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1 s in response to physiologic stimuli (termed metabolic flexibility).
2 al Ca(2+) uptake during activity and achieve metabolic flexibility.
3 nsulin and positively correlated with IS and metabolic flexibility.
4 e context of cellular thiamine synthesis and metabolic flexibility.
5 increased reliance on glycolysis and reduced metabolic flexibility.
6 and opportunists is strongly associated with metabolic flexibility.
7 st, we found that the heart had considerable metabolic flexibility.
8 on of mitochondrial respiration with limited metabolic flexibility.
9 tion, dysfunction, and global impairments in metabolic flexibility.
10 g metabolic memory, despite achieving modest metabolic flexibility.
11 the TCA cycle, providing further evidence of metabolic flexibility.
12 ment, this process provides tumor cells with metabolic flexibility.
13 alcium signaling, which are crucial for TNBC metabolic flexibility.
14 h mutant plants, demonstrating their lack of metabolic flexibility.
15 r are unavailable, thereby ensuring neuronal metabolic flexibility.
16 h the evolution of mammalian hibernation and metabolic flexibility.
17 ile type of immune cells exhibits remarkable metabolic flexibility.
18 ar phagocytes which occurs at the expense of metabolic flexibility.
19 ulated molecular architecture for hepatocyte metabolic flexibility.
20 lic adaptation to this stressor and maintain metabolic flexibility.
21  not done so constitutively, consistent with metabolic flexibility.
22                   This may also affect one's metabolic flexibility.
23 activity levels are a primary determinant of metabolic flexibility.
24 he PDK isoform that is a potent modulator of metabolic flexibility.
25 lular energy metabolism, suggesting neuronal metabolic flexibility.
26 sired metabolic cross-talk while maintaining metabolic flexibility.
27  acyclic terpenes, suggesting a reduction of metabolic flexibility.
28 hways, and improving insulin sensitivity and metabolic flexibility.
29 rs from metabolic bystander to key driver of metabolic flexibility.
30  in the fed state, contributing to a loss of metabolic flexibility.
31  may thus participate in the preservation of metabolic flexibility.
32 r to IPGR, but less active while maintaining metabolic flexibility.
33 reby allowing the heart to maintain its full metabolic flexibility.
34 ulin sensitive, and active while maintaining metabolic flexibility.
35 is for how NAD(+) homeostasis factors confer metabolic flexibility.
36 mental approaches to studying the concept of metabolic flexibility across a range of activity and ina
37             However, the key determinants of metabolic flexibility among relevant clinical population
38 ineered cell lines, which revealed a lack of metabolic flexibility and a contribution of the 3q29 gen
39 ompensatory fashion, which may contribute to metabolic flexibility and a growth advantage to sustain
40 r levels of thiamin vitamers for the plant's metabolic flexibility and ability to acclimate to an alt
41 es a potential mechanism for the increase in metabolic flexibility and enhanced insulin sensitivity p
42 eview, we provide a contemporary view of the metabolic flexibility and functional plasticity of skele
43                                              Metabolic flexibility and glucose flux were examined in
44     High fat feeding impairs skeletal muscle metabolic flexibility and induces insulin resistance, wh
45 c state of adipocytes, and enhances systemic metabolic flexibility and insulin sensitivity.
46 tine production is essential for maintaining metabolic flexibility and insulin sensitivity.
47       Our findings highlight C. closterium's metabolic flexibility and its potential role in global c
48 hat the gene ech-6 is potential modulator of metabolic flexibility and may be a target for promoting
49                               To investigate metabolic flexibility and oxygen delivery in the failing
50 acterium stems from its genomic variability, metabolic flexibility and phenotypic diversity, enabling
51 ibility was inversely correlated with IS and metabolic flexibility and positively correlated with bod
52  the importance of muscle PDH in maintaining metabolic flexibility and preventing the development of
53 e sedentary behaviours as therapy to improve metabolic flexibility and reduce weight gain risk.
