ライフサイエンスコーパス: mesocortical

1 tures may be part of the neurobiology giving mesocortical afferents their hormone sensitivities and/o

2 ted with trait anxiety, as well as increased mesocortical and decreased mesohippocampal coupling.

3 hese 5-HT1A-mediated actions of 5-HT include mesocortical and mesolimbic dopaminergic neurons having

4 ntipsychotics that may differentially target mesocortical and mesolimbic dopaminergic neurons having

5 , driven by motivational signals through the mesocortical and mesolimbic pathways, which help sustain

6 g revealed that kappa2 receptors localize to mesocortical and subcortical limbic areas, including the

7 einforcement are influenced by mesostriatal, mesocortical, and mesolimbic dopamine systems.

8 holaminergic "nigrostriatal," "mesolimbic," "mesocortical," and spinal cord projections arising from

9 ens (mesolimbic circuit) and frontal cortex (mesocortical circuit).

10 zophrenia, dysfunction in the mesolimbic and mesocortical circuits and their corresponding glutamater

11 These findings reveal that mesocortical DA can facilitate dissociable components of

12 thium were mediated by BNDF signaling in the mesocortical DA circuit.

13 ulation secondary to sustained deficiency in mesocortical DA function.

14 t this impairment relates to a deficiency in mesocortical DA function.

15 ereas the adjacent A10 region mesolimbic and mesocortical DA neurons are relatively spared.

16 In contrast, short burst stimulation of mesocortical DA neurons that produced transient (<4 s) D

17 sequences, and the delayed maturation of the mesocortical DA pathway.

18 ther, these results demonstrated the role of mesocortical DA projection in antidepressive-like effect

19 eal an additional level of complexity in how mesocortical DA regulates different forms of cognition v

20 We conclude that while baseline mesocortical DA synthesis is indeed dependent on tyrosin

21 t tobacco smoking differentially affects the mesocortical DA system in men vs. women, suggesting a po

22 cing effects of tobacco smoking, whereas the mesocortical DA system-including the dorsolateral prefro

23 ) receptors potentiate the phasic release of mesocortical DA.

24 Mesocortical DAT immunoreactivity in motor, premotor, an

25 s at early Parkisnon's disease stages, while mesocortical degeneration mediated increases of ineffici

26 A) receptors modulate the functioning of the mesocortical dopamine (DA) pathway.

27 Mesocortical dopamine (DA) regulates a variety of cognit

28 rontal cortex (PFC) and are modulated by the mesocortical dopamine (DA) system.

29 However, why and how mesocortical dopamine axon density increases across adol

30 Our findings indicate that a group of mesocortical dopamine axons encodes aversive-related sig

31 hese findings suggest that the depression of mesocortical dopamine axons that follows gonadectomy is

32 st in part, from a paucity of DAT content in mesocortical dopamine axons, as well as a distribution o

33 tion to investigate how rats' mesolimbic and mesocortical dopamine circuits contribute to the express

34 Disrupted mesocortical dopamine contributes to cognitive symptoms

35 in cognition, the specific contributions of mesocortical dopamine depletion and striatal dysfunction

36 an hamsters; Phodopus sungorus) we find that mesocortical dopamine development can be regulated by a

37 e present data suggest that the influence of mesocortical dopamine neurons on the dopamine projection

38 task-related changes previously observed in mesocortical dopamine neurons, which have been implicate

39 uction of sensitization, suggesting that the mesocortical dopamine pathway is not involved in the acu

40 f cortical/prefrontal cortical function, the mesocortical dopamine system.

41 from animal studies that the mesolimbic and mesocortical dopamine systems are sensitive to circulati

42 ion who study the role of the mesolimbic and mesocortical dopamine systems that originate in the vent

43 resentations of reward to the mesolimbic and mesocortical dopamine systems, thereby initiating motiva

44 oss of CB1R-mediated retrograde signaling on mesocortical dopamine transmission, and, in turn, altere

45 es in corticocortical, corticobasal ganglia, mesocortical dopamine, and cerebellar-thalamic-prefronta

46 nous input to both regions, for example from mesocortical dopamine, or separate and consecutive stage

47 eads to selective abnormalities in postnatal mesocortical dopaminergic maturation and behavioral abno

48 pecific period of maturation and function of mesocortical dopaminergic neurons and their sensitivity

49 The epigenetic changes in the mesocortical dopaminergic neurons were prevented when an

50 r impact on cognitive functions modulated by mesocortical dopaminergic neurons.

51 epressants, which act through enhancement of mesocortical dopaminergic signaling.

52 ntral tegmental area, and activation of this mesocortical dopaminergic system decreases spontaneous a

53 c projections to motor cortices, whereas the mesocortical dopaminergic system facilitates working mem

54 In contrast, mesocortical dopaminergic transmission appears well pres

55 function as a direct consequence of impaired mesocortical dopaminergic transmission or an indirect co

56 with a parallel shift toward mesolimbic and mesocortical function.

57 an animal model that affects mesolimbic and mesocortical function.

58 These findings reveal a distinct mesocortical glutamatergic pathway that critically modul

59 tion that paralleled established patterns of mesocortical hormone sensitivity, including the androgen

60 inergic cell group, reminiscent of recurrent mesocortical loops described in mammals.

61 on of dopamine signaling may be an important mesocortical mechanism contributing to its ability to ai

62 estimates of DA utilization and synthesis in mesocortical, mesolimbic and nigrostriatal DA terminal r

63 correlated with increased activation in the mesocortical-mesolimbic reward circuitry encompassing th

64 ely labeled dopaminergic and nondopaminergic mesocortical neurons projecting to prefrontal, premotor,

65 ning mesoaccumbens neurons and DA-containing mesocortical neurons suggests novel mechanisms through w

66 , have been linked to changes in mesolimbic, mesocortical neurotransmitter systems utilizing biogenic

67 and Lewis rats have selective differences in mesocortical, nigrostriatal and mesolimbic DA neuronal r

68 related to hypodopaminergic activity in the mesocortical pathway and prefrontal cortex, are predicti

69 development of the DA system, especially the mesocortical pathway involved in action adaptation to ru

70 Dysfunction in the mesocortical pathway, connecting the ventral tegmental a

71 rcuitry, e.g., mesostriatal, mesolimbic, and mesocortical pathways.

72 pathways: the nigrostriatal, mesolimbic, and mesocortical pathways.

73 hich form the nigrostriatal, mesolimbic, and mesocortical pathways.

74 th origins of nigrostriatal, mesolimbic, and mesocortical projections are consistent with identified

75 he proportions of dopamine neurons making up mesocortical projections were approximately 30% in males

76 ssing in the prefrontal cortex (PFC) through mesocortical projections.

77 oral systems, progressing from mesolimbic to mesocortical regions and from latent to patent behaviors

78 island (6 layers) separated by a surrounding mesocortical ring (4-5 layers) from a peripheral allocor

79 l rats point to the regulatory influences on mesocortical serotonin circuits in highly aggressive ani

80 sterior bed nucleus of the stria terminalis, mesocortical structures and the hippocampal formation.

81 m neurons may implicate VPvm in facilitating mesocortical structures with information related to the

82 We suggest that the mesocortical system might transmit fast signals about re

83 nd electrochemical measures to show that the mesocortical system produces a fast non-DA-mediated post

84 onia-like behavioral responses to bupropion, mesocortical tyrosine hydroxylase (TH) expression, chron

85 RAIC projections to mesolimbic/mesocortical ventral forebrain circuits are likely to pa