ライフサイエンスコーパス: mercapto

1 By blocking the Au film surface with 11-Mercapto-1 -undecanol (MCU), nonspecific adsorption of A

2 and 4-(4 -chlorobenzylideneimino)-3-methyl-5-mercapto-1,2,4-triazole (CBIMMT) as the reagent.

3 in milk and infant formulas using 3-amino-5-mercapto-1,2,4-triazole capped gold nanoparticles (AMTr-

4 aldehyde with Purpald (4-amino-3-hydrazino-5-mercapto-1,2,4-triazole) works under alkaline conditions

5 itive reagent Purpald (4-amino-3-hydrazino-5-mercapto-1,2,4-triazole), serves as a quick and inexpens

6 n easily accessible organic ligand 2-amino-5-mercapto-1,3,4-thiadiazole (AMT) with silver nitrate.

7 of aromatic/heterocyclic sulfonamides and 5-mercapto-1,3,4-thiadiazoles were investigated as LdcCA i

8 romatic/heterocyclic sulfonamides and some 5-mercapto-1,3,4-thiadiazoles were investigated as TcCA in

9 distinct carboxyl-functionalized molecule 3-mercapto-1-adamantanecarboxylic acid.

10 yers based on 11-mercapto-1-undecanol and 16-mercapto-1-hexadecanethiol (2.1 and 2.9 nm, respectively

11 igher than the sensor passivated with only 6-mercapto-1-hexanol ( approximately 1.5).

12 er of 11-mercaptoundecanoic acid (MUA) and 6-mercapto-1-hexanol (1:3 mole ratio) and covalently conju

13 MMP), 3-(mercapto)hexyl acetate (3MHA) and 3-mercapto-1-hexanol (3MH) are compounds potentially respo

14 roup, i.e., 3-mercapto-1-propanol (3-MPL), 6-mercapto-1-hexanol (6-MHL), 8-mercapto-1-octanol (8-MOL)

15 nucleic acid (ssDNA) as anchored probe and 6-Mercapto-1-hexanol (MCH) as blocking agent on the platin

16 trategy by introducing both the target and 6-mercapto-1-hexanol (MCH) into the aptamer immobilization

17 onolayer of specific thiolated aptamer and 6-mercapto-1-hexanol (MCH), whose ratio was optimized by e

18 ed of AuNPs, particular MMP substrates and 6-mercapto-1-hexanol (MCH).

19 A novel sensor design with 6-mercapto-1-hexanol (MCH)/1-pyrenebutanol (PBA) blocking

20 Cys-3MH) precursors of the varietal thiols 3-mercapto-1-hexanol and 3-mercaptohexyl acetate, characte

21 ved by modification of gold electrode with 6-mercapto-1-hexanol following monolayer self-assembly of

22 evers in the array are functionalized with 6-mercapto-1-hexanol SAMs to eliminate the influence of en

23 single-stranded DNA (SH-(CH(2))(6)-ssDNA)/6-mercapto-1-hexanol system formed on a silver surface is

24 protected clusters (C6 MPCs) and dissolved 6-mercapto-1-hexanol thiol (HOC6SH) increase with increasi

25 tized, single-stranded oligonucleotide and 6-mercapto-1-hexanol.

26 onger and more passivating diluent such as 6-mercapto-1-hexanol.

27 DNA labeled at 5'end using 6-mercapto-1-hexhane (HS-ssDNA) is immobilized on the PPy-

28 nol (6-MHL), 8-mercapto-1-octanol (8-MOL), 9-mercapto-1-nonanol (9-MNL), 11-mercapto-1-undecanol (11-

29 nol (3-MPL), 6-mercapto-1-hexanol (6-MHL), 8-mercapto-1-octanol (8-MOL), 9-mercapto-1-nonanol (9-MNL)

30 ith the maytansinoid N(2')-deacetyl-N(2')-(3-mercapto-1-oxopropyl)-maytansine (DM1), a potent antimic

31 he maytansinoid DM1 (N(2')-deacetyl-N(2')-(3-mercapto-1-oxopropyl)-maytansine), a potent antimicrotub

32 cene (11-mercaptoundecyl), and ferrocene (11-mercapto-1-oxoundecyl), are studied on amorphous and sin