54 dial glucose uptake and oxidation reduce the metabolic flexibility and render the heart susceptible t
55                           Recovery relies on metabolic flexibility and stress-adaptive mechanisms, su
56 ify how OPA1 up-regulation allows AML cells' metabolic flexibility and survival and nominates specifi
57 in cancer stem cell reprogramming to promote metabolic flexibility and tumor initiation.
58 eight loss, improved glucose homeostasis and metabolic flexibility, and better mobility and strength.
59  because of their small genome size, reduced metabolic flexibility, and high worldwide abundance in f
60 ice, abolished diurnal rhythms in whole body metabolic flexibility, and increased markers of adverse
61 he regulatory mechanisms and significance of metabolic flexibility are not completely understood.
62 re, BEZ-treated mice also exhibited improved metabolic flexibility as well as an enhanced mitochondri
63 ricted feeding partially restored whole body metabolic flexibility, as well as day-night differences
64 sion of pyruvate transport induces a form of metabolic flexibility associated with the use of lipids
65              Loss of insulin sensitivity and metabolic flexibility can result in cardiovascular disea
66  organisms that have substantial genetic and metabolic flexibility, can resist multiple classes of an
67                                      Loss of metabolic flexibility, characterized by the impaired cap
68 sensitive to malonyl-CoA, displaying reduced metabolic flexibility compared to younger animals.
69 e most salient feature of the network is the metabolic flexibility demonstrated in response to variou
70 onnected through homologous recombination, a metabolic flexibility despite a small genome size, and a
71           Fasting RQ and DeltaRQ, reflecting metabolic flexibility, did not differ after both diets.
72                                              Metabolic flexibility enables fungi to invade challengin
73 and aquatic) green alga that has significant metabolic flexibility for balancing redox equivalents an
74                    The role of mitochondrial metabolic flexibility for CD8(+) T cell immune response
75                  This alga shows an enormous metabolic flexibility, growing either photoautotrophical
76                             Although loss of metabolic flexibility has been proposed to play a causal
77                                         This metabolic flexibility has important implications for the
78                     Laboratory assessment of metabolic flexibility has traditionally involved measure
79             RYGB surgery results in improved metabolic flexibility (ie, greater disposal of glucose a
80                These results reveal that the metabolic flexibility imparted by the stroma-derived ace
81 port demonstrating the general importance of metabolic flexibility in cell health.
82                                              Metabolic flexibility in fuel use observed in obese chil
83 ma cell production, but reveal an unexpected metabolic flexibility in hexose requirements.
84      However, the regulation and function of metabolic flexibility in lymphatic endothelial cells (LE
85    We will also discuss how the ETC enhances metabolic flexibility in methanogens and can even permit
86  directly regulates MPC activity to modulate metabolic flexibility in mice.
87 ectively, our study identified a key role of metabolic flexibility in modulating the effect of FGFR s
88                Whilst the heart retains some metabolic flexibility in non-ischaemic cardiomyopathy, w
89 xposure in early pregnancy programs impaired metabolic flexibility in offspring, which may increase s
90 glucose metabolism, insulin sensitivity, and metabolic flexibility in overweight adults (aged 45-65 y
91 ncoded in the genome, suggesting significant metabolic flexibility in oxidizing NADH under a variety
92 al muscle mitochondrial substrate choice and metabolic flexibility in part by regulating PDH function
93 reen alga Chlamydomonas reinhardtii displays metabolic flexibility in response to a changing environm
94          We examined individual variation in metabolic flexibility in response to changing food level
95  fatty acid oxidation, glucose oxidation and metabolic flexibility in soleus muscle cells from ABA-tr
96 red response to obesity reversal and reduced metabolic flexibility in the absence of CTRP11.
97  of nutrient transporters appears to mediate metabolic flexibility in this SCC model.
