ライフサイエンスコーパス: metabolomic analysis

1 had not previously been subject to detailed metabolomic analysis.

2 I-MS) is a versatile and robust platform for metabolomic analysis.

3 mined using an untargeted global and focused metabolomic analysis.

4 rved after 2.1-fold dilution of CL1-0 before metabolomic analysis.

5 ites and will earn a place in the toolbox of metabolomic analysis.

6 onses to dehydration using untargeted global metabolomic analysis.

7 systematic bias and ensuring the quality of metabolomic analysis.

8 ion steps before applying enzymatic assay or metabolomic analysis.

9 fication, and supernatants were prepared for metabolomic analysis.

10 -MS) was evaluated for its utility in global metabolomics analysis.

11 tential to largely improve the throughput of metabolomics analysis.

12 for diagnostic tests and, increasingly, for metabolomics analysis.

13 mass spectrometry (LC-Q-TOF-MS)-based global metabolomics analysis.

14 ation of targeted metabolites in large-scale metabolomics analysis.

15 ts and have great but untapped potential for metabolomics analysis.

16 rm, offering better sensitivity for targeted metabolomics analysis.

17 GFP-marked cells from Arabidopsis roots for metabolomics analysis.

18 ron in an ion-dependent molecular networking metabolomics analysis.

19 xity of chemical fingerprints in multi-class metabolomics analysis.

20 h we present biomarkers identified by global metabolomics analysis.

21 knockdowns in a combined transcriptomics and metabolomics analysis.

22 along with muscle samples for histology and metabolomics analysis.

23 total of 886 molecules were measured in our metabolomics analysis.

24 hromatography/mass spectrometry were used in metabolomics analysis.

25 et metabolites using large-scale comparative metabolomics analysis across a database of 10,498 extrac

26 small molecules detected by the nontargeted metabolomic analysis after choline depletion.

27 mated platform for quantitative 1D NMR-based metabolomics analysis allowing a wide range of applicati

28 Targeted metabolomic analysis also provided the first evidence th

29 Consistent with transcriptomic analysis, metabolomic analysis also revealed the accumulation of m

30 We developed Statistical Metabolomics Analysis-An R Tool (SMART), which can analy

31 UHPLC-QToF analysis was used for untargeted metabolomic analysis and 192 metabolites were annotated.

32 Metabolomic analysis and biochemical studies indicated t

33 Metabolomic analysis and cell-based assays show that los

34 By using comparative metabolomic analysis and enzyme-immunoassay, our results

35 Metabolomic analysis and microfluidic experiments furthe

36 measurement of metabolic rates, followed by metabolomic analysis and subcellular fractionation.

37 Unbiased large-scale metabolomic analysis and transcriptome-wide mRNA express

38 Here we describe a software package, Metabolomic Analysis and Visualization ENgine (MAVEN), d

39 Finally, metabolomics analysis and adenosine triphosphate product

40 Untargeted metabolomics analysis and glycogen kinetics suggest that

41 veloped an in-depth workflow combining urine metabolomics analysis and machine learning bioinformatic

42 ting patients, and providing DNA sequencing, metabolomic analysis, and functional studies in model or

43 Here we develop a comparative in vivo metabolomic analysis, and unexpectedly identify widely c

44 rehensive insight, but many methods used for metabolomics analysis are too complex and time-consuming

45 g genomic with transcriptomic, proteomic and metabolomic analysis, as well as clinical events could,

46 A metabolomics analysis based on LC-HRMS was carried out o

47 te-spinal neuron co-cultures, we carried out metabolomic analysis by (1)H NMR spectroscopy of media f

48 First, the untargeted metabolomic analysis by high-resolution mass spectrometr

49 ces in average daily gain (ADG), rumen fluid metabolomic analysis by LC-MS and multivariate/univariat

50 Metabolomic analysis by liquid chromatography-high-resol

51 m early to advanced clinical staging through metabolomic analysis by mass spectrometry in plasma and

