ライフサイエンスコーパス: mer

1 MerR acts as a repressor and activator of P (mer) .

2 long-lived kinetically trapped states (>=90-mer).

3 h k, a window length w and an order on the k-mers.

4 supports exact presence/absence queries of k-mers.

5 ty, which measures the sparsity of sampled k-mers.

6 been hospitalized with laboratory-confirmed MERS.

7 based on representing data sets as sets of k-mers.

8 to consensus fingerprints constructed from k-mers.

9 atic syntheses of polysaccharides as long 92-mers.

10 applied to the transcript-sequence-derived k-mers.

11 memory costs compared to methods that use k-mers.

12 ., SARS-1, Middle East respiratory syndrome [MERS]).

13 assemble and test the same enhancers as 192-mers, 354-mers and 678-mers and observe sizable differen

14 (SARS) and Middle East respiratory syndrome (MERS)(4,5).

15 -3') with 2'-O-methyl modifications and a 21-mer (5'-rCrArUrCrCrUrCrUrArGrArGrGrArUrArGrArArUrG-3'),

16 achieved 100% sequence coverage for both a 6-mer (5'-rGmUrArCmUrG-3') with 2'-O-methyl modifications

17 1, -A1*002, -B*008, and -B*017) to ~61,000 8-mer, 9-mer, and 10-mer peptides derived from the full pr

18 us communities in the Torres Strait Islands: Mer, a remote island where a traditional diet predominat

19 ients with Middle East respiratory syndrome (MERS), accounting for time-varying confounders.

20 dances at the scale of ~4 billion distinct k-mers across 2585 datasets.

21 ive repeats of this imperfectly conserved 11-mer amino acid motif.

22 he long-range interaction patterns between k-mers amino acids to predict protein crystallizability.

23 study the gas phase stability of the GroEL 7-mer and 14-mer complexes.

24 The 33-mer and P1 peptides showed no tendency regarding their a

25 tated four CD-active peptides, namely the 33-mer and peptides containing the DQ2.5-glia-alpha1a/DQ2.5

26 and test the same enhancers as 192-mers, 354-mers and 678-mers and observe sizable differences.

27 from 65 research articles on POCTs of SARS, MERS and COVID-19.

28 same enhancers as 192-mers, 354-mers and 678-mers and observe sizable differences.

29 fed at 100% maintenance energy requirements (MER) and the effect of sub-optimal restricted feeding on

30 002, -B*008, and -B*017) to ~61,000 8-mer, 9-mer, and 10-mer peptides derived from the full proteomes

31 COVID-19, 5/18 (28%) on SARS-1, 1/18 (6%) on MERS, and 3/18 (17%) on other coronaviruses.

32 other acute respiratory syndromes (COVID-19, MERS, and SARS).

33 (SARS) and Middle East respiratory syndrome (MERS) are speculated to have originated in bats.

34 single nucleotide variants, plastomes and k-mers associated with retrotransposons reveals two indepe

35 Ferrihydrite was fully reducible in MER at both pH(MER) of 5.0 and 7.5.

36 roves with increasing k-mer length for all k-mer based features.

37 Originally k-mer based, such tools often lack sensitivity when faced

38 Here we developed a new amino acid k-mer-based CAZyme classification, motif identification an

39 pecificity of taxonomic assignments and of k-mer-based clustering.

40 ent tools, ranging from ultra-fast low-RAM k-mer-based database search to fully exhaustive gapped DNA

41 at performs maximum likelihood analyses, a k-mer-based set difference algorithm, and random forest al

42 EC classification and annotation; (ii) the k-mer-based tools (including PPR-Hotpep, CUPP and eCAMI) p

43 Lastly, we confirmed that the k-mer-based tools have the unique ability to identify the

44 on into magnetite were accessible at both pH(MER) because the formed magnetite was not reducible unde

45 complex (IC), the template in the expanded 7-mer bubble positions the RNA and NTP analog UTPalphaS, w

46 All these A*02:01-restricted epitopes were 9-mers but, interestingly, we also identified and validate

47 ergence of Middle East Respiratory Syndrome (MERS) cases with a high case fatality rate stresses the

48 ltidomain protein that requires a minimum 12-mer chondroitin-4-sulfate molecule for specific, high af

49 of remdesivir treatment in the context of a MERS clinical trial.

