ライフサイエンスコーパス: mesenchyme

1 in which DR was contained within the portal mesenchyme.

2 eposition of matrix proteins by an activated mesenchyme.

3 ignaling and the extracellular matrix in the mesenchyme.

4 the primary cilia in the CNC-derived palatal mesenchyme.

5 ies and modulatory roles of the fibroblastic mesenchyme.

6 rea of proliferation of the neighboring root mesenchyme.

7 comprised of smooth muscle and peri-urethral mesenchyme.

8 nactive state broadly across the distal limb mesenchyme.

9 hyaluronic acid accumulation in the palatal mesenchyme.

10 master control gene expressed in pericloacal mesenchyme.

11 licifolia isolectin B4 (IB4) in the cephalic mesenchyme.

12 letion in cell culture and developing kidney mesenchyme.

13 xpression pattern in female VMP and prostate mesenchyme.

14 n in forebrain neuroectoderm and frontonasal mesenchyme.

15 tes nephron development from the metanephric mesenchyme.

16 h to coordinate growth and patterning in gut mesenchyme.

17 Dkk2, in the maxillary and mandibular tooth mesenchyme.

18 pe" the epithelium downwards into underlying mesenchyme.

19 ding Dkk2 and Sfrp2, in the developing tooth mesenchyme.

20 f2c, Sox6, and Sp7 in the developing palatal mesenchyme.

21 d decreased cell proliferation in the distal mesenchyme.

22 antly upregulated in the Osr2 mutant palatal mesenchyme.

23 adhesion in the PS epithelia and underlying mesenchyme.

24 of the Shh signaling pathway in the palatal mesenchyme.

25 on defects characterized by a thickened lung mesenchyme.

26 spatial and transcriptional map of the lung mesenchyme.

27 hrough sonic hedgehog (SHH) signaling to the mesenchyme.

28 0.5 murine epithelial progenitors and native mesenchyme.

29 3a and Sema3d genes in the embryonic palatal mesenchyme.

30 transition in cultured isolated metanephric mesenchyme.

31 stinct cellular identities within the dental mesenchyme.

32 mpaired protein glycosylation in the palatal mesenchyme.

33 l invasion into the surrounding adipose-rich mesenchyme.

34 ized cell behaviour intrinsically within the mesenchyme.

35 l transducer Smo in either pp endoderm or NC mesenchyme.

36 h endoderm and neighboring neural crest (NC) mesenchyme.

37 epelling Slit2/3 signals from the pancreatic mesenchyme.

38 ron bone at the lateral edges of the ventral mesenchyme.

39 ries and inhibits ECM assembly in the tissue mesenchyme.

40 that invaginate and bud into the underlying mesenchyme.

41 nd instructive cues from the surrounding gut mesenchyme.

42 proliferative expansion of the adjacent lung mesenchyme.

43 ributes to the inductive potential of dental mesenchyme.

44 f Wnt-induced epithelium into the underlying mesenchyme.

45 ral coloboma, and a deficiency of periocular mesenchyme.

46 g murine airway epithelium in the absence of mesenchyme.

47 lating the inductive potential of the dental mesenchyme.

48 ically within the second heart field-derived mesenchyme.

49 tracellular matrix components in the palatal mesenchyme.

50 from preformed blood vessels in the cephalic mesenchyme.

51 ulfate accumulation in the posterior palatal mesenchyme.

52 d in the corresponding region of the palatal mesenchyme.

53 nce during regeneration of new hair follicle mesenchyme.

54 ociation of villous epithelium from adjacent mesenchyme.

55 th muscle that is derived from the embryonic mesenchyme.

56 ased apoptosis in the developing frontonasal mesenchyme.

57 ocal interactions between the epithelium and mesenchyme.

58 ate receptors were expressed entirely in the mesenchyme.

59 m but a moderate to weak level in the dental mesenchyme.

60 eriderm, basal epithelial cells and adjacent mesenchyme.

61 ttern the oral-aboral axis of the mandibular mesenchyme.

62 nic signature in endothelium, pericytes, and mesenchyme.

63 n both the neuroepithelium and the overlying mesenchyme.

64 ium continuously extends into the underlying mesenchyme.

65 pendent expression in the developing palatal mesenchyme, 88 contained or were located next to Foxf2-b

66 ibution of rat PSCs to the mouse metanephric mesenchyme, a nephron progenitor.

