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1 of amyloid fibrils in the complex biological milieu.
2 rs confers vulnerability, depending upon the milieu.
3 t resides within a heavily hyperinflammatory milieu.
4 river of the cancer-specific gene expression milieu.
5 lammation in addition to an altered hormonal milieu.
6 s with polar moieties in an otherwise apolar milieu.
7 as a role in regulating the microcirculation milieu.
8 within a robust but ineffective inflammatory milieu.
9 pression reactivates intra-metastasis immune milieu.
10 lization of adherens complexes in APOL1 risk milieu.
11 in alone are released into the extracellular milieu.
12 fected by crowded conditions in the cellular milieu.
13 into established communities in their native milieu.
14 ve microenvironment into a T cell-permissive milieu.
15 sensors designed to operate in physiological milieu.
16 ha-helix conformations in membrane mimicking milieu.
17 high spatial resolution within their native milieu.
18 lite measurements in the tumor extracellular milieu.
19 exposure to neutral pH in the extracellular milieu.
20 l extracellular traps into the extracellular milieu.
21 g the state of their environment or external milieu.
22 ctivation of tissue factor in the thrombotic milieu.
23 t also acts as a signal in the extracellular milieu.
24 shown to promote an immunosuppressive tumor milieu.
25 ring between tumor cells and the surrounding milieu.
26 ctivation and expansion in a complex ex vivo milieu.
27 ncer cell interactions within the peritoneal milieu.
28 al microglial mitochondria into the neuronal milieu.
29 g embryo-initiated modulation of the uterine milieu.
30 ased human tendon tissues in an inflammatory milieu.
31 onents of the available transcription factor milieu.
32 ation before escaping into the extracellular milieu.
33 ter iTreg differentiation in an inflammatory milieu.
34 surface-catalyzed synthesis in the prebiotic milieu.
35 on and infection dynamics within this target milieu.
36 o the liver and exacerbated pro-inflammatory milieu.
37 idative effects in podocytes in the diabetic milieu.
38 ration method can tag a protein in a complex milieu.
39 xylic acid cycle in a normal glucose-replete milieu.
40 igens even in the context of an inflammatory milieu.
41 n signaling through the endogenous G protein milieu.
42 ks lie at the heart of our cities and social milieu.
43 lous due high macromolecular crowding of the milieu.
44 trate in a sequence-promiscuous, hydrophobic milieu.
45 electrophile reactions within the cell lipid milieu.
46 g) cells to create a TH2-polarizing cytokine milieu.
47 red self-assembly of small molecules in cell milieu.
48 ing place in a complex RNA- and protein-rich milieu.
49 fferentiation, depending on the inflammatory milieu.
50 of newly synthesized albumin into the basal milieu.
51 I (IFN-I) chronically present in aged brain milieu.
52 tion through the release of aspirin in tumor milieu.
53 NCys-bearing proteins in complex biological milieu.
54 atures that comprise the adipose thermogenic milieu.
55 is, and thereby promote an anti-inflammatory milieu.
56 nds on activity resulting from their circuit milieu.
57 membrane phospholipids or the intracellular milieu.
58 the backdrop of a dynamic host and microbial milieu.
59 vironments, evolving strategies to sense the milieu.
60 complex assembly in the dense intracellular milieu.
61 hly sensitive to the pH of the extracellular milieu.
62 pro-inflammatory, hypercoagulable background milieu.
63 suppressive effects of the chronic infection milieu.
64 ulation kinetics inside the crowded cellular milieu.
65 sitivity according to the prevailing insulin milieu.
66 l neurogenesis and modulate the inflammatory milieu.
67 efforts to be successful in a dynamic urban milieu.
68 y play out differently in different cultural milieus.
69 r tumors that develop in different endocrine milieus.
