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1 mouse strain that expresses En1 in the Dbx1 microdomain.
2 nstrates that the D(E)RY motif is a hydrated microdomain.
3 he conserved and variable sequons in the HMP microdomain.
4 s, facilitating PIP(2) concentration in this microdomain.
5 changes in the lipid composition of membrane microdomains.
6 ed protein 35 (VPS-35) did not affect HGRS-1 microdomains.
7 organ that is made up of distinct layers and microdomains.
8 e sites for HG crosslinking within cell wall microdomains.
9 iate with sphingolipid- and cholesterol-rich microdomains.
10 of heterotypic signaling networks underlying microdomains.
11 ic mechanisms operate in submillimeter-scale microdomains.
12 rotenoids play a role in organizing membrane microdomains.
13 the TGN Ca(2+) pump (SPCA1) in specific TGN microdomains.
14 s mechanisms that establish subcellular cAMP microdomains.
15 exclusively from plasma membrane-disordered microdomains.
16 pendent endocytosis via tetraspanin-enriched microdomains.
17 ions of signaling enzymes within subcellular microdomains.
18 actin/sorting nexin/retromer tubular (ASRT) microdomains.
19 referentially colocalize with fluid membrane microdomains.
20 ers that separate the antigenically variable microdomains.
21 CYP1A1 had less affinity to bind to ordered microdomains.
22 of the cAMP pathway components in signaling microdomains.
23 incorporation of CXCR4 receptors into these microdomains.
24 mentalized signaling in discrete subcellular microdomains.
25 AT localization in cholesterol rich membrane microdomains.
26 holipase D2 (PLD2) in caveolin-rich membrane microdomains.
27 antiviral signaling through lipid raft-like microdomains.
28 the K-Ras4B membrane binding domain in rigid microdomains.
29 r robust replication in PE-enriched membrane microdomains.
30 es recruitment of KIT to caveolin-1-enriched microdomains.
31 and limits binding of PKA to local sarcomere microdomains.
32 evealing hyperintense signal in synapse-rich microdomains.
33 ht be most effective when localized to these microdomains.
34 diffusion coefficient within the cylindrical microdomains.
35 ntaining Beclin1 and Bif-1 to the lipid raft microdomains.
36 suggesting budding from specialized membrane microdomains.
37 esting that the virus assembles at PIP2-rich microdomains.
38 proper docking of LPS in lipid raft membrane microdomains.
39 and colocalization of RhoB to these membrane microdomains.
40 motes their association with plasma membrane microdomains.
41 horing proteins in organizing these activity microdomains.
42 n associated with glycosphingolipid-enriched microdomains 1 (PAG1) is a transmembrane adaptor protein
43 Furthermore, we captured the formation of PA microdomains accumulating at the membrane cytoplasmic le
44 membrane-anchored GCaMP3 mice, we found that microdomain activity that occurs in the absence of inosi
45 and role of this channel in sensory membrane microdomains, all of which helps to understand the puzzl
46 reminiscent of detergent-insoluble membrane microdomains, although our approach is valuably detergen
47 s exhibited numerous large abnormal membrane microdomains (aMMDs), which trap and inactivate physiolo
48 s with PDZ domain-containing proteins, lipid microdomains and acute trafficking of the transporters v
49 link between RTK-initiated phosphoinositide microdomains and Arf6 during signal transduction and can
51 revealed that AtHIR1 is present in membrane microdomains and co-localizes with the membrane microdom
53 TnT mutation causes dysfunction of sarcomere microdomains and how these events contribute to misalign
55 tor module that targets rPGRP-LC to membrane microdomains and interacts with the negative regulator P
57 MAGUK family, recruits Kv1.3 into lipid-raft microdomains and protects the channel against ubiquitina
59 se II-mediated phosphorylation in non-native microdomains and resulted in an elevated ICa,L window cu
60 Taken together, these findings suggest that microdomains and the cytoskeleton constrain AtHIR1 dynam
61 cle tracking analysis revealed that membrane microdomains and the cytoskeleton, especially microtubul
62 ssed, the formation of plasma membrane lipid microdomains and the number of exocytotic events were de
63 supported by the surface exposure of the HVR microdomains and the slow diffusion-type porin function
65 ecruits the BMP receptor complexes into raft microdomains, and positively modulates signaling possibl
66 ponent optogenetic tools to manipulate ionic microdomains, and probe the complex neuronal-extracellul
67 ray of phosphatidylinositol(4,5)bisphosphate microdomains, and that their constriction was sensitive
68 In particular, mitochondrial lipid raft-like microdomains appear to function as platforms in cell apo
