ライフサイエンスコーパス: memory impairment

1 s high and low estradiol mice, and predicted memory impairment.

2 d non-memory cognitive domains contribute to memory impairment.

3 hanism is responsible for the age-associated memory impairment.

4 episodic-like accuracy and induced a general memory impairment.

5 bodies with higher binding strengths induced memory impairment.

6 itiator of synaptic plasticity and long-term memory impairment.

7 the limbic system network and an associated memory impairment.

8 as hemiplegia, mood disorders, cognitive and memory impairment.

9 (CB1) receptors abolished the stress-induced memory impairment.

10 etion contributes to learning deficiency and memory impairment.

11 herapeutic interventions for obesity-induced memory impairment.

12 IRT1 could be responsible for obesity-linked memory impairment.

13 vivo, resulting in hyperactivity and spatial memory impairment.

14 including DAI and clinical sequelae such as memory impairment.

15 cipal pathogenic mediator of obesity-induced memory impairment.

16 of the two peptides combined lead to LTP and memory impairment.

17 R2A predicts severity of age-related working memory impairment.

18 ll recent events occurred after the onset of memory impairment.

19 encoding of spatial information and spatial memory impairment.

20 cated in the pathogenesis of obesity-induced memory impairment.

21 or (GluA23Y) before rapamycin prevented this memory impairment.

22 normalities, including decreased anxiety and memory impairment.

23 this plasticity is altered in aged rats with memory impairment.

24 understood, particularly in mouse models of memory impairment.

25 active in specific brain regions involved in memory impairment.

26 n increase with aging, which correlates with memory impairment.

27 early indicator of Alzheimer's disease (AD) memory impairment.

28 l damage has been thought to result in broad memory impairment.

29 d-beta (Abeta) deposition and improvement of memory impairment.

30 cal pattern of progression and an associated memory impairment.

31 vous system manifestations including spatial memory impairment.

32 ble tau species cause cognitive deficits and memory impairment.

33 Patients showed selective memory impairment.

34 llowing VGKCC-Ab-LE and its role in residual memory impairment.

35 ge number of neurological deficits including memory impairment.

36 leads to hippocampal atrophy and persistent memory impairment.

37 VGKCC-Ab-LE results in persistent isolated memory impairment.

38 n (LTP) deficit that was not associated with memory impairment.

39 participates in the development of long-term memory impairment.

40 ampal gamma power predicted the magnitude of memory impairment.

41 tion, as well as contextual fear and spatial memory impairments.

42 mpus and preventing SE-induced cognitive and memory impairments.

43 may have therapeutic potential for reversing memory impairments.

44 fications in PL-mPFC and causes long-lasting memory impairments.

45 and evaluation of strategies for alleviating memory impairments.

46 aling, consistent with observed learning and memory impairments.

47 y contributes to apoE4-mediated learning and memory impairments.

48 the dlPFC can prevent stress-induced working memory impairments.

49 eatments to improve TBI-induced learning and memory impairments.

50 tered during this consolidation period cause memory impairments.

51 ork may underlie the majority of age-related memory impairments.

52 for stress-associated molecular changes and memory impairments.

53 ists to treat schizophrenia-spectrum working memory impairments.

54 seline memory performance or post-ECT verbal memory impairments.

55 tivity underpinnings of ECT-induced episodic memory impairments.

56 DG) of the hippocampus, alongside associated memory impairments.

57 , trauma exposure results in fear-associated memory impairments.

58 cells, and gliosis, culminating in motor and memory impairments.

59 a2 is selectively impaired in aged rats with memory impairments.

60 d the role of Nr4a1 and Nr4a2 in age-related memory impairments.

61 ly member, Nr4a1, can ameliorate age-related memory impairments.

62 ents were apathy (23%), disinhibition (18%), memory impairments (12%), decreased fluency (8%) and imp

63 in the cortex and hippocampus, and improved memory impairment 2 weeks after trauma.