33 Li and Li[SCH2C(O)N(H)Ph] ([Tm(Ph)] = tris(2-mercapto-1-phenylimidazolyl)hydroborato ligand).

34 We identify different populations of 3-mercapto-1-propanesulfonate (MPSA)-modified-gold NPs usi

35 with the -OH terminating head group, i.e., 3-mercapto-1-propanol (3-MPL), 6-mercapto-1-hexanol (6-MHL

36 e bearing a covalently linked monolayer of 3-mercapto-1-propanol, a modified surface that blocks the

37 olate complexes that are supported by tris(2-mercapto-1-t-butyl-imidazolyl)hydroborato ligation, name

38 Specifically, the tris(2-mercapto-1-t-butylimidazolyl)hydroborato ligand [Tm(Bu(t

39 made up of mixtures of the trimethylsilyl-11-mercapto-1-undecane ether and various proportions of the

40 Here, we report on the development of 11-mercapto-1-undecanesulfonate-coated gold nanoparticles (

41 ol (8-MOL), 9-mercapto-1-nonanol (9-MNL), 11-mercapto-1-undecanol (11-MUL) and another blocking thiol

42 ining a short alkylthiol surface diluent [11-mercapto-1-undecanol (MCU)] on gold supports.

43 m) and self-assembled monolayers based on 11-mercapto-1-undecanol and 16-mercapto-1-hexadecanethiol (

44 s of either 11-mercaptoundecanoic acid or 11-mercapto-1-undecanol using 1-ethyl-3-[3-(dimethylamino)p

45 ons of the hydroxyl-terminated mercaptan (11-mercapto-1-undecanol).

46 nolayers with 11-mercaptoundecanoic acid, 11-mercapto-1-undecanol, decanethiol, and a covalently link

47 lk using cold plasma, and modified with N-(2-mercapto-1H-benzo[d]imidazole-5-yl) oleamide; combined s

48 5-Mercapto-2,2'-bithiophene (BTSH) functionalized copper (

49 In sharp contrast to 3NTF, both 3TF and 3-mercapto-2-(4-(trifluoromethyl)phenyl)-4H-chromen-4-one

50 ves through reaction of the enolate ion of 3-mercapto-2-butanone.

51 N-(2-mercaptoethyl)porfiromycin (12), 7-N-(2-mercapto-2-methylpropyl)mitomycin C (13), and 7-N-(3-mer

52 deoxycholic acid, spermidine, lysine, and 5-mercapto-2-nitrobenzoic acid, have been synthesized and

53 inylphenol, guaiacol, sotolon and 4-methyl-4-mercapto-2-pentanone.

54 othiaphospholes have been synthesized from 1-mercapto-2-phosphinobenzene and a variety of acid chlori

55 Two thiols, 2-mercaptoethanol and mercapto-2-propanol, were poorer substrates than CoM, wh

56 The calpain inhibitor (2)-3-(4-iodophenyl)-2-mercapto-2-propenoic acid (PD150606) also inhibited the

57 rted in a one-pot process to (2S)-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid mono

58 )Fe(CO)(2)('S')], (1) (H(2)xbsms = 1,2-bis(4-mercapto-3,3-dimethyl-2-thiabutyl)benzene) is converted

59 )-bis-(1-propenyl) disulfides, and (Z)/(E)-2-mercapto-3,4-dimethyl-2,3-dihydrothiophenes accounting f

60 ously reported that compound 2 (N-[[1-[(2(S)-mercapto-3-methyl-1-oxobutyl) amino]-1-cyclopentyl]-carb

61 (E)-4-Mercapto-3-methylbut-2-en-1-yl diphosphate is a reversib

62 -3-methylbut-2-en-1-yl diphosphate and (E)-4-mercapto-3-methylbut-2-en-1-yl diphosphate.

