ライフサイエンスコーパス: mental illness

1 e risk for the development of stress-induced mental illness.

2 lopment has been hypothesized to account for mental illness.

3 targeted specifically at people with severe mental illness.

4 natural-cause mortality in those with severe mental illness.

5 mproved outcomes for patients suffering from mental illness.

6 ct dysfunctional thinking present in serious mental illness.

7 development, determining risk for subsequent mental illness.

8 s about mental illness or about persons with mental illness.

9 nd its disruption is a significant factor in mental illness.

10 YOD bed-days before age 40 years were due to mental illness.

11 of decision making in preclinical models of mental illness.

12 The main outcome was prevalence of maternal mental illness.

13 s relative to vignettes portraying untreated mental illness.

14 nt and increase the risk for and severity of mental illness.

15 e prevalence of children exposed to maternal mental illness.

16 ) individuals had an antecedent diagnosis of mental illness.

17 key feature of this often devastating severe mental illness.

18 h (Ontario, Canada, 2005-2015) and no recent mental illness.

19 ly vulnerable to dysregulation implicated in mental illness.

20 controls, particularly related to trauma and mental illness.

21 tilized to dissect the genetic influences on mental illness.

22 about mental illness and about persons with mental illness.

23 promising instrument for predicting risk for mental illness.

24 l effects of infection and associations with mental illness.

25 lth-care needs of people living with HIV and mental illness.

26 compared to white British groups with severe mental illness.

27 ding influences shared by smoking and severe mental illness.

28 then compared with those of patients without mental illness.

29 entification of individuals at high risk for mental illness.

30 impairments in this chronic and debilitating mental illness.

31 ism linking early life risk factors to adult mental illness.

32 597, which has been strongly linked to major mental illness.

33 the entire cortex, and they are abnormal in mental illness.

34 trong social support increases resilience to mental illness.

35 hed as a robust genetic risk factor in major mental illness.

36 utes to the emergence of individual risk for mental illness.

37 of general liability as individual risk for mental illness.

38 e, training, and research; and beliefs about mental illness.

39 health of people with or at risk of serious mental illness.

40 1.43%) individuals had a diagnosis of severe mental illness.

41 candidate protein in the pathology of major mental illness.

42 rocess underlying the development of chronic mental illness.

43 Nearly 3% of patients had preexisting severe mental illness.

44 for the overrepresented group of people with mental illness.

45 ive functions that are commonly disrupted in mental illness.

46 y factors that may precede maladjustment and mental illness.

47 cortex provides insight into the etiology of mental illness.

48 largest environmental risk factor for adult mental illness.

49 e management of contraception for women with mental illness.

50 n they are treated for an initial episode of mental illness.

51 10 [1.27-3.49]), compared with no history of mental illness.

52 rapeutic for treatment-resistant symptoms of mental illness.

53 replicated serological observations in major mental illness.

54 h (Ontario, Canada, 2005-2015) and no recent mental illness.

55 erstanding of both normal brain function and mental illness.

56 rtant role in pathologies such as stroke and mental illness.

57 1-6.4), 2927 (5.0%) of whom had a history of mental illness.

58 uals from multiple Finnish cohorts for major mental illnesses.

59 that have been associated by GWAS with major mental illnesses.

60 e roles of these changes in vulnerability to mental illnesses.

61 and anxiety were the most prevalent maternal mental illnesses.

62 specifically designed for people with severe mental illnesses.

63 chosocial adversity induces vulnerability to mental illnesses.

64 covery in brain disorders, including serious mental illnesses.

65 nce in outpatients with co-occurring serious mental illnesses.

66 ls, leading to manifestation as physical and mental illnesses.

67 ated in the pathophysiology of these complex mental illnesses.

68 ted with cognitive and emotional deficits in mental illnesses.

69 al signatures of core dysfunctions underling mental illnesses.

70 of this protein in a variety of devastating mental illnesses.

71 of new strategies to treat stress-associated mental illnesses.

72 logical mediators in both diabetes and major mental illnesses.

73 is also observed in some patients with major mental illnesses.

74 ntrol is negatively impacted in a variety of mental illnesses.

75 e a risk for the later development of severe mental illnesses.

76 ve in poverty disproportionately affected by mental illness?

77 reast cancer (k=35; 296 699 individuals with mental illness, 1 023 288 in the general population), ce

78 tion within the first year after surgery (no mental illness: 1.88 per 100,000 individuals; anxiety/de

79 kely than those without to develop perinatal mental illness (18.1% vs. 16.0%; adjusted relative risk

80 kely than those without to develop perinatal mental illness (18.1% vs. 16.0%; adjusted relative risk:

81 ple and is epidemiologically linked to major mental illnesses(2) and cognitive impairment(3).

