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1 imiting capacity was reached near the column midpoint.
2 e to monetary reward as constrained by sleep midpoint.
3 pendent gating curve as well as shifting the midpoint.
4 SpoIIIE translocation complex at the septal midpoint.
5 epolymerization did not alter the activation midpoint.
6 e was positioned above or below the stimulus midpoint.
7 mixer at temperatures far below the thermal midpoint.
8 ms a ringlike structure (Z-ring) at the cell midpoint.
9 out thermal energy ( RT) at the denaturation midpoint.
10 od solvent conditions and at this transition midpoint.
11 contractile ring ingressed past the spindle midpoint.
12 , faster diffusion, and lower freezing-curve midpoints.
13 t for the observed patterns of species range midpoints.
14 lly failed to predict the pattern of species midpoints.
15 atial patterns of species richness and range midpoints.
16 completed by blind raters at baseline and 5 (midpoint), 10 (end of treatment), and 14 weeks (follow-u
17 new or worse cystoid changes after the study midpoint (13 surgical eyes [54.2%] vs 9 nonsurgical eyes
18 n 693 subjects at DCCT baseline (1983-1989), midpoint (1988-1991), and end (1993) and at EDIC years 4
20 ndividuals at the lowest mtDNA/nDNA quartile midpoint (4.68 mm Hg; 95% CI, 3.03-6.33; P<0.0001), in c
21 rge shift in the conformational equilibrium (midpoint ~600 bar) from the preactive conformation of ag
27 t baseline and significantly higher than the midpoint and end-of-treatment rates in the control group
29 he age ranges of prebomb sharks (reported as midpoint and extent of the 95.4% probability range) reve
30 il to engineer mutants L1 and L2 and deleted midpoint and head-proximal sigma1 IDRs to generate Delta
31 re collected in the fall (baseline), winter (midpoint), and spring (end point) of the 2009-2010 schoo
33 te and cocoa or placebo)-by-trial (baseline, midpoint, and end-of-treatment assessments) interactions
35 e concentrations were collected at baseline, midpoint, and endpoint to assess the mechanism of action
37 (80%), and 20/20 (100%) of those with peak, midpoint, and trough concentrations of antipseudomonal a
38 ed the impact of clinically meaningful peak, midpoint, and trough concentrations of meropenem, imipen
39 of all BC bottles inoculated with the peak, midpoint, and trough concentrations, respectively (P </=
40 (46%), and 14/24 (58%) of bottles with peak, midpoint, and trough concentrations, respectively (P = 0
43 motors in domains further from the filament midpoint are likely to be activated and inactivated firs
46 the early Eocene, providing a geochronologic midpoint assessment of bee pollen-collection strategies.
47 ic reduction of d-Ala-d-Ala, with a response midpoint at approximately 0.06mug/ml vancomycin and with
50 on of two features, touch count and whisking midpoint at touch, was the simplest model that explained
51 nts of species may be drawn towards a single midpoint attractor - a unimodal gradient of environmenta
52 to estimate the location and strength of the midpoint attractor from species occurrence data sampled
55 late oxygens lie more than 4 A away from the midpoint between the nitrogen atoms, indicating that a s
56 y, near the oil sands industrial center (the midpoint between the Syncrude and Suncor upgrader stacks
58 the spindle to position itself at the exact midpoint between the two sets of segregating chromosomes
60 In this task, monkeys tracked the invisible midpoint between two peripheral bars, such that the visu
61 of mitochondrial dysfunction at the disease midpoint but suffer from a severe deficit in mitochondri
62 Z normally assembles into a ring at the cell midpoint, called the Z ring, which is oriented perpendic
63 ere both response sensitivity and transition midpoint can be tuned with high precision over the physi
64 pactful stages of the life cycle across nine-midpoint categories, a payback period and uncertainty an
65 nts a methodology that can be used to derive midpoint characterization factors for water deprivation
66 e the case of annulenes, in which bond-shift midpoints correspond to transition states, for transform
67 nd 70 degrees C were observed, for which the midpoints could be determined accurately by sigmoidal fi
69 compounds 14-17 and 19 exhibited mean graph midpoint cytotoxicity (GI50) values of 21-71 nM in the N
70 correlation between the paired incisions for midpoint depth and side cut angle (correlation coefficie
71 ere 20% uncut anterior, 20% uncut posterior, midpoint depth of 50%, and 90 degrees side cut angle.