52 FT-Raman microspectroscopy and subjected to metabolomics analysis by ultra-HPLC (uHPLC), coupled to

53 of each 4-wk period in the fasting state for metabolomics analysis by using liquid chromatography-tan

54 sion, ADEMA advances the state-of-the-art in metabolomics analysis, by providing accurate and interpr

55 spective study aimed to assess whether urine metabolomic analysis can be used to identify children wi

56 Metabolomic analysis confirmed no change in cellular met

57 Importantly, metabolomic analysis confirmed that Abcb11 KO mice have

58 Meanwhile, untargeted metabolomic analysis confirmed the representativeness of

59 Untargeted metabolomic analysis defined 29 biochemicals significant

60 An untargeted metabolomic analysis demonstrated distinct seasonal vari

61 Metabolomic analysis demonstrated that BSH inhibitor tre

62 Metabolomic analysis demonstrated that in response to st

63 Metabolomic analysis demonstrated that lactate levels in

64 Metabolomic analysis demonstrated that MUC1-mediated CDA

65 Metabolomic analysis demonstrated that mutant plants und

66 Metabolomics analysis demonstrated accumulation of gluta

67 Metabolomic analysis demonstrates that BCH070 likely tar

68 Based on data from microbial sequencing and metabolomics analysis demonstrating that young fecal tra

69 Metabolomic analysis detected biomarkers associated with

70 thymidylate synthase was also repressed and metabolomic analysis detected widespread alteration of h

71 Consequently, metabolomics analysis during miR-127-3p-induced cell cyc

72 athways, this biofluid is ideally suited for metabolomic analysis, especially involving diseases of t

73 bal cellular metabolism, providing the first metabolomic analysis for a member of the poxvirus family

74 tology, and pairs these data with untargeted metabolomics analysis for de novo bioactive compound dis

75 Metabolomic analysis found an accumulation of bile acids

76 In this study, comparative metabolomic analysis found that the endogenous levels of

77 arities based on Nutrition Facts panels, our metabolomics analysis found that metabolite abundances b

78 To address the challenge of metabolomic analysis from MS data, a web-based applicati

79 Combined gene expression and metabolomics analysis have shown differential expression

80 Metabolomic analysis highlighted key coffee-related meta

81 Proteomic and metabolomic analysis highlighted roles for LIN28 in main

82 One weakness of untargeted metabolomic analysis, however, is the difficulty of iden

83 Metabolomic analysis identified 39 secreted solutes with

84 Metabolomic analysis identified 712 biochemicals, and 69

85 Finally, unbiased metabolomic analysis identified four metabolites that we

86 Metabolomic analysis identified increased cresol levels

87 Metabolomic analysis identified two hydroxylated interme

88 Gas chromatography-mass spectrometry metabolomics analysis identified differences between ROC

89 Nuclear magnetic resonance-based metabolomics analysis identified key metabolic pathway d

90 Differential metabolomics analysis identified significant changes in

91 Here metabolomic analysis in combination with ex vivo insect

92 for high-throughput targeted UHPLC-ESI-MS/MS metabolomic analysis in large-scale clinical and epidemi

93 d a combined functional, transcriptomic, and metabolomic analysis in mice with inducible conditional

94 ing of spatially resolved transcriptomic and metabolomic analysis in patients' tissues revealed stron

95 A blood metabolomics analysis in a cohort of adolescents with or

96 r findings represent the first comprehensive metabolomics analysis in HGSOC and propose a new set of

97 on the blood metabolome (non-targeted LC-MS metabolomics analysis) in 96 sAUD patients hospitalized

98 A global unbiased microbiome and metabolomics analysis independently confirmed that glyce

99 Metabolomic analysis indicated increased fecal mevalonat

100 Finally, metabolomic analysis indicated that HF impaired a refeed

101 The metabolomic analysis indicated that l-lysine, mellein, a

102 able and did not have an apparent phenotype, metabolomic analysis indicated that they had metabolic s