50 as phase stability of the GroEL 7-mer and 14-mer complexes.

51 ctive of host taxonomy and that prediction k-mer composition improves with increasing k-mer length fo

52 feature sets were generated by extracting k-mer compositions and predicted protein domains.

53 s and protein levels in comparison to the 20-mer containing 223K during M. pneumoniae infection.

54 In both models, the 20-mer containing 223Q significantly decreased both tumor n

55 nstructing a network based on their shared k-mer content.

56 , in that OMH is sensitive not only to the k-mer contents of the sequences but also to the relative o

57 we tested the hypothesis that bat cells and MERS coronavirus (CoV) can co-exist in vitro.

58 Remdesivir (GS-5734) effectively inhibited MERS coronavirus (MERS-CoV) replication in vitro, and sh

59 iation of RBV/rIFN with 90-day mortality and MERS coronavirus (MERS-CoV) RNA clearance using marginal

60 rability, and immunogenicity of the GLS-5300 MERS coronavirus DNA vaccine in healthy adults.

61 neered a synthetic DNA vaccine targeting the MERS coronavirus Spike (S) protein, the major surface an

62 n (RBD) of Middle East respiratory syndrome (MERS) coronavirus spike, mediates viral entry using pseu

63 virus, and Middle East respiratory syndrome (MERS) coronavirus.

64 s well as the closely related SARS-CoV-1 and MERS coronaviruses, is restricted to BSL-3 facilities.

65 (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoVs) are zoonotic pathogens with h

66 rred sequences into input vectors based on k-mer counts.

67 S)-CoV and Middle East respiratory syndrome (MERS)-CoV are epidemic zoonotic CoVs that emerged at the

68 ructures that were antiviral against IAV and MERS-CoV along with the filoviruses Ebola and Marburg an

69 SARS-CoV-2 as well as the related SARS-CoV, MERS-CoV and endemic human coronaviruses (HCoVs).

70 The FSE-arch is conserved in the related MERS-CoV and is under purifying selection.

71 We infected cells from Eptesicus fuscus with MERS-CoV and maintained them in culture for at least 126

72 ant differences in FP Ca(2+) interactions of MERS-CoV and SARS-CoV FP despite their high sequence sim

73 miological investigation was conducted among MERS-CoV case patients (cases) and their household conta

74 munity clusters, and nosocomial outbreaks of MERS-CoV continue to occur.

75 ent could be attributed to Ca(2+) increasing MERS-CoV FP fusion-relevant membrane ordering.

76 ting with negatively charged residues in the MERS-CoV FP region.

77 hermal calorimetry showed an approximate 1:1 MERS-CoV FP to Ca(2+) ratio, as opposed to an 1:2 SARS-C

78 utant array in which E and D residues in the MERS-CoV FP were substituted with neutrally charged alan

79 SARS-CoV and MERS-CoV FPs share a high sequence homology, and here, w

80 By sequencing the whole genome of MERS-CoV from persistently infected bat cells, we identi

81 ng recombinant wild-type and ORF8b-deficient MERS-CoV further confirmed the suppressive role of ORF8b

82 investigated whether Ca(2+) is required for MERS-CoV fusion by screening a mutant array in which E a

83 Both SARS-CoV and MERS-CoV have caused serious outbreaks and epidemics in

84 h two major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012, respectively.

85 st SARS-CoV-2 that also inhibit SARS-CoV and MERS-CoV in vitro We found that 17 of these inhibit SARS

86 There are no approved treatments for MERS-CoV infection although a combination of lopinavir,

87 Additionally, the resistance to MERS-CoV infection directly correlated with increased se

88 MERS-CoV infection failed to elicit robust IFN response,

89 ber 2019, 2499 laboratory-confirmed cases of MERS-CoV infection, including 858 deaths (34.3% mortalit

90 vir treatment in a nonhuman primate model of MERS-CoV infection, the rhesus macaque.