70 wever, because enzymes degrade in biological milieus, achieving long-term enzymatic activities can be
72 esis data-that the pH change in the cellular milieu acts through the deprotonation of glutamate 8 to
74 ranslocation, changes in the adaptive immune milieu after infection, increased tissue inflammation an
76 ct target engagement in the complex cellular milieu, along with methods to establish modes of action,
79 et also disturbed the hormone and metabolite milieu and altered expression of growth and metabolic si
80 associated with normalization of CNS immune milieu and concurrent activation of oligodendrocyte prog
82 palmitoylation is regulated by the metabolic milieu and controls plasma membrane partitioning to main
85 recruit new neural progenitors to the tumor milieu and facilitate their maturation into adrenergic i
86 t sapropels developed an analogous elemental milieu and harbored prokaryotes affiliated with fifty-ni
87 that TLR9L induced a suboptimal inflammatory milieu and promoted the antigen-driven expansion and fun
88 lanted human lungs a supportive, physiologic milieu and systemic regulation that resulted in function
90 ct environmental contexts caused by hormonal milieu and their specific society roles, which may trigg
91 nesis, establishment of the correct cellular milieu and trophoblast invasion, all of which involve th
93 ene imprinting, epigenetic factors, hormonal milieu, and chronologic age affect brain development in
94 The brain, sensing the internal and external milieu, and consulting its database, predicts what is li
96 hypothesize that host genetics, the hormonal milieu, and gut microbiota contribute to host-related di
97 for TLRs in regulation of the internal brain milieu, and identify a kinase-regulated mechanism of CSF
98 ) regulatory T cells, increased Th2 cytokine milieu, and induced alternatively activated macrophages
99 ecreased efferocytosis, altered the cytokine milieu, and resulted in suppressed macrophage gene expre
100 ces known to be present in the extracellular milieu, and the response to Ach was recovered by 97.5% a
101 face between the plastic and its surrounding milieu, and thus drives every interaction that this synt
102 ensory impressions of the social and natural milieu are dynamically incorporated into intrinsic brain
104 ells cells exposed to a Th17-differentiating milieu are significantly more resistant to immune suppre
105 dily released in the reductive intracellular milieu as a result of the cleavage of disulfide bonds.
106 re associated with a tumor-promoting colonic milieu as reflected by the high rates of adenomatous pol
108 identify features of the tumor inflammatory milieu associated with immune control of cancer and esta
110 were significant differences in the cytokine milieu between the neoplastic and the surrounding non-ne
112 ripheral origin and the sampling of internal milieu by first order homeostatic neurons within the lam
113 bone and demonstrate that the host nutrient milieu can determine essentiality of bacterial nutrient
114 tal circulation has a distinct immunological milieu characterised by a pathological neutrophil phenot
116 ilation and dysfunction form a prothrombotic milieu characterized by blood stasis and endothelial dys
117 the TME towards a more immunogenic antitumor milieu, characterized by an influx of >20-fold more CD4(
119 goration of goal-directed behavior: internal milieu communicates to first order, need state-selective
120 SWS is associated with a unique endocrine milieu comprising minimum cortisol and high aldosterone,
125 set remained highly responsive to changes in milieu, demonstrated by responses to infused lymphocytes
126 n, but rather relies on the disease-specific milieu driving T-cell subset polarization and autoantige
127 ting in vitro findings that the inflammatory milieu during IDD does not interfere with TonEBP osmoreg
128 e, it is unclear how the underlying cytokine milieu during infection regulates NK cell effector funct
131 tors, as well as cytokines, help establish a milieu favoring either inflammation or resolution of inf
132 riched directly from the endogenous cellular milieu, followed by identification and atomic modeling o
133 orous cell culture inserts established a 3-D milieu for bathing cells while keeping them away from un
134 inflammatory cytokines favoring a permissive milieu for cancer cell growth and invasive behavior.
135 In the absence of an appropriate cytokine milieu for M2 differentiation, Pneumocystis induced an M
138 d in blister fluids also creates a favorable milieu for the recruitment of the CXCR2(+) stem cells, a
139 Tissue-resident macrophages require specific milieus for the maintenance of defining gene-expression
140 these results suggest that the inflammatory milieu found in Crohn's disease could lead to or result
143 y to be stable in the reducing intracellular milieu, glutathione persulfide could serve as a persulfi
144 or recruitment into plaques, in the diabetic milieu, HDL suppressed the general recruitability of mon
145 xosomes from macrophages exposed to diabetic milieu (high glucose or db/db mice) significantly increa
146 munometabolism, epigenetics, or the cytokine milieu holds promise in resolving lung inflammation asso
147 n obesity and contribute to the inflammatory milieu; however, the relationship between signaling even
148 To precisely respond to a changing external milieu, human cells efficiently translate upstream signa
149 ify interactions between MOFs and biological milieu, human whole blood plasma was selected as a model
150 ients evaluating cardiac effects of diabetic milieu (hyperglycemia and insulin resistance) on lipotox
151 nd the assemblies of small molecules in cell milieu, illustrating the functions of the assemblies of
155 uous perioperative hemodynamic and metabolic milieu in high acuity CLKT recipients increases delayed
156 uous perioperative hemodynamic and metabolic milieu in high-acuity CLKT recipients increases delayed
158 rtant biomolecules are present in the tissue milieu in low concentrations and in complex mixtures wit
159 blood vessels, exposed in vivo to a diabetic milieu in mice, also mimic the microvascular changes fou
160 nd can improve the proinflammatory metabolic milieu in patients with moderate to severe CKD through a
162 disordered breast involution on inflammatory milieu in the breast as well as epigenetic reprogramming
163 esults indicate a dominant hyperinflammatory milieu in the circulation and vascular endothelial damag
165 pe leukocyte subpopulations and the cytokine milieu in the lungs and blood of critically ill patients
166 n empirical association between the hormonal milieu in the oviduct and sperm detachment; therefore, w
168 e. growing up or being exposed to a cultural milieu in which dogs are highly valued and integrated in
169 acologically regulated by the FA tone of the milieu in which each operates-COX-1 in the endoplasmic r
172 tween graphene oxide (GO) and the biological milieu, including cells and tissues, are multiplying qui
173 mpaired by insults, which mimic the diabetic milieu, including high glucose and/or fatty levels, and
174 unctionality amid changes in the biochemical milieu, including those relating to energy-transducing m
177 port, the emerging view that the physiologic milieu is a key determinant of amyloid fibril strains.