64 with drug treatment might be useful to treat memory impairment, a kind of cognitive problem in Parkin

65 men with low testosterone and age-associated memory impairment (AAMI).

66 eimer's disease and that this contributes to memory impairment, abnormal APP processing and tau hyper

67 of post-traumatic amnesia and evidence that memory impairment acutely after traumatic brain injury r

68 itive deficits (e.g., executive function and memory impairments), affective information processing pa

69 ls can expect to show clinically significant memory impairment after 3 years, whereas Abeta(+)varepsi

70 findings for a patient (A.B.), who developed memory impairment after a cardiac arrest at age 39.

71 baric oxygen treatment may alleviate delayed memory impairment after acute carbon monoxide poisoning

72 l systems-level mechanism to explain spatial memory impairment after moderate PAE.

73 , but the precise role of PERK activation in memory impairment after TBI has not been well elucidated

74 using GSK2656157 would be beneficial against memory impairment after TBI.

75 ia, not seizures per se, are associated with memory impairment after temporal lobe seizures.

76 dicate a causal role of the dlPFC in working memory impairments after acute stress and point to anoda

77 of corticosterone and CRH underlie enduring memory impairments after concurrent acute stresses, whic

78 one and CRH at hippocampal synapses underlie memory impairments after concurrent and perhaps also sin

79 eliorate the gliovascular damage and working memory impairments after hypoperfusion possibly via endo

80 trate of working memory, may prevent working memory impairments after stress.

81 eurological patients who reported subjective memory impairment (age range: 50-83 years).

82 GNIFICANCE STATEMENT Aging is accompanied by memory impairments, although there is a great deal of va

83 rovided evidence of increased propensity for memory impairment among PPI reports when compared to his

84 Her medical history included memory impairment and a left posterior cerebral artery t

85 logical estradiol experienced stress-induced memory impairment and a loss of underlying synapses.

86 These effects were accompanied by memory impairment and a reduction of surface NMDARs, as

87 tions between cognitive impairment including memory impairment and alpha-synuclein pathology, 148 con

88 we evaluated mouse models of age-associated memory impairment and amyloid deposition to study transc

89 ermore, injection of a PKR inhibitor rescued memory impairment and attenuated ATF4 mRNA increased exp

90 Prosopagnosia, episodic memory impairment and behavioural changes such as disinh

91 of low-intensity pulsed (LIP) ultrasound on memory impairment and central nervous system injury in a

92 ing the function of mAChRs are used to treat memory impairment and decline.

93 SCI caused spatial and retention memory impairment and depressive-like behavior, as evide

94 egions consistent with their greater working memory impairment and development of behavioral symptoms

95 s compared with placebo, in patients who had memory impairment and elevated brain amyloid levels but

96 f synaptic connectivity is linked to working memory impairment and is specific to repeated exposure t

97 the cortex and hippocampus, concomitant with memory impairment and neurodegeneration, in adult mice.

98 eptor Ca(2+) release, reverses aging-induced memory impairment and neuronal Ca(2+) dysregulation.

99 attenuation of protein synthesis, leading to memory impairment and neuronal loss.

100 mice partially rescued beta-amyloid-mediated memory impairment and neuropathology.

101 centration was associated with the immediate memory impairment and psychopathology of SCH.

102 role of CB1 cannabinoid receptors (CB1Rs) in memory impairment and spine density changes induced by n

103 n chronic seizure development and associated memory impairment and suggest that targeting aberrant hi

104 Alzheimer's disease (AD) suffer from spatial memory impairment and wandering behavior, but the brain

105 LAE Type 2; n = 13) did not show declarative memory impairment and were indistinguishable from patien

106 tion as a therapeutic strategy to ameliorate memory impairments and brain structural defects in the D

107 uman apoE4 causes age-dependent learning and memory impairments and degeneration of GABAergic interne

108 both male and female) displayed mild spatial memory impairments and disrupted cingulate network conne

109 eurin dyshomeostasis underlies age-dependent memory impairments and further imply that chronic Nebula

110 Memory impairments and hippocampal demyelination are com

111 role for hypoperfusion/hypoxia in postictal memory impairments and identify that many aspects of hip

112 atures were headache, a cerebellar syndrome, memory impairment, and altered consciousness.