69 ined via general gradient waveforms when the microdomains are characterized by a general diffusion te
70 us degree of complementarity, liquid crystal microdomains are formed via the selective aggregation of
72 hile the mechanistic details of these Ca(2+) microdomains are only beginning to emerge, it is evident
74 cted rates of entry into and escape from the microdomain as well as enhanced phospho-signalling withi
77 ped that accounts for ER-mitochondria Ca(2+) microdomains as the ud compartment (besides the cytosol,
78 ed Incs were localized to inclusion membrane microdomains, as evidenced by colocalization with phosph
79 al neuraminidase inhibitor, disassembled the microdomains, as evidenced by reduced staining of tropho
80 by the major monovalent ions, which occur in microdomains, as global events, or as propagating interc
81 d enriched with high-density regions forming microdomains, as revealed by single particle tracking ex
82 mal coverage and intensity of HGRS-1-labeled microdomains, as well as increased total levels of HGRS-
83 lve a general reorganization of the membrane microdomains associated with virion assembly, but rather
85 oplasmic pole-organizing protein popZ (PopZ) microdomain at the cell pole of the asymmetrically divid
86 mbrane phosphatidylinositol 4,5-bisphosphate microdomains at nascent sheaths, followed by a filamento
87 ssary for the formation of three-dimensional microdomains at the cell poles in Caulobacter crescentus
88 buted to the formation of GM1-enriched lipid microdomains at the exocytotic sites in chromaffin cells
89 oduction of DA neurons derived from the Dbx1 microdomain, at the expense of STN and PM populations.
92 ardiac myocytes to indicate the formation of microdomains between acidic and SR calcium stores, suppo
93 trix proteins in specialized plasma membrane microdomains, but the effects of these interactions on t
94 mW average power) increased the frequency of microdomain Ca(2+) events but left their amplitude, area
98 demonstrate the subtle build-up of aberrant microdomain Ca(2+) transients in the fine astroglial pro
99 r capable of quantitatively predicting local microdomain Ca(2+) transients in the vicinity of VGCCs d
100 es exhibit spontaneous, activity-independent microdomain Ca(2+) transients in their fine processes.
101 local ROS production can activate astrocyte microdomain Ca(2+) transients through TrpML, and that a
103 d into circuits, they exhibit whole-cell and microdomain Ca(2+) transients, which are sensitive to no
104 rary imaging methods fall short of measuring microdomain Ca(2+)-contraction coupling in live cardiac
105 s exhibit spatially-restricted near-membrane microdomain Ca(2+)transients in their fine processes.
106 uptake depends on cholesterol-rich membrane microdomains called lipid rafts, and can be blocked by n
107 ic domain, these two organelles share common microdomains called mitochondria-associated ER membranes
108 dy recycling studies showed that CD63 in WPB microdomains can originate from the plasma membrane.
109 nsporter A1 plays a major role in regulating microdomain cholesterol and is most efficient when lipid
110 comes esterified, CE droplets accumulate and microdomain cholesterol content becomes poorly regulated
111 ch apoproteins relieves the burden of excess microdomain cholesterol in immune cells allowing a reduc
113 ( approximately 90%) demonstrated long-range microdomain connectivity, while the recovery time depend
116 sociated glycoprotein (MAG) require membrane microdomains containing either sulfatides or complex gan
119 oth serum EV-enriched fractions and membrane microdomains containing the acquired MHC alloantigens in
120 maging reveals that Snx14 is recruited to ER microdomains containing the fatty acyl-CoA ligase ACSL3,
122 eometrical constraints, including dead-space microdomains, contribute to the hindrance to diffusion.
123 ii) the structural variation observed in the microdomains corresponded to the mean length of variants
124 In conclusion, our results indicate that microdomain coupling is important for exocytosis in high
125 novel boundary subdividing the mdFP into two microdomains, defined by engrailed 1 (En1) and developin
129 cholestatic rats, BSEP showed a canalicular microdomain distribution similar to that of control rats
131 (hetTECs) with non-fibrous proteoglycan-rich microdomains engineered into the fibrous structure, and
132 ter protein to Pd, likely to plasma membrane microdomains enriched at Pd As such, the GPI modificatio
133 -liquid-disordered phase surrounding ordered microdomains enriched in cholesterol and protein complex
135 the presence of detergent-insoluble membrane microdomains enriched in sterols and sphingolipids.
