ライフサイエンスコーパス: metal center

1 vity (multiple chains of block copolymer per metal center).

2 s with different metal centers, or lacking a metal center.

3 in the immediate vicinity of the transition metal center.

4 uences resulting in product release from the metal center.

5 itude of the potential is independent of the metal center.

6 binding of the counteranion to the cationic metal center.

7 n delocalized in the ligands surrounding the metal center.

8 tructure of a BMC shell protein containing a metal center.

9 te reductive elimination from a destabilized metal center.

10 judicious choice of N,O-chelating ligand and metal center.

11 the spin is localized almost entirely on one metal center.

12 hanol), has been prepared with indium as the metal center.

13 ectron transfer at a well-defined transition metal center.

14 ical energy and funnel it to the luminescent metal center.

15 from a difluorocarbene insertion on a cobalt metal center.

16 and zebrafish, demonstrating the role of the metal center.

17 nstead of an electronic interaction with the metal center.

18 t turnover-limiting hydrogen transfer to the metal center.

19 trol the catalytic activity of the adjoining metal center.

20 t now from the porphyrin ring instead of the metal center.

21 ate moiety, linker, phosphane coligands, and metal center.

22 t changing the oxidation state of the apical metal center.

23 agostic coordination of a Me-Si group to the metal center.

24 vinylallene fragment is pushed away from the metal center.

25 ns because of a loss or decomposition of the metal center.

26 xperimental marker for the spin state of the metal center.

27 used for the stabilization of the palladium metal center.

28 ive addition of the C(8)-halogen bond to the metal center.

29 d reformation of nacnac ligands bound to the metal center.

30 ichiometrically oxidized by one electron per metal center.

31 for inhibitors that compete with 2OG at the metal center.

32 its gel-sol transition upon oxidation of the metal center.

33 rtion of CO2 into a C-H bond remote from the metal center.

34 the two phosphonic groups now bonded to the metal center.

35 es for the ligands directly coordinating the metal center.

36 oxidation state change of -2 at a transition-metal center.

37 ve olefin activation via coordination to the metal center.

38 y binding substrates in proximity to a bound metal center.

39 ledge, of P.A. anion bound to a redox-active metal center.

40 molecule proceeds without first reducing the metal center.

41 ihydrogen is bound to a subvalent transition metal center.

42 om the electronic delocalization through the metal centers.

43 ssfully coordinate to both Pd(II) and Ru(II) metal centers.

44 within a distribution of inactive spectator metal centers.

45 rdinate the cyclic framework to a variety of metal centers.

46 nd the functional Lewis acid strength of the metal centers.

47 gen and silicon-hydrogen bonds to transition metal centers.

48 licated in a range of catalytic processes at metal centers.

49 obe the early stages of hydride formation at metal centers.

50 t includes a cyclooctyne ligand bridging two metal centers.

51 M(II)4L6 assembly with facially coordinated metal centers.

52 involving hemilabile ligands and transition metal centers.

53 lanar molecules, a typical geometry for d(8) metal centers.

54 anes and into molecules containing up to 200 metal centers.

55 a partially deprotonated bridge between two metal centers.

56 ic agents through PET utilizing redox-active metal centers.

57 ut involving higher oxidation states for the metal centers.

58 e in the underlying oxidation numbers of the metal centers.

59 Oslo) with coordinatively unsaturated active metal centers.

60 c frameworks and other MOMs with unsaturated metal centers.

61 orbital interactions between low-coordinate metal centers.

62 tions by one-electron redox processes at two metal centers.

63 tive to that of the octahedrally coordinated metal centers.

64 4H) bridge isovalent (most probably Fe(III)) metal centers.

65 hese electrons are supplied from one or more metal centers.

66 e linker (H(4)TPBD) and Zn(II) and Cd(II) as metal centers.

67 rmations that are traditionally described as metal-centered, 2-electron Cu(I)/Cu(III) redox processes

68 retching vibrational wavepacket on a triplet metal-centered ((3)MC) excited state surface.

