re

265 orm functional homomeric channels, displayed membrane currents with properties distinct from those ex

266 Correlation of membrane currents with radiolabeled myo-inositol flux re