ライフサイエンスコーパス: microcirculation

1 ring PPCI can be used to assess the coronary microcirculation.

2 that otherwise restricts blood flow into the microcirculation.

3 ess of leukocyte recruitment to the inflamed microcirculation.

4 ore integrated views of islet and pancreatic microcirculation.

5 or later permanent structural changes to the microcirculation.

6 e markedly to the concomitant changes in the microcirculation.

7 flammation, and significantly improved graft microcirculation.

8 hing therapies that strategically target the microcirculation.

9 ischemia, as well derangements in intestinal microcirculation.

10 even for semidilute volume fractions of the microcirculation.

11 is extremely important for maintaining renal microcirculation.

12 thout affecting myeloid cell adhesion in the microcirculation.

13 nduced vasodilatation in the human cutaneous microcirculation.

14 on neurons, without considering the cerebral microcirculation.

15 side-stream dark-field imaging of sublingual microcirculation.

16 is known about the role of S1P in the renal microcirculation.

17 ivated mesenteric venules and inflamed brain microcirculation.

18 g blood cells to vascular endothelium of the microcirculation.

19 ence of MVO indicates a highly dysfunctional microcirculation.

20 owing vascular injury in both the macro- and microcirculation.

21 auses vasoconstriction in the human coronary microcirculation.

22 acute normobaric hypoxia on human macro- and microcirculation.

23 tion improves renal, hepatic, and intestinal microcirculation.

24 are mediated by a modulation of the coronary microcirculation.

25 cific focus on systemic hemodynamics and the microcirculation.

26 ented the lowest IMR, suggesting a preserved microcirculation.

27 ell understood, particularly in the cerebral microcirculation.

28 s sac was determined by studies of the local microcirculation.

29 Pa, much smaller than typically found in the microcirculation.

30 viding tight control of myogenic tone in the microcirculation.

31 ls from in vivo recordings of the sublingual microcirculation.

32 interactions and albumin permeability in the microcirculation.

33 ation in liver function by compromise of the microcirculation.

34 Vasoconstriction was evident in the microcirculation.

35 ates permeation of medicines into the dermal microcirculation.

36 RR measures the vasodilatory capacity of the microcirculation.

37 f microvessels of the central and peripheral microcirculation.

38 effect of coronary stenoses on the coronary microcirculation.

39 nsport and utilization of oxygen through the microcirculation.

40 tory role in maintaining the central macular microcirculation.

41 ads to increase of permeability of the brain microcirculation.

42 ve been done to study the involvement of the microcirculation.

43 sity and flow in small vessels of sublingual microcirculation.

44 tanding of the diseases that affect cerebral microcirculation.

45 y fatty acids in the visceral adipose tissue microcirculation.

46 which might have a protective effect on the microcirculation.

47 ow pulsatility transmitted into the cerebral microcirculation.

48 renal resistive index (P < 0.001) and kidney microcirculation.

49 myocytes are addressed, notably the coronary microcirculation.

50 ransduce nitric oxide bioactivity within the microcirculation.

51 agonists, and cause microthrombosis in liver microcirculation.

52 rized by changes in the pial and parenchymal microcirculations.

53 tem/progenitor cells (HSPCs) on the cerebral microcirculation after ischemia-reperfusion injury (I/RI

54 oxin A4 (15-epi-lipoxin A4), on the cerebral microcirculation after ischemia/reperfusion injury.

55 played accelerated thrombus formation in the microcirculation after local trauma.

56 henotype transformation in the regulation of microcirculation after SAH.

57 ular damage and improves graft viability and microcirculation after transplantation.

58 further decreased HAP which impaired hepatic microcirculation, aggravated parenchymal damage, deceler

59 hepatic sinusoids, perturbations in hepatic microcirculation along with changes in various liver cel

60 show that RESA influences ring-stage Pf-RBCs microcirculation, an effect that is fever-enhanced.

61 kin's stratum corneum (SC) to enter the skin microcirculation and achieve systemic administration.