103 nscarbamylase, and dihydroorotase (CAD), and metabolomic analysis indicates that cyclin D1 depletion

104 A major bottleneck of mass spectrometric metabolomic analysis is still the rapid detection and an

105 A major challenge for metabolomic analysis is to obtain an unambiguous identif

106 These data show that serum metabolomics analysis is a more accurate proxy for tissu

107 Therefore, (1)H NMR-based metabolomics analysis is focused on targeted studies rel

108 host immune function against pathogens, and metabolomic analysis may help understand the characteris

109 ibited SHMT2 ~19-fold greater than AGF347 By metabolomics analysis, mFPGS stimulated the C1 flux from

110 Serum samples were collected for global metabolomic analysis (n = 8/group/sex).

111 We performed a metabolomic analysis of 1,282 male smoker participants b

112 In the metabolomic analysis of 36 samples from different catego

113 Quantitative metabolomic analysis of a panel of 26 bioactive lipids d

114 Here, we describe a comprehensive metabolomic analysis of a systemic bacterial infection u

115 Metabolomic analysis of adipose tissue indicated that eN

116 mic reflex tests and targeted fasting plasma metabolomic analysis of amino acids and TCA cycle interm

117 functionalities is demonstrated through the metabolomic analysis of bacterial stress response and th

118 ctrospray ionization mass spectrometry-based metabolomic analysis of CASE and uncolored avocado seed

119 ying mechanism, we performed a proteomic and metabolomic analysis of cultured vascular smooth muscle

120 Furthermore, metabolomic analysis of dAhcyL1-deficient flies revealed

121 Chemical and metabolomic analysis of dauer-inducing pheromone has ide

122 Unbiased and targeted metabolomic analysis of fasted mice with a conditional k

123 In a previous study, we performed a metabolomic analysis of gingival crevicular fluid collec

124 This platform was applied to an untargeted metabolomic analysis of head and neck cancer cells and s

125 Integrated transcriptomic and metabolomic analysis of human kidneys showed that kidney

126 A method for performing untargeted metabolomic analysis of human serum has been developed b

127 This is the first report showing that metabolomic analysis of human urine samples could become

128 ngle-probe MS, capable of real-time, in situ metabolomic analysis of individual living cells.

129 Metabolomic analysis of KDM3B knockout showed a decrease

130 Large scale metabolomic analysis of liver tissue confirms that both

131 However, the proteomic and metabolomic analysis of low-volume samples remains chall

132 Metabolomic analysis of maize revealed that PGPB inocula

133 d mass spectrometry to perform an untargeted metabolomic analysis of metabolite extracts from Plasmod

134 Furthermore, metabolomic analysis of murine fecal water detected sign

135 FT-ICR-MS metabolomic analysis of mutant cells showed changes in l

136 Using metabolomic analysis of mutants, we demonstrate that Ara

137 Here, we present a method based on an NMR-metabolomic analysis of organic extracts for a geographi

138 Metabolomic analysis of P. falciparum parasites in vitro

139 A metabolomic analysis of PGDH mutant and overexpressing p

140 rganic compounds and performed an untargeted metabolomic analysis of plasma collected at multiple tim

141 ur in vitro results, we performed a targeted metabolomic analysis of plasma samples from TN HBOC pati

142 All subjects underwent nontargeted metabolomic analysis of plasma samples using gas and liq

143 We carried out untargeted metabolomic analysis of sera collected from female BALB/

144 Here, we performed (1)H-NMR based metabolomic analysis of serum and whole-blood from lutei

145 s spectrometry (nanoLC-MS) for high-coverage metabolomic analysis of small numbers of cells (i.e., </

146 re directions for this area of study include metabolomic analysis of species- and condition-dependent

147 eport nuclear magnetic resonance (NMR) based metabolomic analysis of surgically resected tumors from

148 technical limitations have precluded a full metabolomic analysis of SV content.