67 Lung mesenchyme also contains other poorly described cell typ

68 al organ that develops from undifferentiated mesenchyme, although the mechanisms that regulate the de

69 n with enhancers active in the proximal limb mesenchyme and antagonizes the repressive function of TA

70 e developing human airway surrounded by lung mesenchyme and cells expressing alveolar-cell markers.

71 PDGFRalpha and PDGFRbeta in the craniofacial mesenchyme and demonstrate that the receptors form funct

72 m layers; the lateral plate mesoderm-derived mesenchyme and ectoderm-derived surface epithelium.

73 stribution of viscoelastic properties within mesenchyme and epithelia.

74 29(K326X/+) embryos showed confluent palatal mesenchyme and epithelium at e18.5 ( n = 16), and no mic

75 lthough Fgfr3 and Fgfr4 are expressed in the mesenchyme and epithelium, inactivation in the mesenchym

76 n to enteric neurons but also on the enteric mesenchyme and epithelium; 3) a muscle genetic program e

77 ctive mechanical properties of the embryonic mesenchyme and establish engineering strategies for more

78 ic gene changes in the mTORC1-activated lung mesenchyme and establishes the importance of the WNT sig

79 oles of YAP/TAZ in endodermal epithelium and mesenchyme and find that, although dispensable for gastr

80 istinct cell-cell communication network with mesenchyme and macrophages during repair.

81 ideas about the contributions of mesodermal mesenchyme and neural crest to particular structures.

82 nations were constructed using avian hindgut mesenchyme and non-intestinal epithelium from the bursa

83 ription factor is highly expressed in dental mesenchyme and preodontoblasts, while in mature, secreto

84 anisms regulating persistence of nephrogenic mesenchyme and provides a rationale for therapies aimed

85 nalyses of the apical ectodermal ridge, limb mesenchyme and skeletal muscle.

86 Here we present evidence that fin mesenchyme and striated tail muscle in both animals are

87 eliminated, whereas the arrival of cephalic mesenchyme and stromal choroid plexus BAMs was only part

88 al signaling among the ureteric tubules, cap mesenchyme and surrounding stromal mesenchyme to orchest

89 e Wnt/beta-catenin/Bmp4 axis (in the stromal mesenchyme) and Bmp4/p63 signaling (in the epithelium) p

90 number upstream of Shh-dependent (posterior mesenchyme) and Shh-independent, cilium-based (anterior

91 del to study interactions across epithelium, mesenchyme, and nerves.

92 interactions between both the epithelium and mesenchyme are required for normal morphogenesis.

93 h do not arise exclusively from neural crest mesenchyme as previously thought.

94 deleted Yap/Taz throughout the palatal shelf mesenchyme as well as specifically in the posterior pala

95 function that demonstrates a redeployment of mesenchyme-associated developmental genes.

96 Forkhead box F1 (FOXF1) is a lung embryonic mesenchyme-associated transcription factor that demonstr

97 lia are located in the dental epithelium and mesenchyme at early stages of tooth development and late

98 cell proliferation in dental epithelium and mesenchyme at embryonic day 16.5; however, the cell apop

99 e inner enamel epithelium and the underlying mesenchyme at the early bell stage, as exhibited by targ

100 ranscription factor II) in the Wolffian duct mesenchyme became intersex-possessing both female and ma

101 etected Shroom3 expression in the condensing mesenchyme, Bowman's capsule, and developing and mature

102 senchyme and epithelium, inactivation in the mesenchyme, but not the epithelium, recapitulated the de

103 servation between mouse and human pancreatic mesenchyme by testing identified mesenchymal factors in

104 al morphogenesis is prevented in the ventral mesenchyme by the concomitant induction of osteogenesis

105 and Tbx3 maintain proliferation of the lung mesenchyme by way of at least two molecular mechanisms:

106 sruptions to either the matrix or periocular mesenchyme can cause defects in early eye development, y

107 Because ectodermal and mesodermal mesenchyme can form in close proximity and give rise to

108 ge or specifically in the developing palatal mesenchyme caused reduced palatal shelf size and increas

109 Later ablation of T-box3 in posterior limb mesenchyme causes digit loss.

110 nditional inactivation of Tak1 or Jun in cap mesenchyme causes identical phenotypes characterized by

111 ced palatal shelf size and increased palatal mesenchyme cell density prior to the time of normal pala

112 icating that Jag1-Notch1 signaling restricts mesenchyme cell proliferation non-cell autonomously.

