ライフサイエンスコーパス: metastable

1 thermodynamically stable and the E isomer is metastable.

2 viously accepted martensitic ground state is metastable.

3 ferable, although the Toth structure remains metastable.

4 Catalytic materials tend to be metastable.

5 on dislocation lines due to the migration of metastable {111}beta1/{110}Mg.

6 , all of which supersede the occurrence of a metastable 19-stranded scaffold.

7 Metastable 1T(1T') phases require higher formation energ

8 Confined metastable 2-line ferrihydrite, stable at ambient temper

9 functional role to intrinsically generated, metastable activity.

10 The process by which metastable aggregates are destabilized and transformed i

11 tic algorithm, we uncover the structure of a metastable Al(41)Sm(5) phase that supplements its family

12 ere we introduce, for the first time, a bulk metastable Al-Mg supersaturated solid solution by the di

13 oy with the B2 (CsCl-type) structure and the metastable Al9Ni2 phase.

14 The metastable alloy Sn(x)V(1-x)Se(2) was preferentially for

15 ss was achieved homogeneously throughout the metastable alloy with a record maximum supersaturated Mg

16 rate the synthesis of a bulk nanocrystalline metastable alloy with good microstructural stability at

17 d seems to originate from instability of the metastable AlxMy compound, in which significant inhomoge

18 The activated state is metastable and decays to the original precursor reversin

19 e efforts is the spike (S) protein, which is metastable and difficult to produce recombinantly.

20 nception of pluripotency as an intrinsically metastable and precarious state.

21 This study reports that metastable and temperature-sensitive chemically exfoliat

22 The lipid replicators are metastable and their out-of-equilibrium population can b

23 -SiC, preferred for nuclear applications, is metastable and undergoes a phase transformation at high

24 natural tiles' or Voronoi polyhedra that are metastable and, consequently, temporally persistent.

25 exhibit a smooth crossover between isolated (metastable) and disordered lattice configurations across

26 Above 8 AL, the gamma-SnTe phase becomes metastable, and can convert irreversibly to the bulk roc

27 le magnetic structure that we associate with metastable antiferromagnetism.

28 niscent of diborane, is also predicted to be metastable at this pressure.

29 of Au {001} surface with the formation of a metastable Au(4)S(4) interfacial phase which is stabiliz

30 pressure monoclinic phase, thermodynamically metastable below about 3 GPa, shows a calculated negativ

31 is of the formation of twisted crystals of a metastable benzamide polymorph (form II) crystallizing f

32 rthermore reveals an unexpected abundance of metastable beta-S(8) and gamma-S(8), in addition to the

33 and unveil the role of chemically activated, metastable (BH(3) -HCOO)(-) centers that display more th

34 ing the orthosteric binding site (OBS) and a metastable binding site (MBS) within the same receptor u

35 Metastable binding sites may provide a new source of all

36 tline the concept of bitopic ligands, review metastable binding sites, and discuss their potential as

37 ransient, low-affinity binding sites, termed metastable binding sites.

38 to quantify, in situ, the concentration of a metastable bioanalyte toward predicting tumor drug sensi

39 g, at multiple length scales, was noted in a metastable body-centered cubic (bcc) beta-titanium alloy

40 and present compelling support for not only metastable but also thermodynamically stable multimeric

41 tylene clusters with n > 3, as well as other metastable C6H6(+) isomers.

42 es reovirus disassembly and how perturbing a metastable capsid can compromise replicative fitness.IMP

43 Predictions indicate that these metastable carbon polymorphs, which contain odd-numbered

44 m (DTP) nanostructures carrying two pairs of metastable catalytic hairpin assembled (CHA) probes, AS1

45 rest coincides with massive aggregation of a metastable chaperone-activity reporter.

46 rs in which fibers form as well as for their metastable character.

47 with an energetic molecular beam, was into a metastable chemisorption state.

48 "Hidden phases" are metastable collective states of matter that are typicall

49 se TIA1 spontaneously oligomerizes to form a metastable colloid-like suspension.