138 ed processes that form functionally isolated microdomains, facilitating local homeostasis by redistri
139 an unexpected chemodominance of the HA stalk microdomain for small-molecule inhibitors in IAV inhibit
141 We propose that these clusters serve as microdomains for EV signaling and play an important role
143 ytosis, in which they are believed to act as microdomains for protein interactions and intracellular
146 acquired heart failure, acute stress impairs microdomain formation, limiting contractility and promot
148 ationalize the developmental accumulation of microdomain-forming lipids in synapses by proposing a me
149 l rich boundaries of hexagonally packed DPPC microdomains, freely diffuse along the bilayer midplane,
150 sduction within the cell, because lipid-rich microdomains function as assembly points for signaling m
152 dopaminergic (DA) neurons, whereas the Dbx1 microdomain gives rise to subthalamic (STN), premammilla
155 results highlight how STIM1-dependent Ca(2+) microdomains have a major impact on intracellular Ca(2+)
159 l interactions between the closely contacted microdomains improve the mechanical properties of the co
160 approximately <2 kHz) to progressively more microdomain in high-frequency cells ( approximately >2 k
162 enhanced dynamic properties of nuclear lipid microdomains in cancer cells with an increased shuttling
164 P, mostly present in raft (high cholesterol) microdomains in control rats, was largely found in nonra
166 port the quantification of proteoglycan-rich microdomains in developing, ageing and diseased fibrocar
167 knowledge of the development of the sensory microdomains in mammalian skin and the mechanosensory ne
169 FTR and its dynamics both within and outside microdomains in the plasma membrane of primary human bro
171 in and critical organizer of caveolae (small microdomains in the plasma membrane), as a regulator of
172 alk between channel activities within single microdomains in tuning the physiological response of neu
173 alized complementary ESCRT-0 and RME-8/SNX-1 microdomains in vivo and assayed the ability of retromer
174 afts/caveolae and assessed the role of these microdomains in VSMC ROS production and pro-contractile
175 ne complexes (JMCs) in myocytes are critical microdomains, in which excitation-contraction coupling o
176 ne complexes (JMCs) in myocytes are critical microdomains, in which excitation-contraction coupling o
177 ule-based activation of AMPK can restore TnT microdomain interactions, and partially recovers sarcome
179 the cardiomyocyte, the mitochondrial Ca(2+) microdomain is where contraction, energy and death colli
180 lustering of proteins and lipids in distinct microdomains is emerging as an important principle for t
181 may partition into cholesterol-rich membrane microdomains (lipid rafts), its compartmentalization has
186 lico docking predicted compound binding to a microdomain located at the membrane-distal site of the p
192 lation also imparts signalling power; Ca(2+) microdomains near store-operated CRAC channels in the pl
194 tional reorganization of receptor-associated microdomains occurs in early cardiac hypertrophy, affect
198 bution of single LTCCs in different membrane microdomains of nonfailing and failing human and rat ven
200 ory bulb depends on the existence of defined microdomains of pre-determined neural stem cells along t
201 aggregates, but rather are KS-WNK1-dependent microdomains of the DCT cytosol that modulate WNK signal
202 t AtKEA1 and AtKEA2 transporters in specific microdomains of the inner envelope link local osmotic, i
208 rtilaginous tissues, and the impact of these microdomains on endogenous cell responses to physiologic
209 phosphoinositide species PtdIns(4,5)P2 into microdomains on the plasma membrane, analogous to proces
210 or allowed us to resolve minute PKA activity microdomains on the plasma membranes of living cells and
212 n whether this channel localizes in membrane microdomains or whether it interacts with cholesterol.
213 both critical modifications that control the microdomain organization of CD82 as well as the nanoscal
216 It has been controversial at which membrane microdomains PDGFRs reside and how they control such div
217 ut mouse, near-infrared light-induced Ca(2+) microdomains persisted in the small processes, underpinn
218 at cardiolipin molecules segregate into such microdomains, probably conferring a negative curvature t
220 Analysis of membrane-associated and raft microdomain proteins reinforces this possibility and als
221 R activation, reorganization of BIN1-induced microdomains recruits P-RyR into dyads, increasing the c
222 Voltage and charge distributions in cellular microdomains regulate communications, excitability, and
223 rol into multilayers or 3D structures of BCP microdomains remains limited, despite the possible techn
224 y represent unique plasma membrane signaling microdomains required for signaling by certain receptors
225 exocytosis, mediates the formation of lipid microdomains required for the structural and spatial org
227 rdered lipid microdomains, whereas the rigid microdomains restrict the farnesyl group penetration.