91 flammatory cascade in human macrophages upon MERS-CoV infection.

92 o evidence of the potential for RDV to treat MERS-CoV infections.

93 domain of the MERS-CoV nucleocapsid protein (MERS-CoV N-NTD).

94 Here, we co-expressed the MERS-CoV nonstructural proteins nsp5, nsp7, nsp8, and ns

95 ic structure of the N-terminal domain of the MERS-CoV nucleocapsid protein (MERS-CoV N-NTD).

96 d and characterized type I IFN antagonism of MERS-CoV open reading frame (ORF) 8b accessory protein.

97 These VHHs neutralize MERS-CoV or SARS-CoV-1 S pseudotyped viruses, respective

98 is important for IKKepsilon activation, and MERS-CoV ORF8b suppresses type I IFN expression by compe

99 vancements made by studying the SARS-CoV and MERS-CoV outbreaks have provided a foundation for unders

100 developed in response to prior SARS-CoV and MERS-CoV outbreaks that can serve as resources for devel

101 ed drugs for this use for a fast response to MERS-CoV outbreaks.

102 r acts as a delayed RNA chain terminator for MERS-CoV polymerase complexes.

103 tein to study the mechanism of inhibition of MERS-CoV RdRp by RDV.

104 tion with the PDF2180 spike does not require MERS-CoV receptor DPP4 and antibodies developed against

105 MERS-CoV remains a high-threat pathogen identified by WH

106 induced clinical disease, strongly inhibited MERS-CoV replication in respiratory tissues, and prevent

107 MERS-CoV replication significantly upregulated C-type le

108 {CI}, .73-1.44]; P = .87) or with more rapid MERS-CoV RNA clearance (adjusted hazard ratio, 0.65 [95%

109 h reduction in 90-day mortality or in faster MERS-CoV RNA clearance.

110 e, we applied technology previously used for MERS-CoV to produce a prefusion-stabilized SARS-CoV-2 sp

111 at were persistently infected with DeltaORF5 MERS-CoV were resistant to superinfection by wildtype vi

112 monstrate that intracellular Ca(2+) enhances MERS-CoV wild-type (WT) PP infection by approximately 2-

113 oV) or Middle East respiratory syndrome CoV (MERS-CoV) also use bacterial components to modulate infe

114 a-CoVs Middle East respiratory syndrome-CoV (MERS-CoV) and SARS-CoV and the gamma-CoV infectious bron

115 S-CoV), Middle East respiratory coronavirus (MERS-CoV) and SARS-CoV-2, have been linked back to vario

116 iddle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavi

117 iddle East respiratory syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic vi

118 iddle East respiratory syndrome coronavirus (MERS-CoV) have revealed that delayed chain termination i

119 iddle East respiratory syndrome coronavirus (MERS-CoV) infections pose threats to public health world

120 iddle East respiratory syndrome coronavirus (MERS-CoV) is a highly pathogenic human coronavirus causi

121 iddle East respiratory syndrome coronavirus (MERS-CoV) is a lethal zoonotic pathogen that was first i

122 iddle East respiratory syndrome coronavirus (MERS-CoV) is a major emerging infectious disease with zo

123 iddle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a severe respiratory

124 iddle East respiratory syndrome coronavirus (MERS-CoV) poses a threat to public health.

125 iddle East respiratory syndrome coronavirus (MERS-CoV) poses an ongoing threat to public health world

126 734) effectively inhibited MERS coronavirus (MERS-CoV) replication in vitro, and showed efficacy agai

127 with 90-day mortality and MERS coronavirus (MERS-CoV) RNA clearance using marginal structural modeli

128 iddle East respiratory syndrome coronavirus (MERS-CoV) vaccines.