62 zed at a shear stress typical of that in the microcirculation and after treatment with a myosin-II in

63 w-energy shockwave therapy would restore the microcirculation and alleviate renal dysfunction in reno

64 measure of the vasodilatory capacity of the microcirculation and calculated using the equation: base

65 The microcirculation and contractility of the subtended myoc

66 tify the effect of severe AS on the coronary microcirculation and determine if this is influenced by

67 option for the correction of impaired renal microcirculation and endothelial dysfunction.

68 Diabetes impairs the microcirculation and function of various vital tissues t

69 potential to repair and regenerate the lung microcirculation and have shown promise in preclinical e

70 mia is a blood disorder, known to affect the microcirculation and is characterized by painful vaso-oc

71 normal blood flow and T-cell motion in tumor microcirculation and mapping out programmed-death ligand

72 underappreciated capacity for restoration of microcirculation and molecular and cellular activity aft

73 describe the restoration and maintenance of microcirculation and molecular and cellular functions of

74 VAI that anti-angiogenic therapy can improve microcirculation and oxygen saturation and reduce vessel

75 ole in normal erythrocyte deformation in the microcirculation and participates in maintenance of eryt

76 standing of the relationship between macular microcirculation and peripheral ischemia.

77 characterized by abnormalities in sublingual microcirculation and peripheral tissue perfusion, which

78 The graft microcirculation and portal venous flow were increased b

79 Recent discoveries, especially in the muscle microcirculation and QO2 -to- VO2 heterogeneity, are int

80 clinically available PGE analogue, improves microcirculation and reduces MI/R injury.

81 can break the cycle of injury and enable the microcirculation and renal function to recover.

82 % revealed devastated hepatic and intestinal microcirculation and severe side effects in CLP induced

83 HMP and HR similarly improved cortical microcirculation and significantly reduced maximal serum

84 infection/inflammation requires exiting the microcirculation and subsequent crossing of epithelial b

85 ations highlight the importance of a healthy microcirculation and suggest that restoring impaired mic

86 ta2-deficient mice showed unaltered cerebral microcirculation and the absence of ischemia after PbA i

87 ascular permeability, but alterations in the microcirculation and their evolution over the course of

88 S-Nitrosylation therapy restored the microcirculation and thus improved overall organ perfusi

89 Insulin delivery to muscle microcirculation and transendothelial transport are 2 di

90 gested the presence of disorders in cerebral microcirculation and/or changes in cerebral oxygenation.

91 and kidneys and determining renal function, microcirculation, and accumulation of tubular 4-hydroxyn

92 avior of human CLL cells within the mouse LN microcirculation, and discovered that CLL cells bind to

93 endothelium-restricted Ep4 deletion impairs microcirculation, and exacerbates MI/R injury, irrespect

94 edly improved hepatic inflammation, impaired microcirculation, and fibrosis.

95 pericyte alpha-SMA phenotype transformation, microcirculation, and neurological function in SAH rats.

96 atelet consumption, fibrin deposition in the microcirculation, and tissue damage.

97 lary networks, and fluid handling across the microcirculation are compelling avenues for future inves

98 ful as the roles of similar osmotic pumps of microcirculation are examined in other tissues with narr

99 Arterioles in the peripheral microcirculation are exquisitely sensitive to changes in

100 Abnormalities in the coronary microcirculation are increasingly recognized as an eleme

101 at regulate passage of leukocytes out of the microcirculation are now understood.

102 o examine the role of dietary factors in the microcirculation are required.

103 tudies on its effects on both the macro- and microcirculation are scarce.