69 etallic compounds were designed to feature a metal center, a 2-pyridinecarbothioamide (PCA), and a hy

70 llows observation of the redox state of both metal centers, a direct read-out of electron transfer, d

71 ridine substrate (both free and bound to the metal center), absorptive signals are observed from hype

72 can be described as interactions between the metal center (active site) and the surface functionality

73 the helical twist of the PyNHC ligands, the metal center adopts either a Lambda or Delta absolute co

74 angement of the nonchiral ligands around the metal center affords a chiral structure with two geometr

75 cts as a directing group by chelating to the metal center, affords a potential route for the transfor

76 hich suggest that the dramatically displaced metal center allowing a promotion e(g)(d(pai)) -> b(1g)(

77 stematic variation of the BPI ligand and the metal center along with mechanistic investigations of th

78 l contraction in all bond lengths around the metal centers, along with diagnostic shifts in the spect

79 The role of cooperativity between a reduced metal center and a Lewis acid center in small-molecule a

80 action of the sulfur-based orbitals with the metal center and are demonstrated to be useful reporters

81 though such species bind only weakly to the metal center and are themselves then easily displaced; t

82 d, which lacks pi-donor stabilization of the metal center and consequently has a very small HOMO-LUMO

83 ive assignment of the stereochemistry at the metal center and reveal secondary coordination sphere in

84 Thus, subtle changes in the porphyrin metal center and ring conformation may influence the ago

85 es the terminal PN O atom (farthest from the metal center and ring core), effecting O-O cleavage, giv

86 ch a combination of the steric pocket of the metal center and substrate size determines the reaction

87 e proximity of the chiral information to the metal center and the ability to switch between S and O c

88 preserve the mixed-valence character of this metal center and the electron transfer functionality.

89 include an interaction between the platinum metal center and the surface oxygen atoms.

90 lish the configuration of the resting enzyme metal center and, importantly, reveal the formation of a

91 haracterized by specific redox states of the metal centers and a distinct protein conformation.

92 location pathway consisting of two binuclear metal centers and an interim zinc-binding site.

93 oupling, which can be tuned by designing the metal centers and coordination environments of catalysts

94 = tert-butyl), which feature low-coordinate metal centers and direct metal-metal orbital overlap.

95 This results in more oxidized metal centers and ejected lithium ions are created under

96 ble chain transfer between active transition-metal centers and excess equivalents of inactive main-gr

97 ous chains of coordination bonds between the metal centers and ligands' functional groups create char

98 ygen also directly damages the low-potential metal centers and radical-based mechanisms that optimize

99 ared alpha-cationic arsines toward different metal centers and their reactivity in the presence of st

100 halide/pseudohalide anions are bound to the metal centers and thus stationary, the cations move free

101 cepting electrons to activate substrates and metal centers and to enable new reactivity with both ear

102 networks that have coordinatively saturated metal centers and two distinct types of micropores, one

103 d into defined 3D structures upon binding to metal centers and/or lanthanides.

104 involve changes of the oxidation state of a metal center, and it is particularly useful in complex c

105 sensitive to the electronic structure of the metal center, and the high-spin sensitivity, fast time r

106 I)4L6 assembly with meridionally coordinated metal centers, and a C3-symmetric self-included M(II)4L6

107 and concentration of products, reduction of metal centers, and chemical environments of the organic

108 catalyst benzyl groups expand the "cationic" metal center-anionic sulfated oxide surface distances, a

109 tly, reducing the coordination number of the metal centers appears to increase axial magnetic anisotr

110 er a distal (3-substituent furthest from the metal center) approach.

111 H(-) or Cl(-), bound to the lower coordinate metal center are supported through the hydrogen-bonding

112 Three of the metal centers are coordinated to our previously reported

113 d timescales and d(2) nature of the vanadium metal centers are inconsistent with a Peierls driving fo

114 es, isolated chemisorption sites on the CuPc metal centers are observed in STM images.