129 iddle East respiratory syndrome coronavirus (MERS-CoV) with eukaryotic proteins that may be potential

130 2) and Middle East respiratory syndrome CoV (MERS-CoV) within two decades(1-3).

131 iddle East respiratory syndrome coronavirus (MERS-CoV), and the most recently emerged SARS-CoV-2.

132 CoV-2, Middle East respiratory syndrome CoV (MERS-CoV), bat CoV HKU5 expressing the SARS-CoV-1 spike,

133 iddle East respiratory syndrome coronavirus (MERS-CoV), from less pathogenic coronaviruses.

134 iddle East respiratory syndrome coronavirus (MERS-CoV), the spike (S) protein is the main determinant

135 iddle East respiratory syndrome coronavirus (MERS-CoV), two other highly pathogenic coronavirus spill

136 iddle East respiratory syndrome coronavirus (MERS-CoV).

137 me-CoV and Middle East respiratory syndrome (MERS-CoV).

138 iddle East respiratory syndrome coronavirus (MERS-CoV).

139 iddle East respiratory syndrome coronavirus (MERS-CoV).

140 iddle East respiratory syndrome coronavirus (MERS-CoV).

141 iddle East respiratory syndrome coronavirus (MERS-CoV).

142 iddle East respiratory syndrome coronavirus (MERS-CoV).

143 her beta-coronaviruses, such as SARS-CoV and MERS-CoV, and might become an important tool for structu

144 ays, and cytokine secretion during SARS-CoV, MERS-CoV, and SARS-CoV-2 infection.

145 ined almost identical results with SARS-CoV, MERS-CoV, and SARS-CoV-2 RdRps.

146 with the related coronaviruses SARS-CoV and MERS-CoV, and the vast experience with other common RNA

147 e closely related coronavirus, SARS-CoV-1 or MERS-CoV, despite previous zoonotic outbreaks.

148 ighly pathogenic coronaviruses, SARS-CoV and MERS-CoV, have been controversial in terms of their prot

149 re no efficacious drugs and vaccines against MERS-CoV, increasing its potential to cause a public hea

150 V-HKU1) as well as severe illness and death (MERS-CoV, SARS-CoV, SARS-CoV-2).

151 coronavirus infection (SARS-CoV-2, SARS-CoV, MERS-CoV, seasonal coronaviruses).

152 stently infected cell culture model to study MERS-CoV-bat interactions.

153 h prior to inoculation completely prevented MERS-CoV-induced clinical disease, strongly inhibited ME

154 The MERS-CoV-induced proinflammatory response was evaluated

155 ating that RLR signaling also contributed to MERS-CoV-induced proinflammatory response.

156 ORF8b was abundantly expressed in MERS-CoV-infected Huh-7 cells.

157 ontribute to the proinflammatory response in MERS-CoV-infected macrophages.

158 The role of Mincle for MERS-CoV-triggered cytokine/chemokine induction was esta

159 f SKI genes inhibited replication of IAV and MERS-CoV.

160 cus on seasonal coronaviruses, SARS-CoV, and MERS-CoV.

161 ple CoVs, including SARS-CoV, SARS-CoV-2 and MERS-CoV.

162 at cells that are persistently infected with MERS-CoV.

163 The search terms also included SARS-CoV and MERS-CoV.

164 tissues contribute to high pathogenicity of MERS-CoV.

165 of evolutionary rates based on HCoV-OC43 and MERS-CoV.