104 CD8(+) T cells in the liver microcirculation are visualized making intimate contact

105 Using mucosal microcirculation as an in situ assay, cheek pouch tissue

106 After obtaining systemic and microcirculation baseline hemodynamic variables (time 0)

107 n PPCI-treated patients with STEMI, coronary microcirculation begins to recover within 24 h and recov

108 Differences in microcirculation between the hemispheres in eyes with gl

109 n therapies is to promote integration of the microcirculation between the implanted cells and the hos

110 Endothelial function in macro- and microcirculation, blood pressure, anthropometric measure

111 HES improved liver microcirculation, but exhibited significantly increased

112 Background Variations in lymph node (LN) microcirculation can be indicative of metastasis.

113 The conjunctival microcirculation can be non-invasively imaged and thus e

114 nding of whether pathological changes in the microcirculation can be reversed remains limited by a la

115 Coronary microcirculation cannot be visualized in vivo in humans,

116 HES improved liver microcirculation, cardiac index and DO(2)-I, but signifi

117 oncept, endothelial dysfunction of the renal microcirculation causes albuminuria by increasing glomer

118 totic pressure at which the flow through the microcirculation ceases, the reservoir pressure related

119 or donor-specific antibodies (DSA), C4d, and microcirculation changes (MC).

120 Algorithm-based analysis of the sublingual microcirculation closely matched manual analysis across

121 We hypothesized that organ microcirculation coagulation environment predisposes to

122 l transplantation-induced changes in hepatic microcirculation contributed to transplanted cell cleara

123 We tested whether the chaotic tumor microcirculation could be reconfigured by the mesenchyme

124 To determine whether the regenerated microcirculation could regulate flow, the muscle was sub

125 to treat severe cardiogenic shock patients, microcirculation data in this context are scarce.

126 ecise and potentially powerful tool to treat microcirculation deficits, a common pathology in numerou

127 The microcirculation-derived backward expansion wave is a ne

128 w warranted to better determine the relevant microcirculation determinants during venoarterial extrac

129 RA showed no intestinal microcirculation disturbance compared to sham, but signi

130 organ integrity, systemic inflammation, and microcirculation during hemolysis.

131 Impaired cerebral microcirculation during sepsis is associated with progre

132 Inability to rapidly restore microcirculation during the first 24 hours, despite norm

133 d to increased compression of the intramural microcirculation, especially at the subendocardium.

134 The microcirculation exemplifies the mesoscale in physiologi

135 In the sublingual microcirculation, exposure to hypoxia resulted in an inc

136 Despite robust neovascularization, the microcirculation formed by regenerative angiogenesis in

137 Arterioles in the cutaneous microcirculation frequently display an oscillatory pheno

138 Transfection of the microcirculation guided by a targeted, acoustically-acti

139 Thrombus formation in the cerebral microcirculation has been proposed to contribute to seco

140 Thus, islet microcirculation has no relation to islet cytoarchitectu

141 mechanism of IL2-induced disruption of brain microcirculation has not been determined previously.

142 is a frequent condition that involves renal microcirculation impairment, infiltration of inflammator

143 Natural killer (NK) cells localize in the microcirculation in antibody-mediated rejection (AMR) an

144 ncerning cardiac physiology and the coronary microcirculation in aortic stenosis and their impact on

145 ital microscopy of inflamed cremaster muscle microcirculation in bone marrow chimera mice.

146 ulation requires adequate functioning of the microcirculation in both organs, with loss of microvascu

147 A healthy, functional microcirculation in combination with nonobstructed epica

148 Our goal was to characterize the sublingual microcirculation in healthy volunteers and patients with

149 the effect of RBC transfusion on sublingual microcirculation in hemorrhagic shock patients.

150 The precise manipulation of microcirculation in mice can facilitate mechanistic stud

151 Using intravital analysis of the islet microcirculation in mice, we found that islet capillarie

152 Here, by directly imaging the lung microcirculation in mice, we show that a large number of

153 estigate the effect of CKD on the myocardial microcirculation in patients referred for clinical (82)R

154 ay represent the earliest changes in retinal microcirculation in patients with mild hypertension, bef

155 ss the vasodilatory capacity of the coronary microcirculation in patients with NSTEMI when compared w

156 impact on macrocirculatory hemodynamics and microcirculation in patients with refractory cardiogenic

157 mization, inhaled nitric oxide would improve microcirculation in patients with sepsis and that improv

158 The main characteristics of sublingual microcirculation in patients with septic shock are hypop

159 solutions on liver and intestine injury and microcirculation in septic rodents.