115 d functionalization at group 8-10 transition metal centers are reviewed.

116 t switches from a dinuclear to a mononuclear metal center as phosphates are eliminated from substrate

117 the structural and electronic demands of the metal center at different oxidation states accessed with

118 dox response of the bipyridine ligand and Ru metal center at negative potentials, as well as the inhi

119 tion is demonstrated for a single main group metal center at room temperature.

120 tly to the degree of electron density at the metal center because they occur with different turnover-

121 stage, the first coordination sphere of the metal center becomes seven coordinated.

122 (BbZIP) revealed an unprecedented binuclear metal center (BMC) within the transport pathway.

123 structures, metal-centered boron rings, and metal-centered boron drums.

124 ructures including half-sandwich structures, metal-centered boron rings, and metal-centered boron dru

125 erine revealed binding interactions near the metal center but did not identify a binding pocket for t

126 dway between the two spin states of a single metal center but no electrical charge.

127 for ligand exchange reactions not only at a metal center, but also at main group elements.

128 uggest that O2 activation occurs on a single metal center, by an oxidative addition on the quartet su

129 o mediate electron hopping between high-spin metal centers, by providing the first example of an Fe c

130 ngle-atom catalysts with full utilization of metal centers can bridge the gap between molecular and s

131 is a lack of model system for understanding metal-centered catalysis on the basal planes.

132 s, but biochemical measurements only suggest metal-centered catalytic electron transfer.

133 ation to the 2-acyl imidazole substrate, the metal-centered chirality is maintained throughout the ca

134 proteins, which illuminate the influence of metal-centered chirality on these interactions.

135 f the inhibited enzyme are consistent with a metal-centered cobalt radical ~6 angstroms away from the

136 hat provide the reactivity of the introduced metal center combined with specifically intended product

137 e characterize the impact of chloride on the metal center coordination and reactivity of the fatty ac

138 eneration metalloradical catalysts where the metal-centered d-radical is situated inside a cavity-lik

139 carbon nanospheres containing porphyrin-like metal centers (denoted as "PMCS") are successfully synth

140 The local geometry at the metal center depends on the metal ion employed, with Cu(

141 taining structures of intact redox states of metal centers derived from zero dose X-ray crystallograp

142 d, whereby the ligand environment around the metal center dictates the regiochemical outcome.

143 s the partial deconfinement of the monatomic metal centers driven by CO at precatalysis temperatures,

144 sights into unforeseen rearrangements of the metal center during catalysis.

145 ns and an interrogation into the fate of the metal center during this interesting transformation.

146 l porphyrin-based excitation, some involving metal centered electronic configuration changes that cou

147 the case of polymorphs), and their saturated metal centers eliminate open metal sites from dominating

148 plex according to MD simulation-in which the metal centers embed in the lipid head group region and t

149 This interplay of multiple metal centers enables introduction of an orthogonal alky

150 he high charge density retained by the M(2+) metal centers exposed within the M(2)(m-dobdc) structure

151 overall chirality results from a stereogenic metal center featuring either a Lambda or Delta absolute

152 moiety on the triple bond coordinated to the metal center followed by alkoxycarbonylation.

153 e of the solvent-derived ligand, priming the metal center for reduction and subsequent O2 binding.

154 essential ligands for the catalytic Mn4CaO5 metal center for water oxidation by PSII.

155 ectrons: the electronic configuration of the metal center has to provide occupied or empty orbitals t

156 studies suggest that gas binding to the iron metal center heme may drive alterations in REV-ERB activ

157 preciate that COX relies on its redox-active metal centers (heme a and a3, CuA and CuB) to reduce oxy

158 etaine moiety cooperates with a Lewis acidic metal center (here Cu(II)) within a chiral catalyst fram

159 complexes with unique coordination, and the metal centers hold the concave aromatic surfaces of mult

160 ighly distorted CO2 molecule is bound to the metal center in an eta(2)-C,O coordination mode, thus es

161 iled mechanism of mechanical disruption of a metal center in its native protein environment in aqueou

162 requirement for generation of an unsaturated metal center in migration chemistry.