63 g potency and selectivity and shows that the mercapto-3-phenylpropanoyl backbone is significantly bet

64 Three mercapto-3-phenylpropanoyl inhibitors were synthesized,

65 irst, a modeled binding mode for inhibitor 2-mercapto-3-phenylpropionyl-RATKML (K(i) = 330 nM) was ge

66 The docked conformation of 2-mercapto-3-phenylpropionyl-RATKML was then used to refin

67 A variety of 1-mercapto-3-yn-2-ols 5 (readily available from alkynylati

68 A variety of readily available 1-mercapto-3-yn-2-ols 5 were conveniently converted into t

69 -mercaptocyclopentane arylsulfonamide, and 3-mercapto-4-arylsulfonamidopyrrolidine matrix metalloprot

70 f the key building block (3R,4E)-3-hydroxy-7-mercapto-4-heptenoic acid, a mild Mitsunobu macrolactoni

71 Varietal thiols such as 4-mercapto-4-methyl-2-pentanone (4MMP), 3-(mercapto)hexyl

72 hyl phenylacetate) and varietal compounds (4-mercapto-4-methyl-2-pentanone, 3-mercaptohexylacetate, b

73 -mercaptohexan-1-ol (3MH) and particularly 4-mercapto-4-methylpentan-2-one (4MMP) are highly potent f

74 rcaptohexan-1-ol, 3-mercaptohexyl acetate, 4-mercapto-4-methylpentan-2-one), roasted coffee (2-furfur

75 We observed the S-4-mercapto-4-methylpentan-2-one-l-cysteinyl-glycine (CysGl

76 ne-l-cysteinyl-glycine (CysGly-4MMP) and S-4-mercapto-4-methylpentan-2-one-N-(l-gamma-glutamyl)-l-cys

77 D cleaved synthetic MMP substrates Ac-PLG-[2-mercapto-4-methylpentanoyl]-LG-OEt and Mca-PLGL-Dpa-AR-N

78 (3TF), namely, 2-(4-(diethylamino)phenyl)-3-mercapto-4H-chromen-4-one (3NTF), which possesses an -S-

79 tively identified by mass spectrometry as 5'-mercapto-5'-deoxyadenosine, generated by direct attack o

80 3-Mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid (1

81 dinuclear rhodium complex with the anionic 2-mercapto-6-methylpyridinate (mmp) bridging ligand is rep

82 o-7-methylpurine ribonucleoside to 2-amino-6-mercapto-7-methylpurine by purine nucleoside phosphoryla

83 s substrate and a manual assay and 2-amino-6-mercapto-7-methylpurine ribonucleoside (MESG) as substra

84 then detected by the conversion of 2-amino-6-mercapto-7-methylpurine ribonucleoside to 2-amino-6-merc

85 o-9(Z)-octadecenoic acid (S-12-HSODE), 12(R)-mercapto-9(Z)-octadecenoic acid (R-12-HSODE), and 12-mer

86 ing hydrophobic thiols: 1-octanethiol, 12(S)-mercapto-9(Z)-octadecenoic acid (S-12-HSODE), 12(R)-merc

87 mide, so is 2-aminothiazole formed from beta-mercapto-acetaldehyde and cyanamide in water at neutral

88 elationships between glycolaldehyde and beta-mercapto-acetaldehyde, and the corresponding proteinogen

89 ct of radiometal chelate on biodistribution, mercapto-acetyl diglycine (MAG(2)) was compared with die

90 luate split renal function (SRF) with Tc-99m-mercapto-acetyltriglycin (MAG3) scintigraphy in living k

91 ing length thiolated nucleic acids and short mercapto alcohols on gold surfaces under repeated electr

92 ough a linker-assisted methodology that uses mercapto alkanoic acids as the organic linkers.

93 development of beta, beta-disubstituted-beta-mercapto-alpha-amino acids as AcH-sequestering agents.

94 nal nature and remarkable specificity of the mercapto and alkoxysilane functions for metal and zeolit

95 ), while the vasopressin antagonist, l-(beta-mercapto-beta beta-cyclopentamethylene propionic acid) 2

96 ssin and the vasopressin antagonist [l-(beta-mercapto-beta, beta-cyclopentamethylene propionic acid)

97 lving attack by the free thiol of the 1-beta-mercapto-beta, beta-cyclopentamethylenepropionic acid (P

98 entrations of AVP were inhibited by [1-(beta-mercapto-beta,beta,-pentamethylenepropionic acid),2-0-me

99 pid monolayers were constructed by using the mercapto derivatives of natural lipids that were self-as

100 orresponding alpha-mercapto ketones or alpha-mercapto esters) were smoothly converted into the corres

101 Co-methyl-5-hydroxybenzimidazolylcobamide:2-mercapto-ethanesulphonic acid methyltransferase (MtaA).

102 ne, Glutathione, 3-mercaptopropionic acid, 2-mercapto ethanol, and cysteamine).