149 of endogenous metabolites present in sweat, metabolomic analysis of sweat with high coverage is diff

150 Metabolomic analysis of the blood by tandem mass spectro

151 HB17), whose activity we identified based on metabolomic analysis of the corresponding knockout strai

152 Untargeted high-resolution LC-MS metabolomic analysis of the extracted filtrates and myce

153 LC-UV/MS-based metabolomic analysis of the Hawaiian endophytic fungus P

154 Metabolomic analysis of the liver and plasma shows a pos

155 Subsequent metabolomic analysis of the spent medium for growth on C

156 ointestinal and urinary tracts, along with a metabolomic analysis of the urinary metabolome, from sub

157 Metabolomic analysis of the wines using NMR did not find

158 After mass spectrometry-based metabolomic analysis of these extracts, we "credential"

159 zebrafish liver (ZFL) cell-culture based NMR metabolomic analysis of these split stream samples.

160 DI-MSI) enables detailed, spatially resolved metabolomic analysis of tissue samples.

161 Metabolomic analysis of urinary metabolites revealed tim

162 Mass spectrometry-based metabolomic analysis of urine and tissues from wild-type

163 However, the comprehensive metabolomic analysis of urine has been somewhat less stu

164 The method was applied to the comparative metabolomic analysis of urine samples from healthy contr

165 would be measurable in biofluids and that a metabolomic analysis of urine would provide insight into

166 A metabolomic analysis of volatile organic compounds (VOCs

167 Mechanistically, comparative metabolomic analysis of zebrafish with/without B-cell ab

168 Metabolomics analysis of ACC-deficient liver identifies

169 Global metabolomics analysis of Ahr(-/-) mice revealed the role

170 Uniform metabolomics analysis of all three "matrices" was accomp

171 Untargeted metabolomics analysis of an S. cerevisiae deletion mutan

172 Metabolomics analysis of avian plasma showed significant

173 -MS) is a standard method for proteomics and metabolomics analysis of biological samples.

174 Lastly, metabolomics analysis of bone marrow-derived mast cells

175 By combining metabolomics analysis of both plant extracts and in vitr

176 Steady-state metabolomics analysis of brain and liver from Mpc1 hypom

177 A metabolomics analysis of cecal contents from GV-971-trea

178 In this study, we performed metabolomics analysis of cerebrospinal fluid (CSF) from

179 A metabolomics analysis of cultured human choroidal endoth

180 Metabolomics analysis of fasting plasma from obese, Zuck

181 In this study, untargeted metabolomics analysis of fasting plasma from stable card

182 romatography-mass spectrometry (LC-MS)-based metabolomics analysis of human biospecimens has become a

183 Untargeted metabolomics analysis of in vivo (1)H-MRS spectra discri

184 In particular, spatial metabolomics analysis of kidney biopsy samples could hav

185 Metabolomics analysis of patient colon tumors (n = 197)

186 Targeted metabolomics analysis of plasma of mice revealed an incr

187 As a result of the metabolomics analysis of rumen fluid, 33 metabolites dif

188 We performed a cross-sectional metabolomics analysis of samples collected from overweig

189 In this study, we conduct a metabolomics analysis of six modulatory bacterial specie

190 s and subjected to metabolic phenotyping and metabolomics analysis of skeletal muscle.

191 This study describes a metabolomics analysis of the LPS-stimulated bMECs to pro

192 In this study, untargeted metabolomics analysis of triple-negative breast cancer (

193 Metabolomics analysis of TT8 loss-of-function and induci

194 n GC x GC-TOFMS against that of GC-TOFMS for metabolomics analysis of two different plasma matrices,

195 chemical networks, we conducted a replicated metabolomic analysis on 210 lines of an Arabidopsis popu

196 Here we used global metabolomic analysis on bile from specific-pathogen-free

197 Here we present a comparative circadian metabolomic analysis on serum and liver in mice under hi

198 ent these studies, we conducted a replicated metabolomics analysis on a japonica (Lemont) by indica (

199 Transcriptomics and metabolomics analysis on enzymatic discoloration after 5

200 mics in individual diagnosis, we conducted a metabolomics analysis on plasma samples collected from 8

201 Metabolomic analysis, on the other hand, revealed an int

202 anscriptional, and two-dimensional NMR-based metabolomic analysis performed using multiple inbred mou

203 describe mzMatch-ISO, a new extension to the metabolomics analysis pipeline mzMatch.R.

