1 active tropane alkaloid with hypotensive and miotic activity isolated from the Chinese herb Erycibe o

2     Intracameral LAT-A of 5 microM inhibited miotic and accommodative responses to intramuscular PILO

3                                     A marked miotic effect was also observed, with a mean pupil size

4 nd transient adverse events and a consistent miotic effect.

5 as compared between the brimonidine-treated, miotic eye and the untreated eye.

6 nction of stimulus intensity in the treated, miotic eye did not differ from that in the untreated eye

7 in RAPD from baseline (mean = 1.60 dB in the miotic eye, P = 0.007).

8                        Pilocarpine and other miotics have long been suspected to be associated with a

9 us, substantially decreased respiration, and miotic pupils.

10  10 microM had no effect on accommodative or miotic responses to intramuscular PILO.