ライフサイエンスコーパス: microbiota

1 l intestinal mucosa and microbial community (microbiota).

2 tion collectively called the gut microbiome (microbiota).

3 s of disease-associated dysbiosis across the microbiota.

4 ogical and evolutionary forces shaping plant microbiota.

5 nge stressors may be driven by shifts in the microbiota.

6 d from the core members of the fruit fly gut microbiota.

7 mune-mediated diseases by gut, oral and skin microbiota.

8 mmunologically reactive component of the gut microbiota.

9 d mortality and specific modification of gut microbiota.

10 mpared to women with Lactobacillus deficient microbiota.

11 diversity, and community composition of lung microbiota.

12 mmunocompetent mice and modifies the host GI microbiota.

13 c acid than isolates from women with optimal microbiota.

14 and targets the core members of the bee gut microbiota.

15 antibiotics for 4 weeks to deplete their gut microbiota.

16 range by the presence and composition of the microbiota.

17 d with antibiotics for 4 weeks to ablate the microbiota.

18 sible to profile the composition of the oral microbiota.

19 ort to develop therapies that target the gut microbiota.

20 e and selective in its interactions with the microbiota.

21 the colon to be fermented by the intestinal microbiota.

22 e dependent on both neurons and the resident microbiota.

23 ell antigen receptors even in the absence of microbiota.

24 on and taxonomic assignment of the human gut microbiota.

25 bipolar disorder, and changes in intestinal microbiota.

26 the immune system, and commensal intestinal microbiota.

27 diet resulted in substantial changes in the microbiota 3-mo after the start of the intervention; som

28 After fermentation by gut microbiota, a ten-fold increase in the antioxidant value

29 Comparisons of mammalian gut microbiota across different environmental conditions she

30 The microbiota, acting via secreted factors related to indol

31 The gut microbiota affects tissue physiology, metabolism, and fu

32 Microbiota alpha diversity did not differ among groups.

33 Differences in specific sputum microbiota also associated with T2-low asthma phenotype,

34 ation and toxicant exposure in producing gut microbiota alteration and neurotoxicity.

35 tially confounding prior observations of gut microbiota alterations among persons with HIV (PWH).

36 The gut microbiota and bile acid content were determined in faec

37 edge about the relationship between the host microbiota and cancer and anti-tumor immune response, wi

38 ein, harbour altered endophytic phyllosphere microbiota and display leaf-tissue damage associated wit

39 lity influences the relationship between the microbiota and enteric pathogens, as well as disease out

40 the underlying epithelia by both the normal microbiota and enteric pathogens.

41 utrition (SAM) display immature, altered gut microbiota and have a high mortality risk.

42 ne the interaction between mast cell tumors, microbiota and host immune response.

43 tal epithelial cells but also affect the gut microbiota and host immunity.

44 for investigating mechanisms connecting gut microbiota and host pathophysiology.

45 ntestinal epithelial cells interact with the microbiota and how this is regulated at the gene express

46 Abundant links between the gut microbiota and human health indicate that modification o

47 Gastrointestinal microbiota and immune cells interact closely and display

48 In this study, we characterize the vaginal microbiota and immune factors in pregnant African women

49 Disruption of the intestinal microbiota and immune responses contribute to host susce

50 mpact of Western diet (WD) on the intestinal microbiota and improves postoperative survival BACKGROUN

51 erences in the composition of the intestinal microbiota and in susceptibility to metabolic, autoimmun

52 upt the homeostasis between the host and its microbiota and increase susceptibility to periodontal di

53 ue to an increasing academic interest of gut microbiota and its metabolism, this newly developed plat

54 ossover and exit for characterization of the microbiota and measurement of cytokine levels; primary e

55 When we profiled microbiota and metabolites, we observed significant alte

56 Microbiota and metabolome differed between responders an

57 We characterized changes in the fecal microbiota and metabolome to identify the mechanism of E

58 iet (macronutrients and micronutrients), gut microbiota and mucous barriers (gastrointestinal and res

59 e, and other events and their impacts on the microbiota and on disease risk; reported abnormalities o

60 The relationship between the vaginal microbiota and persistent hrHPV was modified by HIV stat

61 t a strong relation between ARB in human gut microbiota and personal medical history.