82 tion), and prostate cancer (k=6; 52 803 with mental illness, 2 038 916 in general population).

83 tion), colorectal cancer (k=12; 153 283 with mental illness, 2 228 966 in general population), lung a

84 ession: 51.3 per 100,000 individuals; severe mental illness: 238.9 per 100,000 individuals).

85 lation), cervical cancer (k=29; 295 688 with mental illness, 3 540 408 in general population), colore

86 the first 3 mo after their initial claim for mental illness, 44.85% of children who receive drug trea

87 f developing depression, anxiety, or serious mental illness (a composite mental ill health outcome) o

88 s to recognise and classify posts related to mental illness according to 11 disorder themes.

89 tios were elevated in the cohort with severe mental illness across all neighbourhood-level characteri

90 Postoperative radiation and mental illness adversely impacted satisfaction with brea

91 e mental illness compared with those without mental illness after adjusting for age, income, race, et

92 milar in different ethnic groups with severe mental illness, although the south Asian group had a red

93 utilisation data (N = 727); (2) detection of mental illness among participants presenting in primary

94 Data on behavioral correlates of mental illness among young people who inject drugs (PWID

95 rams (SSPs) could benefit from screening for mental illness among young PWID and strong linkage to he

96 depressive disorder (MDD) is a debilitating mental illness and a major cause of lost productivity wo

97 endorsed stigmatizing personal beliefs about mental illness and about persons with mental illness, ir

98 e personal beliefs and perceived norms about mental illness and about persons with mental illness.

99 nxiety disorders are the most common form of mental illness and are more likely to emerge during chil

100 Early life stress predisposes to mental illness and behavioral dysfunction in adulthood,

101 ve quality of care for patients with serious mental illness and cardiovascular risk factors.

102 care for people with chronic (or recurring) mental illness and comorbid physical health conditions,

103 her prevalence of BBVs in people with severe mental illness and identify interventions preventing inf

104 works and canonical pathways associated with mental illness and molecular signaling processes (e.g.,

105 A total of 447 patients with a serious mental illness and one or more cardiometabolic risk fact

106 dicated substantially higher rates of severe mental illness and substance use disorders among prisone

107 ons reporting prevalence estimates of severe mental illness and substance use disorders for 14 527 pr

108 vides estimates for the prevalence of severe mental illness and substance use disorders in incarcerat

109 dren aged 0-16 years are exposed to maternal mental illness and the prevalence of diagnosed and treat

110 Across all types of mental illness and treatment scenarios, relative to the

111 or dysregulation more broadly in other major mental illnesses and behavioral disorders.

112 demonstrated an association between various mental illnesses and cardio-cerebrovascular disease (CVD

113 he strength of association between different mental illnesses and CVD risk.

114 e bi-directional relationships between major mental illnesses and diabetes suggest that there may be

115 ar brain aging is a common feature of severe mental illnesses and neurodegeneration.

116 eir validity as predictors of risk for major mental illnesses and neurodegenerative disorders.

117 mplications for the pathophysiology of major mental illnesses and the development of novel therapeuti

118 1.28 for PTSD and 1.28, 1.16-1.41 for severe mental illness) and the number of social integration str

119 4 717 839 individuals (501 559 patients with mental illness, and 4 216 280 controls), of whom 69.85%

120 Similarly, negative economic shocks cause mental illness, and antipoverty programs such as cash tr

121 patients with breast cancer with preexisting mental illness, and elderly women are of special interes

122 n suicide risk, even in the context of other mental illness, and implicate the time frame shortly aft

123 psychosis, which are markers of severity of mental illness, and older age, which is a marker of chro

124 , socioeconomic factors, parental history of mental illness, and parental age.

125 risks for the next generation (eg, violence, mental illness, and substance use).

126 conditions, self-care in persons with severe mental illness, and the influence of others (care partne

127 ction, is a common genetic locus of risk for mental illnesses, and remains one of the most prominentl

128 ny type of cancer screening in patients with mental illness; and studies that reported prevalence of

129 Since people with mental illness are more likely to die from cancer, we as

130 most risk factors for later vulnerability to mental illness are readily measured using existing, clin

131 associated with familial risk for developing mental illnesses are largely unknown.