204 DBS-based metabolomics analysis provides a powerful tool for inves

205 ts biotransformation products as part of the metabolomics analysis provides an opportunity to simulta

206 In addition, metabolomic analysis revealed alterations in amino acid

207 The metabolomic analysis revealed changes in endogenous meta

208 susceptible animals in serum and brain; and metabolomic analysis revealed dysfunction of purine meta

209 Detailed metabolomic analysis revealed elevated nicotinamide meta

210 Metabolomic analysis revealed increased levels of branch

211 Overall, the combination of biochemical and metabolomic analysis revealed NAT is a novel metabolite

212 Comprehensive necropsy, histopathology, and metabolomic analysis revealed no toxicity of the cells.

213 Our metabolomic analysis revealed novel biomarkers associate

214 This metabolomic analysis revealed potential novel biomarkers

215 Metabolomic analysis revealed presence of multiple antid

216 Liver metabolomic analysis revealed significant changes in dia

217 Metabolomic analysis revealed significant sex-, diet-, a

218 Metabolomic analysis revealed significantly higher conce

219 In parallel, metabolomic analysis revealed stark differences in plasm

220 Metabolomic analysis revealed that 5-aminolevulinic acid

221 (13)C metabolomic analysis revealed that anaerobically grown S

222 Metabolomic analysis revealed that exposure to AS-HK014,

223 Metabolomic analysis revealed that metabolites in the gl

224 Metabolomic analysis revealed that ozone exposure marked

225 Metabolomic analysis revealed that pyrimidine biosynthet

226 (1)H NMR spectroscopy metabolomic analysis revealed that systemic metabolic al

227 nsive untargeted and stable isotope-assisted metabolomic analysis revealed that the bacteria utilize

228 LC-MS/MS-based metabolomics analysis revealed 15 key metabolites, with

229 Metabolomics analysis revealed a defect in the catabolis

230 Moreover, non-targeted metabolomics analysis revealed a group of chlorinated me

231 Further, metabolomics analysis revealed a S. parasanguinis-driven

232 sing liquid chromatography-mass spectrometry metabolomics analysis revealed changes (p-value </= 0.05

233 Intracellular metabolomics analysis revealed decreasing levels of redo

234 LC/MS/MS metabolomics analysis revealed that AICAr increases orot

235 However, metabolomics analysis revealed that both doses of CeO(2)

236 Metabolomics analysis revealed that rTM treatment allevi

237 Eventually, GC-MS based metabolomics analysis revealed the higher activity of pl

238 Metabolomic analysis reveals reduced methionine content

239 Metabolomic analysis reveals that dietary uptake of glut

240 Metabolomic analysis reveals that long lags result from

241 sferase like 14) by Nestin-Cre together with metabolomic analysis reveals that Mettl14 knockout-induc

242 Metabolomics analysis reveals global differences in meta

243 Metabolomics analysis reveals increased ATP production a

244 An integrated transcriptomics and metabolomics analysis reveals that ADSL activates the on

245 Integrated transcriptional and metabolomics analysis reveals that Yap transcribes Myc a

246 Prior to LC-ESI-qToF-MS-driven metabolomic analysis, samples were subjected to differen

247 Metabolomic analysis showed a 2.2 times increase in acet

248 Finally, our metabolomic analysis showed a significant reduction in t

249 Mass spectrometry-based metabolomic analysis showed Hh inhibition induced signif

250 Metabolomic analysis showed large increases in lipid pro

251 A metabolomic analysis showed that the up-regulation of un

252 red palmitate-linked oxygen consumption, and metabolomics analysis showed reduced indices of FAO.