50 gregation-prone (306)VQIVYK(311) motif forms metastable compact structures with its upstream sequence

51 oprotein (Env) trimer [(gp120/gp41)(3)] is a metastable complex expressed at the surface of viral par

52 To synthesize new or metastable complex oxides, kinetically competent reactio

53 ng parameters often prevent the synthesis of metastable compounds.

54 discrete polyphenic traits in epigenetically metastable conditions can contribute to a cancer-prone s

55 ts to maintain mature signaling kinases in a metastable conformation permissive for signaling activat

56 Several metastable conformations present a cryptic drug-binding

57 The structure presents two metastable conformations separated by a free energy barr

58 ict that a high vacancy concentration on the metastable CoO(2) termination enables a vacancy-assisted

59 port the first evidence of the conversion of metastable cross-alpha-helical crystals to thermodynamic

60 ts indicate that uranium can prefer to be in metastable crystal forms (i.e., alpha-UO(3)) that have h

61 This, combined with several metastable crystal phases and stoichiometries and the lo

62 Access to metastable crystal phases is limited as their direct syn

63 ve nanoparticles having unique compositions, metastable crystal structures, and complex heterostructu

64 re synthesized in either cubic or hexagonal (metastable) crystal structures and used as the host mate

65 aining a reasonable thermal stability of the metastable cyclophanediene isomer.

66 samples with a significant retention of the metastable diamond phase.

67 onstrate the solution phase synthesis of the metastable distorted octahedrally coordinated structure

68 ethod for controlling the oligomerization of metastable DNA hairpins using the hybridization chain re

69 By designing metastable DNA hairpins with shape-defining intramolecul

70 We identify a metastable domain in the global network phase diagram sp

71 Nanoindentation of three metastable dual-phase high entropy alloys (HEAs) was per

72 These materials are often metastable during irradiation, returning to their pre-ir

73 echanism for triplex formation and uncover a metastable, dynamic triplex population under near-physio

74 These metastable dynamics accord with empirical data from mult

75 ctivity, such as its intrinsically generated metastable dynamics.

76 on, a result that suggests that formation of metastable electron donor-acceptor complexes provides a

77 re we report the observation of a long-lived metastable electronic state in an HCI by measuring the m

78 etical framework to reveal the nanoscale and metastable energy landscapes of Pourbaix (E-pH) diagrams

79 their seasonal variations, drive the fate of metastable ENMs.

80 The metastable Env is triggered to undergo entry-related con

81 ceptors CD4 and CCR5 on the target cell, the metastable Env trimer is triggered to undergo entry-rela

82 lammatory signaling and highlight VCAM1 as a metastable epiallele.

83 also found strong evidence for enrichment of metastable epialleles among subthreshold signals in the

84 nder such chemically disordered SSs rare and metastable, except at very high temperatures.

85 while the latter with f-f transition has no metastable excited state above 10,000 cm(-1), which requ

86 decompression to ambient pressure, yielding metastable fcc-hcp mixtures.

87 The metastable ferromagnetic phases of LaTcO(3) and LaPtO(3)

88 report results of stability analysis of the metastable fertile forest state.

89 e as a principal gatekeeper between a native metastable folded state and the amyloid state.

90 roduction to favor the more bioavailable but metastable Form I with limits of detection in the ppm re

91 claulansine D in the solid state exists in a metastable form, and after an induction period of 30-90

92 v-activating ligands gradually guides Env to metastable forms that expose cryptic epitopes and that a

93 ginal models can show stable, divergent, and metastable (fragile) dynamics.

94 f the virus triggers the dissociation of the metastable Gn-Gc lattice to enable insertion of the Gc-r

95 g gold-gold atom coupling and water-mediated metastable gold complexes.

96 hat the rocksalt-type phase is substantially metastable (>70 meV/atom) compared to the wurtzite-type

97 s, revealed that these PBIs form kinetically metastable H-aggregates, which can be transformed into t

98 biosensor of proposed method is as follows: Metastable hairpin probe H(1) was modified on electrode

99 sequently, the bubble collapses and releases metastable He[Formula: see text] at the droplet surface.