132 We defined severe mental illness as a clinical diagnosis of schizophrenia,

133 teins in the brains of patients with chronic mental illness as a result of disruptions in proteostasi

134 Understanding of mental illness as a treatable medical condition may infl

135 inical phenotype in some patients with major mental illness as well as to improved nosology and ident

136 Criteria (RDoC) framework for understanding mental illnesses as brain circuit disorders that extend

137 was to define the prevalence of preexisting mental illness, as well as characterize the impact of a

138 We examined the risk of any perinatal mental illness associated with pre-pregnancy diabetes an

139 We examined the risk of any perinatal mental illness associated with prepregnancy diabetes and

140 the most likely functional variant for major mental illness at the PDE4D locus in the Finnish populat

141 l can help identify potential sufferers with mental illness based on their posts.

142 individuals with a valid diagnosis of severe mental illness between Jan 1, 2007, and Dec 31, 2014, fr

143 le in modifying mortality outcomes in severe mental illness, but has received little attention to dat

144 xplains why reductionism is not possible for mental illness, but the same argument applies for the so

145 r disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its genetic bas

146 T. gondii) antibodies in patients with major mental illnesses, but the underlying mechanism was uncle

147 ative risk of children experiencing maternal mental illness by age 16 years.

148 enia-1 (DISC1) protein is a driver for major mental illness by influencing neurodevelopmental process

149 sence and progression of depression or other mental illnesses by jointly representing and modeling th

150 anistic hypotheses related to the biology of mental illness, by combining well-characterized neurobio

151 Maternal mental illness can have a devastating effect during the

152 for posttraumatic stress disorder (PTSD), a mental illness characterized by the recurring avoidance

153 Major depressive disorder (MDD) is a serious mental illness, characterized by high morbidity, which h

154 ortality hazard between patients with severe mental illness compared with those without mental illnes

155 tality in ethnic minority groups with severe mental illness compared with white British people with s

156 Proactive management of mental illness, contraception, and pregnancy improves a

157 Individuals were followed up until onset of mental illness, death, emigration, or the end of the stu

158 usal relationship between poverty and common mental illnesses-depression and anxiety-and the underlyi

159 om the CRPD to define the following maternal mental illnesses: depression, anxiety, non-affective psy

160 as characterize the impact of a preexisting mental illness diagnosis on postoperative outcomes.

161 10 Medicare beneficiaries had a preexisting mental illness diagnosis, which was strongly associated

162 whereas a smaller subset (8.2%) had a severe mental illness diagnosis.

163 rn Uganda, portrayals of effectively treated mental illness did not appear to reduce endorsement of s

164 homolog, NVL2 has been linked to cancer and mental illness disorders, highlighting the need to under

165 C1), a well-accepted genetic risk factor for mental illness, display abnormal behaviours in response

166 greater emotional well-being, lower risk of mental illness, eating disorders, overweight or obesity

167 eased risk of CVD outcomes, with more severe mental illnesses (eg, primary psychotic disorders) havin

168 nical subgroup, despite the heterogeneity of mental illnesses examined.

169 the principal mediator in the development of mental illness following exposure to trauma.

170 mate excess mortality for people with severe mental illness for five ethnic groups (white British, bl

171 g and investigate the importance of parental mental illness for such an association.

172 Risk for subsequent mental illness for those who lived with the lowest level

173 r more at the time of diagnosis for a severe mental illness from Jan 1, 2007, to Dec 31, 2014.

174 I: 1.07-1.30) and cognitive domains of major mental illnesses (g-score p = 0.044, beta = -0.033).

175 Patients with preoperative mental illness had a higher chance of surgical complicat

176 Additionally, individuals with mental illness had a higher prevalence of suicidal ideat

177 ty areas, ethnic minority groups with severe mental illness had a lower risk of death (aRR 0.52, 95%

178 al categorical and dimensional approaches to mental illness has become all too apparent.

179 Given that maternal mental illness has negative long-term developmental impl

180 INTERPRETATION: People with severe mental illness have excess mortality relative to the gen

181 is health inequality, but people with severe mental illness have not historically engaged with smokin

182 between particulate matter (PM) exposure and mental illness have not yet been established.

183 ients were considered as having a history of mental illness if they had ever received psychiatric med

184 Furthermore, mental illness impacted physical wellbeing of the chest

185 rrent body of evidence for the prevalence of mental illness in global refugee populations and overcom

186 during pregnancy to increased risk of severe mental illness in offspring (eg, bipolar disorder, schiz

187 between smoking during pregnancy and severe mental illness in offspring, adjusting for measured cova

188 f smoking during pregnancy on risk of severe mental illness in offspring.

189 children and adolescents exposed to maternal mental illness in the UK between 2005 and 2017 using pri

190 cating that the ECSS contributes to risk for mental illness in those exposed to severe stress and tra

191 D, including an unexpectedly large burden of mental illness in young adulthood.

192 h SZ or BP and (2) higher incidence of major mental illnesses in people with diabetes in the same lar

193 health-care practice for people with severe mental illnesses in this region since then.