113 The psychotic-like features, memory impairment, and changes in levels of D1R, D2R, an

114 A positive family history, memory impairment, and clinical abnormalities at present

115 es a new murine model of WNV-induced spatial memory impairment, and identifies a potential mechanism

116 Seizures, memory impairment, and increased protein content in cere

117 hyperactivity, some defects in motor skills, memory impairment, and reduced anxiety, but in the absen

118 namely prepulse inhibition decrease, working memory impairment, and social memory deficits, as well a

119 5 expression critically drives Abeta-induced memory impairment, and strategies aimed at reducing Ephe

120 ently improved, but one patient had residual memory impairment, and the other patient had a residual

121 re largely responsible for the synapticloss, memory impairments, and neurotoxicity that underlie Alzh

122 prevent Abeta oligomers-induced synaptic and memory impairments, and offered a strong support for the

123 rrents, and rescued social deficits, working memory impairments, and seizure behavior latency in R59X

124 ypes, including motor coordination, episodic memory impairments, and synaptic plasticity deficits.

125 e, disinhibition or stereotypy; six had pure memory impairment; and 12 had both types of impairment.

126 Memory impairments are characterized by accelerated deca

127 In conclusion, working memory impairments are common and significantly impact t

128 Learning and memory impairments are common in traumatic brain injury

129 of age-related sleep disruption, focusing on memory impairment as an exemplar.

130 aspects of AD pathophysiology which includes memory impairments as well as synaptic integrity.

131 imes per week, 4 weeks) rescued learning and memory impairments, as measured by three different behav

132 at it is possible to detect the signature of memory impairment associated with Parkinson's disease in

133 interleukin-1beta (IL-1beta) plays a role in memory impairment associated with various neurological d

134 for treatment of both seizures and comorbid memory impairments associated with epilepsy.

135 in designing new therapies to treat working memory impairments by enhancing the function of NR2A-con

136 Here, we test DBS for its ability to improve memory impairments by stimulating the entorhinal cortex

137 n vivo, leading to a selective abrogation of memory impairments caused by exposure to THC.

138 However, ECT frequently results in episodic memory impairments, causing many patients to discontinue

139 s and predicts both entorhinal pathology and memory impairment, challenging the widely held belief th

140 this study, we evaluated whether the working-memory impairment characteristic of animal models of chr

141 s a cellular mechanism for the attention and memory impairments comorbid with chronic pain.

142 th LOC were more likely to report subjective memory impairment compared to those without TBI even aft

143 cture and function contribute to age-related memory impairment, complementing findings in the rodent

144 's disease whilst tests sensitive to working memory impairment declined earlier in typical Alzheimer'

145 Pups of FASD mothers displayed short-term memory impairment, decreased hippocampal size and decrea

146 l features of schizophrenia, such as working memory impairments, depend on distributed neural circuit

147 (NMDAR) encephalitis suffer from persistent memory impairment despite unremarkable routine clinical

148 stems, patients with the same combination of memory impairment developed more neuronal inclusions in

149 Memory impairment during nicotine withdrawal was blocked

150 odafinil), medications used in patients with memory impairment (eg, donepezil, memantine, and ginkgo

151 Auditory working memory impairments feature prominently in schizophrenia.

152 ative brain circuits permits compensation of memory impairments following damage to brain regions spe

153 is consistent with navigational and episodic memory impairments following damage to this region in hu

154 hese processes might contribute to amplified memory impairments following short, multimodal stress.

155 nal disorder in neuronal activity and social memory impairments for partner discrimination observed i

156 frontal-subcortical dysfunction (n = 12) and memory impairment + frontal-subcortical dysfunction (n =

157 y impairment (pure memory impairment: n = 6; memory impairment + frontal-subcortical dysfunction: n =

158 of people with isolated substantial relative memory impairment had >=1 APOE epsilon4 allele than any

159 e disease was first described, their role in memory impairment has been poorly understood.

