ライフサイエンスコーパス: microsphere

1 face distribution of peptide on the prepared microspheres).

2 nced Raman responses at the interface of ZnO microspheres.

3 capturing the target protein to the polymer microspheres.

4 lex parenteral drug products such as peptide microspheres.

5 but were significantly different for the LA microspheres.

6 which is absent in macrophages challenged by microspheres.

7 ing beads, and radioembolization using (90)Y microspheres.

8 lsion", prior to microencapsulation into the microspheres.

9 IVIVCs) for biodegradable controlled release microspheres.

10 nsed PDMS microdroplets using vacuum-chucked microspheres.

11 of a closely packed lattice of monodispersed microspheres.

12 during release from commonly used polymeric microspheres.

13 d membrane bilayer supported on 3 mum silica microspheres.

14 l solution of small volume to form embryonic microspheres.

15 ow it causes drug release from biodegradable microspheres.

16 measured by direct analysis of the recovered microspheres.

17 gy is the Luminex MagPix platform using xMAP microspheres.

18 ce was performed with 300-500-mum Embosphere microspheres.

19 ive hydrogel carrier and drug-loaded polymer microspheres.

20 the organic solvent and harden the embryonic microspheres.

21 e CCL22, referred to here as Treg-recruiting microspheres.

22 hest payload was 0.56(+/-0.01) mumol SNAP/mg microspheres.

23 ere controlled by the bioerosion of the PLGA microspheres.

24 ng domain, and nucleoprotein were coupled to microspheres.

25 PAE was performed with 100-500-mum embolic microspheres.

26 sed a change in the levitation height of the microspheres.

27 acid-polyethylene glycol (PLGA_PEG) polymer microspheres.

28 al properties and in vivo performance of the microspheres.

29 s was performed using 300- to 500-um embolic microspheres.

30 extravasation, as visualized by fluorescent microspheres.

31 ro-in vivo correlations (IVIVCs) for peptide microspheres.

32 timate anatomical shunt measured using 25-um microspheres.

33 e obtained with the standard method and with microspheres.

34 terial cells and carbon nanodots in alginate microspheres.

35 ounts, and separately by appearance of 25-um microspheres.

36 associated with anatomical shunt measured by microspheres.

37 t from gas exchange shunt measured by MIGET (microspheres: 2.3 +/- 7.4%; MIGET: 2.6 +/- 6.1%, P = 0.6

38 ary branch of the left ECA using Embozene(R) Microspheres - 250 mum in size before endoscopic tumour

39 lver-coated Poly(methyl methacrylate) (PMMA) microspheres (50 mum diameter) into tailored patterns.

40 exists for the treatment of CRLM with resin microsphere (90)Y radioembolization.

41 The posttreatment (166)Ho-microsphere activity distributions were estimated with q

42 A single subcutaneous microsphere administration followed by organ harvest one

43 the calcite-solution interface with a silica microsphere and to measure Derjaguin-Landau-Verwey-Overb

44 nanomaterials, carbon nano tubes, polymers, microspheres and biomaterials have been evoked.

45 ncy, we measured anatomical shunt with 25-um microspheres and compared the results to contrast echoca

46 article-decorated synthesis of porous carbon microspheres and could be further applied to synthesize

47 that the microgels form a corona around the microspheres and induce a soft repulsive shoulder that g

48 FM cantilevers were functionalized with PMMA microspheres and probed against C. albicans cells immobi

49 avitreal injections of spironolactone-loaded microspheres and systemic delivery lead to similar reduc

50 ria were labeled with the immune fluorescent microspheres and the fluorescent bacteria were formed.

51 e characteristics of the prepared naltrexone microspheres and the reference-listed drug (Vivitrol(R))

52 ted a new algorithm for AA able to recognize microspheres and to analyze the attached capillary-like

53 combination of a single dose each of plastic microspheres and vascular endothelial growth factor rece

54 ared genotypes using sequencing, fluorescent microsphere, and quantitative polymerase chain reaction

55 ew types of surface modified barium alginate microspheres, and evaluated their inflammatory propertie

56 f molecules including dextran, streptavidin, microspheres, and lentivirus particles.