194 and hepatitis C (HCV) in people with severe mental illness, including the total adult (>/=18 years)

195 e proportion of children exposed to maternal mental illness increased from 22.2% (21.9-22.4) between

196 and highlights potential mechanisms by which mental illness influences long-term outcomes, including

197 tative studies were included if diagnosis of mental illness involved a clinical interview and use of

198 about mental illness and about persons with mental illness, irrespective of mental illness type (adj

199 of adversity emerges as individual risk for mental illness is an important step toward developing st

200 prevalence of diagnosed and treated maternal mental illness is increasing.

201 The number of people affected by mental illness is on the increase and with it the burden

202 Mental illness is one of the most rapidly increasing cau

203 zophrenia (SZ), one of the most debilitating mental illnesses, is thought to arise, in part, from suc

204 diagnoses, but to understand the biology of mental illness it may be more useful to study traits whi

205 One strategy to prevent mental illness may be to target interventions toward chi

206 Conclusion Patients with severe mental illness may need assistance with coordinating med

207 lthough the underlying neurobiology of major mental illness (MMI) remains unknown, emerging evidence

208 te the immense health and economic burden of mental illness, modifiable targets to promote psychologi

209 5% CI, 1.0-12.6]; P = .045), and symptoms of mental illness (mOR, 2.6 [95% CI, 1.2-5.5]; P = .012) we

210 95% CIs for associations between history of mental illness, mortality, and HIV treatment outcomes (r

211 tality rate ratio, MRR 9.8, 95% CI 5-19) and mental illness (MRR 9.1, 95% CI 4-23).

212 al population), ovarian cancer (k=1; 37 with mental illness, none in general population), and prostat

213 lung and gastric cancer (both k=1; 420 with mental illness, none in general population), ovarian can

214 ess mortality among people with a history of mental illness occurred independently of HIV treatment s

215 e of BBVs was elevated in people with severe mental illness, of which 230 (0.24%) had HIV, 518 (0.53%

216 updating across individuals with and without mental illness, online participants, and rats chronicall

217 a transdiagnostic risk factor implicated in mental illness onset, treatment non-response, and suicid

218 % confidence interval (CI) 1.42-1.46, severe mental illness OR 1.71, 95%CI 1.66-1.77] and an extended

219 depression OR 1.45, 95% CI 1.44-1.46, severe mental illness OR 2.34, 95% CI 2.28-2.39).

220 ce endorsement of stigmatizing beliefs about mental illness or about persons with mental illness.

221 udents aged 18 years or older with no severe mental illness or crisis (self-assessed) were randomly a

222 neglect; parental substance abuse; parental mental illness or suicide attempt; violence between pare

223 Portrayals of effectively treated mental illness or treatment followed by subsequent relap

224 ession (OR 1.87, 95% CI 1.85-1.90) or severe mental illness (OR 2.86, 95% CI 2.77-2.94) was also asso

225 was weaker when controlled for past maternal mental illness (OR, 1.52; 95% CI, 1.09-2.12).

226 AFs of causes of ill health were highest for mental illness outcomes: ACEs were attributed to about 3

227 omestic violence (p < 0.05) and a history of mental illness (p < 0.01) were associated with higher sc

228 mental health has reported wide variation in mental illness prevalence data, partially attributable t

229 e use among young PWID with probable serious mental illness (PSMI).

230 psychoactive drugs to patients with serious mental illness raises important ethical issues.

231 l risk factor of early-life social stress in mental illness, rearing rodents in persistent postweanin

232 Research shows that mental illness reduces employment and therefore income,

233 -1.16; P = 0.206) and a reduction in overall mental illness related hospitalizations (IRR 0.76, 95% C

234 g approach, we could automatically recognise mental illness-related posts in our balenced dataset wit

235 le lines of evidence suggesting that a major mental illness-related susceptibility factor, Disrupted

236 ion models, vignette portrayals of untreated mental illness, relative to the control condition, incre

237 the odds of BBVs in individuals with severe mental illness, relative to the general population, and

238 -cause mortality in people with a history of mental illness remained increased in multivariable analy

239 Victorian Government Mental Illness Research Fund.

240 from the Acknowledgements: 'Supported by the Mental Illness Research, Education and Clinical Center o

241 For ethnic minority groups with severe mental illness, residency in areas of higher own-group e

242 In the cohort with severe mental illness, residency in deprived, urban, and social

243 ified Poisson regression estimated perinatal mental illness risk between conception and 1 year postpa

244 ified Poisson regression estimated perinatal mental illness risk between conception and 1 year postpa

245 Perinatal mental illness risk was elevated in all classes versus w

246 Perinatal mental illness risk was elevated in all classes vs. wome

247 ion and perinatal strategies to reduce their mental illness risk.