163 complexes and suggests a contribution of the metal center in the catalytic cycle.

164 endo protonated isomers with respect to the metal center in the former, which is essential to attain

165 xed as carbonate and bound to the equatorial metal centers in both the Zn5 L6 and Cd5 L6 assemblies,

166 xidative addition of aryl halides across the metal centers in Cu(I) and Pd(II) organometallics that i

167 monstrate the marked effect of electron-rich metal centers in enabling higher oxidation state pathway

168 lts demonstrate the important role of distal metal centers in modulating the reactivity of a terminal

169 tly been limited to coordinatively saturated metal centers in octahedral ligand environments.

170 ce rule" that each triangle must contain two metal centers in one spin state and one in the other.

171 ings have been made with as many as fourteen metal centers in the cyclic structure.

172 in (S = 1/2) electronic configuration of the metal centers in the desolvated framework is supported b

173 = 89200 g.mol(-1)) composed of d(5)-vanadium metal centers in the main chain, making it a rare exampl

174 presence of a cooperative effect of the two metal centers in the transformation of CO2.

175 lies in the very different geometries of the metal centers in the transition state.

176 lear metal aggregates containing two or more metal centers in which dinitrogen is coordinated or acti

177 Metal centers in X-ray structures of small organometalli

178 be used to modify the redox activity of the metal centers, including changing the functionalization

179 In all examples, the incorporation of the metal center into the pincer ligand decreases the NICS(1

180 t on the successful incorporation of the tin metal center into the zeolite framework.

181 The incorporation of metal centers into the backbone of polymers has led to t

182 llic clusters enabled differentiation of the metal centers involved in oxygen atom transfer (Mn) or r

183 e in volumetric adsorption capacity when the metal center is changed.

184 r palladium complexes, wherein only a single metal center is directly involved in the catalysis.

185 In its perfect crystal structure, each Zr metal center is fully coordinated by 12 organic linkers

186 facile reductive elimination from the nickel metal center is induced via a photoredox-catalyzed elect

187 The metal center is not directly involved in the catalytic b

188 Thus, the choice of metal center is shown to be crucial in determining the l

189 ile a mainly d(z)(2) orbital centered on the metal center is the corresponding donor.

190 r (FLP) solely constructed around transition metal centers is described in this work.

191 omometallic ring containing an odd number of metal centers is reported.

192 n catalyst containing only vanadium atoms as metal centers is reported.

193 ahedral coordination of the metalloporphyrin metal center, leading to a longer electron pathway of lo

194 ulations that show that modifications to the metal center, ligand, or even tuning the overall binding

195 hat chloride binding triggers changes in the metal center ligation: chloride binding induces the prop

196 vide three MTAPc complexes bearing different metal centers (M = Cu(2+): CuTAPc, M = Zn(2+): ZnTAPc, a

197 CT)-state quenching by low-lying nonreactive metal-centered (MC) states.

198 trong antiferromagnetic coupling between the metal centers, mediated by the oxo groups, exists in the

199 With tunable pore size and rich active metal centers, metal-organic frameworks (MOFs) have been

200 ionships that the existence of two different metal centers not only facilitates successful constructi

201 a feasible ligand that can coordinate to the metal center of Cp*RhCl to accelerate the cleavage of th

202 suggest that the binding of chloride to the metal center of HctB leads to a conformational change in

203 ases with decreasing electron density at the metal center of the Ir catalyst, but that the rate of be

204 ive to the degree of electron density at the metal center of the Ir catalyst.

205 nt of substrate discrimination at the buried metal centers of metalloenzymes.

206 ons, enabled selective interactions with the metal centers of phthalocyanines 7, 12, 9, and 15.

207 ion that HoxR avoids oxidative damage of the metal centers of the MBH, in particular the unprecedente

208 Although such metal centers of uniform oxidation states have been achi

209 ing - coordination of Lewis basic atoms into metal centers often necessitate elevated temperature, hi

210 Rational, systematic tuning of single-site metal centers on surfaces offers a new approach to incre

211 tion of electron density from the transition-metal center onto the cage.