62 Here, we simultaneously assess microbiota and single immune cells across the healthy, a

63 s of the complex interaction between the gut microbiota and the brain.

64 on therapeutics that aim to modulate the gut microbiota and the gut-liver axis.

65 ncapsulates the fecal material including the microbiota, and a minor form derived from the distal col

66 stress, alterations to interactions with the microbiota, and defective DNA repair.

67 ue in part to previously unappreciated host, microbiota, and environmental factors.

68 Various behaviors, gut microbiota, and fecal metabolome were assessed at 90 day

69 The vascular miR-204 is sensitive to microbiota, and microbial suppression reversibly decreas

70 Diet alters drugs, the metabolism of the microbiota, and the host.

71 As members of the plant microbiota, arbuscular mycorrhizal fungi (AMF, Glomeromy

72 ealed that, in critically ill patients, lung microbiota are altered and correlate with alveolar infla

73 Changes in community-wide and within-patient microbiota are linked with inflammation, but we find no

74 of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to chron

75 d IBD, and changes in the composition of gut microbiota are seen in both diseases.

76 eyer's patches (PPs)-which depend on the gut microbiota-are chronic(4), and little is known about the

77 totic cells during development and shape gut microbiota assembly after birth.

78 Vaginal microbiota assessments at all visits included Gram stain

79 nococcaceae and Veillonellaceae are the main microbiota associated with fibrosis severity in non-obes

80 s crucial for the prevention of CDI in human microbiota-associated (HMA) mice.

81 microbe interactions, and show only marginal microbiota associations with habitual diet.

82 We studied upper airway microbiota at 1 week, 1 month, and 3 months of life, and

83 ren with JIA; mechanisms by which an altered microbiota at birth and later on in childhood may influe

84 sought to examine the relation of the nasal microbiota at bronchiolitis-related hospitalization and

85 Cancer therapies might also alter microbiota at sites throughout the body.

86 During chronic infections and in microbiota, bacteria predominantly colonize their hosts

87 ueous-based encapsulation formulation with a microbiota-based release mechanism and show that it faci

88 tion and provide insights into the future of microbiota-based therapeutics for CDI.

89 nal impact on the rational design of general microbiota-based therapeutics.

90 However, the mechanistic basis of this microbiota-brain signalling and its physiological releva

91 rs and delivery of substrates to the colonic microbiota by more fermentable particulate fiber.

92 Features of the intestinal microbiota can affect development of the brain, immune s

93 ther diet-triggered metabolic changes in the microbiota can alter drug responses in the host has been

94 ivity (CHS), behavioral disturbances and gut microbiota changes.

95 arge numbers of detectable taxa, and because microbiota characteristics are described in relative ter

96 We examined how gut microbiota characteristics related to use of opioid agon

97 Non-optimal cervicovaginal microbiota, characterized by depletion of Lactobacillus

98 rolonged ART may restore the richness of the microbiota closer to that of HIV-uninfected children.

99 esents one of the most abundant habitats for microbiota colonization.

100 erally cause pro-inflammatory alterations in microbiota communities in the intestine.

101 served altered taxonomic compositions of gut microbiota communities upon SIV infection and at differe

102 The high diversity microbiota, Community State Type IV-B, was the most prev

103 ore divergent responses to each other's soil microbiota compared with closely related plant species.

104 The traditional Socransky microbiota complexes also were evaluated.

105 id not find significant differences in fecal microbiota composition among patients with different IBS

106 Altered gut microbiota composition and function have been associated

107 t dysfunction, including modification of gut microbiota composition and higher local inflammatory rea

108 Fecal microbiota composition and inferred function, fecal SCFA

109 olatile organic compounds (VOCs) reflect the microbiota composition and may provide insight into meta

110 immune cell profiling, complemented with gut microbiota composition and routine clinical chemistry.