160 chitecture and function of the reconstructed microcirculation in skeletal muscle.

161 general nonelectroneutral model to study the microcirculation in the lens of the eye.

162 ysm, but how leaked hemoglobin regulates the microcirculation in the pathophysiology of early brain i

163 ty and 2) indicate the important role of the microcirculation in the regenerative capacity of a muscl

164 s currently available to assess the coronary microcirculation in the setting of ST-segment-elevation

165 was to assess the time course of sublingual microcirculation in traumatic hemorrhagic shock during t

166 Alterations of microcirculation in traumatic hemorrhagic shock patients

167 ng novel in vitro microfluidic models of the microcirculation, including 1 capable of deoxygenating t

168 clusion, lower capillary density of the skin microcirculation independently associated with albuminur

169 RBC transfusion improves sublingual microcirculation independently of macrocirculation and t

170 Microcirculation inflammation (MCI = g + ptc score) was

171 c antibodies (dnDSA) we studied the value of microcirculation inflammation (MI; defined by the additi

172 of natural killer markers were correlated to microcirculation inflammation and graft outcomes to a gr

173 because both groups had a similar degree of microcirculation inflammation and peritubular capillary

174 4d deposition, transplant glomerulopathy, or microcirculation inflammation had a 100.0% graft surviva

175 as observed between patients with or without microcirculation inflammation in contrast to previous re

176 Microcirculation inflammation was prevalent, with glomer

177 rterial pressure, transplant glomerulopathy, microcirculation inflammation, and de novo/recurrent glo

178 renal transplant patients with de novo DSA, microcirculation inflammation, defined by g + ptc, assoc

179 There was, however, no change in microcirculation inflammation, gene expression patterns,

180 Microcirculation inflammation, particularly glomerulitis

181 ced C4d staining in peritubular capillaries, microcirculation inflammation, splenic plasma cells, cir

182 ) recurrent biopsies showing the presence of microcirculation inflammation.

183 orter time to rejection (P<0.001), increased microcirculation injury (P=0.002), and C4d capillary dep

184 pecificity of prediction of TG compared with microcirculation injury score alone.

185 d to widely accepted notions regarding islet microcirculation, intra-islet signaling, and islet devel

186 A new model of islet microcirculation is built on the basis of analyses of in

187 estration of parasitized erythrocytes in the microcirculation is considered the central pathophysiolo

188 6C(low)) patrolling along the vessels of the microcirculation is critical for endothelial homeostasis

189 wever, the role of this pathway in the brain microcirculation is not known.

190 The vasodilatory capacity of the microcirculation is preserved in selected patients with

191 The microcirculation is responsible for orchestrating adjust

192 Microcirculation is severely impaired in patients with r

193 se network attributes exist in a regenerated microcirculation is unknown, and methodologies for answe

194 RIPC repeated over several days on the human microcirculation is unknown.

195 Reflecting an improved microcirculation, lactate levels normalized within 24 ho

196 excessive pulsatile energy into the cerebral microcirculation, leading to microvascular damage and im

197 rterial blood flow, while disturbance of the microcirculation leads to long-term impairment of muscle

198 The scores correlated with the presence of microcirculation lesions and donor-specific antibody.

199 psies from 315 patients, based on histology (microcirculation lesions) and donor-specific HLA antibod

200 PAH, which would account for skeletal muscle microcirculation loss and exercise intolerance.

201 ce in PAH is associated with skeletal muscle microcirculation loss and impaired angiogenesis secondar

202 cise capacity ([Formula: see text]o2max) and microcirculation loss on quadriceps muscle biopsy (in CD

203 e suggested that changes in peripheral nerve microcirculation may contribute to nerve damage in diabe

204 trance of bioactive oxidized lipids into the microcirculation may mediate adverse clinical outcomes d

205 e indicates that alterations of the cerebral microcirculation may play a role in Alzheimer disease, t

206 Alterations in the macrocirculation and microcirculation may represent early clinical manifestat

207 ime points and included visualization of the microcirculation, measurement of tissue oxygenation, and

208 r the routine use of quantitative sublingual microcirculation measurements at the point-of-care.

