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1 gene expression, genotyping, proteomics and metabonomics.
2 h particular application in metabolomics and metabonomics.
3 ion of international reporting standards for metabonomics.
4 ne of the central approaches in the field of metabonomics.
5 bility PCR, 16S rRNA sequencing and 1(H) NMR metabonomics.
6 y of similar but not identical proteomic and metabonomic alterations in the chronic PCP rat model and
7 study presents temporal comparative (1)H NMR metabonomic analyses of filamentous phage pf1 infection
10 for high-throughput targeted UPLC-ESI-MS/MS metabonomic analysis in clinical and epidemiological env
11 the NMR spectrum of honey and its classical metabonomic analysis is completely dominated by a very f
12 authors recently proposed an approach to the metabonomic analysis of biofluid mixtures based on the u
13 ethod that is well suited to high-throughput metabonomic analysis of complex mixtures such as urine c
18 ed to analyse changes in the microbiome, and metabonomic analysis was performed using proton nuclear
23 ial will also provide opportunity to conduct metabonomic and gut microbiome studies as explorative an
27 including metabolic profiling (metabolomics/metabonomics) and lipidomics, are making a significant i
30 es in biofluid composition than the standard metabonomic approach using complete 1D proton NMR spectr
32 rofiles can be selectively amplified using a metabonomics approach based on the different NMR spectra
33 oney samples, a comparison of this classical metabonomics approach to one based on the use of the sel
34 n alternative and conceptually new 'pharmaco-metabonomic' approach to personalizing drug treatment, w
40 arized CCA and correlation analyses of urine metabonomics data and 16S rRNA gene sequencing data to i
41 ciations between specific longitudinal urine metabonomics data and microbiome data in a diet-induced
43 PLS allowed us to explore longitudinal urine metabonomics data in relation to the dietary groups, as
46 ne-expression profiling, metaproteomics, and metabonomics, differences in microbial composition and f
47 y should facilitate translation of NMR-based metabonomics discovery of human disease biomarkers to cl
50 tegy combining pharmacokinetics, toxicology, metabonomics, genomics, and metagenomics to elucidate an
55 nd cotton ball brands be characterized using metabonomics methodologies prior to initiating a metabon
56 nimals and show that it is possible to apply metabonomics methodology to this important class of biof
57 sis of metabolic data and shows the value of metabonomic methods in the investigation of physiologica
62 spectra is an important tool in large-scale metabonomic or metabolomic studies, where hundreds or ev
63 vatives, their impact on the composition and metabonomic profile of a defined community of human gut
66 used functional genomic approaches including metabonomic profiling and gene expression analyses to id
67 aphy-mass spectrometry (LC-MS) proteomic and metabonomic profiling approaches on prefrontal cortex (P
68 and proton nuclear magnetic resonance-based metabonomic profiling of the rat frontal cortex after ch
72 ating existing postgenomic data with current metabonomic results in P. aeruginosa biofilms research.
73 romatography/mass spectrometry (LC/MS) based metabonomics screening of urine has great potential for
74 onal genomic, transcriptional, proteomic and metabonomic signatures to characterize drug mechanisms a
76 fication of potential biomarker molecules in metabonomic studies based on NMR spectroscopic data.
81 omplicates biomarker information recovery in metabonomic studies when using multivariate statistical
82 s large sample cohorts common in metabolomic/metabonomic studies, we have developed a prealignment pr
92 en applied to 1H NMR spectra of urine from a metabonomic study of a model of insulin resistance based
95 a set of metabolites (e.g. biomarkers from a metabonomic study) and plots the connectivity between me
96 bonomics methodologies prior to initiating a metabonomics study to ensure that contaminant profiles a
99 se of nuclear magnetic resonance (NMR)-based metabonomics to search for human disease biomarkers is b
103 ectra or mixtures of compounds, as in chiral metabonomics, where severe overlapping exists in proton