57 agents including metallic coils, calibrated microspheres, and liquids are available for clinical pra

58 MPs (polyethylene (PE) and polystyrene (PS) microspheres, and polyester (PEST) fibers).

59 es on the quality and performance of peptide microspheres; and 2) to investigate the feasibility of d

60 release of leuprolide from acid-capped PLGA microspheres appeared to be controlled initially by eros

61 The microspheres are attached to cell-free nanofibrous polym

62 Indeed, data suggest that Treg-recruiting microspheres are capable of overcoming the immunological

63 Hence, the microspheres are considered promising as an additive to

64 vior of direct ink write structures, polymer microspheres are good candidates for shape memory elasto

65 n this work, Li3V2(PO4)3@carbon hierarchical microspheres are prepared by a solvothermal reaction and

66 Alginate nano/microspheres are produced by emulsification/internal gel

67 In conclusion, we demonstrate that polymeric microspheres are suitable as drug delivery system for th

68 clusion, this study shows that our polymeric microspheres are suitable as sustained release formulati

69 ular, three-dimensional array of transparent microspheres arranged like the atoms in a diamond crysta

70 r field optical properties of self-assembled microsphere arrays when exposed to an incoherent light s

71 g analysis of gold nanoparticle-loaded latex microspheres as a signal-amplified hybridization tag, wh

72 The method includes the use of polymeric microspheres as mobile assay surfaces and magnetic nanop

73 izing single DNA molecules stretched between microspheres at various heights.

74 developed IVIVCs for two different types of microsphere-based drug products.

75 Enzyme-linked immunosorbent assay and microsphere-based flow cytometric assay were used to ver

76 We present a microsphere-based flow cytometry assay that quantifies t

77 re used for the detection of these toxins: a microsphere-based immunoassay that offered an estimation

78 present study, a Thermogel, Extended-release Microsphere-based-delivery to the Paranasal Sinuses (TEM

79 ability of in vitro release tests to predict microsphere behavior in vivo and develop more meaningful

80 dissociation of single bonds formed between microsphere-bound CD16 antigens and surface-bound anti-C

81 rst release were similar for the risperidone microspheres but were significantly different for the LA

82 s were first deposited on monodisperse Fe3O4 microspheres by a sol-gel method.

83 ifferences (bi-phasic vs tri-phasic) between microspheres can affect the development and predictabili

84 The morphology and sizes of MCP microspheres can be easily controlled by a dual-surfacta

85 er saturated nanocellulose cellulose aerogel microspheres can be easily removed by filtration or cent

86 s can be squeezed and washed out and aerogel microspheres can be reused.

87 which the spatio-temporal data generated by microspheres can be used to infer kinetic parameters ass

88 view board approval is required before glass microspheres can be used under a compassionate-use or re

89 Because nonuniform AD deposition by microspheres cannot be determined by PET at a microscopi

90 Whole Wolbachia or microspheres coated with a synthetic Wolbachia lipopepti

91 erence in the magnetic properties of polymer microspheres compared to those without protein.

92 pregulated on activated myofibroblasts, into microspheres composed of hydrophilic multi-block copolym

93 measurements of the 2% SPIO-labeled yttrium microsphere concentration were well correlated with know

94 As representation of blood cells, the microsphere concentrations may provide useful informatio

95 dictability of IVIVCs for complex parenteral microspheres containing a variety of therapeutic molecul

96 vel A IVIVC can be established for polymeric microspheres containing another small molecule drug with

97 been established and validated for polymeric microspheres containing risperidone (a practically water

98 nses over the study period compared to blank microsphere control CGM implants.

99 Silica microspheres covalently coupled with a high density of r

100 ically single down-shifting and upconversion microspheres, crystalline microplates, and color-barcode

101 ars) underwent TACE with doxorubicin-eluting microspheres (DEB) (hereafter, DEB-TACE) and subsequentl

102 The prepared porous carbon microspheres decorated with gold-nanoparticle had a 3D h

103 A chitosan-based microsphere delivery system has been fabricated for cont

104 ased measurements of 2% SPIO-labeled yttrium microsphere delivery were well correlated with infused d

105 embolization, increasing the specificity of microsphere delivery, and reducing the lung-shunt fracti

106 An analysis of microsphere deposition patterns within the gastrointesti

107 was superficial to areas of abnormally high microsphere deposition.