74 or, and 42.3+/-6.6% (range, 25.5%-65.4%) for midpoint depth, which all were significantly different f
81 sess the impacts of its process chains on 17 midpoint impact categories using ReCiPe-2008 methodology
82 roduce the Precipitation Reduction Potential midpoint impact representing the change in downwind prec
84 to-gate assessment results indicate that the midpoint impacts associated with producing CNTs are marg
85 rade-offs in energy return on investment and midpoint impacts relative to the base case while remaini
86 de or direction of phase shifts of melatonin midpoint in response to 2 h of light at either 2000 lux
89 h of the following criteria: data collection midpoint in year 1998 or later, study period of a 12-mon
90 eases in monolayers and shifts in activation midpoints in patch-clamp experiments suggested that the
91 and a shift to later peak activity and sleep midpoint, indicative of greater evening orientation amon
92 possible to consistently link the developed midpoint indicators with a later endpoint assessment alo
97 linded research personnel at baseline, study midpoint (median, 6.8 months), and study completion (med
99 he new compounds had cytotoxicity mean-graph midpoint (MGM) GI50 values in the submicromolar (0.033-0
101 beta was more thermotolerant, with a thermal midpoint of 42 degrees C, matching that of rice OsRca-be
103 the epicardial border of the LV apex and the midpoint of a line connecting the origins of the mitral
104 mitochondria, produced by platelets, at the midpoint of a potent mechanism leading to inflammatory r
106 of maximal stenosis and at the rostrocaudal midpoint of a spindle-shaped T2 hyperintensity suggests
108 reas voltage sensor-bound lipids shifted the midpoint of activation dependent on their electrostatic
112 d, with %CVs ranging from 2.7 to 7.8%, and a midpoint of approximately 17 ng/ml with further optimisa
114 ontaining the native CNG channels shifts the midpoint of cGMP dependence from approximately 91 muM in
117 dPR), 25% to 75% of diastole (dPR25-75), and midpoint of diastole (dPRmid), along with Matlab calcula
118 al, in which a single reversal occurs at the midpoint of each session, consistently show anticipation
121 l activity in the evening, delayed sleep and midpoint of intake and had more frequent social jet lag
123 olar cargo begins to exit the Golgi near the midpoint of maturation, significantly before exit of a s
126 lies on determining the pK parameter, the pH midpoint of peptide insertion into the lipid bilayer.
129 by a single deprotonation and occurs with a midpoint of pH 8.8, but surprisingly, the intermediate f
131 In Experiment 3, pigeons searched at the midpoint of rotated arrays in both the presence and abse
132 cid accounts for a nearly 50 mV shift in the midpoint of the activation curve in a direction consiste
134 Introduction of a flexible hinge at the midpoint of the beta3 TMD decoupled the talin-induced ch
136 nD, everywhere on the membrane except at the midpoint of the cell, ensuring midcell positioning of th
138 her, which can result in both a shift of the midpoint of the dose-response curve and a change of the
141 trained to search for a goal located at the midpoint of the hypothetical line connecting two discret
143 ows a hydrophobic layer of about 10 A at the midpoint of the membrane bilayer, which is likely the mo
144 bunit carries a glutamate exposed around the midpoint of the membrane on the external surface of the
146 n miners and with a shorter time between the midpoint of the period of substantial exposure and diagn
148 he maximum deformation occurs at roughly the midpoint of the reaction, while further dimerization cau
149 ate variability (HRV) were measured at rest, midpoint of the session, immediately after the session,
152 loid peptide production by cleavage near the midpoint of the single transmembrane (TM) segment of APP
153 we depleted two proteins that mark the exact midpoint of the spindle during late anaphase, CYK-4 and
154 of the spindle and completed scission at the midpoint of the spindle, even when spindle length or rat
156 o 125-fold, with an average of 6-fold at the midpoint of the treatment to 12-fold after 12 weeks.