181 ore, our findings show that the inflammatory milieu is critical in regulating this TCR signal strengt
182 NA double helix, which, in its physiological milieu, is characterized by the iconical Watson-Crick nu
183 Despite the crowded nature of the cellular milieu, ligand-GPCR-G protein interactions are tradition
184 s as well as the alterations in the cytokine milieu, macrophages/monocytes, natural killer cells, T c
185 m by which molecules in the complex cellular milieu may self-organize has generated much excitement a
186 ogether, a complex and bioactive circulating milieu may underlie air pollution-induced cardiovascular
187 e cells and established an immunosuppressive milieu mediated by M2 macrophages, myeloid-derived suppr
188 pro-fibrotic and pro-adipogenic with a rich milieu of activated immune cells responding to microbial
189 tes CRC progression to adenocarcinoma in the milieu of APC(Delta14/+), a phenomenon not found with wi
191 s and thermoregulatory dysfunction against a milieu of decreasing estradiol concentrations during men
192 nervous system and play complex roles in the milieu of diseases including the primary diseases of mye
193 a dynamic process that depends on the local milieu of enzymes, sugar precursors and organelle struct
194 il to closely mimic the Th2 and inflammatory milieu of eosinophilic esophagitis (EoE) and assessed al
197 or probing its interactions with the complex milieu of immune response proteins present in human seru
198 e alterations result in an enrichment of the milieu of infection with EVs carrying signatures from in
199 inflammation, literature characterizing the milieu of inflammatory cytokines and lipid mediators in
201 r potential to emulate the electromechanical milieu of native tissues or conform well with the curved
203 r p62, a protein central to the pathological milieu of PDB, as one of the few noncollagenous human se
204 Although Cannabis contains an overwhelming milieu of terpenoids, only a limited number are currentl
206 nctional mitochondria into the extracellular milieu of the brain, without affecting the release of he
207 ecreted by multiple bacterial species in the milieu of the catheterized urinary tract can directly im
211 one to degradation in the acidic-proteolytic milieu of the gastrointestinal tract, leading to poor or
212 greater knowledge of the intricate cellular milieu of the heart is critical to increase our understa
214 f the morphological, cellular, and molecular milieu of the mammary gland offers insights into the dri
218 colorectal cancer cells affects the cytokine milieu of the tumors, possibly affecting tumor-stroma in
219 Future research should clarify the temporal milieu of these effects and investigate whether individu
222 disassembly, at the acidic pH of the tumour milieu, of pH-sensitive positron-emitting neutral copoly
225 ate in vitro and in vivo effects of diabetic milieu on macrophage cellular/exosome-HuR, alterations i
227 host cell biology to create an intracellular milieu optimally supportive of its replication and sprea
228 ither reduce immune suppression in the tumor milieu or enhance activation of cytotoxic lymphocyte res
229 oduction and that restoration of the hypoxic milieu or estrogen treatment might reverse interneuron g
231 erations in terms of a multifactorial immune milieu, or immunome, to determine potential mechanisms o
232 an early proinflammatory state in the venous milieu, orchestrated by the HIF-induced NLRP3 inflammaso
234 An important component of the inflammatory milieu, PKA internalizes Slack channels from the DRG mem
241 t probes diffusing through the same membrane milieu represents the dynamic resting steady state, whic
242 Interestingly, renewal of the IL-12/IL-10 milieu restores the ability of farnesol-differentiated D
243 sialic acid-containing ligands in the local milieu, resulting in eosinophil apoptosis, inhibition of
245 n and Rijksinstituut voor Volksgezondheid en Milieu (RIVM) in vitro digestion model, respectively.