108 is, were offered variously sized polystyrene microspheres (diameters 19-1000 mum) and nylon microfibe

109 nal capillary rarefaction there was an acute microsphere dose-dependent reduction in muscle fatigue r

110 e carbon layer on the surface of Li3V2(PO4)3 microspheres during the annealing process.

111 rpose To assess the visibility of radiopaque microspheres during transarterial embolization (TAE) in

112 Administration of Treg-recruiting microspheres effectively mitigated the symptoms of DED a

113 ks from poly(lactic-co-glycolic acid) (PLGA) microspheres embedded in a poly(N-isopropylacrylamide) (

114 ytes are composed of silica nanoparticles in microspheres embedded in gelatin, both are low refractiv

115 atches, in situ forming injectable implants, microspheres embedded in implants and IVRs addressing mu

116 ulites are similar to the synthetic vaterite microspheres employed in laser trapping applications.

117 ng capacity and high selectivity of the MMIP microspheres enabled efficient extraction of cloxacillin

118 duction in TGF-beta expression, thus, a PLGA microsphere encapsulating PD-1 antagonist peptides A12 (

119 radable poly(lactic-co-glycolic acid) (PLGA) microspheres encapsulating a model luteinizing hormone-r

120 Thus, EZ growth, confirmed by microsphere exclusion and UV-VIS absorbance spectroscopy

121 The prepared microspheres exhibited differences in critical physicoch

122 BV and the reference standard of fluorescent microspheres (FMS) for measurement of renal perfusion in

123 uiding tool in development of new generation microspheres for cell encapsulation therapy.

124 ically feasible process to produce polymeric microspheres for sustained-release delivery of protein d

125 ully developed in a rabbit model for peptide microspheres for the first time.

126 lso showed that all the drug-loaded PLGA-PEG microspheres for the localized and targeted treatment of

127 refore, we developed biodegradable polymeric microspheres for the sustained release of proteinaceous

128 reatment of neuroendocrine tumours and (90)Y-microspheres for the treatment of hepatic tumours.

129 re, two poly(lactic-co-glycolic acid) (PLGA) microsphere formulations encapsulating the model steroid

130 Both microsphere formulations exhibited erosion-controlled re

131 imized to prepare commercially relevant PLGA microsphere formulations for delivery of peptides, inclu

132 0-dimensional metallic microspheres generate light-emitting filaments that are

133 he efficacy of a long-term, non-invasive gel/microsphere (GMS) eye drop for glaucoma.

134 olization of liver malignancies with (166)Ho-microspheres has been shown to be safe in a phase 1 dose

135 rrelations (IVIVCs) for parenteral polymeric microspheres has been very challenging, due to their com

136 Because glass microspheres have a higher activity per particle, they c

137 Because resin microspheres have a lower activity per particle, more pa

138 In addition, resin microspheres have been approved by the U.S. Food and Dru

139 (166)Ho-microspheres have recently been approved for clinical us

140 Cell-laden hydrogel microspheres have shown encouraging outcomes in the fiel

141 A fluorescent microsphere hybridization assay was designed that was ca

142 ent and evaluation of a multiplexed magnetic microsphere immunoassay (MMIA) to simultaneously detect

143 is feasible to develop and use a multiplexed microsphere immunoassay as a next generation screening t

144 using a recombinant antigen-based SGERPAxMap microsphere immunoassay, and some of them were further e

145 unosorbent assay (ELISA) and a Luminex-based microsphere immunoassay.

146 efractory CRLM were treated with resin (90)Y-microspheres in a prospective phase II clinical trial.

147 ide (DCM) was spray-dried before washing the microspheres in cold ddH(2)O and freeze-drying.

148 of periodically driven and optically tweezed microspheres in fluid and find a rich variety of dynamic

149 e motion of negatively charged, carboxylated microspheres in mucus from pregnant patients was signifi

150 hemotherapy with SIRT using yttrium-90 resin microspheres in patients with metastatic colorectal canc

151 icting the in vivo performance of naltrexone microspheres in the investigated animal model.