157 te a computerised task identifying perceived midpoint of the two glasses (order counterbalanced).
159 on, because ICA-105574 (2 microM) shifts the midpoint of the voltage-dependence of inactivation by >1
160 quired the studies to have a data collection midpoint of the year 2000 or later, to be done in full-y
163 he Azoarcus ribozyme is less flexible at the midpoint of transition in low-charge-density ions than i
166 sensitive to heat degradation, with thermal midpoints of 35 degrees C +/- 0.3 degrees C, the tempera
167 toms forming a cube, in which O atoms are at midpoints of all of its edges, in excellent agreement wi
170 cture form only transiently and are at their midpoints of stability at the boundary region between th
171 isks (RRs) per cohort-specific range between midpoints of the top and bottom quintiles of fatty acid
173 , M129K, and M129C did not affect stability (midpoints of thermal denaturation, T(m) = 65-66 degrees
176 analysed according to the time of melatonin midpoint on the nights before and after light exposure.
178 s are actively positioned either at the cell midpoint or cell poles, but the processes which drive in
179 not significantly increase from baseline at midpoint or end of study (4.1 +/- 0.6, 4.3 +/- 0.3, and
180 th bacteria and whole blood containing peak, midpoint, or trough concentrations and incubated for up
181 ed by fresh whole blood containing the peak, midpoint, or trough plasma concentrations for meropenem,
182 transcription start sites (TSSs) or enhancer midpoints, our analyses show that different locations di
183 ings suggest a key role for an isometric PAC midpoint (PACmp) in modulating TL across generations, su
184 ird deprotonations, with a combined apparent midpoint pH of 10.2, induce transitions to Lys73- or Lys
186 uch as ChIP-seq reads elongation, nucleosome midpoint piling strategy for positioning analyses, or th
187 .06 and g perpendicular = 1.92), but the low midpoint potential (< -570 mV) and instability of the re
188 The mutations had opposite effects on heme midpoint potential (-302, -361, and -427 mV for W66H, wi
189 from NADH, directs one to a lower-reduction midpoint potential (E degrees ) carrier, and the other t
192 nstrated that it is reversibly redox-active (midpoint potential -474.5 mV), indicating that it has th
195 O absorbance spectra, but increased the heme midpoint potential by 88 mV relative to wild-type iNOSox
197 semiquinone by reducing the electrochemical midpoint potential for its formation via the one-electro
199 avior, and the effects of pH on the observed midpoint potential indicated that reductive activation o
203 e reduction is a one-electron process with a midpoint potential of +20 mV, and without a strong-field
205 ling between the Fe(III)/Fe(II) forms with a midpoint potential of +36 +/- 15 mV at pH 7.8 (versus NH
207 pair of quasi-reversible redox peaks with a midpoint potential of -0.225 V and -0.075, cathodic and
210 al of -310 mV via Mia40 with an intermediate midpoint potential of -290 mV to the C130-C133 pair of E
211 trons flowed from Tim13 with a more negative midpoint potential of -310 mV via Mia40 with an intermed
212 d that the AdoMet radical cluster exhibits a midpoint potential of -510 mV, while the auxiliary clust
213 ndicates a one-electron redox feature with a midpoint potential of -550 mV, which is assigned to a [4
214 0 mV, while the auxiliary cluster exhibits a midpoint potential of -765 mV, to our knowledge the lowe
217 nduced spectrometry, we show that PioC has a midpoint potential of 450 mV, contains all the typical f
220 which significantly contributes to the redox midpoint potential of H and the formation of the charge-
222 and -0.1V to +0.1V, a range well-fitting the midpoint potential of minerals naturally reduced by elec
223 A detailed study of the pH dependence of the midpoint potential of skeletal horse myoglobin (Mb) with
224 is an activated process that depends on the midpoint potential of the central aluminum(III) porphyri
225 activity-based titrations indicate that the midpoint potential of the disulfide in AtAPSK is compara
226 re was no significant difference in apparent midpoint potential of the EABs (-0.35V), suggesting that