100 ribe purification of full-length recombinant metastable helical nucleocapsid of Hantaan virus (Hantav

101 e design of numerous alloys, yet research on metastable high-entropy alloys is still in its infancy.

102 ersible oxidation processes that produce two metastable "high-valent" CuOH species, which can be gene

103 is challenging to obtain particularly using metastable hosts, such as metal-organic frameworks (MOFs

104 Zincblende MnS and CoS, which are metastable in bulk, retain both the tetrahedral cation c

105 f ALS result from a set of proteins that are metastable in motor neurons, and thus prone to aggregati

106 The rational synthesis of metastable inorganic solids, which is a grand challenge

107 rotation of the central gamma-shaft, with a metastable intermediate located-consistently with recent

108 the inactive and active states-at least two metastable intermediate states.

109 r-intuitive lattice rearrangement involves a metastable intermediate that results from solvent remova

110 athways comprising distorted Li polyhedra in metastable intermediates along two-phase boundaries.

111 scale regime and the generation of reactive, metastable intermediates improve the CO(2) uptake proper

112 um crystallization pathway through different metastable intermediates.

113 oscopy showed that the relative abundance of metastable iron-sulfur mineral phases (FeS(x)) increased

114 ort appears to be general, implying that the metastable isomer of a photoswitch can be isomerized to

115 ded to other systems for synthesizing novel, metastable layered structures with new functionalities.

116 crystalline phase of bismuth can melt into a metastable liquid below the melting line through a decom

117 n prevents the investigation of water in its metastable liquid form.

118 to supercooled liquid, the pressure-induced metastable liquid may be more ubiquitous than we thought

119 A metastable liquid may exist under supercooling, sustaini

120 a kinetic mechanism which proceeds through a metastable liquid phase.

121 We show that both models have a metastable liquid-liquid critical point at deeply superc

122 The possible existence of a metastable liquid-liquid transition (LLT) and a correspo

123 e solid may directly melt into a sustainable metastable liquid.

124 s driven by a bulk instability introduced by metastable LLPS exposed to an ion-activated attractive s

125 encies cannot coalesce readily, resulting in metastable, long-living droplets.

126 ralizing taxa, such as stony corals, deposit metastable, magnesium-rich, amorphous calcium carbonate

127 These fluctuations induce the formation of metastable magnetic domains evolving into a single macro

128 Metastable memory is then converted to stable epigenetic

129 The metastable metallic and small band gap phases of group V

130 in the 1T-TaS2 is driven by coupling to the metastable metallic phase coexisting within the Mott com

131 using the C35S mutant of TRX, which formed a metastable mixed disulfide bond with TG2, we demonstrate

132 We determine the structure of the metastable monoclinic metal phase, which exhibits antife

133 overexpression of MRE11 compensates for the metastable Mre11-Nbn(mid8) interaction, and that selecti

134 cales and show that the kinetically arrested metastable multi-droplet state is a dynamic outcome of t

135 o act as a firm 'handle' for the assembly of metastable mutant SUR1-Kir6.2 complexes.

136 to a snap trap, the protein transits from a metastable native form to a relaxed triggered or induced

137 se inhibitors (serpins), typically fold to a metastable native state and undergo a major conformation

138 tions along the bilayer normal establish the metastable nature of the inserted pore, yielding a force

139 wder diffraction studies, which revealed the metastable nature of the products of oxidative eliminati

140 inding to acetylene through the formation of metastable [Ni(II)(C(2)H(2))(3)] complexes.

141 be extended to include a broader match with metastable, non-crystalline structural motifs.

142 3PyS)]BF4 (1) leads to the production of the metastable nonheme {FeNO}(8) complex, [Fe(NO)(N3PyS)] (3

143 sing density functional theory, we find that metastable O precursors to the CuO phase can account for

144 CRES transitioned into a metastable oligomer that was resistant to aggregation an

145 Thus, metastable oligomers antagonize their replacement by amy

146 ken together, our studies suggest that early metastable oligomers may serve as building blocks for fu

147 assemble into both rigid amyloid fibrils and metastable oligomers termed AbetaO or protofibrils.