160 Age-related memory impairments have been associated with structural

161 Similar working memory impairments have been observed in healthy individ

162 nd reverted the neurodegeneration-associated memory impairment in a passive avoidance paradigm.

163 ht to cause severe clinical symptoms such as memory impairment in AD patients.

164 s aimed to resolve the cognitive decline and memory impairment in AD using DBS of hippocampal afferen

165 ultimately leading to neurodegeneration and memory impairment in AD.

166 of patients and are thought to contribute to memory impairment in AD.

167 asks may be useful in detecting the earliest memory impairment in AD.

168 loid fibrils, cause neuronal dysfunction and memory impairment in AD.

169 on, as circuit mechanisms underlying spatial memory impairment in AD.

170 gent capable of opposing synapse failure and memory impairment in AD.

171 associates with naturally occurring working memory impairment in aged rats.

172 ng FKBP1b reversed calcium dysregulation and memory impairment in aging rats, allowing them to perfor

173 s a novel target for therapeutics to improve memory impairment in Alzheimer disease patients.Molecula

174 (42)) induce synaptic dysfunction leading to memory impairment in Alzheimer's disease (AD).

175 Memory impairment in Alzheimer's disease is a manifestat

176 We confirmed that memantine antagonizes memory impairment in Alzheimer's model APP23 mice.

177 led to the acceleration of tau pathology and memory impairment in an hTau mouse model of tauopathy.

178 companied by significant hippocampus-related memory impairment in both models.

179 physiologic determinant of cytokine-induced memory impairment in brain.

180 n, neuroinflammation, synaptic pathology and memory impairment in control mice, but not in mice lacki

181 e anatomic and neuropathologic correlates of memory impairment in dementia with Lewy bodies (DLB) rem

182 tionally relevant than CA2 in the context of memory impairment in DLB.

183 dynamics are candidate neural mechanisms for memory impairment in DS.

184 t that inhibition of PKR is a way to restore memory impairment in early stages of sporadic AD.

185 is a way to restore ATF4 overexpression and memory impairment in early stages of sporadic AD.

186 which suggests a target for the treatment of memory impairment in epilepsy.

187 he stress-induced glutamatergic deficits and memory impairment in females, and the level of aromatase

188 t functions in humans, on the time course of memory impairment in human cases with early hippocampal

189 evented hippocampal dendritic spine loss and memory impairment in mice that received an intracerebrov

190 reduced hippocampal dendritic spine loss and memory impairment in mice that received intracerebrovent

191 significantly increased risk for subjective memory impairment in models adjusted for demographics an

192 artate 314 mediates synaptic dysfunction and memory impairment in mouse and cellular models of neurod

193 rious aspects of the molecular pathology and memory impairment in mouse models of AD.

194 ocampus is associated with the occurrence of memory impairment in multiple system atrophy.

195 peutic strategy for treatment of age-related memory impairment in neurodegenerative diseases.

196 mory deficits in rats and attenuated working memory impairment in NMDA Nr1(neo-/-) mice.

197 ethyl metabolism, embryonic growth delay and memory impairment in offspring.

198 pid eye movement (NREM) sleep disruption and memory impairment in older adults.

199 de 2 hypertension, dermatitis acneiform, and memory impairment in patient 1, and grade 2 hyperbilirub

200 k and the medial temporal lobe contribute to memory impairment in PD.

201 dysfunction in these regions contributes to memory impairment in PD.

202 microbiota in the ability of BDPP to prevent memory impairment in response to SD.

203 we summarize the neuronal basis for working memory impairment in schizophrenia, including dysfunctio

204 relevant in an effective therapy for working memory impairment in schizophrenia.