152 tifibrotic efficacy of pPB-MSA-Y27632-loaded microspheres in the Mdr2-/- mouse model of progressive b

153 We study the phase behavior of microspheres in the presence of poly(N-isopropylacrylami

154 l moving blood volume (FMBV) and fluorescent microspheres indicates that 3D FMBV shows excellent corr

155 Radioembolization with (166)Ho-microspheres induced a tumor response with an acceptable

156 e developed a novel protocol in rats whereby microspheres injected into the femoral artery allowed a

157 udies, (13)NH(3) injections were paired with microsphere injections.

158 ication immobilized on alkali-treated silica microspheres, interrogated with a dedicated fiber-optic

159 uperfusion) would decrease blood flow (15 um microspheres), interstitial space oxygen pressures (PO(2

160 l injection of radioactive yttrium-90-loaded microspheres is increasingly used for the treatment of p

161 ce between naltrexone and risperidone loaded microspheres is their respective bi-phasic and tri-phasi

162 ociated electrical signatures and had a 7 um microsphere limit of detection.

163 y means of a combination of a cost-effective microsphere lithography technique and subsequent dry/wet

164 Such arrays are typically used for microsphere lithography where each sphere acts as a ball

165 d to incorporate the chitosan/hydroxyapatite microspheres-loaded with AL (CH/nHA-AL) into poly(L-lact

166 omated high-throughput platform based on the microsphere Luminex technology that measures antibodies

167 The in vivo release of Tr-A from microspheres made of a higher molecular weight, ester en

168 l was to determine what effect the number of microspheres may have, if any, on tumor control in (90)Y

169 Positron emission tomography and microsphere MBF measurements correlated closely.

170 eep temporal artery as a potential route for microspheres migration.

171 posed using functionalised modified magnetic microspheres (MMSs) to "amplify" the effect of target bi

172 In the microsphere model, PD-1 ligands are up-regulated by infe

173 olymer interaction, in vitro degradation and microsphere morphology studies were conducted to facilit

174 escribe the development of multi-loaded PLGA-microspheres (MSs) incorporating three recognised neurop

175 -Ab via poly(lactic-co-glycolic) acid (PLGA) microspheres (MSs) was compared at experimentally-create

176 Neither microspheres nor natural sediments altered the crab's re

177 mbined utilization of PDMS microdroplets and microspheres not only enables the realization of microsp

178 ume histogram also decreased with decreasing microsphere-number density in all tumors.

179 Differences in microsphere-number density may have an effect on microsc

180 in vitro release profiles of the naltrexone microspheres obtained using USP apparatus 4.

181 ucting CaO2 core-mesoporous shell-CaO2 shell microspheres (OCRMs).

182 comparing single intravitreal injections of microspheres of DMQ-MSs to their equivalent individual s

183 The microspheres of lyophilized tiger nut milk were spherica

184 , quality of life, and quantification of the microspheres on SPECT and MRI.

185 tched saline; PE and SU groups received only microspheres or SU5416, respectively.

186 be used to induce rapid NO release from the microspheres over several hours.

187 ons between the polycations and the hydrogel microspheres over time in vitro.

188 lves the perfusion of molecular probe-coated microspheres over tissues.

189 study, poly(dopamine-quinone chromium (III))-microspheres (PDQCM) were used for the modification of g

190 th factor receptor antagonist in polystyrene microspheres (PE) + tyrosine kinase inhibitor SU5416 (SU

191 combined were related to reference standard microsphere perfusion measurements (PMICRO), as follows:

192 oronary arteries combined were compared with microsphere perfusion measurements by using regression,

193 most identically sized dye-doped polystyrene microspheres placed on adjacent holes at the tip of a mi

194 ivo drug release from conjugated drug-loaded microspheres (PLGA-PEG_PGS-LHRH, PLGA-PEG_PTX-LHRH) is s

195 Polyaniline hollow microsphere (PNHM)/Fe(3)O(4) magnetic nanocomposites hav

196 ere, we incorporate two different gas filled microsphere pore formers to evaluate the effect of shell

197 We found that signals based on adhered microsphere position and relative orientation were evalu

198 itionally equivalent leuprolide acetate (LA) microspheres prepared with minor manufacturing changes (

199 crospheres, some of the in-house spray-dried microspheres presented highly similar or even improved l

200 Peptide loaded PLGA microsphere products are more complex in terms of manufa

201 anism compared to small molecule loaded PLGA microsphere products.