212 e(-) ORR pathways was achieved via different metal centers or neighboring metalloid coordination.

213 narrow energy range, corresponding to either metal-centered or ligand-centered oxidations, which we i

214 ators, we use here porphyrins with different metal centers, or lacking a metal center.

215 ers a proximal (3-substituent closest to the metal center) over a distal (3-substituent furthest from

216 PP1 inhibition involves metal center oxidation rather than the thiol oxidation t

217 ery oxidation-resistant, yet promotes facile metal-centered oxidation to form stable Ir(IV) compounds

218 , and DFT calculations, all of which confirm metal-centered oxidation.

219 action and Mossbauer spectroscopy indicate a metal-centered oxidation.

220 s-orbitals participate on the bond with the metal center, paving the road toward novel coordination

221 ahedral cage connected to a single exohedral metal center (POBBOP)Ru(CO)2 (POBBOP = 1,7-OP(i-Pr)2-2,6

222 ) electrochemical cells demonstrate that the metal center preferentially reduced and its location in

223 (2) formation via NH(2) coupling between two metal centers presents an attractive strategy for AO cat

224 t a high catalytic activity by isolating the metal center, preventing bimolecular decomposition paths

225 g such poor ligands, meaning that binding at metal centers prior to C-H activation is disfavored.

226 on takes place stereoselectively anti to the metal center, producing exclusively cis-disubstituted pr

227 opriately sized linkers between carbon and a metal center provides a means to modulate the length and

228 luation of their reactivity toward different metal centers provides evidence that the dicationic frag

229 operties expected for M(II) species and with metal-centered radical character.

230 ge of a C-H bond is accomplished by a single metal-centered radical.

231 competes with substrates for binding to the metal center, rationalizing its inhibitory effect.

232 high accuracy is essential for understanding metal center reactivity, as even small structural change

233 lophen)] results in both ligand centered and metal centered reduction affording the Co(I)-Co(II)-Co(I

234 cert with DFT calculations suggest a largely metal centered reduction of 1 to form the low spin (S =

235 i, Na, K) leads to either ligand-centered or metal-centered reduction depending on the alkali ion.

236 The observed metal-centered reduction leads to distinct reactivity pa

237 the interactions controlling the geometry at metal centers remain often elusive.

238 omplex possesses an unpaired electron on the metal center, rendering it likely that catalysis takes p

239 ethyl (OH-CH2-) moiety of 5hmC points to the metal center, representing the reaction product of 5mC h

240 Its two metal centers require an elaborate assembly machinery th

241 Specifically, in the crystal phase a Pt(IV) metal center resulting from Fe <-- Pt backward electron

242 the magnetic reorientation of the transition metal center, resulting in a re-hybridization of molecul

243 bears a tethered pyridine that binds to the metal center, resulting in an Ir(eta(5):kappa(1)-C(5)Me(

244 n: association of the target analytes to the metal center results in approximately 1000-fold enhancem

245 In metalloproteins, metal centers serve as active sites for a range of funct

246 R region corresponding to the characteristic metal-centered spin-flip Cr((2)E -> (4)A(2)) and Cr((2)T

247 nsfer ((1)MLCT) excited state into a quintet metal centered state ((5)MC) as has been observed for pr

248 s to efficient nonradiative deactivation via metal-centered states.

249 ation of the (3)MLCT state through low-lying metal-centered states.

250 work features the importance of the relative metal-centered stereochemistry.