113 The primary mesenchyme cells (PMCs) are the cells that are responsib

114 um carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown p

115 The skeleton-forming primary mesenchyme cells (PMCs) of euechinoid sea urchins, deriv

116 that interactions between Pou3f4-expressing mesenchyme cells and SGNs are important for proper axon

117 signaling in UGS increases proliferation of mesenchyme cells and suppresses androgen-induced prolife

118 show that although cultured embryonic dental mesenchyme cells are unable to induce tooth formation, t

119 In this study, we isolated palatal mesenchyme cells from embryonic day 12.5 (E12.5) and E13

120 aws involves patterning neural crest-derived mesenchyme cells into distinct subpopulations along the

121 redicted by the model, ablation of secondary mesenchyme cells late in archenteron elongation does not

122 Overall, these data suggest that otic mesenchyme cells may play a role in maintaining SGN popu

123 Remarkably, when only mesenchyme cells surrounding postnatal GPs were killed,

124 Here we use cultured limb mesenchyme cells to assess the response of the target Ho

125 ut to investigate if the failure of cultured mesenchyme cells to form bioengineered teeth might be re

126 they inhibit the ability of embryonic dental mesenchyme cells to induce tooth formation.

127 at4 influences signaling from stromal to cap mesenchyme cells to regulate their differentiation into

128 h E12.5 and E13.5 in the Osr2(RFP/-) palatal mesenchyme cells, in comparison with Osr2(RFP/+) litterm

129 s1 in mice leads to increased numbers of cap mesenchyme cells, which are abnormally arranged around t

130 nglion neurons (SGNs) are surrounded by otic mesenchyme cells, which express the transcription factor

131 y, Dchs1 is required specifically within cap mesenchyme cells.

132 ial tension due to the activity of secondary mesenchyme cells.

133 +) self-renewing progenitors and loss of cap mesenchyme (CM) integrity.

134 phron progenitor pool, called the condensing mesenchyme (CM).

135 The mesenchyme contacts newborn TVCs and contributes to robu

136 odel and clear from the fusion site to allow mesenchyme continuity.

137 y controlling keratinocytes and keratinocyte-mesenchyme cross-talk via hemichannel and endoplasmic re

138 e bone deposition in the premaxillary suture mesenchyme curtailed overall growth, leading to midfacia

139 ifferentiate into forelimb- or hindlimb-type mesenchymes, depending on a concentration of retinoic ac

140 ferent influence on niche dynamics than does mesenchyme derived Wnt.

141 r positive, which is consistent with both MD mesenchyme-derived cells and the purported importance of

142 s and mathematical simulations, we find that mesenchyme-derived GDF10 and GREM1 are major controllers

143 ar derivatives, the embryonic origin of many mesenchyme-derived tissues is still unclear.

144 ferent growth factors with known activity in mesenchyme-derived tissues.

145 conditions and, with the inclusion of native mesenchyme, develop into pancreatoids expressing markers

146 longed to muscle cell differentiation and to mesenchyme development and differentiation.

147 ational change in the cytoskeletal system of mesenchyme dictates the maintenance and differentiation

148 e Erk2 deletion is restricted to the palatal mesenchyme, did not display cleft palate, suggesting tha

149 ombined with HIOs in vitro migrated into the mesenchyme, differentiated into neurons and glial cells

150 re alternatively spliced as the fetal kidney mesenchyme differentiates into tubular epithelium will i

151 ocal interactions between the epithelium and mesenchyme, diverse integumentary organs form and underg

152 development emerge from the ooze of primary mesenchyme during gastrulation.

153 on of the distal endoderm and the underlying mesenchyme during lung branching morphogenesis, but litt

154 sis in the neural crest-derived craniofacial mesenchyme during palatogenesis in mice.

155 ering the dorsoventral character of the limb mesenchyme elicits a change in the profile of propriocep

156 tion of polarity results in an epithelial-to-mesenchyme (EMT) transition and possible increased metas

157 by the presence of androgens and subsequent mesenchyme-epithelial interactions.

158 ly promoted by COUP-TFII, which suppresses a mesenchyme-epithelium cross-talk responsible for Wolffia

159 ch Ift88 is lost specifically in the palatal mesenchyme, exhibit isolated cleft palate.