148 ore stable phase grows at the expanse of the metastable ones.

149 s and 2D ice have been imaged, capturing the metastable or intermediate edge structures involved in t

150 phosphorus negate the possible formation of metastable or low temperature phases.

151 Recently, metastable or possibly stable nanometric aqueous cluster

152 l structure, which can form below either the metastable or the spinodal region of the phase diagram.

153 Here we report the direct synthesis of metastable ordered intermetallic Pd(31)Bi(12) at room-te

154 signature is used to follow the emergence of metastable organometallic intermediates and their conver

155 reducing glass matrix in the red stripe or a metastable overoxidized glass in the purple stripe.

156 ts into the size-dependent thermodynamics of metastable oxide nucleation and growth in water.

157 h- (HDL) and low-density liquid (LDL) in the metastable part of the phase diagram.

158 SNF generates a multitude of nucleosome-like metastable particles termed "remosomes".

159 sis confirms a close correlation between the metastable pattern and ferroelectricity.

160 Here, we report that a designed metastable pattern of octahedral rotation leads to robus

161 ctional theory, we selectively stabilize the metastable pattern, distinct from the equilibrium patter

162 ands suggested the major contribution of the metastable pharmacophore to be a hydrophobic interaction

163 in phase selection, and the richness of the metastable phase landscape accessible from the glassy st

164 ed material properties associated with a new metastable phase of monoclinic symmetry within bulk KNbO

165 athway to bulk-scale Mo(2)AlB(2), which is a metastable phase that has been predicted to be the precu

166 ic layers with the formation of a reversible metastable phase that only exists during catalytic react

167 dal synthesis to enable the formation of the metastable phase.

168 WTe(2), leading to a topologically distinct metastable phase.

169 2H domains dominate, with nuclei of a second metastable phase.

170 s to create a snapshot of ion diffusion in a metastable phase.

171 The emergence of metastable phases can thus be promoted by templating cry

172 Without a precise understanding of which metastable phases form, or their lifetimes, targeted syn

173 Strategies involving metastable phases have been the basis of the design of n

174 pinning of the crystallographic structure in metastable phases induced by the exfoliation process.

175 ch works like a "wiper blade" to correct all metastable phases into thermodynamically stable phases a

176 Moreover, a variety of metastable phases were predicted, such as the covalent C

177 L) and gas-like (GL) supercritical water are metastable phases, and that the so-called Widom line zon

178 fferent materials providing direct access of metastable phases.

179 l mechanisms that can drive the synthesis of metastable phases.

180 e, and that there also exists a hierarchy of metastable phases.

181 Metastable phenotypic state transitions in cancer cells

182 The arising metastable point defect population explains a common roo

183 Attributed to a light induced metastable polar distortion uniquely enabled by the FeSe

184 This metastable polar phase, observed up to temperatures exce

185 Polyphthalaldehyde is a metastable polymer that can rapidly and quantitatively d

186 s are observed, including a stabilization of metastable polymorphs, a depression of freezing points,

187 e common for other molecular crystals having metastable polymorphs.

188 ecruitment of Cdc24, but not Bem1, induces a metastable pool of Cdc42 that is sustained by positive f

189 unified energetic and mechanistic picture of metastable pore defects in tensionless lipid membranes.

190 nucleation mechanism and energetics of small metastable pores and illustrates a systematic approach t

191 oduce recombinant hMPV F glycoprotein in the metastable pre-fusion conformation has hindered structur

192 conformational change, transitioning from a metastable pre-fusion conformation to a more thermodynam

193 These structures likely represent metastable precursors of the ripple phase that vanished

194 ng this fusion process F is converted from a metastable prefusion conformation into an energetically

195 the endosome triggers a transition from the metastable prefusion conformation to the stable fusion c

196 dynamic polymerization networks that exploit metastable prion cross-beta phases.