111 ucosal immune system through modification of microbiota composition and their interactions with the h

112 fferent time points after infection to study microbiota composition by 16 S rRNA amplicon sequencing

113 Analysis of fecal microbiota composition by 16S ribosomal RNA gene sequenc

114 The role of the fecal microbiota composition for the postoperative disease cou

115 and higher Firmicutes, resembling changes in microbiota composition in nonalcoholic steatohepatitis (

116 The fecal microbiota composition of CD patients, analyzed by GA-ma

117 Microbiota composition of post-UC samples was different

118 imary objective was to determine if baseline microbiota composition or diversity was associated with

119 sted for confounding factors, we found fecal microbiota composition to be associated with development

120 on by regulating macrophage polarization and microbiota composition under homeostatic conditions and

121 While baseline microbiota composition was not predictive of weight loss

122 in subcutaneous white fat, 3) change the gut microbiota composition, and 4) prevent and reverse obesi

123 Stroke alters the gut microbiota composition, and in turn, microbiota dysbiosi

124 Microbiota composition, assessed by 16S rRNA gene amplic

125 at of male patients, which were unrelated to microbiota composition.

126 energy balance, blood metabolomics and fecal microbiota composition.

127 The intestinal microbiota comprises diverse fungal and viral components

128 Integrative analyses revealed the E+ microbiota correlated and co-varied with the metabolomes

129 Gut microbiota data obtained by DNA sequencing are complex a

130 Microbiota data were obtained using 16S ribosomal RNA se

131 a5-deficient mice compromises suppression of microbiota-dependent activation of CD8(+) T cells, resul

132 This is due to a microbiota-dependent increased expression of proinflamma

133 upregulated in an IL-4/IL-13- and intestinal microbiota-dependent manner.

134 Select microbiota-dependent metabolites promoted axon outgrowth

135 obiota transplantation studies, specific gut microbiota-dependent pathways, and downstream metabolite

136 arvest energy by anaerobic respiration using microbiota-derived hydrogen (H(2)) as an electron donor

137 tively, these results show that InsP(3) is a microbiota-derived metabolite that activates a mammalian

138 ta indicate differential trajectories of gut microbiota development in humans and chimpanzees that ar

139 nity assembly, and facilitate development of microbiota-directed therapeutics.

140 The microbiota diversity was either decreased or not differe

141 Amerindian cervicovaginal and introital microbiota diversity were not associated with major chan

142 oid agonists (without antagonists) had lower microbiota diversity, Bacteroides enterotypes, and lower

143 These findings support microbiota-driven approaches to identify patients at ris

144 We discover that maturation of the microbiota drives the development of distinct immune def

145 the gut microbiota composition, and in turn, microbiota dysbiosis has a substantial impact on stroke

146 Microbiota dysbiosis has been linked to major depressive

147 psules in adults with obesity results in gut microbiota engraftment in most recipients for at least 1

148 the importance of the early life window for microbiota-epithelial interactions in the presence of in

149 hesis that structural differences in the gut microbiota explain a portion of variability in weight-lo

150 ntified two anti-tumourigenic strains of the microbiota-Faecalibaculum rodentium and its human homolo

151 ure the diversity of endophytic phyllosphere microbiota for survival and health in a microorganism-ri

152 rtance of maintaining healthy populations of microbiota for the survival, homeostasis, and complete d

153 For this study, we collected microbiota from 2 inbred strains of mice which differ in

154 nd culture-based analysis of the human nasal microbiota from different age groups.

155 Transplantation of microbiota from feces of mice fed the wheat- or ATI-cont

156 Colon mucus segregates the intestinal microbiota from host tissues, but how it organizes to fu

157 sults revealed that transplantation of fecal microbiota from schizophrenic patients into antibiotic-t

158 l microbiota manipulations in the context of microbiotas from humans with inflammatory bowel disease.