166 In contrast to DENV, SARS and MERS CoVs predominantly infect respiratory epithelium, n

167 Here, we present the discovery of a 16-mer cyclic peptide that binds to Cdc42 with nanomolar af

168 However, because the k-mer distribution in eukaryotic genomes is highly uneven,

169 nment-free, stochastic models derived from k-mer distributions representing reference genome sequence

170 To this end, two 25-mer DNA aptamers, A1 and A2, were selected against the g

171 ncrease the melting temperature of both an 8-mer DNA duplex and a hairpin with a stem of 6-nt dependi

172 Particularly, the 7-mer DNA extension to crRNA is determined to be universal

173 ough minimal activation was observed with 80-mer duplex DNA, the optimal effector for Tel1 activation

174 SARS, MERS, Ebola, Nipah and an array of arenavirus infections

175 Lastly, the k-mer embedding space captured distinct k-mer profiles tha

176 on the current knowledge and perspectives on MERS epidemiology, virology, mode of transmission, patho

177 Among them, the 10-mer epitope located at the C-terminal end of the signal

178 dentified and validated an unusually long 16-mer epitope peptide restricted by A*02:01, HRVC(1791-180

179 When the n is given, the optional n-mer filter is applied with SIP and returns the near-nati

180 to export the location of all approximate k-mers for each genomic position.

181 Computing the uniqueness of k-mers for each position of a genome while allowing for up

182 ed analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyzed

183 cally ill patients with laboratory-confirmed MERS from 14 hospitals in Saudi Arabia diagnosed between

184 Minimizers are methods to sample k-mers from a string, with the guarantee that similar set

185 Identical k-mers from different regions provide 'seeds' for longer l

186 mpling while considering a weight for each k-mer; i.e. the higher the weight of a k-mer, the more lik

187 he short ICL-unhooked oligonucleotide (a six-mer in our study) by Pol eta providing a barrier to furt

188 ggest that the transcriptional regulation of mer in T. thermophilus is both similar to, and different

189 By comparing k-mers in a de novo assembly to those found in unassembled

190 ormation and flexibility of the individual n-mers in oligo-(9,9-dioctylfluorene) from controlled Suzu

191 aphs for k-mer indexing without losing any k-mers in the haplotypes.

192 nces but also to the relative order of the k-mers in the sequences.

193 rithm for simplifying variation graphs for k-mer indexing without losing any k-mers in the haplotypes

194 fficient to completely dissociate the Bfr 24-mer into protein dimers, and the reversibility and kinet

195 mic-most coupling domain of the otherwise 15-mer InvG oligomer.

196 vastly different light-switching properties: mer is "on", trans is "off", and cis switches from "off"

197 omputational analyses suggested that this 12-mer is highly labile and that apparent on-MHC trimming r

198 lized with Middle East respiratory syndrome (MERS) is unclear.

199 When the whole merR, including P (mer) , is removed, merA is transcribed from P (oah) inde

200 Gapped k-mer kernels with support vector machines (gkm-SVMs) have

201 k-mer composition improves with increasing k-mer length for all k-mer based features.

202 It is parameterized by the k-mer length k, a window length w and an order on the k-me

203 Boran cattle fed at sub-optimal and optimal MER levels and characterised their rumen microbial compo

204 ion of two Middle East respiratory syndrome (MERS)-like bat CoVs using exogenous protease treatment.

205 und that the spike protein of PDF2180-CoV, a MERS-like virus found in a Ugandan bat, could mediate in

206 the entire operon and a second promoter (P (mer) ), located within merR, is responsive to Hg(II).

207 We implemented this with rapid k-mer matching, which, when used on Oxford Nanopore MinION

208 Nubeam includes the k-mer method as a special case, but unlike the k-mer metho

209 r method as a special case, but unlike the k-mer method, it is convenient for Nubeam to account for G

210 icantly outperform shallow CNNs as well as k-mer methods in the discovery of tissue-specific sites bo

211 nge of nanoentity types and sizes (dimers, n-mers, micelles, colloids, etc.), each having their own u

212 tion, we show that the likelihood of a DNA 5-mer motif being targeted by SHM is not the same at diffe

213 Here, we use Skip-Gram word2vec to embed k-mers, obtained from 16S rRNA amplicon surveys, and then

214 e computed across multiple genomes where a k-mer occurrence is only counted once per genome.

215 as the reciprocal value of how often this k-mer occurs approximately in the genome, i.e. with up to

216 tinct pores that can each accommodate the 12-mer of chondroitin-4-sulfate, suggesting a model for rec

217 ting model sequences built from the unique k-mers of each of the reference sequences.