98 ndings reveal how microbial interactions and metabolic flexibility -including using alternative energ
99                        Genomic traits reveal metabolic flexibility, including mixotrophic nitrogen ac
100 sal fatty acid oxidation, maintained glucose metabolic flexibility, increased nonoxidative glucose di
101                                    Together, metabolic flexibility, increased reliance on mitochondri
102 performance and glucoregulation, and greater metabolic flexibility independent of diet composition.
103                                 This loss of metabolic flexibility, involving defects in adenosine, f
104 nergy homeostasis, and dysregulation of this metabolic flexibility is a dominant cause of several met
105                                              Metabolic flexibility is a hallmark of many cancers wher
106  does not alter adaptations to exercise when metabolic flexibility is already compromised.
107                           In cardiomyocytes, metabolic flexibility is crucial for the fulfillment of
108                                              Metabolic flexibility is defined as the ability to adapt
109 mulate physiological cardiac remodeling, and metabolic flexibility is important for maintaining mitoc
110                           Our data show that metabolic flexibility is important in the CNS in times o
111                 These findings indicate that metabolic flexibility is necessary to maintain DDR signa
112 aired systolic function, significant cardiac metabolic flexibility is retained, including the ability
113                                              Metabolic flexibility is the capacity of cells to alter
114                                              Metabolic flexibility is the key to the ecological succe
115 ics such as improved physical work capacity, metabolic flexibility, learning, and memory.
116                                         This metabolic flexibility likely explains the success of din
117 iac retinoic acid insufficiency and impaired metabolic flexibility linked to a compromised PDK4/PDH p
118 t-chain alkane metabolism suggests that such metabolic flexibility may be important in many environme
119                                     Retained metabolic flexibility may therefore be critical for subs
120          Genetic determinants limiting this "metabolic flexibility" may contribute to insulin resista
121 hanges in macronutrient composition of diet (metabolic flexibility) may be informative of individuals
122 on acceptors, which together with methanogen metabolic flexibility, may explain peat microbiome compo
123  in energy expenditure, glucose homeostasis, metabolic flexibility, mobility, and strength, excessive
124 cular dissection of its functions, providing metabolic flexibility needed for dietary adaptation.
125   Overall, our study uncovers a mechanism of metabolic flexibility occurring during ccRCC progression
126                 Insulin sensitivity (IS) and metabolic flexibility of 16 healthy, young male subjects
127 t adiponectin is a factor that increases the metabolic flexibility of adipose tissue, enhancing its a
128          This study unravelled an unexpected metabolic flexibility of aerobic methanotrophs, thereby
129     Decreasing glycolysis aims to combat the metabolic flexibility of both primary and secondary tumo
130          These results illustrate the marked metabolic flexibility of C. reinhardtii and contribute t
131 of HIF-1 or metabolic enzymes may impair the metabolic flexibility of cancer cells and make them more
132                                          The metabolic flexibility of Chlamydomonas offers a unique o
133 d culture GEO12CF provides insights into the metabolic flexibility of Dehalococcoides and could be us
134 olved in their metabolism are crucial to the metabolic flexibility of G. sulphuraria.
135 C-1alpha is involved in tumor growth and the metabolic flexibility of glioblastoma cells.
136 f polycations and vemurafenib diminishes the metabolic flexibility of melanoma cells, making them una
137               These results suggest that the metabolic flexibility of methanogenic archaea might be m
138                                              Metabolic flexibility of muscle tissue describes the ada
139                 Accordingly, G3PS safeguards metabolic flexibility of neurons to cope with energy dem
140                     Our findings support the metabolic flexibility of photorespiration and may help t
141 res and the protein complement highlight the metabolic flexibility of Picochlorum SE3 that encodes ge
142                                              Metabolic flexibility of skeletal muscle, that is, the p
143                              To evaluate the metabolic flexibility of syntrophic Desulfovibrio to ada
144 elative to fatty acids, thereby limiting the metabolic flexibility of the heart that is critically in
145   Relieving this inhibition can increase the metabolic flexibility of the hyperthyroid heart and redu
146 f the MTP family in Leishmania increased the metabolic flexibility of these protists and contributed
147  reservoir for tumour cells highlighting the metabolic flexibility of this cancer.