251 by adding sufficient electron density to the metal center such that it became the thermodynamically p

252 t observation of three key components, i.e., metal center, support and substrate, is achieved, provid

253 -O) core induces a cascade wherein all three metal centers switch from high-spin Fe(3+) to low-spin F

254 oxidation state and structure of single-site metal centers that are in contact with a metal surface m

255 imetallic vertices, as opposed to the single metal centers that typically serve as structural element

256 a targeted oxidative inactivation of the PP1 metal center, that sustains eIF2alpha phosphorylation to

257 e myriad binding modes of heterocumulenes to metal centers, the monometallic kappa(2)-ECE (E = O, S,

258 ccommodating more than one Li per transition-metal center, thereby yielding higher charge storage cap

259 When paired with a rhodium metal center, these bis(diazaphospholane) ligands are hi

260 le oxidative reactions at a formally Ir(III) metal center through a hydrazido(2-)/isodiazene valence

261 Mn(II) precursor results in oxidation of the metal center to a Mn complex with concomitant assembly o

262 to the basic heteroatom directs the reactive metal center to a specific C-H bond.

263 tion on nitric oxide activation by an Fe(II) metal center to be studied.

264 er affords the proper stereochemistry at the metal center to facilitate essentially irreversible DNA

265 to attain suitable proximity to the reduced metal center to generate H2.

266 nduces migration of a benzyl ligand from the metal center to the C(carbine) atom.

267 nce of the migration of the hydride from the metal center to the Calpha atom of the alkylidyne.

268 nsfer of electron density from the catalytic metal center to the CO ligand oriented trans to the alky

269 t is accompanied by charge transfer from the metal center to the organic substrate.

270 it is found that Fe and Co are the best MHP metal centers to catalyze these reactions.

271 n and the stoichiometric ratio of rare-earth metal centers to ligands, a hierarchic assembly with dod

272 gen cleavage and hydrogenation by transition-metal centers to produce ammonia is central in industry

273 The ability of redox-active metal centers to weaken the bonds in associated ligands

274 l oxygen atom could be rotated away from the metal center, to a hydrophobic pocket formed by Ala212,

275 ndicating organic character in formerly pure metal-centered transitions.

276 d quintet state is postulated to occur via a metal-centered triplet state, but this mechanism remains

277 (eta(6) -C(6) H(6) )Mo(CO)(3) regarding the metal-center valence state and electronic population of

278 l results demonstrate that modulating a base-metal center via a covalently appended Lewis acidic supp

279 lts demonstrate that modulating a transition metal center via a direct interaction with a Lewis acidi

280 wed by chloride delivery from Me3SiCl to the metal center via a six-membered transition state (IV) th

281 The coordination of H2 to a metal center via polarization of its sigma bond electron

282 ct binding, as well as the inhibition of the metal center via reversible coordination of either a sub

283 rbocation that is coordinated to the iridium metal center via the key allene moiety.

284 The preferred gas adsorption on the metal center was confirmed by neutron diffraction measur

285 state for transfer of the S-H proton to the metal center was located with a computed free energy of

286 n complexes displaying a site-differentiated metal center was synthesized.

287 three formal multiply bonded ligands to one metal center where the coordinated heteroatoms derive fr

288 he transfer of electrons to the redox active metal centers where O2 is reduced to water.

289 sulfenic acids (P-SOH) or the involvement of metal centers which would facilitate the oxidation of H2

290 ironment and the nature of the spin-carrying metal center, which is further subject to modifications

291 s a rare example of formal N-N coupling on a metal center, which likely occurs through an electrocycl

292 aramagnetic species, and to bind strongly to metal centers, which gives rise to very robust catalysts

293 attice oxygen atoms to reoxidize the reduced metal centers while the gaseous O2 reactant replenishes

294 aves were attributed to the oxidation of the metal centers, while the remaining one is due to the oxi

295 electronic structure consisting of a Mn(III) metal center with a noninnocent OIM diradical ligand.

296 exchange of THF molecule coordinating to the metal center with isonitrile, whereas insertion of isoni

297 te electron transfer from chloride to the Ru metal center with rate constants in excess of 10(10) M(-

298 lar, those related to the interaction of the metal centers with the interstitial atom.

299 ones for a delicate geometric control at the metal center, with a network of weak interactions within

300 eavage processes occurring at the transition-metal center would facilitate the development of catalyt