197 ike or right-handed helix superstructures as metastable products, depending on the nature of the gues

198 wever, we demonstrate that this structurally metastable protein possesses superior voltage-gated chan

199 ein homeostasis system associated with these metastable proteins by using a gene coexpression analysi

200 Metastable proteins tend to populate misfolded species t

201 Superoxo 4 converts to a metastable putative Fe(III)-OOH intermediate, at rates t

202 architecture of natural photosystems, and by metastable radical pair formation when photovoltaic reac

203 Here, we propose that a metastable radical state, nonreactive with oxygen, safel

204 The developed methodology for studying metastable reaction intermediates prepared with a high-e

205 ts-on-a-vine' arrangement, by exploiting the metastable region of the phase diagram of thermally resp

206 In the metastable region, just below the phase separation tempe

207 rst time: a) Identification of four distinct metastable regions along the activation pathway, b) Kine

208 inorganic CsPbI(3) perovskite black phase is metastable relative to its yellow, nonperovskite phase a

209 Though p-G(2) BDS is formally metastable relative to the "collapsed", nonporous polymo

210 The metastable replicator persists at a higher concentration

211 irect probe of the vibrational structure and metastable resonances that are characteristic of the rea

212 d further report that MxA forms membraneless metastable (shape-changing) condensates in the cytoplasm

213 atus, we report that MxA formed membraneless metastable (shape-changing) condensates in the cytoplasm

214 surface-mediated formation of radicals over metastable sites, and their sequential propagation in th

215 n processes, such as sudden densification of metastable slab.

216 (around 5-10 h) involves the formation of a metastable solid (presumably ZnHPO(4)), which later evol

217 work out a microscopic mechanism by which a metastable solute-rich phase can readily nucleate in a l

218 40 degrees C resulting in the formation of a metastable species (2).

219 ither unstable transient species or exist as metastable species in equilibrium with a dimeric form, u

220 ransition metal ions, the reactivity of this metastable species is arrested by the presence of an int

221 investigated at -90 degrees C, generating a metastable species, 2.

222 he free energy of both the stalk barrier and metastable stalk, which is not trivially explained by mo

223 mphimedon queenslandica exist in a transient metastable state and readily transdifferentiate into arc

224 s toward low oxygen chemical potential, this metastable state and the resulting enhanced selectivity

225 w tube with a contractile sheath loaded in a metastable state by a baseplate scaffold(1,2).

226 R) spectroscopy shows that the photo-induced metastable state can be generated within 150 ps at 190 K

227 und polymer molecules, releasing them from a metastable state into the thermodynamically favoured cry

228 ended in the aqueous core suggests that this metastable state may persist for a significant fraction

229 s transition is explained by an intermediate metastable state occurring in the transient diffusion pr

230 We consider escape from a metastable state of a nonlinear oscillator driven close

231 hrough active nitrogen species and becomes a metastable state of the catalyst (State I); next, organi

232 n frequency ratio of the ground state to the metastable state of the ion with a precision of 10(-11)-

233 embly and also were required to maintain the metastable state since following dilution the oligomer w

234 w fs, or slow, if the energy is trapped in a metastable state that decouples from its environment.

235 cells is mediated by membrane proteins in a metastable state that transition to a more stable state

236 The second longest-lived metastable state was an unfolded, compact monomer with l

237 om the experimentally observed half-zippered metastable state, the SNAREpins have to mechanically syn

238 ally work by keeping the fouling liquid in a metastable state, with trapped pockets of air between th

239 6 analogues may facilitate enrichment of the metastable state-1 Env conformation for structural chara

240 ng is induced by photoisomerisation to their metastable state.

241 ere a high density of domain walls creates a metastable state.

242 t free-energy path between two longest-lived metastable states and confirm earlier findings of non-tw

243 al models is challenging, even if only a few metastable states are involved.

244 mulas for the locations and probabilities of metastable states as a function of the parameters descri

245 dominant equilibrium state augmented by two metastable states associated with surface bound dimers a

246 history drives the material into long-lived metastable states defined by self-assembled particles wi

247 ying assumption was that multiple stable and metastable states exist for different GB orientations(4-

248 d kinetics and predict previously unobserved metastable states for Ising models and protein simulatio

249 switch function, revealing the importance of metastable states for RNA-based gene regulation.

250 have identified three additional long-lived, metastable states from the bin-based model.