209 membrane oxygenation and for whom sublingual microcirculation measurements before cannulation were po

210 Heparanase has a role in regulating the microcirculation milieu.

211 crofluidic optical stretcher, a microfluidic microcirculation mimetic, and real-time deformability cy

212 ecisely organized and exquisitely responsive microcirculation must form.

213 neous circulation improved postresuscitation microcirculation, myocardial and cerebral functions, and

214 ignificantly better postresuscitation tissue microcirculation, myocardial ejection fraction, and neur

215 tized and intestinal (n = 6/group) and liver microcirculation (n = 6/group) were obtained using intra

216 estration of parasitized erythrocytes in the microcirculation, not from hypovolemia.

217 osed, all based on the assumption that islet microcirculation occurs in an enclosed structure.

218 formation, i.e. conditions that exist in the microcirculation of active skeletal muscle.

219 o assess the effects on macrocirculation and microcirculation of adding an intra-aortic balloon pump

220 of the isolated retina and in the cremaster microcirculation of anesthetized mice.

221 d after ischemia-reperfusion in the coronary microcirculation of angptl4-deficient mice.

222 The specialized tightly controlled microcirculation of craniofacial neurosensory organs is

223 These findings demonstrate that the microcirculation of healthy aged skin can further dilate

224 mmatory phenotype in the VAT but not the SAT microcirculation of lean wild-type mice.

225 The microcirculation of septic patients has been characteriz

226 xercise, vasodilatation initiated within the microcirculation of skeletal muscle ascends the resistan

227 inhibitor (TFPI), and TFPI-2 were low in the microcirculation of the liver, lung, brain cortex, and b

228 , red blood cell zinc protoporphyrin, in the microcirculation of the lower lip.

229 way, much has been learned about the unique microcirculation of the lung, including immune cell migr

230 Understanding the differences in vascular microcirculation of the peripapillary retinal nerve fibe

231 To investigate the changes in the microcirculation of the peripapillary RNFL of eyes with

232 l vasculature, including those affecting the microcirculation of the subcortical white matter, are ke

233 ung, brain cortex, and bone, and high in the microcirculation of the subcutis, skeletal muscle, brain

234 The cremasteric microcirculation of wild-type (C57BL/6), Gal-3(-/-), and

235 nnections between PVAT and the distal muscle microcirculation, or adipomuscular arterioles, the remov

236 Profound microcirculation parameter changes found before venoarte

237 echocardiography, arterial blood gases, and microcirculation parameters did not differ between patie

238 Evaluation of microcirculation perfusion is critical for optimization

239 data suggest that the status of the coronary microcirculation plays a role in determining susceptibil

240 nctional and structural abnormalities of the microcirculation plays an important role in systemic scl

241 dark-field videomicroscopy of the sublingual microcirculation prior to and 2 hours after study drug i

242 Thus, mPGES-1, a key microcirculation protector, constrains MI/R injury and t

243 Hepatic damage, microcirculation, regeneration, and vascular remodeling

244 The endothelium of the microcirculation regulates both the transport of lipids

245 How APOE genotype affects brain microcirculation remains elusive.

246 We hypothesized that the VAT and SAT microcirculations respond differently to postprandial pr

247 albuminuria, measurements of skin and muscle microcirculation, retinal arteriolar and venular diamete

248 dependent relation after adjusting for total microcirculation scores.

249 al microscopy studies of the mouse cremaster microcirculation showed that tumor necrosis factor-alpha

250 TEMI when compared with a model of preserved microcirculation (stable angina [SA] cohort: culprit and

251 magnetic carriers in blood vessels and tumor microcirculation still remains unclear.

252 me subsumes myocardial dysfunction, impaired microcirculation, systemic inflammatory response, and ne

253 as of incomplete clearance of blood from the microcirculation that did not clear after a further atte

254 wever, there are unique aspects of the human microcirculation that serve as the focus of this review.