218 onotigs, which in a nutshell are groups of k-mers of similar abundances.

219 ydrite was fully reducible in MER at both pH(MER) of 5.0 and 7.5.

220 manner analogous to yeast and humans in a 25-mer oligonucleotide arising from incisions at 15 nt from

221 ity into the backbone such that a full PS 16-mer oligonucleotide is comprised of 215 distinct stereoi

222 Convergent block coupling of 30- and 31-mer oligosaccharide fragments, prepared by AGA, yielded

223 The mer operon of the deeply branching thermophile Thermus t

224 This activity is specified by the mer operon.

225 presenting an early step in the evolution of mer-operon regulation.

226 During the MERS outbreak in Korea, emergence and spread of viral va

227 , and esIgG(4) antibodies directed at 58 (15-mer) overlapping peptides, covering the entire sequence

228 health worldwide, making an understanding of MERS pathogenesis and development of effective medical c

229 therapy was commonly used in critically ill MERS patients but was not associated with reduction in 9

230 The studies of MERS patients with severe disease and experimentally inf

231 Of 349 MERS patients, 144 (41.3%) patients received RBV/rIFN (R

232 hemokine ligand (CCL) 8 and synthesized a 16-mer peptide (BK1.1) based on this interface region in ev

233 We show here that Stx2a binds to an 11-mer peptide (P11) mimicking the CTD of P stalk proteins

234 of HLA-DR1 presenting the immunodominant 20-mer peptide 5T4(111-130), combined with molecular dynami

235 We synthesized the 12-mer peptide and found that it binds the scFv antibody wi

236 tion-resistant gluten peptides (synthetic 33-mer peptide and pentapeptide epitopes) under static simu

237 A 25-mer peptide comprising the ED of MARCKS stimulates neuri

238 oupling of complex fragments, including a 20-mer peptide fragment analog of Exendin(9-39) on solid su

239 ertoires using a bacterial display random 12-mer peptide library and next-generation sequencing (NGS)

240 trophysiological recordings, leading to an 8-mer peptide that prevented alpha-Cbtx inhibition of nACh

241 In summary, we have identified a 7-mer peptide, (EP9) that binds to EpiSCs with high affini

242 bonds adjacent to proline residues in the 33-mer peptide.

243 While neither of the 20-mer peptides (223Q and 223K) had an effect on p38 phosph

244 a nested set of N-terminally extended 10-20-mer peptides (RA) (n) AAKKKYCL covalently bound to the h

245 and -B*017) to ~61,000 8-mer, 9-mer, and 10-mer peptides derived from the full proteomes of 82 SIV a

246 We screened a large set of random 30-mer peptides for AD function in yeast and trained a deep

247 also generalized to extract characteristic k-mer peptides for all the Swiss-Prot enzymes classified b

248 Chemoselective ligation of two 28-mer peptides has been accomplished using the Suzuki-Miya

249 an affinity tag or fluorescent probe into 20-mer peptides in >80% yield.

250 ptides in less than 35 minutes and 15- to 16-mer peptides in less than 20 minutes.

251 Automated flow synthesis produces 30-mer peptides in less than 35 minutes and 15- to 16-mer p

252 que ability to identify the characteristic k-mer peptides in the predicted enzymes.

253 NMR studies of two 14-mer peptides mimicking this region of the CT and its Ala

254 Synthetic overlapping 15-mer peptides of peanut allergens (Ara h 1-11) were spott

255 ts, five monoclonal antibodies (mAbs) and 18-mer peptides were generated.

256 ds of subfamilies each with distinguishing k-mer peptides.

257 the form of more than 172,000 overlapping 16-mer peptides.

258 ared by AGA, yielded a multiple-branched 151-mer polymannoside.