160 at the developing mandibular molar tooth bud mesenchyme expresses significantly higher levels of Dkk2

161 later, cells in the leaflet/annulus junction mesenchyme expressing inactive NFATC1 (5.5-9 weeks) were

162 xpression of Vcan, and the migration of lung mesenchyme fibroblasts, and suggest that alveolar sac fo

163 evelopmental stage 15 when osteochondrogenic mesenchyme forms condensates for each plastron bone at t

164 fferentiation protocol for the generation of mesenchyme-free HIOs that can be primed towards more col

165 estinal progenitors and robust generation of mesenchyme-free organoids expressing characteristic mark

166 G mutations show a pre-induction metanephric mesenchyme gene expression pattern and are significantly

167 ium (NGE), and between GE and the underlying mesenchyme (GM) were enriched in multiple GO terms and K

168 f SHH signaling in either the endoderm or NC mesenchyme had direct and indirect effects on both cell

169 genesis-suppressing cell fate in the ventral mesenchyme has permitted turtles to develop their order-

170 and Shh-independent, cilium-based (anterior mesenchyme) Hedgehog pathway function.

171 ox C1 (Foxc1), paired box 3 (Pax3), Paraxis, mesenchyme homeobox 1 (Meox1), sine oculis-related homeo

172 vates expression of the transcription factor mesenchyme homeobox 1 (MEOX1).

173 idermis requires signals from the underlying mesenchyme; however, the specific pathways involved rema

174 are associated with reduced proliferation of mesenchyme in developing nasal processes and adjacent ti

175 riptomic analysis of changes in ectoderm and mesenchyme in Esrp1(-/-) embryos during face formation.

176 upregulated and expanded into the tooth bud mesenchyme in Inhba(-/-) embryos in comparison with wild

177 similated by the urogenital sinus primordial mesenchyme in males during fetal development.

178 opically activated in the developing palatal mesenchyme in Osr2(-/-) embryos.

179 ficiently differentiate into the metanephric mesenchyme in rat, allowing the generation of mouse PSC-

180 (DEGs) were found between the epithelium and mesenchyme in the base of oral cavity as compared to the

181 tiotemporal expression in the epithelium and mesenchyme in the developing tooth.

182 within the primary cilia of the CNC-derived mesenchyme in the lip and palate region in mice and is a

183 m, lens, and neural crest-derived periocular mesenchyme induced severe eye abnormalities with high pe

184 in II contractility drives the smooth dermal mesenchyme into a pattern of surface bumps that triggers

185 eered ureteric bud tissue also organized the mesenchyme into smooth muscle that spontaneously contrac

186 agination of epithelium into the surrounding mesenchyme is a critical step that marks the development

187 ell-cell interactions between epithelium and mesenchyme is a potential approach to address this pheno

188 Mesenchyme is an embryonic precursor tissue that generat

189 It is generally accepted that the inductive mesenchyme is capable of inducing the odontogenic commit

190 on of Inhba and Bmp4 in the developing tooth mesenchyme is independent of each other, Bmp4(ncko/ncko)

191 However, the mesenchyme is known to guide epithelial morphogenesis an

192 phenotype, but WNT activation alone in lung mesenchyme is not sufficient for the development of mous

193 feration of cranial neural crest cell (cNCC) mesenchyme is required for upper lip closure.

194 The mesenchyme is the main component of the embryonic pancre

195 A key downstream target in the mesenchyme is Zfh1/ZEB.

196 re predominantly expressed in the pancreatic mesenchyme, is required and sufficient for islet morphog

197 on of Wnt5a is observed in mutant pancreatic mesenchyme, leading to subsequent loss of expression of

198 More importantly, deletion of Ctnnb1 in the mesenchyme leads to the loss of basal cells and cartilag

199 ditional inactivation of Porcn in periocular mesenchyme led to defects in mid- and hindbrain and in c

200 signaling in neural crest-derived mandibular mesenchyme led to expansion of BMP signaling activity to

201 , and laminin, suggestive of transition to a mesenchyme-like phenotype.

202 nce cell interactions between epithelial and mesenchyme-like tissues coordinate liver bud formation a

203 Endothelial-to-mesenchyme-like transition (Endo-MT) of trabecular meshw

204 nine kinase 11), in the fetal Mullerian duct mesenchyme (MDM), the caudal remnant of which is thought

205 attacking the host immune response through a mesenchyme-mediated immune control (MMIC) mechanism.

206 ecified in vegetal epithelium, transition to mesenchyme, migrate, and re-enter ectoderm, distributing

207 In the mesenchyme, Nrp1 colocalized with capillary-rich tissue.

208 those UB-like structures into peri-Wolffian mesenchyme of cultured kidney rudiments can induce produ

209 erges early in development, primarily in the mesenchyme of developing salivary glands.