159 Microbiota function demonstrated reduced butyrate contri

160 Emerging research demonstrates that microbiota-gut-brain (MGB) axis changes are associated w

161 in the pathogenesis of schizophrenia via the microbiota-gut-brain axis.

162 ive women, women with Lactobacillus dominant microbiota had lower odds (OR: 0.35, 95% CI 0.14-0.89, p

163 bacterial, viral and fungal components; the microbiota has a leading role in shaping (early) immune

164 The gut microbiota has been associated with colorectal cancer (C

165 The commensal microbiota has been implicated in the regulation of a di

166 Intestinal microbiota have been proposed to induce commensal-specif

167 ximately 200 types of bacteria from the oral microbiota have remained uncultured in the laboratory.

168 tibiotic-resistant genes (ARGs) in human gut microbiota have significant impact on human health.

169 d with the patients' and the controls' fecal microbiota, highlighting 78 differentially enriched func

170 Microbiota, host and dietary metabolites/signals compose

171 Microbiota-host-diet interactions contribute to the deve

172 Yet, the drivers and patterns of microbiota imbalance (dysbiosis) in wild animals remain

173 we hypothesized that sucrose can introduce a microbiota imbalance favoring caries to a greater degree

174 We also focus on the processes by which this microbiota-immune-stress matrix may influence centrally

175 sts that omega-3 PUFAs can also modulate gut microbiota impacting WAT function and adiposity.

176 sening is associated with changes in the gut microbiota in a preclinical model.

177 gut hormone FGF19, versus placebo on the gut microbiota in a prospective, phase 2 study in patients w

178 prospects for therapeutic alteration of the microbiota in children with JIA.

179 disease risk; reported abnormalities of the microbiota in children with JIA; mechanisms by which an

180 This role of the microbiota in eliciting protective antibodies to a speci

181 d to better understand the role of the human microbiota in health and disease.

182 cory root inulin-type fructans (ITF), on gut microbiota in healthy adults with habitual low dietary f

183 ging insights into the role of the commensal microbiota in mediating colonization resistance against

184 at and ATIs on severity of colitis and fecal microbiota in mice.

185 The functional role of the microbiota in regulating not only mucosal but also syste

186 support the hypothesis that the presence of microbiota in the airspora indicates the possibility of

187 on of interest in examining the existence of microbiota in the human body and understanding its role

188 contribute to the establishment of commensal microbiota in the infant.

189 s uncovered significant roles for intestinal microbiota in this process, but underlying mechanisms re

190 s, particularly postoperative changes in gut microbiota, in facilitating weight loss and resolving as

191 Unexpectedly, the mice receiving WSB/EiJ microbiota increased adiposity but decreased plasma gluc

192 onize GF mice shows a direct effect of fecal microbiota independent of active liver inflammation or i

193 Microbiota-induced expression of AHR in neurons of the d

194 Most studies focus on how intestinal microbiota influence cancer immunotherapy through activa

195 To test the hypothesis that the residual microbiota influences the severity of colitis caused by

196 A complex microbiota inhabits various microenvironments of the gut

197 sed as a model system for understanding host-microbiota interactions.

198 o substantial progress in understanding host-microbiota interactions.

199 The skin microbiota interacts with the host immune response to ma

200 The gut microbiota is a critical mediator of nutrition and disea

201 The gut microbiota is a vast and diverse microbial community tha

202 onclusion, the structure of the infant fecal microbiota is affected by the maternal H. pylori status

203 However, their role in shaping the mosquito microbiota is not well understood.

204 th, the metabolic potential of the human gut microbiota is still poorly understood.