205 n structural and functional deterioration to memory impairment in the Alzheimer's disease (AD) contin

206 he fornix showed a stronger association with memory impairment in the early aMCI stage; such WM-memor

207 ylation in human neuronal cells and reverses memory impairment in transgenic tau nematodes and mice.

208 50 (BAY) affected Abeta-induced learning and memory impairment in two classic rodent models.

209 se of the central nervous system, leading to memory impairment in up to 65% of patients.

210 glia contribute to neuronal loss, as well as memory impairments in 5xfAD mice, but do not mediate or

211 can prevent developmental delay and AD-like memory impairments in a DS mouse model.

212 medial temporal lobe (MTL) underlie episodic-memory impairments in AD dementia.

213 upregulation may contribute to age-dependent memory impairments in AD in DS.

214 ay in pups and AD-like hippocampus-dependent memory impairments in adult life in Ts65Dn mice.

215 elucidating the neural mechanisms underlying memory impairments in aging and dementia.

216 NMDAR loss in PFC may account for working memory impairments in aging and psychiatric disease.

217 mory retrieval and offer new perspectives on memory impairments in dopamine-related disorders and the

218 impact memory is critical for understanding memory impairments in epilepsy patients.

219 olves multiple events, and notably, episodic memory impairments in human diseases are not limited to

220 o methamphetamine (meth) can produce lasting memory impairments in humans and rodents.

221 s occurring simultaneously result in spatial memory impairments in males, but effects on females are

222 ed by clinical reports of long-term episodic memory impairments in psychiatric conditions with dissoc

223 roscience revealed disproportionate episodic memory impairments in schizophrenia (Sz) under high cogn

224 ese effects were shown to be correlated with memory impairments in the working memory task.

225 us system where it modulates amyloidosis and memory impairments in transgenic mouse models of Alzheim

226 rexidine (DAR-0100A) could attenuate working memory impairments in unmedicated patients with schizoty

227 ion in rats was sufficient to drive age-like memory impairments in young animals and to uncover a hip

228 hibitor that also inhibits mTOR, reduced the memory impairment induced by Abeta.

229 lpha and anti-NL1 antibodies further blocked memory impairment induced by AbetaOs in mice.

230 mice also exhibited a resistance of working memory impairment induced by injection of NMDAR antagoni

231 l effects of this enriched diet on cognitive memory impairment induced by social instability stress,

232 JH-deficit-induced memory impairment involves rapid decay rather than failu

233 This threat memory impairment is also reflected in increased behavio

234 Associative memory impairment is an early clinical feature of dement

235 ith age, but the cause of this age-dependent memory impairment is not well understood.

236 Memory impairment is often associated with disrupted reg

237 Memory impairment is the cardinal early feature of Alzhe

238 In Alzheimer's disease (AD), memory impairment is the most prominent feature that aff

239 h damage to the human fornix also results in memory impairment, it is not known whether there is a pr

240 We examined whether visual short-term memory impairments, long associated with patients with P

241 ing on tangents, suggesting that anterograde memory impairment may have interfered with narrative con

242 Abeta-overproducing mice showed significant memory impairment, memories in GluA3-deficient congenics

243 haviors, and some social impairments but not memory impairments, motor deficits, or overgrooming.

244 ition, patients with memory impairment (pure memory impairment: n = 6; memory impairment + frontal-su

245 In addition, we aimed at reversing the memory impairment observed in a mouse model of sporadic

246 the bEKO mice did not have the learning and memory impairment observed in ApoE KO mice.

247 Memory impairment occurred despite preserved hippocampal

248 ed the pro-depressive effects and short-term memory impairment of MS.

249 The memory impairment of neurological and psychiatric patien

250 ce with the PKRi before learning rescues the memory impairment of the ApoE4 AD model mice.

251 veal a key mechanism underlying learning and memory impairments of PNN-associated neurodevelopmental

252 whether MTL tau pathology also accounts for memory impairments often seen in elderly people and how

253 he strength of this beta echo was related to memory impairment on a between-subjects level.