227 binding to cyt c(1) substantially lowers the midpoint potential of the heme and fully inhibits bc(1)
228 o high light, which coincides with a lowered midpoint potential of the Q(A)/Q(A)(-) redox couple and
232 which the exergonic oxidation of ferredoxin (midpoint potential, -453 mV) is used to drive the unfavo
233 nt negates the ability of TZDs to affect the midpoint potential, suggesting a model of drug binding i
234 he hemes display a large difference in redox midpoint potentials (DeltaEm_b), which in several protei
236 ion in the ferric and ferrous states and the midpoint potentials (E(m) ) of the corresponding redox t
237 onic absorbance and EPR, this method defines midpoint potentials (E(m)) at pH 7.0 of approximately +2
239 g cells into two systems with characteristic midpoint potentials and kinetic behaviors explains prior
241 N338T mutation shifted the first and second midpoint potentials for the FAD from +47 and -30 mV for
242 The insertions result in indicators with midpoint potentials of -229 to -246 mV and are thus bett
243 revealed reversible redox peaks with average midpoint potentials of 80 +/- 5 mV and 72 +/- 5 mV vs. A
244 POR yielded two pairs of redox peaks with midpoint potentials of 90 +/- 5 mV and -300 +/- 10 mV, r
246 ct with thermodynamic considerations, as the midpoint potentials of NAD(P)H do not suffice to support
249 c voltammetry was used to determine that the midpoint potentials of the two hemes in cytochrome c(4)
255 occur on the [4Fe-4S]H subcluster at similar midpoint-potentials (-375 vs -418 mV); the protonation e
258 ppearance of membrane blebs at the poles and midpoint, prior to the formation of enlarged round cells
260 nctions preferentially occur near nucleosome midpoints rather than in internucleosomal linker regions
262 tains a redox-active [4Fe-4S] cluster with a midpoint redox potential (E(m)) of -390 +/- 23 mV (pH 8.
265 capture key properties of CcO, including the midpoint redox potentials of the metal centers and the e
269 .S(gamma) hydrogen bonds as reflected by the midpoint reduction potential, providing direct evidence
270 nal change and effects a major change in the midpoint reduction potentials of the flavin redox couple
271 ium of their FMN subdomains; (ii) the flavin midpoint reduction potentials; and (iii) the kinetics of
272 y switched to reach equilibrium at a similar midpoint regardless of winter habitat or diet suggesting
274 mark their cell division sites at their cell midpoint so that daughter cells are roughly equivalent i
275 magnetic resonance imaging were modeled with midpoint survival analyses, adjusted for PS-quintile.
276 ns in apo-Fet3p unfold sequentially [thermal midpoint (T(m)) of 45 degrees C, 62 degrees C, and 72 de
277 which show a large increase in their thermal midpoints (T(m) 40-43 degrees C) for a DeltaT(m) of 16-1
278 r melting intermediate I(2) had a transition midpoint temperature (T(m)) of 61 degrees C and a CD spe
281 se and xyloglucan on the apparent transition midpoint temperature of the reduced, catalytically activ
282 nown to inhibit Hsf1 activation, lowered the midpoint temperature of trimerization and reduced cooper
285 orresponding to the approximate denaturation midpoint, the combined data are well fit by a combinatio
286 ration of the negative regulator at the cell midpoint, the greatest distance from both cell poles.
288 GC) separations by use of a microfabricated midpoint thermal modulator (muTM) are demonstrated, and
289 FHbp variant, which increased the transition midpoint (Tm) for the N-terminal domain by 8 and 12 degr
290 DNA translocase that localizes to the septal midpoint to mediate chromosome translocation and membran
291 molecular sensing systems with a transition midpoint tunable with 0.1 pH units precision and with a
292 other rod-shaped bacteria select their cell midpoint using such a negatively acting morphogen gradie
295 wo component Boltzmann functions shift their midpoint voltages (Vh) in opposite directions during tre
297 status and when accelerometer-derived sleep midpoint was used as an objective measure of morningness
298 The mean (SD) of the directly localized PPN midpoints was 6.4 mm (0.5) lateral, 3.5 mm (1.0) posteri
300 percentage of disc area, ratio of length to midpoint width, and location relative to the disc margin