205 The vaginal microbiota is thought to play a role in modulating risk

206 (IL)-22, induced by colonization of the gut microbiota, is crucial for the prevention of CDI in huma

207 ents, we have used gnotobiotic mice to model microbiota manipulations in the context of microbiotas f

208 , or depletion of the Th17 cell-inducing gut microbiota markedly reduces stress-induced VOEs.

209 We monitored microbiota maturation and associations with subsequent d

210 Thus the microbiota may contribute to type 2 diabetes by generati

211 t urbanization-related changes in the infant microbiota may elevate the risk of asthma and atopic tra

212 t are positioned to have an afferent role in microbiota-mediated modulation of gut sympathetic neuron

213 erman population cohort (KORA) that specific microbiota members show 24-h oscillations in their relat

214 ur emerging lines of investigation: how host-microbiota metabolic partnerships protect against infect

215 ive disorder, but the mechanisms whereby the microbiota modulates mood remain poorly understood.

216 Surprisingly, zoo gorilla microbiota more closely resembled that of zoo chimpanzee

217 f antibiotics on the developing neonatal gut microbiota needs to be precisely quantified.

218 We characterized the skin surface and dermal microbiota of 11 dogs affected by spontaneous mast cell

219 ylori status affects the maternal intestinal microbiota of both mother and newborn.

220 clear whether alterations in the intestinal microbiota of children with celiac disease (CD) cause th

221 arities in taxonomic composition support the microbiota of fungus-growing insects as convergent, desp

222 tibiotic use on the health of the beneficial microbiota of the host, has underscored the weaknesses i

223 We compared microbiotas of sensitized (determined by specific IgE re

224 r an in-depth understanding of the impact of microbiota on human health over the last decade.

225 Targeting the gut microbiota or T cell migration may represent therapeutic

226 d captured the diversity of the immature gut microbiota over time and in response to interventions su

227 Metabolic processes occurring during host-microbiota-pathogen interactions can favorably or negati

228 The caecal microbiota plays a crucial role in chicken nutrition thr

229 Human microbiota plays a key role in human health and growing

230 Accumulating evidence suggests that gut microbiota plays a role in the pathogenesis of schizophr

231 Lean patients demonstrated an altered gut microbiota profile.

232 that confer the capacity to similarly tailor microbiota profiles in vitro.

233 bile acids produced by unique members of the microbiota regulate plasmacytoid dendritic cells and mon

234 bruary 2020) will focus on the mechanisms of microbiota-related functions in health and disease and t

235 g specific microbes, signaling pathways, and microbiota-related metabolites) and risk of colorectal c

236 s to the establishment of a mutualistic host-microbiota relationship that is required to maintain hom

237 es and dynamic changes of the bacterial wine microbiota remain poorly understood, especially in the c

238 cruitment and maintenance of the rhizosphere microbiota remains to be fully elucidated.

239 increased in intestinal epithelial cells of microbiota-replete mice compared with germ-free mice.

240 To reduce rCDI, microbiota-restoring therapies are needed, particularly

241 es the mucous barrier via alterations in gut microbiota, resulting in either disease onset/exacerbati

242 hydrolysable AX are likely also released by microbiota's enzymes in the gut and therefore an indicat

243 suggest a resilience to perturbation of the microbiota's starting profile.

244 AN fecal microbiota showed a compositional predominance of Blauti

245 sthma, the compositional structure of sputum microbiota showed greater deviation from baseline in ICS

246 without substantially affecting homeostatic microbiota-specific Th17 cells.

247 to control in both germ-free or E. coli gut microbiota states was used to quantitate pathway-specifi

248 viation increment in relative abundance) for microbiota statistically significantly (P < 0.05) positi

249 ntified four compositionally distinct sputum microbiota structures.

