ライフサイエンスコーパス: mesonephric

1 calized to mesenchymal precursors within the mesonephric and metanephric kidney and is subsequently d

2 nephric mesenchyme and proper demarcation of mesonephric and metanephric mesenchyme from the WD depen

3 es and a common origin shared between caudal mesonephric and metanephric nephrons.

4 elia and is essential for the development of mesonephric and metanephric tubules and caudal extension

5 scular cells migrate into the gonad from the mesonephric border along with endothelial cells and that

6 carcinomas including clear cell, serous, and mesonephric carcinomas (0/6).

7 t affect inhibition of germ cell meiosis and mesonephric cell migration but caused defects in Leydig

8 We show that, although mesonephric cell migration cannot be induced into normal

9 From these results, we conclude that mesonephric cell migration plays a critical role in the

10 In each case, mesonephric cell migration was abnormal.

11 We tested the hypothesis that mesonephric cell migration was impaired in three cases r

12 ductions in characteristic XY proliferation, mesonephric cell migration, and fetal Leydig cell differ

13 eatment induced germ cell meiosis, inhibited mesonephric cell migration, and had no effect on Leydig

14 Sry to stimulate mesenchymal proliferation, mesonephric cell migration, and Sertoli cell differentia

15 wn that some testis-specific events, such as mesonephric cell migration, can be experimentally induce

16 We propose that BMP signaling promotes mesonephric cell survival within the genital ridges and

17 e coincident, supporting the hypothesis that mesonephric cells are critical for cord development.

18 Here we show that mesonephric cells are required for cord formation and ma

19 Migration of mesonephric cells occurred into XY but not XX gonads fro

20 To investigate the contribution of mesonephric cells to this process, gonads from wild-type

21 Adult tmem67 zebrafish developed progressive mesonephric cysts that share conserved features of mamma

22 leles, and these Osr1-knockouts died with no mesonephric duct development shown by histochemical stai

23 ns, the knockout efficiencies increased, and mesonephric duct development with EGFP-positive cells wa

24 hus, a failure of development of mesonephros/mesonephric duct gives rise to absent ureters and hence

25 rt a mechanical dependency linking gonad and mesonephric duct morphogenesis.

26 We report a close alignment of gonad and mesonephric duct movements as well as delayed duct devel

27 ression has been documented in the Wolffian (mesonephric) duct, the mesonephros, metanephros and feta

28 y position and spatial relationship with the mesonephric ducts, kidneys and adrenals.

29 ogenital tract involving Mullerian ducts and mesonephric ducts.

30 As per Acien, Wolffian (mesonephric) ducts instead of Mullerian ducts and sinova

31 se establish epithelial primordia within the mesonephric (embryonic) and metanephric (adult) kidneys

32 We show that WNT4 represses mesonephric endothelial and steroidogenic cell migration

33 8s, a gonadal lineage located at the gonadal-mesonephric interface.

34 We find trpm7 expression in the mesonephric kidney and show that mutants develop kidney

35 ells correlated with decreased levels of the mesonephric marker, Pax2, as well as a reduction in gene

36 Timely regression of mesonephric mesenchyme and proper demarcation of mesonep

37 may arise from the mesonephric tubules, the mesonephric mesenchyme, or the coelomic epithelium.

38 d to increased somatic cell death within the mesonephric mesenchyme.

39 xpressed in the Wolffian duct but not in the mesonephric mesenchyme.

40 ter gene and the underlying nephrogenous (or mesonephric) mesenchyme with chemical dyes.

41 proposed to derive from mesenchymal cells of mesonephric origin.

42 eriments, not the migration of pronephric or mesonephric precursor cells from the primitive streak.

43 ally, persistent expression of Odd1 in chick mesonephric precursor cells inhibits differentiation of

44 k embryo, Odd1 can promote expression of the mesonephric precursor markers Pax2 and Lim1.

45 e staining and staining of the aorto-gonadal-mesonephric region, which is known to host vascular prec

46 an duct elongates along the Wolffian duct, a mesonephric structure that is required for Mullerian duc

47 reveals that Foxc1 homozygotes have ectopic mesonephric tubules and ectopic anterior ureteric buds.

48 arb2-Cre was used to eliminate FGF8 from the mesonephric tubules but to allow expression in the adjac

49 Additionally, Hoxd11(+) mesonephric tubules exhibit an altered morphology and ac

50 is essential to the outgrowth of the cranial mesonephric tubules from the Wolffian duct and to the de

51 ules, indicating that Fgf8 expression by the mesonephric tubules is required specifically for the for

52 duct degenerated prematurely and the cranial mesonephric tubules were missing.

53 blast growth factor 8 (Fgf8) is expressed in mesonephric tubules, but its role in this tissue remains

54 omatic cells of the gonad may arise from the mesonephric tubules, the mesonephric mesenchyme, or the

55 expressed lacZ exclusively in renal tubules, mesonephric tubules, ureteric bud, developing ureter, an

56 in the intermediate mesoderm, nephric duct, mesonephric tubules, ureteric bud, pretubular aggregates

57 ressed in developing nephrons, ureteric bud, mesonephric tubules, Wolffian duct, and Mullerian duct.

58 larly shows deficient Lhx1 expression in the mesonephric tubules.

59 nsable for the formation of nephric duct and mesonephric tubules.

60 ite patterning, and ectopic and disorganized mesonephric tubules.

61 ages are associated with nascent gonadal and mesonephric vasculature during the initial phases of tes

62 nism beginning with breakdown of an existing mesonephric vessel.