210 n the dental follicle/sac and dental papilla mesenchyme of developing teeth and in odontoblasts and t

211 DGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablat

212 zation showed that Dlx4 was expressed in the mesenchyme of the murine palatal shelves at E12.5, prior

213 Expression of HOXA5 protein in mesenchyme of the respiratory tract and in phrenic motor

214 liferation was reduced in the branchial arch mesenchyme of Yap and Taz CNC conditional knockout (CKO)

215 Mesenchyme originates from both mesoderm and the neural

216 ed proliferation in the medial nasal process mesenchyme paralleled the domain of reduced Foxf2 and Gl

217 cal Wnt signaling, in the developing palatal mesenchyme, particularly in the posterior regions of the

218 In contrast, ablation of Hoxa5 in mesenchyme perturbed trachea development, lung epithelia

219 ular glycosaminoglycan in developing palatal mesenchyme, plays a major role in palatal shelf elevatio

220 es hedgehog (Hh) signaling in the periocular mesenchyme (POM) canonically activated by choroid-secret

221 eavage, we show that Notch activation in the mesenchyme precedes specification into pdgfrb (high) MCs

222 growth, whereas epithelium-produced FGF9 and mesenchyme-produced FGF10 guide lung epithelial developm

223 the acute phase of epithelial injury as the mesenchyme proliferates in response, but returns to base

224 ng subsequently restrains Bmp-mediated valve mesenchyme proliferation by sustaining Hbegf-EGF recepto

225 geting of Foxf2 by Shh signaling drives cNCC mesenchyme proliferation during upper lip morphogenesis,

226 Significantly, the negative regulator of mesenchyme proliferation, Hbegf, was markedly reduced in

227 dysmorphology was associated with increased mesenchyme proliferation, indicating that Jag1-Notch1 si

228 that downstream of Gli the Foxf1+ splanchnic mesenchyme promotes medial constriction of the foregut a

229 chondrocytes, osteoblasts, and craniofacial mesenchyme ( Prx1-cKO) would phenocopy skeletal and dent

230 nductive interactions between epithelium and mesenchyme regulate gut development, but the influence o

231 bited smaller and compressed alveoli and the mesenchyme remained thick and hyperplastic.

232 ated interactions between the epithelium and mesenchyme required for normal lung development can be d

233 essed in the midline neuroepithelium and the mesenchyme respectively, causes dorsal midline Bmp signa

234 ifically in developing palatal or mandibular mesenchyme, respectively, using Wnt1-Cre, Osr2-Cre, and

235 essed in the developing lateral craniofacial mesenchyme, retina and sensory ganglia.

236 R) and RNA sequencing on lung epithelium and mesenchyme retrieved by laser capture microdissection.

237 l partial inactivation of Fgfr2b in the lung mesenchyme reveal the involvement of both receptors in l

238 scopy within the zebrafish paraxial mesoderm mesenchyme reveals a physical association between Integr

239 Bmp signal reception in either epithelium or mesenchyme reveals that Bmp signaling in Hh-responsive m

240 icrocirculation could be reconfigured by the mesenchyme-selective growth factor, FGF9.

241 The suture mesenchyme serves as a growth centre for calvarial morph

242 extend, tenascin C (TNC) accumulates in the mesenchyme several cell diameters away from the epitheli

243 We conclude that prostate inductive mesenchyme shows limited cellular heterogeneity and that

244 Thus, modulation of endoderm/mesenchyme signalling emerges as a plausible mechanism l

245 Specific endoderm/mesenchyme signalling is required for stomach differenti

246 Here, we found that lung mesenchyme-specific deletion of CDH-implicated genes enc

247 Here we identify that exosomes loaded with mesenchyme-specific mature microRNA contribute mobile ge

248 s or blockade of AT2-specific Stat3, Bdnf or mesenchyme-specific TrkB compromised repair and reduced

249 and Wnt, and 'inhibitor' Hh, whereas BMP and mesenchyme-specific-FGF signalling were incorporated onc

250 form across the bifurcation site as the cap mesenchyme splits.

251 n formation; when grafted into peri-Wolffian mesenchyme, still attached to a kidney rudiment or in is

252 stage-matched MCs, i.e., septum transversum mesenchyme (STM), in 2D cultures.