248 ty, and systemic racism; what is the role of mental illness, robbery, and domestic violence; what is

249 aged 15-65 years with a diagnosis of severe mental illness (schizophrenia spectrum or bipolar disord

250 he smoking cessation intervention for severe mental illness (SCIMITAR+) trial, a pragmatic, randomise

251 causes long-lasting disturbances related to mental illness.SIGNIFICANCE STATEMENT Hypofrontality is

252 higher mortality rates in people with severe mental illness (SMI) may be partly due to inadequate int

253 was to assess the specific impact of severe mental illness (SMI) on the use of inpatient, emergency,

254 ty as an independent risk factor for serious mental illness (SMI) remains limited.

255 ened life expectancy in patients with severe mental illness (SMI), but efforts to predict cardiovascu

256 c stress exposure increases vulnerability to mental illness, so the ECSS has attracted attention as a

257 Among those with severe mental illness, some ethnic minorities have lower mortal

258 Mental illness stigma is a fundamental barrier to improv

259 ing protective against symptoms of the three mental illnesses studied, and the severity of flooding m

260 d history of domestic violence perpetration, mental illness, substance misuse, and suicide ideation o

261 s frequently report that patients with major mental illness such as schizophrenia and bipolar disorde

262 Major mental illnesses such as schizophrenia (SZ) and bipolar

263 People with severe mental illnesses such as schizophrenia are three times m

264 that white matter microstructure may play in mental illnesses, such as psychosis.

265 ion, with adaptations for people with severe mental illness-such as, extended pre-quit sessions, cut

266 rcome the modifiable determinants of adverse mental illness symptoms.

267 common denominator" risk factor for several mental illnesses, targets BDNF in disease-implicated bra

268 p<0.0001) times higher in people with severe mental illness than in the general population, whereas t

269 Schizophrenia is a debilitating mental illness that affects approximately 1% of the worl

270 ve social feedback is a prominent feature of mental illnesses that involve social anxiety.

271 ory pathway that is associated with multiple mental illnesses, the nonsense-mediated mRNA decay (NMD)

272 creased mortality from cancer in people with mental illness, this population receives less cancer scr

273 es should be developed to assist people with mental illness to undergo appropriate cancer screening,

274 are health services to patients with serious mental illness treated in community mental health settin

275 ssary to understand the relationship between mental illness treatment and stigmatizing attitudes in U

276 to assess the extent to which portrayals of mental illness treatment effectiveness influence persona

277 persons with mental illness, irrespective of mental illness type (adjusted risk ratios [ARRs] varied

278 from cancer, we assessed whether people with mental illness undergo less cancer screening compared wi

279 Patients were classified as having mental illness using International Classification of Dis

280 atio (OR) of cancer screening in people with mental illness versus the general population.

281 Overall prevalence of maternal mental illness was 23.2% (95% CI 23.1-23.4), which incre

282 ge 16 years, the cumulative risk of maternal mental illness was 53.1% (52.8-53.3).

283 History of mental illness was also associated with increased risk o

284 Probable serious mental illness was assessed using the Kessler-6 screenin

285 natural-cause mortality in those with severe mental illness was assessed.

286 amme, and year of ART initiation, history of mental illness was associated with increased risk of mor

287 Mental illness was associated with substantial excess mo

288 In England, prevalence of maternal mental illness was highest among children in the most de

289 The incidence of maternal mental illness was highest between 0-3 months (26.7 per

290 Stress Disorder 8 items (PTSD-8) and severe mental illness was measured with the Kessler Screening S

291 phically, the highest prevalence of maternal mental illness was observed in Northern Ireland (29.8%,

292 Patients who did and did not have mental illness were comparable relative to age and comor

293 ll-cause mortality in people with history of mental illness were greatest in patients retained in car

294 mpared with white British people with severe mental illness were similar (aRR 0.96, 95% CI 0.71-1.29)

295 c stress leads to greater CVD risk, multiple mental illnesses were associated with an increased risk

296 (BD) is a highly heritable and heterogeneous mental illness whose manifestations often include impuls

297 The rising public health burden of mental illnesses will inevitably exceed the capacity of

298 s-level neural activity linked to domains of mental illness with potential application to the develop

299 spring sex and presence of reported parental mental illness, with adjustment for covariates.

300 Severe mental illness, with clinical diagnosis obtained from in

301 site for therapeutic intervention in serious mental illness, yet we know very little about their dist