254 angle pathology, focal neuroinflammation and memory impairment on an accelerated time scale.

255 epilepsy at just 5 weeks of age, long before memory impairments or beta-amyloid deposition.

256 cifics, a change that did not involve global memory impairments or increased anxiety.

257 participants (P < .001) and athletes without memory impairment (P < .001).

258 e novel arm of the Y maze because of spatial memory impairments (P < .05).

259 atients with normal cognition, patients with memory impairment (pure memory impairment: n = 6; memory

260 changes after ECT can track patients' verbal memory impairments (r = 0.613, p = 0.008).

261 n the level of PLXNA4 is sufficient to cause memory impairments, raising the possibility that memory

262 ance deficit more likely indicates a genuine memory impairment rather than a retrieval failure.

263 zygous BDNF Val66Met females exhibit spatial memory impairment, regardless of acute stress.

264 but mechanisms underlying this age-dependent memory impairment remain poorly understood.

265 hich includes Abeta plaques, tau tangles and memory impairments remain unknown.

266 receptors (D2Rs), on cognitive deficits and memory impairments remains questionable.

267 er it also can ameliorate neural circuit and memory impairments remains unclear.

268 ic interneurons, which prevents learning and memory impairments, rescued SWR-associated slow gamma ac

269 The spatial working memory impairment shown here has the potential to harm b

270 on as an underlying mechanism of age-related memory impairment.SIGNIFICANCE STATEMENT Alterations in

271 get for the treatment of disorders involving memory impairments.SIGNIFICANCE STATEMENT The dentate gy

272 ew insight in the role of CA3 in age-related memory impairments, suggesting that the rigid representa

273 evere AD pathology and significantly greater memory impairments than untreated animals.

274 Mice infected with C. albicans display mild memory impairment that resolves with fungal clearance.

275 GI produced spatial memory impairment that was ameliorated by DBS, with no d

276 accompanied by cognitive problems, including memory impairments that contribute to poor quality of li

277 tation, urolithin A, and actinonin) reverses memory impairment through PINK-1 (PTEN-induced kinase-1)

278 men with low testosterone and age-associated memory impairment, treatment with testosterone for 1 yea

279 retrograde facilitation and alcohol induced memory impairment using two independent tasks.

280 ciations between abnormal brain measures and memory impairment varied throughout disease continuum.

281 Memory impairment was associated with the loss of adult-

282 ty analyses revealed that risk of subjective memory impairment was increased only among respondents w

283 ive depression, however, risk for subjective memory impairment was no longer significant (RR [95% CI]

284 This stress-induced working memory impairment was prevented by anodal, but not sham

285 Moreover, memory impairment was prevented by the selective mammali

286 Furthermore, the risk of subjective memory impairment was significantly greater among those

287 Remarkably, an improvement of the memory impairments was also observed.

288 relationship between brain abnormalities and memory impairment, we aimed to examine the stage-depende

289 nderstand the underlying mechanisms of these memory impairments, we examined hippocampal long-term po

290 entify individual differences in age-related memory impairments, we first identified Nr4a2 as a key g

291 heral overexpression of FNDC5/irisin rescues memory impairment, whereas blockade of either peripheral

292 ying demonstrated the typical stress-related memory impairment, whereas those who learned by retrieva

293 s are increasingly recognized as causing the memory impairments which define Alzheimer's disease (AD)

294 ns, and either altered mental status or mild memory impairment), which are considered more reliable t

295 be epilepsy present with a broad spectrum of memory impairment, which can be assessed during clinical

296 ally diagnosed as unknown or with subjective memory impairment who were later rediagnosed with aMCI/A

297 s with aMCI/AD from patients with subjective memory impairment with a sensitivity of 0.79 and specifi

298 buprofen, and found that ibuprofen prevented memory impairment without producing any measurable chang

299 pathological concomitant of obesity-induced memory impairment, yet a deeper understanding of the bas

300 tion associated with cancer and learning and memory impairment, yet our understanding of this epigene