253 ither the otic epithelium or its surrounding mesenchyme suggest that Sema signaling could be involved

254 5a lineage also contributes to the pulmonary mesenchyme, suggesting that Wnt5a/PCP is a molecular cir

255 oth upregulated in neural crest cell-derived mesenchyme surrounding Meckel's cartilage and in the pal

256 Here we document that the V (mem) of limb mesenchyme switches from a hyperpolarized to depolarized

257 Fibroblast growth factor 9, a mesenchyme-targeting growth factor, enhanced ASC differe

258 decoupling of the germ layer origins of the mesenchyme that forms the calvarial bones from inductive

259 ectomesenchyme predominates in the salivary mesenchyme that immediately surrounds the budding epithe

260 al plate coelomic epithelium gives rise to a mesenchyme that populates the pleuroperitoneal folds iso

261 ively, when recombined with fetal mouse lung mesenchyme, the cells recapitulated epithelial-mesenchym

262 k2 than the developing maxillary molar tooth mesenchyme, these data indicate that Bmp4 and activin si

263 e collagen crosslinking in the palatal shelf mesenchyme, thus controlling palatal shelf elevation, as

264 requires GDNF signaling from the surrounding mesenchyme to cells at the ureteric bud tips, via the Re

265 Later, sNCCs enter the colon mesenchyme to colonize and contribute to the intrinsic i

266 ion of the elastogenic machinery in the lung mesenchyme to control orderly formation of the elastin E

267 tion factors act within the mouse pancreatic mesenchyme to define a pro-endocrine specialized niche.

268 including Bmp4 and Fgf3, in the early tooth mesenchyme to drive tooth morphogenesis through the bud-

269 deletion in cap mesenchymal cells abolishes mesenchyme to epithelial transition (MET) that is linked

270 mary, exosomal transport of miR-133b-3p from mesenchyme to epithelium decreases DIP2B, which may func

271 roRNA contribute mobile genetic signals from mesenchyme to epithelium.

272 h-threshold response genes in the underlying mesenchyme to form a signaling center called the "villus

273 genes Tbx2 and Tbx3 act together in the lung mesenchyme to maintain branching morphogenesis.

274 ules, cap mesenchyme and surrounding stromal mesenchyme to orchestrate complex morphogenetic events.

275 ce production of urothelium and organize the mesenchyme to produce rhythmically contracting smooth mu

276 , loaded into exosomes, was transported from mesenchyme to the salivary epithelium, which did not exp

277 through Bmp signalling from the interdigital mesenchyme, to regulate specification of joint progenito

278 ment, and induction of pathogenic epithelial-mesenchyme transition (EMT).

279 cation region in the posterior palatal shelf mesenchyme upon deletion of Yap/Taz.

280 ing plasma B-cells, were detected within the mesenchyme, urothelium, and follicular aggregates in the

281 otein core of proteoglycans, from the dental mesenchyme using Osr2-Cre, which is also strongly expres

282 model in which PTH1R is ablated in the limb mesenchyme using Prx1Cre transgenic mice.

283 terizing the heterogeneity of the intestinal mesenchyme using single-cell RNA-sequencing analysis, we

284 specifically in the posterior palatal shelf mesenchyme, using the Osr2(Cre) and Col2(Cre) drivers, r

285 class II+, or CD11b+ immunocytes in the skin mesenchyme was increased, and essentially no subcutis de

286 signals were long obscure because intestinal mesenchyme was insufficiently characterised.

287 In addition, ectopic FGFR activation in mesenchyme was sufficient to increase sensory progenitor

288 To identify pathways active in mesenchyme we used tissue and single cell transcriptomic

289 f the NF-kappaB pathway specifically in lung mesenchyme, we utilized the mesenchymal Twist2-Cre to dr

290 subset analysis showed that VMP and adjacent mesenchyme were composed of distinct cell types and that

291 ssion in enterocytes and IL-13 expression in mesenchyme were diminished.

292 tudy, PrSPCs mixed with rat urogenital sinus mesenchyme were grafted under the renal capsule of nude

293 cells, IL-25 in epithelium and IL-13 in the mesenchyme were significantly reduced, but Tm burden was

294 r polarity within the early pre-chondrogenic mesenchyme, when skeletal shape is established, and prov

295 g (Shh) is expressed in the distal posterior mesenchyme, where it acts as a mediator of anterior to p

296 ates the proliferative expansion of the lung mesenchyme, whereas inactivation of hedgehog signalling

297 mic retinoic acid (RA) landscapes in feather mesenchyme, which modulate GREM1 expression and epitheli

298 sion of morphogenetic genes in inductive UGS mesenchyme, which promotes proliferation and cytodiffere

299 ffinities intrinsically change in the distal mesenchyme, which we suggest results in a gradient of po

300 as derivatives of a continuous, dual-origin mesenchyme with common skeletogenic competence, and that