253 Metabolomics analysis showed that genotypic and dietary

254 Metabolomics analysis showed that the treatment with CA

255 Chemical space studied through metabolomic analysis, showed increased presence of nitro

256 Furthermore, metabolomics analysis suggested STP7 is a sugar starvati

257 Metabolomic analysis thereby revealed cryptic changes to

258 We used metabolomic analysis to examine cellular metabolism in l

259 We used high-throughput metabolomic analysis to identify several lipids in which

260 , transcriptional profiling, epigenetic, and metabolomic analysis to offer a means to develop both a

261 geted and targeted applications ranging from metabolomic analysis to preparative purifications.

262 Here, we used targeted metabolomic analysis to reveal dose-dependent changes in

263 "Radiation metabolomics," the application of metabolomic analysis to the field of radiobiology, promi

264 database, for one-dimensional (1D) NMR-based metabolomics analysis to address these challenges.

265 we used an unbiased mass spectrometry-based metabolomics analysis to define differences in metabolit

266 Here, we used an untargeted metabolomics analysis to define system-level alterations

267 ying combined grade-dependent proteomics and metabolomics analysis to determine how metabolic reprogr

268 renal cortex, and medulla samples underwent metabolomic analysis using 1-dimension and 2-dimension n

269 withdraw approximately 3 pL of cytoplasm for metabolomic analysis using CE-MS.

270 om adult and baby pandas for high throughput metabolomics analysis using gas chromatography-mass spec

271 liver, and lung were analyzed by nontargeted metabolomics analysis using gas chromatography/mass spec

272 Blood samples were obtained for untargeted metabolomics analysis using UPLC-MS/MS.

273 n this article, we describe a multi-platform metabolomic analysis, using NMR, mass spectrometry and H

274 sake of comparison, a parallel 1H NMR-based metabolomic analysis was also conducted on the unfiltere

275 Subsequent metabolomic analysis was capable of constructing a princ

276 magnetic resonance (NMR) spectroscopy-based metabolomic analysis was performed in 24-hour urine samp

277 Metabolomic analysis was performed on methanol extracts

278 ers for therapeutics development, untargeted metabolomic analysis was performed on primary human airw

279 A pre-planned targeted metabolomic analysis was performend using Nuclear Resona

280 magnetic resonance (NMR) spectroscopy-based metabolomic analysis was used to identify metabolites in

281 In this study, untargeted metabolomics analysis was employed to characterize the b

282 An untargeted UHPLC-Q-Orbitrap metabolomics analysis was performed and provided valuabl

283 An untargeted LC-MS-based metabolomics analysis was performed on a set of 30 wines

284 LC-MS-based targeted metabolomics analysis was performed on fasting plasma sa

285 ed glomerular filtration rate), and a plasma metabolomics analysis was performed using baseline metab

286 Through targeted metabolomics analysis we identified the tyrosine derivat

287 After performing targeted metabolomic analysis, we characterize the metabolites co

288 Using integrated physiological and metabolomic analysis, we determined that B12 deficiency

289 Through metabolomic analysis, we have identified links between a

290 In addition to the overall metabolomics analysis, we also analyzed individual metab

291 By metabolomics analysis, we found an increase in long-chai

292 In metabolomics analysis, we found reduced levels of a bran

293 n HeLa cells with high-resolution untargeted metabolomics analysis, we have developed a new platform,

294 proach and transcriptome analysis as well as metabolomics analysis, we reveal that CsdA and RsdA syne

295 Electron microscopy and metabolomic analysis were performed on mouse RVs.

296 Current and potential applications of metabolomics analysis will be addressed, focusing on pro

297 Metabolomic analysis with bioinformatics is used to unde

298 Fruit metabolomic analysis with HRMAS-NMR indicated significan

299 Comprehensive metabolomics analysis with liquid chromatography-mass sp

300 ', unifying 'omics' (lipidomics, proteomics, metabolomics) analysis with native mass spectrometry to