251 a nontrivial connectivity between different metastable states in the underlying physical system.

252 However, urea efficiently perturbs metastable states induced by cold and CD4Ms and increase

253 otein assemblies, where the number of global metastable states may grow exponentially with the system

254 the HA prefusion structure (and perhaps the metastable states of other viral entry proteins) is more

255 imilar to ambient conditions, we observe two metastable states of the salt: the contact (CIP) and the

256 an exhaustive structural characterization of metastable states on the basis of tertiary contact maps

257 In addition, unusual metastable states with longitudinal domain walls along P

258 e global thermodynamic minimum by populating metastable states, from which energy can be transferred

259 trained optimization eliminates intermediate metastable states, indicating that flux is enhanced in m

260 ed and analyzed when they only possess a few metastable states, such as small- to medium-sized protei

261 morphism and transitions between its various metastable states, through fine-tuning of molecular pack

262 These require the involvement of metastable states, which are either able to approach the

263 nse and links uncertainty in the ordering to metastable states.

264 a into a number of dynamic processes between metastable states.

265 tion timings between two genes and identify 'metastable' states-discrete cell types along the continu

266 can proceed via multiple transformations of metastable structures along the pathway to the thermodyn

267 These metastable structures are of vital catalytic importance,

268 Arguing that kinetically accessible metastable structures might be more biologically relevan

269 pose that these short hairpins correspond to metastable structures that are transiently formed during

270 essure structure (for Pb(4)S(3)I(2)) and two metastable structures that had not yet been reported (fo

271 eins function by navigating between multiple metastable structures using bond rotations of the polype

272 ormed an unusually large number of different metastable structures, including all of those previously

273 stems, in maintaining the homeostasis of the metastable subproteome associated with Alzheimer's disea

274 iseases has been hypothesized to depend on a metastable subproteome vulnerable to aggregation.

275 aggregation-prone proteins, which make up a metastable subproteome.

276 finition of a brain state as an ensemble of "metastable substates," each with a probabilistic stabili

277 These patterns are metastable, such that multiple spatiotemporal wave patte

278 ical processing conditions and comparable to metastable superionic Li(7) P(3) S(11) .

279 s driven by the autocatalytic formation of a metastable surfactant whose breakdown products are conve

280 emical vapor deposition technique to explore metastable synthesis of boron-rich boron-carbide materia

281 re rapidly in the spinodal region, below the metastable temperature, T (meta) , and a small positive

282 istinct Polycomb components to deliver first metastable then long-term epigenetic silencing.

283 t-principles calculations, we discover a new metastable three-dimensional carbon allotrope entirely c

284 e selective synthesis of two closely related metastable tin vanadium selenides via near-diffusionless

285 ynthetic conditions for the stabilization of metastable TMD crystals and at stimulating future advanc

286 irreversible transition was observed from a metastable to a stable crystal phase within the nanostru

287 The formation of a metastable trans-complex, catalyzed by HOPS and its SM s

288 ferentiation (the long-lived plasma cell) or metastable transcriptional reprogramming (germinal cente

289 omponents of respiratory complexes, with the metastable transmembrane domains (TMDs) of rhomboid subs

290 y tuning the matrix phase's instability in a metastable TRIP-assisted dual-phase HEA.

291 proton-disordered phase which is kinetically metastable, unable to reach, spontaneously, the ferroele

292 The metastable uncapped forms of recapping targets redistrib

293 alpha-phase is a high temperature polymorph, metastable under ambient conditions.

294 elope glycoprotein (Env) trimer maintain the metastable unliganded form of the viral spike.

295 potentially generalizable kinetic pathway to metastable variants of refractory compounds, including b

296 may be a room-temperature superconductor and metastable when the pressure is released and could have

297 surements confirm that antiferromagnetism is metastable within the otherwise ferromagnetic ground sta

298 tion and handling of the light-sensitive and metastable yellow arsenic (As(4)) is extremely challengi

299 lations, we show that these novel states are metastable, yet long-lived.

300 emonstrated to store thermal energy in their metastable Z isomer liquid phase and release the energy