202 noparticles were attached onto the resulting microsphere-protein complex, creating a significant diff

203 ensional colloidal crystals of submicrometer microspheres provide a convenient model solid system in

204 h the capture antibodies and the polystyrene microspheres (PSs) modified with the detection antibodie

205 cy, and prognostic factors for (90)Y-yttrium microsphere radioembolization of unresectable liver meta

206 We embedded resonant polar dielectric microspheres randomly in a polymeric matrix, resulting i

207 shunt was quantified by the number of 25-um microspheres recovered in systemic arterial blood.

208 Motion of the microsphere reflected underlying forces exerted by the m

209 For both species, the proportion of microspheres rejected increased from ca. 10-30% for the

210 and therefore, any unintended change in the microsphere release profile may lead to undesirable side

211 ver fibrosis how the subcutaneously injected microspheres released pPB-HSA into both plasma and fibro

212 There are 2 types of (90)Y microspheres: resin and glass.

213 ing for free fluid and cellular exchange and microsphere retrieval during release.

214 Comparison between resin and glass microspheres revealed higher but not statistically signi

215 Comparison between resin and glass microspheres revealed no significant survival difference

216 apatite (PLLA/nHA) matrix to prepare a novel microspheres-scaffold hybrid system (CM-ALs) for drug de

217 A microspheres-scaffold-based release system containing AL

218 (90)Y-microsphere selective internal radiation therapy (SIRT)

219 Molecularly imprinted porous polymer microspheres selective to Alternaria mycotoxins, alterna

220 ivering a calculated lobar activity of (90)Y microspheres selectively to treat a tumor involving 1 or

221 sensor arrays based on Pd(II)-silica porous microsphere sensors and their application as an optoelec

222 The obtained rhGM-CSF microspheres showed a satisfied release profile with the

223 boxyfluorescein covalently coupled to silica microspheres shows an inverse shift in fluorescence in r

224 ne contrast bubble score was associated with microsphere shunt (rho = 0.60, P < 0.001).

225 Compared with the commercial LD microspheres, some of the in-house spray-dried microsphe

226 With this instrument format and fluorescent microsphere standards, we obtain analysis rates of 100K/

227 Although the microspheres still contained protein at day seven, pPB-H

228 By contrast, the higher Tg microsphere structures exhibit reduced compression set w

229 The lower Tg microsphere structures exhibit substantial compression s

230 s the formation of various types of alginate microspheres such as core-shell, Janus, and particle mix

231 ded poly(D,L-lactic-co-glycolic acid) (PLGA) microspheres (Sunb-malate MS) with a particle size of ap

232 scribed centrifugal forces can be applied to microsphere-tethered biomolecules.

233 through degradable polymer microspheres (TRI microspheres; TGF-beta1, Rapamycin (Rapa), and IL-2).

234 present a type of ordered mesoporous TiO(2) microspheres that combines radially aligned mesostructur

235 Specifically, microspheres that exhibit an initial burst release phase

236 mum) carboxylate-modified polystyrene latex microspheres that represented virus- to protozoa-sized p

237 The aerogel microspheres that were saturated with stripping solution

238 er optimizing the alginate concentration for microspheres, the combined osteogenic and mineralization

239 ng pPB-MSA-Y27632 in biodegradable polymeric microspheres, thereby reducing short-lasting peak concen

240 Glass microspheres thus may be more suitable when early stasis

241 Resin microspheres thus may be preferable for larger tumors an

242 ospheres not only enables the realization of microsphere-tipped PDMS micropillars on non-flat, highly

243 us of living Toxoplasma gondii by adhering a microsphere to the surface of an immobilized parasite.

244 ncy, we compared anatomical shunt with 25-um microspheres to contrast echocardiography, and gas excha

245 nd torsion balance using highly birefringent microspheres to directly and simultaneously measure the

246 formulate subdermal implants and injectable microspheres to eliminate the need for implant removal a

247 ie et al. showed that this flow causes inert microspheres to infiltrate into tumour spheroids via adv

248 ever, the off-target diversion of yttrium-90 microspheres to tissues other than the tumor may lead to

249 nstructs were immobilized onto dyed magnetic microspheres to which SpyCatcher had been coupled and ch

250 safety and efficacy of highly potent peptide microspheres, to minor manufacturing changes.

