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1 erindividual variation in bioavailability of
Methoxsalen (
8-methoxypsoralen) after ingestion of the s
2 c inhibitors of the cytochrome P450 pathway (
methoxsalen and ketoconazole).
3 ed after exposure to a photoactive compound (
methoxsalen)
and ultraviolet A light.
4 6 was only weakly inhibited by metyrapone or
methoxsalen (
ID50 > 50 microM).
5 sm were inhibited strongly by metyrapone and
methoxsalen (
ID50 < 1 microM, with DCBN at 30 microM), b
6 Photochemotherapy with oral
methoxsalen (
psoralen) and ultraviolet A radiation (PUVA