229 and waves caused contractions in subcellular microdomains, revealing a previously underappreciated ro
230 of PopZ contributes to the assembly of polar microdomains, revealing a structural basis for complex n
231 veloping a temporally precise means to study microdomain-scale interactions between extracellular pro
233 ubplasmalemmal calcium and hydrogen peroxide microdomain signaling is a fundamental mechanism regulat
234 esicular release, P/Q-type VGCCs act through microdomain signaling to recruit additional release site
235 reveals that microglia have highly distinct microdomain signaling, and that processes specifically r
236 ocate Galpha(s) from lipid rafts to non-raft microdomains, similarly to other antidepressants but wit
241 c compartments, particularly along recycling microdomains such as dendritic spines and presynaptic bo
242 d interpret voltage distribution in cellular microdomains such as synapses, dendritic spine, cilia an
244 ese subunits colocalize to common functional microdomains, such as juxtaparanodes and the somatic mem
245 1 had little to no effect on SNX-1 and RME-8 microdomains, suggesting directionality to the interacti
246 ansporter, localizes specifically to a glial microdomain surrounding AFD receptive ending microvilli,
248 erse activities, we examined plasma membrane microdomains termed eisosomes or membrane compartment of
250 in functional complexes called "tetraspanin microdomains." Tetraspanins, including CD82, play an ess
251 e receptors, enabled the reconstitution of a microdomain that consists of intracellular loops 2 and 3
252 In plants, the plasmodesmal PM is a discrete microdomain that hosts specific receptors and responses.
253 These extended lamellipodia form a signaling microdomain that sequesters and phospho-inactivates the
254 nd surrounding branched actin filaments form microdomains that anchor a three-dimensional desmin inte
255 highly localized spatial and temporal Ca(2+) microdomains that are required for achieving functional
256 TBC1D5 to restrict late endosomal RAB7 into microdomains that are spatially separated from the amino
257 vides details on how some clustered NGS form microdomains that can be identified and tracked across E
259 es are highly organized, containing specific microdomains that facilitate distinct protein and lipid
260 dria-associated membranes (MAMs) are central microdomains that fine-tune bioenergetics by the local t
261 immune evasion by dividing Env into N-glycan microdomains that have a limited number of N-glycan sequ
262 ) contact sites are evolutionarily conserved microdomains that have important roles in specialized me
263 t Ca(2+) signals determine restricted Ca(2+) microdomains that regulate myofilament remodeling and ac
265 study subcellular PDGFR activity at membrane microdomains, this PDGFR biosensor was further targeted
268 l over otherwise unorganized assembly of BCP microdomains to form both long-range and locally complex
270 (2+) diffusive environment near IP3 receptor microdomains to limit IP3 -mediated Ca(2+) signals as pr
272 ts through TrpML, and that a subset of these microdomain transients promotes tracheal filopodial retr
274 exclusive combinations of sequons in the HMP microdomain using the Los Alamos National Laboratory HIV
275 Real-time cAMP measurements in endothelial microdomains using a novel fluorescence resonance energy
276 eta2-adrenergic receptor-associated membrane microdomains using a novel membrane-targeted Forster res
277 ets to the mitochondrial detergent-resistant microdomains via direct interaction with cardiolipin and
279 unctionally distinct ESCRT-0 and SNX-1/RME-8 microdomains was also compromised in the absence of RME-
280 nd can target functional enzymes to membrane microdomains where pathologic APP-processing is thought
281 hannel complexes within specific subcellular microdomains, where physical proximity allows for prompt
282 AT1 is stimulated by sub-plasmalemmal Ca(2+) microdomains, whereas NFAT4 additionally requires Ca(2+)
283 ntaneously inserts into the disordered lipid microdomains, whereas the rigid microdomains restrict th
284 VPS29 and a 12 residue, four-cysteine/Zn(++) microdomain, which we term a Zn-fingernail, two of which
286 platforms might involve sterol-rich membrane microdomains, which are heterogeneous and highly dynamic
287 itate the formation of postsynaptic membrane microdomains, which may serve key roles in the function
288 is evenly distributed at different membrane microdomains, while integrin-mediated signaling events h
289 ic cells is organized into lipid and protein microdomains, whose assembly mechanisms and functions ar
292 lasma membrane, forming tetraspanin-enriched microdomains with one another and other surface molecule
293 ptic membranes and observe remarkably stable microdomains, with the stability of domains increasing w
294 is the targeting of proteins to subcellular microdomains within bacterial cells, particularly to the
296 ster [Ca(2+)]i, creating [Ca(2+)]i signaling microdomains within the cell that are dependent on mitoc
297 cked, cholesterol- and sphingolipid-enriched microdomains within the plasma membrane that play import
299 y produce nanomesh structures of cylindrical microdomains without requiring layer-by-layer alignment
300 ms) remain difficult to analyse in cellular microdomains, yet they can modulate key cellular events