251 inducing factors through degradable polymer microspheres (TRI microspheres; TGF-beta1, Rapamycin (Ra

252 act phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into

253 Embozene(R) is a new neuroembolizing microsphere used to reduce intraoperative bleeding for h

254 e cells into hollow mesoporous bio-hydrochar microspheres via hydrothermal carbonization method.

255 A higher proportion of the largest microsphere was rejected compared with the longest micro

256 performance of as-synthesized porous carbon microspheres was exemplified as electrode materials for

257 between 3D FMBV and perfusion measured with microspheres was high for both US machines (r(2) = 0.80

258 Encapsulation yield (%) of resistant starch microspheres was in the range of 43.01-48.46.

259 nditions, anatomical shunt measured by 25-um microspheres was not different from gas exchange shunt m

260 Intra-pulmonary shunt measured by 25-um microspheres was not significantly different from gas ex

261 vival difference between both types of (90)Y microspheres was observed in any subgroups of patients w

262 The repartition of microspheres was studied by angiographic and histologica

263 e system containing AL-encapsulated chitosan microspheres was successfully fabricated in this study.

264 mization) on crosslinking and bioactivity of microspheres was tested.

265 st agent solution (perflutren protein-type A microspheres) was injected via the nephrostomy tube.

266 sing optically manipulated N-cadherin-coated microspheres, we correlated this behavior to a stronger

267 To fabricate such probes, silica microspheres were coated with a nanocrystalline diamond

268 Luminex microspheres were coupled to recombinant antigens of gen

269 s who underwent radioembolization with glass microspheres were imaged with (90)Y PET/CT for voxel-lev

270 The microspheres were incubated at 37 degrees C up to 56days

271 The pharmacokinetics of the naltrexone microspheres were investigated using a rabbit model.

272 Microspheres were modified using proprietary polyallylam

273 Two types of microspheres were prepared with different molecular weig

274 Polypyrrole magnetic microspheres were synthesized and used to extract carbar

275 Molecularly imprinted polymer microspheres were synthesized by precipitation polymeriz

276 MMIP microspheres were synthesized using a core-shell techniq

277 al and thermal properties of the drug-loaded microspheres were then characterized using Fourier Trans

278 10-mum polymer microspheres were used as a biomimetic model where MNPs

279 The hollow microspheres were used as microreactors and carriers for

280 to arise from the contact points between the microspheres which produce paths for light leakage.

281 This study investigated if calcium phosphate microspheres, which have remineralizing properties, coul

282 Assay" (FBA), based on the use of Cytodex 3 microspheres, which promote the growth of 3D capillary-l

283 f the whispering gallery modes (WGMs) of the microspheres while also providing a robust and easy to m

284 Microsphere with tiger nut milk presented a shelf life o

285 Nitrogen-doped multichamber carbon (MCC) microspheres with a refined hierarchical structure are r

286 The synthesis of carbon microspheres with a refined hierarchical structure is st

287 in the volume magnetic susceptibility of the microspheres with a resolution of 4.2 x 10(-8) per 1 mum

288 ately, the combination of controlled release microspheres with a thermoresponsive hydrogel provides f

289 hierarchical carbon-nanotube@silicon@carbon microspheres with both high porosity and extraordinary m

290 The ability to generate microspheres with controlled morphology and unusual stre

291 polymer-to-polymer interactions in alginate microspheres with different coating designs, maintaining

292 onally equivalent formulations of naltrexone microspheres with different release characteristics were

293 been established and validated for polymeric microspheres with different release characteristics.

294 ing to avoid membrane detachment in alginate microspheres with double polycation coatings.

295 tra-light cellulose nanofibril based aerogel microspheres with high porous structure and water storag

296 omplex drug products such as parenteral PLGA microspheres with multiphasic drug release characteristi

297 further applied to synthesize porous carbon microspheres with various nanoparticle decorations for n

298 gal force and synthesize functional alginate microspheres with various structures and sizes.

299 ss production of various functional alginate microspheres within a few minutes.

300 akup of cylindrical porous structures porous microspheres within the fiber core.Porous polymer fibers