ライフサイエンスコーパス: microfilarial

1 donors were stimulated in vitro with soluble microfilarial Ag (MfAg) from the filarial parasite Brugi

2 with immunologic effects as enriched in the microfilarial and L3 stages.

3 gen-specific IL-5 production, and diminished microfilarial antigen-driven lymphocyte proliferation th

4 ve interleukin-5 (IL-5) and IL-10, increased microfilarial antigen-specific IL-5 production, and dimi

5 individuals were studded with intracellular microfilarial antigens.

6 tervention-naive areas with 30%, 50%, or 70% microfilarial baseline prevalence (representative of hyp

7 ly and positively associated with increasing microfilarial burden (P<.001).

8 ly and positively associated with increasing microfilarial burden (p<0.00001), but not with blindness

9 s combination (IDA) has improved efficacy of microfilarial clearance at 12 months in individually ran

10 with a trend toward more rapid and complete microfilarial clearance in the DEC group.

11 n subjects with loiasis and had no effect on microfilarial clearance, the reduction in AEC appeared t

12 Geometric mean microfilarial concentration decreased from 9.3 to 5.3 pe

13 Twelve patients with loiasis and microfilarial counts <2000 mf/mL were randomized to rece

14 , the 2 subjects with negative assays having microfilarial counts of 1.

15 The model is fitted to microfilarial data from savannah villages of northern Ca

16 erse events in individuals with high Loa loa microfilarial densities (MFD).

17 Individuals with high microfilarial densities (MFDs) of Loa loa are at risk of

18 refore aimed to investigate changes in L loa microfilarial densities during TaNT campaigns run 18 mon

19 investigates the relationship between L. loa microfilarial density (Loa MFD) and the probability of t

20 However, the presence of MF (rho = 0.45) and microfilarial density (rho = 0.44) were significantly co

21 ivermectin distribution because of an L. loa microfilarial density above the risk threshold, and 397

22 was used to identify persons with an L. loa microfilarial density greater than 20,000 microfilariae

23 ivermectin treatment because of a high L loa microfilarial density in 2015, versus 283 (1.5%) individ

24 All those with a L loa microfilarial density of 20 000 microfilariae per mL or

25 r microfilarial positivity (h(2) = 0.74) and microfilarial density traits (h(2) = 0.81).

26 essed in all participants, was whether L loa microfilarial density was above or below the exclusion t

27 L loa microfilarial density was measured at the point of care

28 licable as a point-of-care method for L. loa microfilarial detection and quantification in resource-l

29 re and in 7 subjects with evidence of dermal microfilarial DNA and were compared with responses in 43

30 non-human primates indicated that they were microfilarial- driven.

31 We evaluated Onchocerca volvulus community microfilarial intensity and prevalence in persons aged >

32 n treatment in Ghana has reduced O. volvulus microfilarial intensity and prevalence, but suboptimal r

33 e shown a direct relation between O volvulus microfilarial load and host mortality in a comprehensive

34 Overall, after adjustment for microfilarial load and other variables, female individua

35 but not with blindness after adjustment for microfilarial load and other variables.

36 in both sexes, a direct relationship between microfilarial load and the incidence of blindness.

37 d an association between Onchocerca volvulus microfilarial load in childhood and risk of developing e

38 IL-5-dependent immunity influenced B. malayi microfilarial loads in the blood.

39 iasis has insufficient sensitivity when skin microfilarial (mf) densities are low, such as following

40 directed primarily against the intravascular microfilarial (MF) parasite stage and mediated in part b

41 predict the impact of TaNT on onchocerciasis microfilarial (mf) prevalence.

42 may be prenatal exposure to the blood-borne microfilarial (Mf) stage of the parasite.

43 cific serpin in the blood environment of the microfilarial parasite in protection from human immunity

44 Heritability estimates were high for microfilarial positivity (h(2) = 0.74) and microfilarial

45 We use the EPIONCHO-IBM model to project microfilarial prevalence trends across Togo's five regio

46 f at least one of the following assessments: microfilarial prevalence, nodule prevalence, Ov16 antibo

47 /Kg bid regimens with a more potent block in microfilarial production.

48 tin (standard) dose clears the skin-dwelling microfilarial progeny of adult worms (macrofilariae) and

49 e drugs are predominantly active against the microfilarial progeny of adult worms.

50 Microfilarial protein (MfP) was isolated from the sheath

51 Microfilarial protein appears to be a new ligand of TLR4

52 Microfilarial protein failed to induce inflammation in e

53 itively associated with the village-specific microfilarial rate, mean intensity of microfilaremia, an

54 nal regression modeling to estimate rates of microfilarial repopulation of the skin in a cohort of 21

55 e did not find any clear association between microfilarial repopulation rate and the number of years

56 mectin-with statistically significantly high microfilarial repopulation rates.

57 predict 14,907 L. loa genes on the basis of microfilarial RNA sequencing.

58 vrrA has 35% identity with the microfilarial sheath protein shp2 of the parasitic worm

59 This response is not dependent on the microfilarial stage of the parasite and is also independ

60 elicit high levels of host IL-4 whereas the microfilarial stage of the parasite induces IFN-gamma pr

61 Despite its abundance in the microfilarial stage, Bm-spn-2 has not been found in any

62 age colony-stimulating factor) to adult- and microfilarial-stage antigens, but not antibody responses