255 icrosurgical removal of PVAT from the muscle microcirculation, that local PVAT depots regulate insuli

256 ession of collaterals, the assessment of the microcirculation, the impact of collateral steal as well

257 insulin-induced vasoreactivity in the muscle microcirculation through secretion of adiponectin and su

258 um-b-value regimens as a surrogate marker of microcirculation, to study its correlation with dynamic

259 n these mice with metastasis, liver and lung microcirculation turned to express high levels of coagul

260 (H2O2) regulates vascular tone in the human microcirculation under physiological and pathophysiologi

261 pts the blood-brain barrier and alters brain microcirculation, underlying vascular leak syndrome that

262 servational study to evaluate the sublingual microcirculation using side-stream dark-field imaging in

263 e simulate deformable red blood cells in the microcirculation using the immersed boundary method with

264 ulmonary artery pressures but did not affect microcirculation variables in cardiogenic shock patients

265 d that the SVF cells would form a functional microcirculation via vascular assembly and inosculation

266 Pulmonary microcirculation was analyzed at 0 hr and 2 hrs using in

267 usive reactive hyperaemia (PORH) in the skin microcirculation was assessed by laser Doppler flowmetry

268 The sublingual microcirculation was assessed with a Sidestream Dark Fie

269 Reduced RNFL microcirculation was detected in the normal hemisphere o

270 The sublingual microcirculation was estimated at the study inclusion af

271 The sublingual microcirculation was evaluated by means of sidestream da

272 ndard hemodynamic assessment, the sublingual microcirculation was evaluated using sidestream dark-fie

273 Compared with normal eyes, reduced RNFL microcirculation was found in the normal hemisphere of e

274 Sublingual microcirculation was impaired for 72 hours despite resto

275 tion of the macrocirculation, the sublingual microcirculation was impaired for at least 72 hours.

276 The RNFL microcirculation was measured within an annulus region c

277 Microcirculation was not altered by the increased number

278 In the control group, no microcirculation was observed after 6 hours of cold stor

279 In addition, the sublingual microcirculation was observed using sidestream dark-fiel

280 DCT) values were determined; contribution of microcirculation was quantified in perfusion fraction (F

281 ts with severe sepsis in whom the sublingual microcirculation was visualized using orthogonal polariz

282 Since inflammation is known to modulate the microcirculation, we investigated the hypothesis that ch

283 servational study where macrocirculation and microcirculation were assessed with clinical-, Doppler e

284 d side-stream dark-field-assessed sublingual microcirculation were unchanged by stopping and restarti

285 RA exhibited no derangements in liver microcirculation when compared to sham and HES.

286 usion revealed best results in mortality and microcirculation, when compared with colloid infusion.

287 As in the microcirculation, where previous studies have been perfo

288 , megakaryocytes extend projections into the microcirculation, where shear facilitates fragmentation

289 y with IVFs affects sRBC biomechanics in the microcirculation, where vaso-occlusion takes place.

290 s of heparanase, TF, TFPI, and TFPI-2 in the microcirculation, which enables tumor cell retention.

291 to the nucleus is not dependent on the lens microcirculation, which is believed to be responsible fo

292 on leads to concomitant hypoxia from loss of microcirculation, which serves as a critical factor lead

293 ial dysfunction, which further impairs local microcirculation with a feed-forward loop of organ damag

294 pacity to reconcile barrier phenotype of the microcirculation with an angiogenic cascade is not known

295 t the relative contribution of a compromised microcirculation with disease, in isolation of co-morbid

296 significant reduction of liver and intestine microcirculation with severe side effects on coagulation

297 col describes an in vitro model of the human microcirculation with the potential to recapitulate disc

298 , noninvasive techniques for measuring human microcirculation, with a focus on methods, interpretatio

299 esized that the vasodilatory response of the microcirculation would be preserved in NSTEMI.

300 on in patients with sepsis and that improved microcirculation would improve lactate clearance and mul