250 suggest that storage method is important in microbiota studies and that the stabilization device may

251 ies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produ

252 n a rapid diagnostic tool for assessing host microbiota susceptibility to bacterial colonization afte

253 The gut microbiota synthesize hundreds of molecules, many of whi

254 To aid the development of novel microbiota-targeted therapies and to better understand t

255 dietary patterns, we investigate whether the microbiota taxonomic and functional profiles are charact

256 tes from dietary fiber's fermentation by gut microbiota that can affect differentiation or functions

257 e therapeutic avenues that either target the microbiota, the barrier surfaces or the host immune syst

258 and environmental factors affecting the gut microbiota, the roles of gut microbes and their bioprodu

259 Despite its abundance in the gut microbiota, there is limited recognition that PGN could

260 The microbiota thriving in the rhizosphere, the thin layer o

261 Whether and how plants control phyllosphere microbiota to ensure plant health is not well understood

262 Transfer of a hypertensinogenic microbiota to gnotobiotic mice recapitulated the prebiot

263 he building evidence for the contribution of microbiota to human disease has spurred an effort to dev

264 Novel associations of sputum and oral microbiota to immunologic features were observed in this

265 estinal metabolites produced by the host and microbiota to initiate intestinal colonization of avian

266 es single-strand RNA (ssRNA) from intestinal microbiota to promote serotonin production.

267 chanisms of signalling pathways from the gut microbiota to the brain and discuss direct effects that

268 d tick proteins that modulate the vector gut microbiota towards an environment that favours colonizat

269 o assess the safety and feasibility of fecal microbiota transplantation (FMT) and reinduction of anti

270 Our understanding and utilization of fecal microbiota transplantation (FMT) has jump-started over t

271 We tested the effect of fecal microbiota transplantation (FMT) on obesity, and plasma

272 Additionally, gut microbiota transplantation from MIA mice produced behavi

273 en together these results suggest that fecal microbiota transplantation may be a treatment option in

274 ses by treatment with either a healthy fecal microbiota transplantation or defined commensal bacteria

275 Indeed, gut microbiota transplantation studies, specific gut microbi

276 r-infant pairs and patients undergoing fecal microbiota transplantation to evaluate the patterns of a

277 on between Arabidopsis thaliana and the root microbiota under iron deprivation that is dependent on t

278 zii and its interactions with other resident microbiota using targeted 16S sequencing.

279 recently been uncovered as a major source of microbiota variation, potentially confounding prior obse

280 At time of diagnosis, the vaginal microbiota was dominated by Lactobacillus iners or a div

281 ne (PTH) only caused bone loss in mice whose microbiota was enriched by the Th17 cell-inducing taxa s

282 t cause this triad of local effects, the gut microbiota was not affected.

283 An urbanized structure of the airway and gut microbiotas was associated with an increased risk of ast

284 their significant enrichment in the mucosal microbiota, we highlight the roles of Bacteroides specie

285 of the human intestinal mucus layer and gut microbiota, we used bioreactors inoculated with healthy

286 To understand the impact of ART on the gut microbiota, we used the rhesus macaque model of SIV infe

287 Human microbiota were evaluated in lung tissue samples from wo

288 Baseline microbiota were measured in subgingival plaque using 16S

289 inalis, isolates from women with non-optimal microbiota were more inflammatory and produced less lact

290 natural IgG antibodies against the maternal microbiota when antibodies are delivered either across t

291 stronger genotype effect on the rhizosphere microbiota when compared with wild barley genotypes adap

292 tic exposure is linked to alterations in gut microbiota, which has been related to risks of various c

293 indirectly impact the formation of a diverse microbiota, which includes bacterial, viral and fungal c

294 infection due to their altering the colonic microbiota, which is necessary to suppress the infection

295 may influence or interact with the Anopheles microbiota, which may contribute to the impact of wAnga

296 sought to examine associations of house dust microbiota with adult asthma, atopy, and hay fever.

297 of endodermal differentiation driven by the microbiota with profound effects on nutrient homeostasis

298 nary shifts in how plants interact with soil microbiota, with strongly contrasting feedback responses

299 HIV-positive children harbor distinct sputum microbiota, with those dominated by Haemophilus, Moraxel

300 The human microbiota within each organ system is distinct, and the