246 osite directions depending upon the cellular milieu.SIGNIFICANCE STATEMENT Changes in dendritic funct
247 acterial type III effector modifies the host milieu specifically to inhibit competing pathogens with
248 lar enlargement caused by high growth factor milieu starting in pre-diabetic kidneys appears to be a
249 m the population-based Barn/Children Allergy Milieu Stockholm Epidemiology birth cohort were used.
250 01 children from the BAMSE (Children Allergy Milieu Stockholm Epidemiology) birth cohort recruited fr
251 of the following studies: Children, Allergy, Milieu, Stockholm, Epidemiology (BAMSE) (Sweden), Influe
252 anagement Program (CAMP); Children, Allergy, Milieu, Stockholm, Epidemiology (BAMSE); and Genetic Epi
255 Alterations to the brain's Abeta oligomeric milieu, such as during the progression of AD, may theref
258 Since immunoglobulins are part of the immune milieu that C. neoformans confronts in a human host, and
259 les actively released into the extracellular milieu that can harbor genomic, proteomic and lipid carg
260 gate injury and lead to a local and systemic milieu that does not support normal hepatic regeneration
261 ines is complicated by the changing cytokine milieu that drives the phenotypic changes of CTCLs.
262 ns, irritants, and microbes into a cutaneous milieu that facilitates the induction of type 2 immune r
263 of senescent cells generates an inflammatory milieu that leads to chronic tissue damage and contribut
264 have been made in understanding the cytokine milieu that promotes ILC2 responses, how ILC2 responses
265 ng pathways within the Dysf-deficient muscle milieu that regulate cyto-destructive macrophages will p
266 s a crucial role in shaping the inflammatory milieu that supports host protection during infection by
267 ological inducers of ER stress in the tumour milieu, the interplay between oncogenic signalling and E
268 the link between the cortical neurochemical milieu, the tuning of cortical activity, and variability
269 g HIV-1 replication by altering the cellular milieu through targeting factors that include TNPO3.IMPO
270 diffusion of DBPs inside a crowded cellular milieu through, to our knowledge, novel 1D scanning mech
271 R2 protein, overreacted to a proinflammatory milieu (TNF-alpha and IFN-gamma) with increased IL-1beta
272 se outer membrane vesicles into the external milieu to deliver effector molecules that alter the host
273 ime, the spatiotemporal response of the cell milieu to electrophiles, we have designed a fluorogenic
275 the hypothesis that NAC alters the vascular milieu to improve healing of amputation stumps in diabet
276 ransduce sensory signals from the intestinal milieu to the brain through fast neurotransmission onto
278 e migration but also shifts the local immune milieu toward a less inflammatory phenotype in vivo with
279 ROS production and HR, shifting the cellular milieu toward illegitimate recombination events such as
281 as versatile surveyors of the CNS metabolic milieu, tuned to detect conditions of potential metaboli
282 lso function as versatile surveyors of brain milieu, tuned to sense conditions of potential metabolic
283 ntrols inflammatory responses within the CNS milieu under injurious conditions, involving CD200 ligan
285 biological cargo and sense the intracellular milieu, vertical arrays of high aspect ratio nanostructu
289 g the regulation of MCU channel by oxidative milieu, we adapted inflammatory and hypoxia models.
290 ogenesis toward ketogenesis and TCA cycle, a milieu which can hasten oxidative stress and inflammatio
291 e from their binding sites to the accessible milieu, which involves moving through part of the electr
292 , however, often have a suboptimal allograft milieu, which may alter the risk/benefit equation for ES
293 ing of the neuroimmune circuits in the tumor milieu will be instrumental in the development of novel
294 gher for participants grown up in a cultural milieu with a positive attitude toward dogs, which may r
295 ased kidney in favor of an anti-inflammatory milieu with a reduction of pathogenic myeloid cell infil
296 AV-infected LRT depends on the nutrient-rich milieu with increased levels of antioxidants such as asc
297 crosslinking, (4) a decellularized material milieu with potential for future engineering application
298 ion of BAL cells, which samples the cellular milieu within the lower respiratory tract, has not been
300 is associated with a selective inflammatory milieu within which the apoptotic pathway is a cardinal