259 Blood platelets contain 60-100-mer polymers of phosphate groups called polyphosphate, a

260 lycan assembly (AGA) enables access to a 100-mer polysaccharide via a 201-step synthesis within 188 h

261 he k-mer embedding space captured distinct k-mer profiles that mapped to specific regions of the 16S

262 ombination, trimming of an HLA-B*08-bound 12-mer progressed at a considerable rate, albeit still slow

263 phine compound to a cysteine-substituted, 11-mer protein ring triggers supramolecular self-assembly,

264 builds upon LAVA by improving the speed of k-mer querying as well as the accuracy of the genotyping s

265 cell culture, the addition of a 3-O-S HS 12-mer reduced both tau cell surface binding and cellular u

266 _4 proteins that are characterized by the 11-mer repeat motif TAQAAKEKAXE.

267 These k-mers represented the characteristic motifs (in the form

268 ely, disease markers were more pronounced in Mer residents.

269 by 9.8%, 7.7%, and 7.1% for Na-, K-, and Cs-MER, respectively.

270 sphodiesterase catalytic activity toward a 5-mer RNA oligonucleotide containing a 2',3'-cyclic phosph

271 al a specific area of high glycan density on MERS S that results in the formation of oligomannose-typ

272 th coronavirus infection (defined as SARS-1, MERS, SARS-CoV-2, and other coronavirus) and bacterial/f

273 implementation of STing uses an innovative k-mer search strategy that eliminates the computational ov

274 ree assembly evaluation based on efficient k-mer set operations.

275 omputed between each sample represented as k-mer sets.

276 g nonprimed binding regions, and bicyclic 14-mer SFTI-1 analogues blocking both, primed and nonprimed

277 However, K-MER shows good uptake of CO(2) (3.5 mmol g(-1) at 1 bar

278 Multiple visualizations, such as k-mer spectrum plots, can be generated for evaluation.

279 or DPP4 and antibodies developed against the MERS spike receptor-binding domain and S2 portion are in

280 infected cells expressing coronavirus (SARS, MERS) spike as a biosecure alternative to assays involvi

281 is remarkably facilitated by a localized 16-mer stoichiometry in the periplasmic-most coupling domai

282 scalable algorithm for calculating gapped k-mer string kernels.

283 Disease outbreaks such as SARS, MERS, Swine Flu, Ebola, and COVID-19 (on-going) have cau

284 ell-documented regulation of proteobacterial mer systems, possibly representing an early step in the

285 PDP-Nal is a 23 mer that binds to PP1 through several interactions.

286 or probe design by identifying approximate k-mers that are unique to a genome or that are present in

287 UNCALLED probabilistically considers k-mers that could be represented by the signal and then pr

288 -CoV-1 and Middle East respiratory syndrome (MERS), the development of therapeutic antibodies and vac

289 ach k-mer; i.e. the higher the weight of a k-mer, the more likely it is to be selected.

290 ion of antibodies to SARS-CoV-2, SARS-CoV-1, MERS, three circulating coronavirus strains (HKU1, 229E,

291 generate optimal-length peptides (i.e. 8-10-mers) to fit into the MHC class I groove.

292 , and the tyrosine kinases of the TAM family Mer tyrosine kinase (MerTK)/Axl.

293 In addition, mer-[V(ddpd)(2)][PF(6)](3) shows very strong blue fluore

294 Here, we report the vanadium(III) complex mer-[V(ddpd)(2)][PF(6)](3) yielding phosphorescence arou

295 ive virus challenge of animals given SARS or MERS vaccines resulted in vaccine hypersensitivity react

296 eloped a unit of protein structure-a van der Mer (vdM)-that maps the backbone of each amino acid to s

297 By down-weighting frequently occurring k-mers, we are able to meet both objectives: (i) avoid exc

298 ospitalized adults with laboratory-confirmed MERS were randomly assigned to receive recombinant inter

299 ng, with the guarantee that similar set of k-mers will be chosen on similar strings.

300 Merlinoite zeolite (topology type MER) with Si/Al = 3.8 has been prepared in Na, K, and Cs