148 during a 6-wk period had a neutral effect on metabolic flexibility or postprandial glucose metabolism
149 ate, intramuscular triglyceride content, and metabolic flexibility (P = 0.016-0.048; n = 178).
150 hought to be one of the main contributors to metabolic flexibility-promoting mitochondrial energy pro
151 in ATP levels; however, beta cells lack this metabolic flexibility, resulting in a nitric oxide-depen
152 nglycosylatable SIRT1 in the liver abrogated metabolic flexibility, resulting in systemic insulin res
153                                              Metabolic flexibility seems to be reduced as a result of
154 s and laboratory experiments revealed a high metabolic flexibility, suggesting a considerable capacit
155 y contribute to the dynamic, tissue-specific metabolic flexibility that enables growth and survival i
156 n a persistent adult phenotype with improved metabolic flexibility that prevents DIO.
157 compared to controls and displayed a loss of metabolic flexibility that was not observed in fibroblas
158 glucose oxidation and is closely linked with metabolic flexibility, the importance of muscle PDH duri
159                                  An impaired metabolic flexibility to acute HFOF can identify individ
160  demonstrate that the diabetic heart retains metabolic flexibility to adapt to hypoxia, but is hinder
161 In conclusion, type 2 diabetic hearts retain metabolic flexibility to adapt to hypoxia, with normal H
162                           Some cells exhibit metabolic flexibility to circumvent mutations or aberran
163    We integrate macronutrient regulation and metabolic flexibility to elucidate how wild orangutans (
164                                              Metabolic flexibility to glucose (change in respiratory
165                       Therefore, we compared metabolic flexibility to glucose adjusted for glucose di
166                Additionally, the increase in metabolic flexibility to glucose after weight loss was a
167                                 The impaired metabolic flexibility to glucose observed in type 2 diab
168                          Many algae have the metabolic flexibility to grow photoautotrophically, hete
169                                        A low metabolic flexibility to lipid (MetF-lip) in skeletal mu
170 llular compartments provides plants with the metabolic flexibility to maintain physiological levels o
171 nitiating cells display stress tolerance and metabolic flexibility to survive in a harsh environment
172 using different nutrient sources, cells gain metabolic flexibility to survive periods of starvation.
173 ility of sleep/wake states and providing the metabolic flexibility to transition between states.
174                                              Metabolic flexibility was defined as the change in 24-h
175                                              Metabolic flexibility was measured in young sedentary me
176                                     In vivo, metabolic flexibility was positively correlated with IS
177                                              Metabolic flexibility was studied by determining the res
178 its on and evolutionary consequences of this metabolic flexibility, we developed a coarse-grained mat
179  connection between phenotypic switching and metabolic flexibility, where metabolic specialization of
180 et-induced obesity disrupts cardiac "diurnal metabolic flexibility", which is normalized by time-of-d
181 rtant regulator of HIF-driven glycolysis and metabolic flexibility, which influences the development
182 g had no effect on weight gain but increased metabolic flexibility while reducing body fat and liver
183 hat high levels of physical activity predict metabolic flexibility, while physical inactivity and sed
184 of plasma glucose and insulin, and a loss of metabolic flexibility with decreased lipid oxidation.
185 s are equipped with a somewhat unappreciated metabolic flexibility with important implications for th
186  eliminating glucotoxicity, which reinstates metabolic flexibility with restored preprandial lipid ox
187             The aged heart exhibits impaired metabolic flexibility, with a decreased capacity to oxid
188                    Our results highlight the metabolic flexibility within the isoflavonoid pathway, s
189      At the same time, a great potential for metabolic flexibility within this group is uncovered, wi
190 ities in high Candida samples display higher metabolic flexibility yet lower contributional diversity

 
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