103 The addition of beta-mercapto-ethanol to the reaction mixture produces thiol

104 Under the conditions employed, 8-mercapto-FAD (pK(a) = 3.8) and 8-hydroxy-FAD (pK(a) = 4.

105 presence of pOHB, PHBH reconstituted with 8-mercapto-FAD also shows the additional oxidized intermed

106 In these investigations, we have used 8-mercapto-FAD and 8-hydroxy-FAD to probe the movement of

107 kinetic analysis of PHBH substituted with 8-mercapto-FAD demonstrated that the apparent k(cat) is al

108 -N5-sulfite adduct and p-quinonoid form of 8-mercapto-FAD), Ile430-N, Thr431-N, and Thr431-OG are hyd

109 Here, we devise a mercapto-functionalized mesoporous silica layer as a sup

110 hydration of the keto group and the exposed mercapto group attacks on C1 resulting in departure of t

111 As an approach to assess the ability of a mercapto group to serve as a functional analogue for the

112 based ligands, those containing the simplest mercapto group, hydrosulfide ion (HS(-)), are significan

113 , one a primary amino group and the second a mercapto group, were prepared and tested for their compa

114 e introduced nanoporous carbon modified with mercapto groups as a new solid-phase method for extracti

115 This study reports the synthesis of the mercapto-hapten (S)-N-(2-(mercaptoethyl)-6-(3-(2-(methyl

116 , a precursor to the coenzymes coenzyme B (7-mercapto heptanoylthreonine phosphate) and biotin, has b

117 lution, followed by co-immobilization with 6-mercapto-hexane onto the gold electrodes to control the

118 6-mercapto hexyl-oligonucleotides bind to a gold surface s

119 s 4-mercapto-4-methyl-2-pentanone (4MMP), 3-(mercapto)hexyl acetate (3MHA) and 3-mercapto-1-hexanol (

120 stals were grown from solutions containing 6-mercapto-IMP and GTP, the electron density at the active

121 in concert to stabilize the 6-thioanion of 6-mercapto-IMP, which in turn is the nucleophile in the di

122 from alkynylation of the corresponding alpha-mercapto ketones or alpha-mercapto esters) were smoothly

123 ances, compositae-sesquiterpene lactone mix, mercapto mix-mercaptobenzothiazole, carba mix-thiuram mi

124 Mercapto-modified graphene oxide (GO-SH) can be applied

125 e quaternary amine present in thiocholine (2-mercapto-N,N,N-trimethyl-ethanaminium) in conjunction wi

126 coupling 2,5-dichloro-4-nitroaniline with 2-mercapto-N,N-dimethylbenzamide.

127 effect of a novel series of S-substituted 6-mercapto-N-phenyl-nicotinamides on CXCL1-stimulated Ca(2

128 The obtained capacities of mercapto-nanoporous carbon were found to be 145 and 95 m

129 thioether 4,6-bis[4-[[2-(dimethylamino)ethyl]mercapto]phenyl]pyrimidine (1a) and amide 4,6-bis(4[(2-(

130 We report a practical 2-hydroxy-3-mercapto-propionic acid (Hmp)/2-methylpiperidine (2-MP)

131 etylcysteine, 2-mercaptoethanesulfonic acid, mercapto-propionyglycine, and cysteamine can directly se

132 S-methylation of thiopurine drugs such as 6-mercapto-purine, 6-thioguanine and azathioprine.

133 -L (NHC = N-heterocyclic carbene L = Cl or 2-mercapto-pyrimidine) have been synthesized and structura

134 A structure of the enzyme bound to a 2-mercapto-quinazolinone inhibitor shows that the compound

135 r groups in free or protected form (hydroxy, mercapto, S-acetylthio, and Se-acetylseleno) for attachm

136 Mercapto (-SH) groups in these ligands interact with cat

137 Briefly, mercapto-terminated peptide nucleic acid (PNA) was first

138 4-amino-trans-proline, and Mpt and Mpc for 4-mercapto-trans- and -cis-prolines, respectively.

139 of 1-3 and 14-16 nm diameter stabilized by 1-mercapto-undecane-11-tetra(ethyleneglycol) has been demo

140 and low molecular weight chitosan bonded to mercapto undecanoic acid.

141 ne MT-2 with MDL28170 and 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid (PD 150606), two calpain-s

142 d its inhibitor PD150606 (3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid) complex were determined w